Ancistrocladus Naphthylisoquinoline Alkaloids (1st ed. 2023) (Progress in the Chemistry of Organic Natural Products #119)

By: and and and and and

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Synopsis
This book describes a unique class of secondary metabolites, the mono- and dimeric-naphthylisoquinoline alkaloids. They exclusively occur in lianas of the palaeotropical Ancistrocladaceae and Dioncophyllaceae plant families. Their unprecedented structures include stereogenic centers and rotationally hindered, and therefore stereogenic, axes. Extended recent investigations on six Ancistrocladus species from Asia, as reported in this contribution, shed light on their fascinating phytochemical productivity, with over 100 intriguing natural products. This high chemodiversity arises from a similarly unique biosynthesis from acetate-malonate units, following a novel polyketidic pathway to plant-derived isoquinoline alkaloids. Some of the compounds show most promising anti-parasitic activities. Additionally, strategies for the regio- and stereoselective total synthesis of the alkaloids, including the directed construction of the chiral axis, are also presented.
Copyright:
2023

Book Details

Book Quality:
Publisher Quality
ISBN-13:
9783031104572
Related ISBNs:
9783031104565
Publisher:
Springer International Publishing
Date of Addition:
Copyrighted By:
The Editor
Adult content:
No
Language:
English
Has Image Descriptions:
No
Categories:
Nonfiction, Science, Medicine
Submitted By:
Bookshare Staff
Usage Restrictions:
This is a copyrighted book.
Edited by:
A. Douglas Kinghorn
Edited by:
Heinz Falk
Edited by:
Simon Gibbons
Edited by:
Yoshinori Asakawa
Edited by:
Ji-Kai Liu
Edited by:
Verena M Dirsch

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