Molecular Toxicology Protocols (2005) (Methods in Molecular Biology #291)
By:
Sign Up Now!
Already a Member? Log In
You must be logged into UK education collection to access this title.
Learn about membership options,
or view our freely available titles.
- Synopsis
- A collection of cutting-edge techniques for analyzing genotoxic exposure and detecting the resulting biological effects-including endogenous metabolites-up to and including the development of cancer. The authors emphasize analytical methods that can be specifically applied to human populations and patients. Among the applications detailed are the analysis of interactions between such cellular macromolecules as DNA and proteins and chemical and physical agents, the assessment of medically relevant toxicity, and the characterization of genetic alterations induced in transgenic animals by in vivo systems. There are also methods for the analysis of genotoxic exposure during gene expression, of cytotoxicity caused by the induction of apoptosis, of genetic alterations in reporter genes and oncogenes, early (premalignant) detection of altered oncogenes, and of individual variation in biotransformation and DNA repair capacity.
- Copyright:
- 2005
Book Details
- Book Quality:
- Publisher Quality
- Book Size:
- 504 Pages
- ISBN-13:
- 9781592598403
- Related ISBNs:
- 9781588290847
- Publisher:
- Humana Press, Totowa, NJ
- Date of Addition:
- 02/03/21
- Copyrighted By:
- Humana Press, Totowa, NJ
- Adult content:
- No
- Language:
- English
- Has Image Descriptions:
- No
- Categories:
- Nonfiction, Science, Medicine
- Submitted By:
- Bookshare Staff
- Usage Restrictions:
- This is a copyrighted book.
- Edited by:
- Phouthone Keohavong
- Edited by:
- Stephen G. Grant