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Cancer on Trial: Oncology as a New Style of Practice
by Peter Keating Alberto CambrosioUntil the early 1960s, cancer treatment consisted primarily of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic courses of chemotherapy as highly questionable. The randomized clinical trials that today sustain modern oncology were relatively rare and prompted stiff opposition from physicians, who were loath to assign patients randomly to competing treatments. Yet today these trials form the basis of medical oncology. How did such a spectacular change occur? How did medical oncology pivot from a nonentity and, in some regards, a reviled practice to the central position it now occupies in modern medicine? In Cancer on Trial Peter Keating and Alberto Cambrosio explore how practitioners established a new style of practice, at the center of which lies the cancer clinical trial. Far from mere testing devices, these trials have become full-fledged experiments that have redefined the practices of clinicians, statisticians, and biologists. Keating and Cambrosio investigate these trials and how they have changed since the 1960s, all the while demonstrating their significant impact on the progression of oncology. A novel look at the institution of clinical cancer research and therapy, this book will be warmly welcomed by historians, sociologists, and anthropologists of science and medicine, as well as clinicians and researchers in the cancer field.
Cancer on Trial: Oncology as a New Style of Practice
by Peter Keating Alberto CambrosioUntil the early 1960s, cancer treatment consisted primarily of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic courses of chemotherapy as highly questionable. The randomized clinical trials that today sustain modern oncology were relatively rare and prompted stiff opposition from physicians, who were loath to assign patients randomly to competing treatments. Yet today these trials form the basis of medical oncology. How did such a spectacular change occur? How did medical oncology pivot from a nonentity and, in some regards, a reviled practice to the central position it now occupies in modern medicine? In Cancer on Trial Peter Keating and Alberto Cambrosio explore how practitioners established a new style of practice, at the center of which lies the cancer clinical trial. Far from mere testing devices, these trials have become full-fledged experiments that have redefined the practices of clinicians, statisticians, and biologists. Keating and Cambrosio investigate these trials and how they have changed since the 1960s, all the while demonstrating their significant impact on the progression of oncology. A novel look at the institution of clinical cancer research and therapy, this book will be warmly welcomed by historians, sociologists, and anthropologists of science and medicine, as well as clinicians and researchers in the cancer field.
Cancer on Trial: Oncology as a New Style of Practice
by Peter Keating Alberto CambrosioUntil the early 1960s, cancer treatment consisted primarily of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic courses of chemotherapy as highly questionable. The randomized clinical trials that today sustain modern oncology were relatively rare and prompted stiff opposition from physicians, who were loath to assign patients randomly to competing treatments. Yet today these trials form the basis of medical oncology. How did such a spectacular change occur? How did medical oncology pivot from a nonentity and, in some regards, a reviled practice to the central position it now occupies in modern medicine? In Cancer on Trial Peter Keating and Alberto Cambrosio explore how practitioners established a new style of practice, at the center of which lies the cancer clinical trial. Far from mere testing devices, these trials have become full-fledged experiments that have redefined the practices of clinicians, statisticians, and biologists. Keating and Cambrosio investigate these trials and how they have changed since the 1960s, all the while demonstrating their significant impact on the progression of oncology. A novel look at the institution of clinical cancer research and therapy, this book will be warmly welcomed by historians, sociologists, and anthropologists of science and medicine, as well as clinicians and researchers in the cancer field.
Cancer on Trial: Oncology as a New Style of Practice
by Peter Keating Alberto CambrosioUntil the early 1960s, cancer treatment consisted primarily of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic courses of chemotherapy as highly questionable. The randomized clinical trials that today sustain modern oncology were relatively rare and prompted stiff opposition from physicians, who were loath to assign patients randomly to competing treatments. Yet today these trials form the basis of medical oncology. How did such a spectacular change occur? How did medical oncology pivot from a nonentity and, in some regards, a reviled practice to the central position it now occupies in modern medicine? In Cancer on Trial Peter Keating and Alberto Cambrosio explore how practitioners established a new style of practice, at the center of which lies the cancer clinical trial. Far from mere testing devices, these trials have become full-fledged experiments that have redefined the practices of clinicians, statisticians, and biologists. Keating and Cambrosio investigate these trials and how they have changed since the 1960s, all the while demonstrating their significant impact on the progression of oncology. A novel look at the institution of clinical cancer research and therapy, this book will be warmly welcomed by historians, sociologists, and anthropologists of science and medicine, as well as clinicians and researchers in the cancer field.
