Fish Analysis for Drug and Chemicals Mediated Cellular Toxicity (1st ed. 2020) (SpringerBriefs in Applied Sciences and Technology)

By: Ajit Kumar Saxena and Amit Kumar

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Synopsis: This book offers a comprehensive overview of drug and chemical cellular toxicity, especially concerning the effects of anticancer drugs (cyclophosphamide, methotrexate and phosphamidon) on chromosomes and proteins. It covers histological changes in rat testis during pre- and postnatal exposure to varied drug doses, along with laboratory findings on arsenic exposure and alcohol consumption producing neurological changes and deleterious effects on reproductive health in animals. The book offers essential information on the role of anticancer drug- / chemical-mediated toxicity in connection with genetic changes in the brain and reproductive health, making it a valuable guide for researchers working in the areas of cancer research, infertility, molecular diagnostics and modern drug discovery, at biochemical and toxicity laboratories, and in genetic predisposition and molecular biology in general.