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Precision Medicine in Cancer Therapy (Cancer Treatment and Research #178)

by Daniel D. Von Hoff Haiyong Han

This book presents the latest advances in precision medicine in some of the most common cancer types, including hematological, lung and breast malignancies. It also discusses emerging technologies that are making a significant impact on precision medicine in cancer therapy. In addition to describing specific approaches that have already entered clinical practice, the book explores new concepts and tools that are being developed.Precision medicine aims to deliver personalized healthcare tailored to a patient’s genetics, lifestyle and environment, and cancer therapy is one of the areas in which it has flourished in recent years. Documenting the latest advances, this book is of interest to physicians and clinical fellows in the front line of the war on cancer, as well as to basic scientists working in the fields of cancer biology, drug development, biomarker discovery, and biomedical engineering. The contributing authors include translational physicians with first-hand experience in precision patient care.

Precision Medicine, CRISPR, and Genome Engineering: Moving from Association to Biology and Therapeutics (Advances in Experimental Medicine and Biology #1016)

by Stephen H. Tsang George M. Church

This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine. Chapters feature contributions from leaders in stem cell therapy and biology, providing a comprehensive view of the application of gene therapy in numerous fields with an emphasis on ophthalmology, stem cells, and agriculture. The book also highlights recent major technological advances, including ZFN, TALEN, and CRISPR. Precision Medicine, CRISPR, and Genome Engineering is part of the highly successful Advances in Experimental Medicine and Biology series. It is an indispensable resource for researchers and students in genetics as well as clinicians.

Precision Medicine and Distributive Justice: Wicked Problems for Democratic Deliberation

by Leonard M. Fleck

Metastatic cancer and costly precision medicines generate extremely complex problems of health care justice. Targeted cancer therapies yield only very marginal gains in life expectancy for most patients at very great cost, thereby threatening the just allocation of limited health care resources. Philosophers have high hopes for the utility of their theories of justice in addressing the challenges of resource allocation; however, none of these theories can address adequately the "wicked" ethical problems that have resulted from these targeted therapies. What we need instead, bioethicist Leonard M. Fleck argues, is a political conception of health care justice, following Rawls, and a fair and inclusive process of rational democratic deliberation governed by public reason. His account makes the basic assumption that we have only limited health care resources to meet unlimited health care needs generated by emerging medical technologies. The primary ethical and political virtue of rational democratic deliberation is that it allows citizens to fashion autonomously shared understandings of how to fairly address the complex problems of health care justice generated by precision medicine. While ideally just outcomes are a moral and political impossibility, "wicked" problems can metastasize if rationing decisions are made invisibly--in ways effectively hidden from those affected by those decisions. As Fleck demonstrates, a fair and inclusive process of democratic deliberation could make these "wicked" problems visible, and subject, to public reason.

Precision Medicine and Distributive Justice: Wicked Problems for Democratic Deliberation

by Leonard M. Fleck

Metastatic cancer and costly precision medicines generate extremely complex problems of health care justice. Targeted cancer therapies yield only very marginal gains in life expectancy for most patients at very great cost, thereby threatening the just allocation of limited health care resources. Philosophers have high hopes for the utility of their theories of justice in addressing the challenges of resource allocation; however, none of these theories can address adequately the "wicked" ethical problems that have resulted from these targeted therapies. What we need instead, bioethicist Leonard M. Fleck argues, is a political conception of health care justice, following Rawls, and a fair and inclusive process of rational democratic deliberation governed by public reason. His account makes the basic assumption that we have only limited health care resources to meet unlimited health care needs generated by emerging medical technologies. The primary ethical and political virtue of rational democratic deliberation is that it allows citizens to fashion autonomously shared understandings of how to fairly address the complex problems of health care justice generated by precision medicine. While ideally just outcomes are a moral and political impossibility, "wicked" problems can metastasize if rationing decisions are made invisibly--in ways effectively hidden from those affected by those decisions. As Fleck demonstrates, a fair and inclusive process of democratic deliberation could make these "wicked" problems visible, and subject, to public reason.

Precision Medicine (Handbook of Experimental Pharmacology #280)

by Ingolf Cascorbi Matthias Schwab

The rapidly increased understanding of the molecular background of complex diseases facilitated the development of highly advanced therapeutic concepts. Such concepts aiming to consider individual signatures of genomic and proteomic biomarkers including pharmacogenomics as well as advanced diagnostic tools have been successfully implemented in clinical practice in various fields leading to significant improvement of treatment successes. This volume gives an up-to-date overview on applications of precision medicine in various clinical entities, on advanced techniques as well as on economic considerations.

