Modelling and Optimization of Biotechnological Processes: Artificial Intelligence Approaches (2006) (Studies in Computational Intelligence #15)

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Synopsis
Mostindustrialbiotechnologicalprocessesareoperatedempirically.Oneofthe major di?culties of applying advanced control theories is the highly nonlinear nature of the processes. This book examines approaches based on arti?cial intelligencemethods,inparticular,geneticalgorithmsandneuralnetworks,for monitoring, modelling and optimization of fed-batch fermentation processes. The main aim of a process control is to maximize the ?nal product with minimum development and production costs. This book is interdisciplinary in nature, combining topics from biotechn- ogy, arti?cial intelligence, system identi?cation, process monitoring, process modelling and optimal control. Both simulation and experimental validation are performed in this study to demonstrate the suitability and feasibility of proposed methodologies. An online biomass sensor is constructed using a - current neural network for predicting the biomass concentration online with only three measurements (dissolved oxygen, volume and feed rate). Results show that the proposed sensor is comparable or even superior to other sensors proposed in the literature that use more than three measurements. Biote- nological processes are modelled by cascading two recurrent neural networks. It is found that neural models are able to describe the processes with high accuracy. Optimization of the ?nal product is achieved using modi?ed genetic algorithms to determine optimal feed rate pro?les. Experimental results of the corresponding production yields demonstrate that genetic algorithms are powerful tools for optimization of highly nonlinear systems. Moreover, a c- bination of recurrentneural networks and genetic algorithms provides a useful and cost-e?ective methodology for optimizing biotechnological processes.
Copyright:
2006

Book Details

Book Quality:
Publisher Quality
ISBN-13:
9783540324935
Related ISBNs:
9783540306344
Publisher:
Springer Berlin Heidelberg
Date of Addition:
Copyrighted By:
N/A
Adult content:
No
Language:
English
Has Image Descriptions:
No
Categories:
Nonfiction, Science, Computers and Internet, Technology, Medicine
Submitted By:
Bookshare Staff
Usage Restrictions:
This is a copyrighted book.

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