- Table View
- List View
Microbiome of Finfish and Shellfish
by Arvind Diwan Sanjay N. Harke Archana PancheThis book helps us to understand the importance of the microbiome associated with finfish and shellfish inhabiting different locations and varied environmental and biological situations. It covers modern molecular tools for identifying microbiome composition and their precise identification at the species level. The book also covers the molecular structural composition of individual microbes, metabolite resources from microbiome species, their functional properties, and production aspects. Notable, the book covers the microbiome applications in the gut systems of finfish and shellfish to the digestion, nutrition, growth, reproduction, immune system, and vulnerability of the host to diseases. It also reviews diversity and functional properties, relationships with diseases, health status, data on species-specific metagenomics, and probiotic research. It highlights the relevance of microbial communities for the development of new and innovative bio-products to build bio and pharmaceutical industries, including aquaculture. This book is an invaluable source for researchers and professionals involved in fishery science, fisheries and aquaculture, fish biotechnology, and fish microbiology and pathology
Microdialysis Techniques in Neuroscience (Neuromethods #75)
by Giuseppe Giovanni and Vincenzo MatteoSince its first application, microdialysis has become incredibly popular to study brain function and has been applied with success in different fields from psychopharmacology, neurobiology, and physiology in animals and also humans. Microdialysis Techniques in Neuroscience focuses on the practical aspects of microdialysis in animal and human, highlighting current technical limitations and providing a vision of what is yet to come for the determination of the most disparate compounds in the brain. The book’s contents range from new techniques for detection and quantifying the release of several different neurotransmitters in vitro and in vivo, even in freely moving animals, to sophisticated use of reverse dialysis and the application of microdialysis in pharmacokinetic studies. Each of the sixteen chapters, in fitting with the spirit of the Neuromethods series, contain an introduction that gives a broad overview of a focused topic, followed by an extensive protocol on how the experiments are performed along with invaluable practical advice. Detailed and authoritative, Microdialysis Techniques in Neuroscience will be a valuable reference for students, neuroscientists, and physicians for the use of microdialysis in the study of brain functions and its clinical applications.
The Microenvironment and Vision (The Cell and Developmental Biology of the Eye)
by Joel B. Sheffield S. Robert HilferThe eye has fascinated scientists from the earliest days of biological in vestigation. The diversity of its parts and the precision of their interaction make it a favorite model system for a variety of developmental studies. The eye is a particularly valuable experimental system not only because its tissues provide examples of fundamental processes, but also because it is a prominent and easily accessible structure at very early embryonic ages. In order to provide an open forum for investigators working on all aspects of ocular development, a series of symposia on ocular and visual devel opment was initiated in 1973. A major objective of the symposia has been to foster communication between the basic research worker and the clinical community. It is our feeling that much can be learned on both sides from this interaction. The idea for an informal meeting allowing maximum ex change of ideas originated with Dr. Leon Candeub, who supplied the nec essary driving force that made the series a reality. Each symposium has concentrated on a different aspect of ocular development. Speakers have been selected to approach related topics from different perspectives.
Microfluidic and Compartmentalized Platforms for Neurobiological Research (Neuromethods #103)
by Emilia BiffiThis volume presents cutting-edge techniques to design, fabricate and use compartmentalized microfluidic devices. Chapters encompass axon guidance and manipulation, compartmentalized devices for synapse manipulation, cell populations interaction either in physiological or pathological condition and compartmentalized devices for pharmacological research and drug discovery. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.Authoritative and practical, Microfluidic and Compartmentalized Platforms for Neurobiological Research provides practical skills needed to fabricate, use microfluidics and compartmentalized platforms with neuronal cell cultures as well as the strengths of these exciting devices and their precious contribution in the field of Neuroscience.
Microfluidics for Assisted Reproduction in Animals
by Vinod Kumar YataThis book describes the fundamentals of microfluidics and fabrication methods of microfluidic devices that can be adopted for animal-assisted reproduction. It presents microfluidic methods for sorting highly fertile spermatozoa. This book also describes the application of microfluidics in vitro fertilization and embryo culture. It discusses the use of microfluidics in sperm sexing and the cryopreservation of animal gametes and embryos. Lastly, the book examines the potential opportunities of microfluidics in infertility diagnosis, sperm selection and guidance, oocyte selection, insemination, and embryo monitoring.