Cancer on Trial: Oncology as a New Style of Practice
by Peter Keating Alberto CambrosioUntil the early 1960s, cancer treatment consisted primarily of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic courses of chemotherapy as highly questionable. The randomized clinical trials that today sustain modern oncology were relatively rare and prompted stiff opposition from physicians, who were loath to assign patients randomly to competing treatments. Yet today these trials form the basis of medical oncology. How did such a spectacular change occur? How did medical oncology pivot from a nonentity and, in some regards, a reviled practice to the central position it now occupies in modern medicine? In Cancer on Trial Peter Keating and Alberto Cambrosio explore how practitioners established a new style of practice, at the center of which lies the cancer clinical trial. Far from mere testing devices, these trials have become full-fledged experiments that have redefined the practices of clinicians, statisticians, and biologists. Keating and Cambrosio investigate these trials and how they have changed since the 1960s, all the while demonstrating their significant impact on the progression of oncology. A novel look at the institution of clinical cancer research and therapy, this book will be warmly welcomed by historians, sociologists, and anthropologists of science and medicine, as well as clinicians and researchers in the cancer field.
Cancer on Trial: Oncology as a New Style of Practice
by Peter Keating Alberto CambrosioUntil the early 1960s, cancer treatment consisted primarily of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic courses of chemotherapy as highly questionable. The randomized clinical trials that today sustain modern oncology were relatively rare and prompted stiff opposition from physicians, who were loath to assign patients randomly to competing treatments. Yet today these trials form the basis of medical oncology. How did such a spectacular change occur? How did medical oncology pivot from a nonentity and, in some regards, a reviled practice to the central position it now occupies in modern medicine? In Cancer on Trial Peter Keating and Alberto Cambrosio explore how practitioners established a new style of practice, at the center of which lies the cancer clinical trial. Far from mere testing devices, these trials have become full-fledged experiments that have redefined the practices of clinicians, statisticians, and biologists. Keating and Cambrosio investigate these trials and how they have changed since the 1960s, all the while demonstrating their significant impact on the progression of oncology. A novel look at the institution of clinical cancer research and therapy, this book will be warmly welcomed by historians, sociologists, and anthropologists of science and medicine, as well as clinicians and researchers in the cancer field.
Cancer Patients, Cancer Pathways: Historical and Sociological Perspectives (Science, Technology and Medicine in Modern History)
by Carsten Timmermann & Elizabeth ToonEleven essays by historians and sociologists examine cancer research and treatment as everyday practice in post-war Europe and North America. These are not stories of inevitable medical progress and obstacles overcome, but of historical contingencies, cultural differences, hope, and often disappointed expectations.
The Cancer Problem: Malignancy in Nineteenth-Century Britain
by Agnes Arnold-ForsterThe Cancer Problem offers the first medical, cultural, and social history of cancer in nineteenth-century Britain. It begins by looking at a community of doctors and patients who lived and worked in the streets surrounding the Middlesex Hospital in London. It follows in their footsteps as they walked the labyrinthine lanes and passages that branched off Tottenham Court Road; then, through seven chapters, its focus expands to successively include the rivers, lakes, and forests of England, the mountains, poverty, and hunger of the four nations of the British Isles, the reluctant and resistant inhabitants of the British Empire, and the networks of scientists and doctors spread across Europe and North America. The Cancer Problem: Malignancy in Nineteenth-Century Britain argues that it was in the nineteenth century that cancer acquired the unique emotional, symbolic, and politicized status it maintains today. Through an interrogation of the construction, deployment, and emotional consequences of the disease's incurability, this book reframes our conceptualization of the relationship between medicine and modern life and reshapes our understanding of chronic and incurable maladies, both past and present.