Precision Medicine (Methods in Molecular Biology #2204)

by Tao Huang

This book serves to introduce the technologies and applications of precision medicine. Beginning with a section on emerging experimental and bioinformatics technologies, the collection continues with chapters covering cancer studies, cardiovascular diseases, COPD and systemic lupus erythematosus, as well as the latest engineering and surgical developments in precision medicine. As a volume in the highly successful Methods in Molecular Biology series, this book presents key information from experts in the field. Authoritative and cutting-edge, Precision Medicine covers perspectives of precision medicine from basic research to clinical surgeries, from cancer to cardiovascular disease, from sequencing technology to big data analysis in the hope of broadening the horizons for researchers, engineers, and clinicians and accelerating the interdisciplinary precision medicine research and applications.

Precision Landmark Location for Machine Vision and Photogrammetry: Finding and Achieving the Maximum Possible Accuracy

by José A. Gutierrez Brian S.R. Armstrong

This book addresses the problem of measurement error associated with determining the location of landmarks in images. The least possible photogrammetric uncertainty in a given situation is determined using the Cramér–Rao Lower Bound (CRLB). The monograph provides the reader with: the most complete treatment to date of precision landmark location and the engineering aspects of image capture and processing; detailed theoretical treatment of the CRLB, and more.

Precision in Pulmonary, Critical Care, and Sleep Medicine: A Clinical and Research Guide (Respiratory Medicine)

by Jose L. Gomez Blanca E. Himes Naftali Kaminski

This book serves as the primary reference for precision medicine in the fields of pulmonary, critical care and sleep medicine by documenting principles written by experts in several aspects of precision medicine. It combines fundamental concepts of the field with state-of-the-art studies and how they translate into individual preventive, diagnostic and therapeutic plans. Precision medicine is focused on the integration of individual variability with disease prevention and treatment principles derived from population studies. This concept has risen to prominence in recent years in parallel with advances in genetics, molecular diagnostics and novel target-specific therapies. This fundamental shift in the approach to treatment has broad implications in how we prevent, diagnose and treat disease. Describing key concepts of precision medicine and relating these to pulmonary, critical care and sleep disorders is essential to educate relevant stakeholders and increase the impact of pulmonary precision medicine. The book is organized into seven sections: introduction; genetics; biomarkers; precise phenotyping; mobile health, wearables and telemedicine; precision therapeutics; and enabling widespread adoption of precision medicine. The chapters are organized with an introduction to the specific theme, followed by its basic concepts. They then delve into how these basic concepts relate to the larger theme of precision medicine, new precision medicine approaches to dealing with these problems, and key takeaway points. Liberally illustrated with images, figures, and tables, the text is thorough and intuitive for clinicians and researchers to learn the processes and applications of precision medicine. This is an ideal guide for clinicians to learn new precision medicine concepts in the fields of genetics, genomics, mobile health, and how they apply to their practice and their patients, as well as researchers seeking a basic understanding of precision medicine to assist in designing future research studies.

Precision Health and Medicine: A Digital Revolution in Healthcare (Studies in Computational Intelligence #843)

by Arash Shaban-Nejad Martin Michalowski

This book highlights the latest advances in the application of artificial intelligence to healthcare and medicine. It gathers selected papers presented at the 2019 Health Intelligence workshop, which was jointly held with the Association for the Advancement of Artificial Intelligence (AAAI) annual conference, and presents an overview of the central issues, challenges, and potential opportunities in the field, along with new research results. By addressing a wide range of practical applications, the book makes the emerging topics of digital health and precision medicine accessible to a broad readership. Further, it offers an essential source of information for scientists, researchers, students, industry professionals, national and international public health agencies, and NGOs interested in the theory and practice of digital and precision medicine and health, with an emphasis on risk factors in connection with disease prevention, diagnosis, and intervention.

Precision Haematological Cancer Medicine

by Tariq Mughal

Many experts now consider genetic evaluation to be pivotal for the optimal diagnosis, classification, risk stratification, and therapeutic decision-making for persons diagnosed with blood cancer. This new text specifically focuses on the genetic alterations essential for establishing diagnosis and assesses how they might impact the precision oncology standard of care. Providing an authoritative review of the state of the art, this is essential reading for physicians, hematologists, and oncologists for optimal management of individual patients.