Microglia: Methods and Protocols (Methods in Molecular Biology #1041)
by Bertrand Joseph and José Luis VeneroKey discoveries concerning the different biological functions of microglia in health and disease have attracted scientists from various fields. In Microglia: Methods and Protocols, expert researchers in the field detail methods for selection of the key cellular, molecular and biochemical techniques that are used in studying the many and varied functions of this fascinating cell. These methods and techniques include microglia cell culture for studying microglia activation and functions, as well as their interaction with other cell types both in vitro and in vivo. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Microglia: Methods and Protocols is a useful resource for cell biologists, molecular biologists, immunologists, oncologist and neuroscientists.
Microglia in Health and Disease
by Marie-Ève Tremblay Amanda SierraThese past few years have witnessed a revolution in our understanding of microglia, especially since their roles in the healthy central nervous system (CNS) have started to unravel. These cells were shown to actively maintain health, in concert with neurons and other types of CNS cells, providing further insight into their involvement with diseases. Edited by two pioneers in the field, Marie-Ève Tremblay and Amanda Sierra, Microglia in health and disease aims to share with the broader scientific community some of the recent discoveries in microglia research, from a broad perspective, with a collection of 19 chapters from 52 specialists working in 11 countries across 5 continents.To set microglia on the stage, the book begins by explaining briefly who they are, what they do in the healthy and diseased CNS, and how they can be studied. The first section describes in more details their physiological roles in the maturation, function, and plasticity of the CNS, across development, adolescence, adulthood, neuropathic pain, addiction, and aging. The second section focuses on their implication in pathological conditions impairing the quality of life: neurodevelopmental and neuropsychiatric disorders, AIDS, and multiple sclerosis; and in leading causes of death: ischemia and stroke, neurodegenerative diseases, as well as trauma and injury.
Microglia in the Regenerating and Degenerating Central Nervous System
by Wolfgang J. StreitThe study of microglial cells has recently gained importance for those researching degeneration and regeneration. Microglia in the regenerating and degenerating CNS supports the assertion that understanding microglial biology could perhaps be pivotal for unraveling the pathogenetic mechanisms that underlie Alzheimer's disease, In addition, microglia are also critical for understanding the sequelae of traumatic brain and spinal cord injury, and for the important post-traumatic repair processes. This book gives an up to date account of the role of microglia in degeneration and regeneration of the nervous system and reviews their cell function and physiology.
Microlands: The Future of Life on Earth (and Why It’s Smaller Than You Think)
by J. Craig Venter David Ewing Duncan'An epic travelogue, brimming with the excitement of discovery. With characteristic panache, Venter unveils the teeming array of bacteria, viruses, and eukaryotes that crowd our planet's oceans' - Siddhartha Mukherjee'This page-turner gives . . . the thrill of seeing our planet's largest universe through the brilliant, intrepid eyes of the scientist who has done more than anyone to unlock the secrets of life' - Martine Rothblatt'A tour de force . . . Venter has expanded biology's horizons. This book explores microbial life on a global scale, providing cutting-edge solutions to problems of environmental change' - Aristides Patrinos'A ripping tale . . . to revolutionize our understanding of our bodies, the oceans, and the planet' - Jack Gilbert'An exhilarating account of how creative science is accomplished' - Sir Richard J. Roberts'[A] fascinating tour of Planet Microbe' - Bill McKibben'Venter and Duncan expand our scope of what it means to be alive' - Jamie Metzl'Inspiring ... change[s] our ideas of how biology is done' - TelegraphUpon completing his historic work on the Human Genome Project in 2002, J. Craig Venter declared that he would sequence the genetic code of all life on earth. Thus began a fifteen-year quest to collect DNA from the world's oldest and most abundant form of life: microbes. Boarding the Sorcerer II, a 100-foot sailboat turned research vessel, Venter travelled over 65,000 miles around the globe to sample ocean water and the microscopic life within.In this book, Venter and science writer David Ewing Duncan tell the remarkable story of these expeditions and of the momentous discoveries that ensued-of plant-like bacteria that get their energy from the sun, proteins that metabolize vast amounts of hydrogen, and microbes whose genes shield them from ultraviolet light. The result was a massive library of millions of unknown genes, thousands of unseen protein families, and new lineages of bacteria that revealed the unimaginable complexity of life on earth. Yet despite this exquisite diversity, Venter encountered sobering reminders of how human activity is disturbing the delicate microbial ecosystem that nurtures life on earth. In the face of unprecedented climate change, Venter and Duncan show how we can harness the microbial genome to develop alternative sources of energy, food, and medicine that might ultimately avert our destruction.A captivating story of exploration and discovery, this book restores microbes to their rightful place as crucial partners in our evolutionary past and guides to our future.
