Cullin-RING Ligases and Protein Neddylation: Biology and Therapeutics (1st ed. 2020) (Advances in Experimental Medicine and Biology #1217)
By: and and
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- Synopsis
- This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, which are activated by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book covers various topics, such as CRL structure, biology, genetics, its regulation by neddylation, its pivotal role in human disease, and its potential in drug discovery and targeted therapies. The book appeals to biochemists and biologists working in other fields, and, given the importance of CRLs in all aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology or medicine.
- Copyright:
- 2020
Book Details
- Book Quality:
- Publisher Quality
- ISBN-13:
- 9789811510250
- Related ISBNs:
- 9789811510243
- Publisher:
- Springer Singapore, Singapore
- Date of Addition:
- 03/05/20
- Copyrighted By:
- Springer Nature Singapore Pte Ltd.
- Adult content:
- No
- Language:
- English
- Has Image Descriptions:
- No
- Categories:
- Nonfiction, Science
- Submitted By:
- Bookshare Staff
- Usage Restrictions:
- This is a copyrighted book.
- Edited by:
- Yi Sun
- Edited by:
- Wenyi Wei
- Edited by:
- Jianping Jin