Precision Haematological Cancer Medicine

by Tariq Mughal

Many experts now consider genetic evaluation to be pivotal for the optimal diagnosis, classification, risk stratification, and therapeutic decision-making for persons diagnosed with blood cancer. This new text specifically focuses on the genetic alterations essential for establishing diagnosis and assesses how they might impact the precision oncology standard of care. Providing an authoritative review of the state of the art, this is essential reading for physicians, hematologists, and oncologists for optimal management of individual patients.

Precision Cancer Therapies, Volume 1: Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice

by Owen A. O'Connor Stephen M. Ansell John F. Seymour

Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies A thorough compilation of the many scientific breakthroughs in the ongoing development of precision cancer therapies related to lymphoma Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice focuses on lymphoma, an area which has seen a remarkable number of breakthroughs in the ongoing development of precision cancer therapies. Each section on a specific biology or class of drugs has an introductory chapter written by an authority in the field, exclusively focused on the science and its relevance to cancer biology. This approach addresses the need for scientists, physicians, and the private sector to understand the broader context of the extraordinary advances that have produced such astonishing advances in the disease. The work primarily focuses on how to understand and translate fundamental principles of basic science into information that can be directly applied to patients – hence the subtitle, From Concept to Practice. To aid in readers’ comprehension, the first page of each chapter contains a box entitled ‘Take Home Points’. This short text will highlight the major unique points about the information contained within the chapter. Some of the key topics addressed in the work are as follows: Biological basis of the lymphoid malignancies: fundamental principles of lymphomagenesis and molecular classification of lymphoid malignancies Targeting programmed cell death: principles for understanding the many types of cell death and promising combinations of drugs targeting apoptosis Targeting the PI3K pathway: understanding the intricacies of this complex biology and precisely how targeted drugs can be leveraged therapeutically Targeting the cancer epigenome: pharmacologic features of drugs targeting the epigenome and future prospects for targeting various aspects of epigenetic control Targeting the tumour proteome: understanding the mechanisms of protein degradation in cancer including both older drugs like proteasome inhibitors, and newer PROTAC based approaches Written primarily for scientists and physicians in both the public and private sectors, Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice is a comprehensive reference work for those interested in the growing area of Precision Cancer Therapies. Seamlessly integrating the basic and applied science, this volume will be an indispensable reference for those interested in translating the most important advances in science to innovative novel treatments for patients.

Precision Cancer Therapies, Volume 1: Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice

by Owen A. O’Connor Stephen M. Ansell John F. Seymour

Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies A thorough compilation of the many scientific breakthroughs in the ongoing development of precision cancer therapies related to lymphoma Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice focuses on lymphoma, an area which has seen a remarkable number of breakthroughs in the ongoing development of precision cancer therapies. Each section on a specific biology or class of drugs has an introductory chapter written by an authority in the field, exclusively focused on the science and its relevance to cancer biology. This approach addresses the need for scientists, physicians, and the private sector to understand the broader context of the extraordinary advances that have produced such astonishing advances in the disease. The work primarily focuses on how to understand and translate fundamental principles of basic science into information that can be directly applied to patients – hence the subtitle, From Concept to Practice. To aid in readers’ comprehension, the first page of each chapter contains a box entitled ‘Take Home Points’. This short text will highlight the major unique points about the information contained within the chapter. Some of the key topics addressed in the work are as follows: Biological basis of the lymphoid malignancies: fundamental principles of lymphomagenesis and molecular classification of lymphoid malignancies Targeting programmed cell death: principles for understanding the many types of cell death and promising combinations of drugs targeting apoptosis Targeting the PI3K pathway: understanding the intricacies of this complex biology and precisely how targeted drugs can be leveraged therapeutically Targeting the cancer epigenome: pharmacologic features of drugs targeting the epigenome and future prospects for targeting various aspects of epigenetic control Targeting the tumour proteome: understanding the mechanisms of protein degradation in cancer including both older drugs like proteasome inhibitors, and newer PROTAC based approaches Written primarily for scientists and physicians in both the public and private sectors, Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice is a comprehensive reference work for those interested in the growing area of Precision Cancer Therapies. Seamlessly integrating the basic and applied science, this volume will be an indispensable reference for those interested in translating the most important advances in science to innovative novel treatments for patients.