The Cancer Problem: Malignancy in Nineteenth-Century Britain
by Agnes Arnold-ForsterThe Cancer Problem offers the first medical, cultural, and social history of cancer in nineteenth-century Britain. It begins by looking at a community of doctors and patients who lived and worked in the streets surrounding the Middlesex Hospital in London. It follows in their footsteps as they walked the labyrinthine lanes and passages that branched off Tottenham Court Road; then, through seven chapters, its focus expands to successively include the rivers, lakes, and forests of England, the mountains, poverty, and hunger of the four nations of the British Isles, the reluctant and resistant inhabitants of the British Empire, and the networks of scientists and doctors spread across Europe and North America. The Cancer Problem: Malignancy in Nineteenth-Century Britain argues that it was in the nineteenth century that cancer acquired the unique emotional, symbolic, and politicized status it maintains today. Through an interrogation of the construction, deployment, and emotional consequences of the disease's incurability, this book reframes our conceptualization of the relationship between medicine and modern life and reshapes our understanding of chronic and incurable maladies, both past and present.
Cancer, Radiation Therapy, and the Market (Routledge Studies in the History of Science, Technology and Medicine)
by Barbara Bridgman PerkinsAppraising cancer as a major medical market in the 2010s, Wall Street investors placed their bets on single-technology treatment facilities costing $100-$300 million each. Critics inside medicine called the widely-publicized proton-center boom "crazy medicine and unsustainable public policy." There was no valid evidence, they claimed, that proton beams were more effective than less costly alternatives. But developers expected insurance to cover their centers’ staggeringly high costs and debts. Was speculation like this new to health care? Cancer, Radiation Therapy, and the Market shows how the radiation therapy specialty in the United States (later called radiation oncology) coevolved with its device industry throughout the twentieth-century. Academic engineers and physicians acquired financing to develop increasingly powerful radiation devices, initiated companies to manufacture the devices competitively, and designed hospital and freestanding procedure units to utilize them. In the process, they incorporated market strategies into medical organization and practice. Although palliative benefits and striking tumor reductions fueled hopes of curing cancer, scientific research all too often found serious patient harm and disappointing beneficial impact on cancer survival. This thoroughly documented and provocative inquiry concludes that public health policy needs to re-evaluate market-driven high-tech medicine and build evidence-based health care systems.
Cancer, Radiation Therapy, and the Market: Cancer Guns (Routledge Studies in the History of Science, Technology and Medicine)
by Barbara Bridgman PerkinsAppraising cancer as a major medical market in the 2010s, Wall Street investors placed their bets on single-technology treatment facilities costing $100-$300 million each. Critics inside medicine called the widely-publicized proton-center boom "crazy medicine and unsustainable public policy." There was no valid evidence, they claimed, that proton beams were more effective than less costly alternatives. But developers expected insurance to cover their centers’ staggeringly high costs and debts. Was speculation like this new to health care? Cancer, Radiation Therapy, and the Market shows how the radiation therapy specialty in the United States (later called radiation oncology) coevolved with its device industry throughout the twentieth-century. Academic engineers and physicians acquired financing to develop increasingly powerful radiation devices, initiated companies to manufacture the devices competitively, and designed hospital and freestanding procedure units to utilize them. In the process, they incorporated market strategies into medical organization and practice. Although palliative benefits and striking tumor reductions fueled hopes of curing cancer, scientific research all too often found serious patient harm and disappointing beneficial impact on cancer survival. This thoroughly documented and provocative inquiry concludes that public health policy needs to re-evaluate market-driven high-tech medicine and build evidence-based health care systems.
Cancer Stem Cells: Philosophy And Therapies
by Lucie LaplaneA new therapeutic strategy could break the stalemate in the war on cancer by targeting not all cancerous cells but the small fraction that lie at the root of cancers. Lucie Laplane offers a comprehensive analysis of cancer stem cell theory, based on an original interdisciplinary approach that combines biology, biomedical history, and philosophy.
Cancer Stem Cells: Philosophy And Therapies
by Lucie LaplaneA new therapeutic strategy could break the stalemate in the war on cancer by targeting not all cancerous cells but the small fraction that lie at the root of cancers. Lucie Laplane offers a comprehensive analysis of cancer stem cell theory, based on an original interdisciplinary approach that combines biology, biomedical history, and philosophy.