Micromammals and Macroparasites: From Evolutionary Ecology to Management
by S. Morand B. R. Krasnov R. PoulinThis book provides a comprehensive survey of the diversity and biology of metazoan parasites affecting small mammals, of their impact on host individuals and populations, and of the management implications of these parasites for conservation biology and human welfare. Designed for a broad, multidisciplinary audience, the book is an essential resource for researchers, students, and practitioners alike.
Microorganisms and Autoimmune Diseases (Infectious Agents and Pathogenesis)
by Herman Friedman Noel R. Rose Mauro BendinelliExperts in microbiology and autoimmunity examine the association between microorganisms and the development of specific categories of autoimmune diseases. The opening chapters explore the bacterial induction of diseases considered autoimmune in nature. Subsequent chapters describe the role of viruses in the induction of these diseases and of diseases with an autoimmune component. Specific topics include: the role of streptococcal infection in rheumatic fever and the role of Klebsiella in the development of ankylosing spondylitis.
Microraptor (Ultimate Dinosaurs)
by Ben GarrodWhen hunters become the hunted, they need to adapt or die. To survive, Microraptor took to the skies and became a flying dinosaur, but what happened next? You can find out. Brimming with facts and fun, quizzes and Ask the Expert sections, there are 7 more dinosaur's stories to be told in the Ultimate Dinosaur series.Pop a dinosaur in your pocket! Introductions from Chris Packham, Steve Backshall and Dr Jane Goodall. These are the most up-to-date dino books in 66 million years, also available in audio download!TV scientist, Professor Ben Garrod, is proud to be a geek as he mixes top level science and humour to prove that science is for everyone. Looking at the evolutionary arms race, prey, predators, place, time, groups and species, Ben reveals new-look dinosaurs. Additional sections include: Ask an Expert, New Science and Fossil Finder as well as quizzes to test your dinosaur knowledge.'A celebration of everything that science is really about.' NatSCA'A perfect primer for kids to learn more about the amazing "terrible lizards".' BBC Wildlife Magazine'He's the man! The genius is his knowledge; the genius is the man himself!' Chris Evans, Virgin Radio Breakfast Show'Shines a fresh, contemporary light on this ever-popular topic.' The Bookseller'Collectable and eye-catching, with plenty of diagrams and illustrations.' Books for Keeps
MicroRNAs as Tools in Biopharmaceutical Production
by Niall BarronFocused manuscript on the potential use/role of miRNAs in bioprocessing, specifically the production of complex proteins in mammalian cells. With that in mind I propose a draft list of topics/chapters along the following lines: Intro on CHO/bioprocessing/engineering challenges to set scene, Genomic organization, biogenesis and mode of action, Identifying miRNA targets: Computational prediction, transcriptomics, proteomices, UTR analysis, etc., miRNA expression in Chinese Hamster Ovary cells, miRNAs as engineering targets: pathway manipulation to impact bioprocess phenotypes, miRNAs as biomarkers, Detection methods: Northern, PCR, hybridization arrays, Next Gen Seq, Manipulation of expression in cultured cells: Transient/stable disregulation, Knockout.
Microstructure and Properties of High-Temperature Superconductors
by I. A. ParinovThis book provides a comprehensive presentation of all types of HTSC and includes a broad overview on HTSC computer simulations and modeling. Especial attention is devoted to the Bi-Sr-Ca-Cu-O and Y-Ba-Cu-O families that today are the most perspective for applications. The book includes a great number of illustrations and references. The monograph is addressed to students, post-graduate students and specialists, taking part in the development, preparation and researching of new materials.