Precision Cancer Therapies, Immunologic Approaches for the Treatment of Lymphoid Malignancies: From Concept to Practice

by Owen A. O'Connor Stephen M. Ansell John Gribben

Presents timely and authoritative information on the development of precision cancer therapies as applied to hematologic malignancies The Precision Cancer Therapies series focuses on how to understand and translate fundamental basic science into information that can be directly applied to patients to advance care. Each volume of the series integrates the relevant biological concepts and principles necessary for translating this science to practitioners of this science. Precision Cancer Therapies, Volume Two, focuses on sophisticated immunotherapies targeting cancers affecting the blood, bone marrow, and lymph nodes. Edited and authored by the foremost authorities in the field, this comprehensive reference text covers targeting of cell surface receptors, antibody-drug conjugates (ADC), targeting immune checkpoint, targeting macrophages, EBV-directed immunotherapies, tumor-associated antigens (TAA), and chimeric antigen receptor T-cells (CAR-T). Divided into nine sections, Volume Two includes an overview of the history of immunotherapy development in cancer, as well as a concluding section addressing the mechanistic basis and role of immunomodulatory drugs, analytical tools to quantitate immune-mediated effects, and other topics in immunotherapy. Chapters on specific therapeutics or therapeutic classes include a basic explanation of the underlying pathway and target, the pharmacology of the drug/class, relevant preclinical and clinical data, and discussion of clinical management and potential predictive biomarkers of response. This book also: Delivers a definitive, state-of-the-art review of the relevant biology and its importance in the broader context of cancer biology Focuses on agents that mediate cell killing in lymphoma through a variety of immunologic mechanisms Covers FDA-approved drugs and their indications, as well as drugs currently in development Provides information on monotherapy and combination therapy, summary tables of trials, and discussion of toxicity and efficacy Includes boxed sections highlighting major unique points about the information in the chapter Precision Cancer Therapies, Volume Two: Immunologic Approaches for the Treatment of Lymphoid Malignancies, From Concept to Practice is an indispensable resource for medical, scientific, and allied medical professionals, advanced students, and interested general readers with background knowledge in the subject.

Precision Cancer Therapies, Immunologic Approaches for the Treatment of Lymphoid Malignancies: From Concept to Practice

by Owen A. O'Connor Stephen M. Ansell John G. Gribben

Presents timely and authoritative information on the development of precision cancer therapies as applied to hematologic malignancies The Precision Cancer Therapies series focuses on how to understand and translate fundamental basic science into information that can be directly applied to patients to advance care. Each volume of the series integrates the relevant biological concepts and principles necessary for translating this science to practitioners of this science. Precision Cancer Therapies, Volume Two, focuses on sophisticated immunotherapies targeting cancers affecting the blood, bone marrow, and lymph nodes. Edited and authored by the foremost authorities in the field, this comprehensive reference text covers targeting of cell surface receptors, antibody-drug conjugates (ADC), targeting immune checkpoint, targeting macrophages, EBV-directed immunotherapies, tumor-associated antigens (TAA), and chimeric antigen receptor T-cells (CAR-T). Divided into nine sections, Volume Two includes an overview of the history of immunotherapy development in cancer, as well as a concluding section addressing the mechanistic basis and role of immunomodulatory drugs, analytical tools to quantitate immune-mediated effects, and other topics in immunotherapy. Chapters on specific therapeutics or therapeutic classes include a basic explanation of the underlying pathway and target, the pharmacology of the drug/class, relevant preclinical and clinical data, and discussion of clinical management and potential predictive biomarkers of response. This book also: Delivers a definitive, state-of-the-art review of the relevant biology and its importance in the broader context of cancer biology Focuses on agents that mediate cell killing in lymphoma through a variety of immunologic mechanisms Covers FDA-approved drugs and their indications, as well as drugs currently in development Provides information on monotherapy and combination therapy, summary tables of trials, and discussion of toxicity and efficacy Includes boxed sections highlighting major unique points about the information in the chapter Precision Cancer Therapies, Volume Two: Immunologic Approaches for the Treatment of Lymphoid Malignancies, From Concept to Practice is an indispensable resource for medical, scientific, and allied medical professionals, advanced students, and interested general readers with background knowledge in the subject.