Cancer Virus: The discovery of the Epstein-Barr Virus
by Dorothy H. Crawford Ingólfur Johannessen Alan B. RickinsonThe Epstein-Barr virus (EBV) was discovered in 1964. At the time, the very idea of a virus underlying a cancer was revolutionary. Cancer is, after all, not catching. Even now, the idea of a virus causing cancer surprises many people. But Epstein-Barr, named after its discoverers, Sir Anthony Epstein and Dr Yvonne Barr, is fascinating for other reasons too. Almost everyone carries it, yet it is only under certain circumstances that it produces disease. It has been associated with different, apparently unrelated, diseases in different populations: Burkitt's Lymphoma, producing tumours in the jaw, in African children; a nasal tumour in China; glandular fever in Europe and the USA; and the majority of cases of Hodgkin's Disease everywhere. This book tells the story of the discovery of the virus, and the recognition of its connection with these various diseases - an account that spans the world and involves some remarkable characters and individual stories.
Cancer Virus Hunters: A History of Tumor Virology
by Gregory J. MorganTraces the history of the study of tumor viruses and its role in driving breakthroughs in cancer research.Worldwide, approximately one-fifth of human cancers are caused by tumor viruses, with hepatitis B virus and HPV being the leading culprits. While the explosive growth in molecular biology in the late twentieth century is well known, the role that the study of tumor viruses has played in driving many of the greatest breakthroughs is not. Without the insights gained by studying tumor viruses, many significant theoretical advancements over the last four decades in cellular and molecular biology would not have been made. More practically, the study of tumor viruses has saved thousands, if not millions, of lives.In Cancer Virus Hunters, Gregory J. Morgan traces the high points in the development of tumor virology, from Peyton Rous's pioneering work on chicken tumors in 1909 to the successful development of an HPV vaccine for cervical cancer in 2006. Morgan offers a novel approach to understanding the interconnectedness of a long series of biomedical breakthroughs, including those that led to seven Nobel prizes. Among other advances, Morgan describes and contextualizes the science that prompted the discoveries of reverse transcriptase, RNA splicing, the tumor suppressor p53, the vaccine for hepatitis B, and the HIV test. He also explores how "cancer virus hunters" have demonstrated the virtue of beginning with a simple system, even when investigating a complex disease like cancer.Based on extensive archival research and over fifty interviews with experts, Cancer Virus Hunters is a tour de force summarizing a century of research to show how discoveries made with tumor viruses came to dominate the contemporary understanding of cancer. By showcasing the scientists themselves, the book makes for an unusually accessible journey through the history of science. It will be of interest to biomedical professionals—especially in oncology, hepatology, and infectious disease—in addition to historians of science and anyone interested in cancer research.
Cancer Ward: A Novel (Virago Modern Classics)
by Aleksandr Solzhenitsyn Alexander Dolberg‘Solzhenitsyn is one of the towering figures of the age, as a writer, as moralist, as hero’ Edward CrankshawAfter years in enforced exile on the Kazakhstan steppes, a cancer diagnosis brings Oleg Kostoglotov to Ward 13. Brutally treated in squalid conditions, and faced with ward staff and other patients from across the Soviet Union, Kostoglotov finds himself thrown once again into the gruelling mechanics of a state still haunted by Stalinism. One of the great allegorical masterpieces of world literature, Cancer Ward is both a deeply compassionate study of people facing terminal illness and a brilliant dissection of the “cancerous” Soviet police state. Withdrawn from publication in Russia in 1964, it became, along with One Day in the Life of Ivan Denisovich, a work that awoke the conscience of the world.
The Candidate: What it Takes to Win - and Hold - the White House
by Samuel L. PopkinThere are two winners in every presidential election campaign: The inevitable winner when it begins--such as Rudy Giuliani or Hillary Clinton in 2008--and the inevitable victor after it ends. In The Candidate, Samuel Popkin explains the difference between them. While plenty of political insiders have written about specific campaigns, only Popkin--drawing on a lifetime of presidential campaign experience and extensive research--analyzes what it takes to win the next campaign. The road to the White House is littered with geniuses of campaigns past. Why doesn't practice make perfect? Why is experience such a poor teacher? Why are the same mistakes replayed again and again? Based on detailed analyses of the winners--and losers--of the last 60 years of presidential campaigns, Popkin explains how challengers get to the White House, how incumbents stay there for a second term, and how successors hold power for their party. He looks in particular at three campaigns--George H.W. Bush's muddled campaign for reelection in 1992, Al Gore's flawed campaign for the presidency in 2000, and Hillary Clinton's mismanaged effort to win the nomination in 2008--and uncovers the lessons that Ronald Reagan can teach future candidates about teamwork. Throughout, Popkin illuminates the intricacies of presidential campaigns--the small details and the big picture, the surprising mistakes and the predictable miscues--in a riveting account of what goes on inside a campaign and what makes one succeed while another fails. As Popkin shows, a vision for the future and the audacity to run are only the first steps in a candidate's run for office. To truly survive the most grueling show on earth, presidential hopefuls have to understand the critical factors that Popkin reveals in The Candidate. In the wake of the 2012 election, Popkin's analysis looks remarkably prescient. Obama ran a strong incumbent-oriented campaign but made typical incumbent mistakes, as evidenced by his weak performance in the first debate. The Romney campaign correctly put power in the hands of a strong campaign manager, but it couldn't overcome the weaknesses of the candidate.