The Middle Ear: Science, Otosurgery, and Technology (Springer Handbook of Auditory Research #46)
by Sunil Puria, Richard R. Fay and Arthur N. PopperThe middle ear plays a vital role in the sense and sensitivity of hearing. Of the various characteristics that distinguish mammals from other vertebrates, several pertain specifically to the middle-ear system, such as the presence of three middle-ear bones and the four-layer composite structure of the tympanic membrane. The Middle Ear attempts to elucidate the role this system plays in sound transmission, as viewed from both scientific and clinical perspectives.
MIDNIGHT (Warriors: The New Prophecy #1)
by Erin HunterIn the exciting second Warriors story arc, the wild cats of the forest have lived in peace and harmony for many moons – but new prophecies from their warrior ancestors speak of a mysterious destiny and grave danger for the clans. Now the time has come for a new generation of heroes to arise, as the quest to save the warrior cats begins…
The Midnight Foxes (Tiger Days #2)
by Sarah LeanMeet animal lover, Tiger Days! A brand-new young fiction series about animals, friendship and adventure by bestselling author Sarah Lean. Beautiful black-and-white illustrations throughout.
The Midnight Hour
by Laura Trinder Benjamin ReadEmily's parents have vanished into the secret world of the Midnight Hour – a Victorian London frozen in time – home to magic and monsters. Emily must find them in the city of the Night Folk, armed only with a packed lunch, a stowaway hedgehog and her infamously big mouth. With bloodthirsty creatures on her tail, Emily has to discover the truth to rescue her parents. What family secret connects her to the Midnight Hour? And can she save both worlds before she runs out of sandwiches?
Midnight Lady: Book 5 (Horses of Half Moon Ranch #5)
by Jenny OldfieldWhen Kirstie watches a neighbouring rancher break in new horses, she is appalled by the treatment of one strong-willed mare - Midnight Lady. Determined to save the horse, Kirstie attempts to free her. But her plan backfires and eight horses escape into the mountains. Now Kirstie is in big trouble - should she own up? If she does, will she ever see Midnight Lady again?
Midnight Magic (Midnight Magic #1)
by Michelle HarrisonBlack cats born at midnight Are different indeed A mischievous, odd And peculiar breed In the middle of winter, three kittens are born in a barn. Two are ordinary, but the third, jet black and born on the stroke of midnight, is brimming with magic from whiskers to tail – even sparking life into a dusty old broomstick! While her siblings pounce at rats, Midnight perfects her flying skills on the broom, not noticing how her mother disapproves of her magical ways… When Midnight finds herself abandoned, the little black kitten sets out to find a new home with only her loyal broom Twiggy at her side. The pair soon befriend a kind-hearted girl called Trixie. But how will Trixie’s family react to Midnight’s extraordinary powers and taste for mischief? A bewitching new series from the best-selling author of A PINCH OF MAGIC, Michelle Harrison. Told in rhyming verse and illustrated in colour throughout, this is perfect for readers of SQUISHY MCFLUFF, HUBBLE BUBBLE and GOBBOLINO. PRAISE FOR MIDNIGHT MAGIC: "This is the perfect next step after picture books with fun rhyming text and sweet illustrations – a gorgeous young fiction book with plenty of sparkle!" – Toppsta
The Midnight Visitor (Museum Kittens #1)
by Holly WebbBrave, clever and never more than a whisker away from adventure! When the museum's visitors are gone for the day, it's time for the cats to come out and play… One stormy night a little black kitten appears on the museum steps. Tabby cat Tasha is delighted to show Peter the museum's passageways and secret corners but the other cats aren't as keen to welcome the new arrival. Determined to prove that Peter is just as much of a museum cat as any of the others, Tasha takes him on a rat hunt. But the pair’s quest almost ends in disaster when they find themselves in the Dinosaur Gallery, with its famous T-Rex skeleton… The first in a charming new series from Holly Webb. Purr-fect for fans of the OTTOLINE books and THE ROYAL RABBITS OF LONDON.