Precision Cancer Medicine: Challenges and Opportunities

by Sameek Roychowdhury Eliezer M. Van Allen

Genomic sequencing technologies have augmented the classification of cancer beyond tissue of origin and towards a molecular taxonomy of cancer. This has created opportunities to guide treatment decisions for individual patients with cancer based on their cancer’s unique molecular characteristics, also known as precision cancer medicine. The purpose of this text will be to describe the contribution and need for multiple disciplines working together to deliver precision cancer medicine. This entails a multi-disciplinary approach across fields including molecular pathology, computational biology, clinical oncology, cancer biology, drug development, genetics, immunology, and bioethics. Thus, we have outlined a current text on each of these fields as they work together to overcome various challenges and create opportunities to deliver precision cancer medicine. As trainees and junior faculty enter their respective fields, this text will provide a framework for understanding the role and responsibility for each specialist to contribute to this team science approach.

Precision Cancer Medicine: Role of the Pathologist

by Clive R. Taylor Ralf Huss Bharat Jasani

This book describes the changing role of pathology in aiding reproducible and accurate patient selection for predictive cancer therapy. Particular attention is given to the clinical application of cutting-edge cancer biomarkers to accurately select patients for targeted cancer therapy and how artificial intelligence can improve the precision of treatments. The advent and basis of predictive cancer care, the role of pathologists in translational cancer research, the analysis of cancer samples, the management of biopsy results, and the accuracy of biopsy results are also discussed. Precision Cancer Medicine: Role of the Pathologist details how pathologists can use the latest biomarkers and apply artificial intelligence technology in cancer diagnosis and management. It is also relevant to oncologists and medical practitioners involved in cancer management seeking an up-to-date resource on the topic.

Precision Approaches to Heterogeneity in Asthma (Advances in Experimental Medicine and Biology #1426)

by Allan R. Brasier Nizar N. Jarjour

Asthma is a common chronic respiratory disease that causes substantial morbidity and has been challenging to treat due to its heterogeneous onset, environmental triggers, severity, and treatment response. To update the field on the rapid advances in this field, Precision Approaches to Heterogeneity in Asthma follows its highly successful predecessor, Heterogeneity in Asthma. In this new volume, noted authorities Allan R Brasier and Nizar N Jarjour and a cadre of leaders in the field incorporate new work advancing our understanding of phenotypes (endotypes) of disease, regional variations in ventilation, systems approach to analyzing the findings from studies of inducible phenotypes, and emerging results of biomarker-informed clinical trials. This work will facilitate our current understanding of the spectrum of disease etiology, prognosis, and the likelihood of responding to the range of available therapeutic interventions.

Precision Anticoagulation Medicine: A Practical Guide

by Hadi Goubran Gaafar Ragab Suzy Hassouna

This book provides a practical guide to the use of novel and conventional anticoagulants for a variety of medical conditions and patients profiled. It reviews data for selecting the most appropriate medication for a given presentation based on a patient’s background while highlighting current best practices. Chapters discuss the choice of agents and optimum duration of therapy while including the relevant literature review and evidence. Specific sections focus on the use of anticoagulants in patients with cardiovascular disease, autoimmune and rheumatologic disorders, antiphospholipid syndrome, cancer, and in the surgical contexts. The book also examines anticoagulation in pregnant and lactating women, pediatric and elderly populations, and patients with extreme weights. Intended for use in daily practice, Precision Anticoagulation Medicine - A Practical Guide is an essential resource for physicians and related professionals, residents, fellows, and graduate students in hematology, cardiology, rheumatology, oncology, surgery, anesthesiology, and intensive care.