The Candidate: What it Takes to Win - and Hold - the White House
by Samuel L. PopkinThere are two winners in every presidential election campaign: The inevitable winner when it begins--such as Rudy Giuliani or Hillary Clinton in 2008--and the inevitable victor after it ends. In The Candidate, Samuel Popkin explains the difference between them. While plenty of political insiders have written about specific campaigns, only Popkin--drawing on a lifetime of presidential campaign experience and extensive research--analyzes what it takes to win the next campaign. The road to the White House is littered with geniuses of campaigns past. Why doesn't practice make perfect? Why is experience such a poor teacher? Why are the same mistakes replayed again and again? Based on detailed analyses of the winners--and losers--of the last 60 years of presidential campaigns, Popkin explains how challengers get to the White House, how incumbents stay there for a second term, and how successors hold power for their party. He looks in particular at three campaigns--George H.W. Bush's muddled campaign for reelection in 1992, Al Gore's flawed campaign for the presidency in 2000, and Hillary Clinton's mismanaged effort to win the nomination in 2008--and uncovers the lessons that Ronald Reagan can teach future candidates about teamwork. Throughout, Popkin illuminates the intricacies of presidential campaigns--the small details and the big picture, the surprising mistakes and the predictable miscues--in a riveting account of what goes on inside a campaign and what makes one succeed while another fails. As Popkin shows, a vision for the future and the audacity to run are only the first steps in a candidate's run for office. To truly survive the most grueling show on earth, presidential hopefuls have to understand the critical factors that Popkin reveals in The Candidate. In the wake of the 2012 election, Popkin's analysis looks remarkably prescient. Obama ran a strong incumbent-oriented campaign but made typical incumbent mistakes, as evidenced by his weak performance in the first debate. The Romney campaign correctly put power in the hands of a strong campaign manager, but it couldn't overcome the weaknesses of the candidate.
Candidate-Centered Campaigns: Political Messages, Winning Personalities, and Personal Appeals
by B. ArbourThe book discussed how contemporary political campaigns are increasingly sensitive to candidate-centered appeals, analyzing the strengths and weaknesses of their own candidate to determine how their personalities, backgrounds, and likability and background fit into a campaign narrative, theme, and issue agenda.
The Candidate's Dilemma: Anticorruptionism and Money Politics in Indonesian Election Campaigns
by Elisabeth KramerIn The Candidate's Dilemma, Elisabeth Kramer tells the story of how three political candidates in Indonesia made decisions to resist, engage in, or otherwise incorporate money politics into their electioneering strategies over the course of their campaigns.As they campaign, candidates encounter pressure from the institutional rules that guide elections, political parties, and voters, and must also negotiate complex social relationships to remain competitive. For anticorruption candidates, this context presents additional challenges for building and maintaining their identities. Some of these candidates establish their campaign parameters early and are able to stay their course. For others, the campaign trail results in an avalanche of compromises, each one eating away at their sense of what constitutes "moral" and "acceptable" behavior. The Candidate's Dilemma delves into the lived experiences of candidates to offer a nuanced study of how the political and personal intersect when it comes to money politics, anticorruptionism, and electoral campaigning in Indonesia.