A Midwinter's Tail: the purrfect yuletide story for long winter nights
by Lili HaywardA town in need.An extraordinary cat.A season for miracles...It's nearly Christmas and committed Londoner, Mina Kestle, is close to signing a deal that will make her career and give her everything she's ever wanted. And then she receives a mysterious letter in the post along with an ancient key, sent by her long-estranged godfather . . .Davy Penhallow is an artist who lives on the tiny Cornish island of Morgelyn with only his pet cat, Murr, for company. Mina hasn't seen or heard from him in decades, but now it seems he wants her to look after his cottage - and his cat - while he recovers from a stroke in hospital. Mina doesn't know why Davy has written after all these years, but she intends to do what's right: sort out the cottage and the cat and then get back to London in time for her career-saving meeting, before everything she's built comes crashing down around her. But the more time Mina spends in the cottage, looking after Murr and remembering the magic of Cornish folklore, the harder it becomes for her to tear herself away. And when she discovers that a set of ruthless property developers are coming for Morgelyn, she realises she might be the only one who can stand in their way to save the island, Davy's cottage and Murr's home. As Christmas draws ever closer and echoes of the past - her own and the island's - wash up in her memory, Mina begins to unravel a generation of secrets... and discover what it is she has truly always wanted . . . The perfect magical read to cosy up with on chilly winter nights...
The Mighty Claws Storm A Fortress (The Mighty Claws)
by Nat LurtsemaIt is a hot day in Mighty Claw Valley and Truly, Arty, Bea and Prince have headed out to look for food with Truly’s dad, Wilson. They find a little more than that though. They find a stone fort, selfish Velociraptors, Pterodactyls circling overhead and a pack of Megalosaurs thundering towards them. They went out for lunch and instead they found DANGER.
Migration: Incredible Animal Journeys
by Mike UnwinAnimals of all shapes and sizes make epic journeys across our planet, through harsh weather, avoiding hungry predators, in their efforts to survive. Travel around the globe with some of the world's most incredible animals and discover their unique migration stories. Follow the emperor penguin through snow, ice and bitter temperatures; watch as the great white shark swims 10,000 km in search of seals; track huge herds of elephants, on their yearly hunt for water and be amazed at the millions of red crabs, migrating across Christmas Island.With stunning colour illustrations, uncover the astonishing migrations of 20 creatures, in this truly inspiring narrative. Written by Mike Unwin, a UK Travel Writer of the Year, and illustrated by Jenni Desmond, winner of the New York Times Best Illustrated Children's Book, prepare yourself for a journey like no other.Follow the amazing migrations of these 20 creatures: Arctic tern, barn swallow, bar-headed goose, ruby-throated hummingbird, osprey, wandering albatross, whooping crane, emperor penguin, African elephant, blue wildebeest, caribou, straw-coloured fruit bat, humpback whale, green turtle, Southern pilchard, salmon, great white shark, monarch butterfly, globe skimmer dragonfly, Christmas Island red crab
Migration: Incredible Animal Journeys
by Mike UnwinAnimals of all shapes and sizes make epic journeys across our planet, through harsh weather, avoiding hungry predators, in their efforts to survive. Travel around the globe with some of the world's most incredible animals and discover their unique migration stories. Follow the emperor penguin through snow, ice and bitter temperatures; watch as the great white shark swims 10,000 km in search of seals; track huge herds of elephants, on their yearly hunt for water and be amazed at the millions of red crabs, migrating across Christmas Island.With stunning colour illustrations, uncover the astonishing migrations of 20 creatures, in this truly inspiring narrative. Written by Mike Unwin, a UK Travel Writer of the Year, and illustrated by Jenni Desmond, winner of the New York Times Best Illustrated Children's Book, prepare yourself for a journey like no other.Follow the amazing migrations of these 20 creatures: Arctic tern, barn swallow, bar-headed goose, ruby-throated hummingbird, osprey, wandering albatross, whooping crane, emperor penguin, African elephant, blue wildebeest, caribou, straw-coloured fruit bat, humpback whale, green turtle, Southern pilchard, salmon, great white shark, monarch butterfly, globe skimmer dragonfly, Christmas Island red crab