Precise Neurovascular Anatomy for Radical Hysterectomy

by Shingo Fujii Kentaro Sekiyama

This extraordinary monograph provides the precise neurovascular anatomy involved in open-abdominal radical hysterectomies, information that is essential for surgeons. For the surgical treatment of invasive cervical cancer, E. Wertheim reported the first systematic data on radical hysterectomy in the early 20th century. While Okabayashi’s radical hysterectomy technique, which modified Wertheim’s approach, later became the mainstream choice for the treatment of Stage Ib and IIb cervical cancer in Japan, the anatomy of the pericervical area is still not fully understood. The recent spread of laparoscopic surgery and robotic surgery also requires a clear grasp of the anatomy of the blood vessels in the connective tissues of the female pelvis.Precise Neurovascular Anatomy for Radical Hysterectomy provides comprehensive information on the surgery and surgical steps necessary for the complete preservation of the nerve function of the urinary bladder and rectal-nerve-sparing radical hysterectomy. All illustrations presented in this book were drawn by the first author – a pioneering gynecological surgeon – and reflect real-world procedures. Plus, a total of 4 hours of supplementary videos introducing the history of hysterectomy, the concept and precise anatomy of nerve-sparing radical hysterectomy, and live surgery provide valuable visual aids for professionals. All anatomical features described are essential and practical, and have been refined based on the latest clinical practice. As such, the book offers a valuable resource for all gynecological surgeons and general surgeons with an interest in gynecological oncology.

Précis d’intervention. La sigmoïdectomie laparoscopique pour cancer

by Gérard Champault Hendrik Schimmelpenning

Le cancer colo-rectal est, en termes d’incidence, le cancer digestif le plus fréquent. Plus de 70 % d’entre eux sont localisés sur l’anse sigmoïde du côlon gauche. La colectomie segmentaire sigmoïdienne pour cancer est donc l’un des actes de chirurgie digestive le plus souvent réalisé. L’intérêt de l’abord laparoscopique dans ces circonstances a été reconnu depuis plusieurs années, en termes de réduction des complications pariétales, des douleurs post opératoires, de la rapidité de récupération d’un retour à un état physique normal, d’ordre esthétique même si cela est secondaire, et surtout de qualité de vie, par plusieurs études contrôlées convergentes.

The Precipice: Existential Risk and the Future of Humanity

by Toby Ord

'Toby Ord is today's Carl Sagan. Clear and inspiring, this book leaves us hopeful for a flourishing human future' Christine PetersonThe Precipice is a landmark book that provides a new way of thinking about our time.We live during the most important era of human history. In the twentieth century, we developed the means to destroy ourselves – without developing the moral framework to ensure we won't. This is the Precipice, and how we respond to it will be the most crucial decision of our time.Oxford moral philosopher Toby Ord explores the risks to humanity's future, from the familiar man-made threats of climate change and nuclear war, to the potentially greater, more unfamiliar threats from engineered pandemics and advanced artificial intelligence. With clear and rigorous thinking, Ord calculates the various risk levels, and shows how our own time fits within the larger story of human history. Can we protect the legacy of the hundred billion who have come before us, and secure a future for the trillions that could follow? What can we do, in our present moment, to face the risks head on?A major work that brings together the disciplines of physics, biology, earth and computer science, history, anthropology, statistics, international relations, political science and moral philosophy, The Precipice is a call for a new understand of our age: a major reorientation in the way we see the world, our history, and the role we play in it.*A Guardian Pick for 2020*

Precious Pills: Medicine and Social Change among Tibetan Refugees in India (Epistemologies of Healing #2)

by Audrey Prost

Through an ethnography of the social and medical worlds of a community of Tibetan refugees in India, this book addresses two main questions: first, how has the prolonged displacement of Tibetan refugees affected concepts of health in the exile community? Second, how has exile changed traditional Tibetan medical practices? It explores how social changes linked to exile have influenced concepts of health and illness in the Tibetan refugee community of Dharamsala and by looking at recent changes in the theory and practice of traditional Tibetan medicine investigates the role of traditional Tibetan medicine in sustaining public health in the exile community.

Preceptorship for Newly Registered Nurses (PDF)

by Karen Elcock Kath Sharples

Newly qualified nurses can find their first year of practice a daunting experience. This book is specifically written to support new nurses through the demands of their preceptorship year. Each chapter provides friendly and practical support on the main areas of development needed for new nurses to become confident practitioners.

Preceptorship for Newly Registered Nurses (PDF)

by Kath Sharples Karen Elcock

Newly qualified nurses can find their first year of practice a daunting experience. This book is specifically written to support new nurses through the demands of their preceptorship year. Each chapter provides friendly and practical support on the main areas of development needed for new nurses to become confident practitioners. The book is also designed for use on formal preceptorship programmes and covers each of the areas for professional development outlined in the Department of Health's new Preceptorship Framework (2010). Packed with activities, case studies and down-to-earth advice, this book provides essential support for the newly registered nurse.

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