Candidates, Parties and Voters in the Belgian Partitocracy
by Audrey Vandeleene Lieven De Winter Pierre BaudewynsThis book focuses on the triadic relationship between electoral candidates and the two other poles of the delegation and accountability triangle—political parties and voters. The chapters rely mostly on the Belgian Candidate Survey (CCS project), gathering about 2000 candidates belonging to 15 parties represented in Parliament and running for the 2014 federal and regional elections, and the authors’ conclusions serve at answering broad political science questions linked with elite recruitment, party and candidate electoral strategies, personalisation, party cohesion, and descriptive and substantive representation. Its multilevel semi-open electoral system, atypical federal structure, extreme party system fragmentation and volatility make Belgium an exceptionally rich but complex case that offers findings highly relevant to research on candidates in other democracies.
The Candle and the Guillotine: Revolution and Justice in Lyon, 1789–93 (Berghahn Monographs in French Studies #17)
by Julie Patricia JohnsonAs in a number of France’s major cities, civil war erupted in Lyon in the summer of 1793, ultimately leading to a siege of the city and a wave of mass executions. Using Lyon as a lens for understanding the politics of revolutionary France, this book reveals the widespread enthusiasm for judicial change in Lyon at the time of the Revolution, as well as the conflicts that ensued between elected magistrates in the face of radical democratization. Julie Patricia Johnson’s investigation of these developments during the bloodiest years of the Revolution offers powerful insights into the passions and the struggles of ordinary people during an extraordinary time.
The Candle Factory Girl: A gritty story of deceit and betrayal... (Banbury Street #1)
by Tania Crosse1930's London - A backstreet saga full of hopes, dreams and the fight for survival. Perfect for the fans of Rosie Clarke and Lindsey Hutchinson. Work at Price's Candle Factory in Battersea is tedious for intelligent, seventeen-year-old Hillie Hardwick, but she knows she is lucky to have a job at all. Her home life is no better, as she constantly battles with her exacting and bullying father in order to protect her mother and five younger siblings from his abuse. Her only solace is her loving relationship with the chaotic Parker family and her best friend, Gert Parker. When matters violently escalate for Hillie, smitten Jack-the-Lad Jimmy Baxter seems her only salvation. But could this be the biggest mistake of her life, and should she be looking for protection nearer home? A story that crackles with unease where courage and friendship are the only hope. What readers are saying: 'This is a great saga that packs so much emotion and passion into it that you are swept away' Dash Fan Book Reviews. 'This is a wonderful saga... In my opinion, this is her best book yet. I have no hesitation whatsoever in recommending this one as a truly great read' Good 'N Ready. 'I really enjoyed this book, it has some great characters and I loved the setting!' Donna's Book Blog. 'For me it was a fast read, really well written storyline with characters you get invested in' Holly Senecal, NetGalley.
The Candle Man
by Alex ScarrowJack the Ripper's London...an eerily quiet dining room on the Titanic...and a series of murders that covers two decades.1912. Locked in an eerily quiet dining room on the Titanic, a mysterious man tells a young girl his life story as the ship begins to sink. It all starts in Whitechapel, London in 1888...In the small hours of the night in a darkened Whitechapel alley, young Mary Kelly stumbles upon a man who has been seriously injured and is almost unconscious in the gutter. Mary - down on her luck and desperate to survive - steals his bag and runs off into the night.Two days later, an American gentleman wakes in a hospital bed with no memory of who he is or how he got there. He has suffered a serious head injury, and with no one to help him remember who he is he starts to wonder how he will ever find his way home.One terrible truth links these two lost souls in the dark world of Victorian London - a truth that could ruin the name of the most influential man in the land...Back in 1912, as the Titanic begins its final shuddering descent to the bottom of the frozen, black Atlantic, one man is about to reveal the truth behind a series of murders that have hung like a dark fog over London for more than two decades...the identity of Jack the Ripper.
The Candlelight Murders: The Victorian Murder Mystery Series: 1 (The Victorian Murder Mystery Series #1)
by Gyles Brandreth'As good as Sherlock!!' Reader review ⭐⭐⭐⭐⭐'Just so entertaining to read!' Reader review ⭐⭐⭐⭐⭐'What joy! What a mystery! What a tale!' Reader review ⭐⭐⭐⭐⭐As his eyes adjusted to the gloom of the attic, he saw by the light of guttering candles, stretched out on the floor before him, the body of a young man, his throat cut from ear to ear . . . London, 1889: Famous writer Oscar Wilde is the toast of London town. But when the body of a young man of his acquaintance is found in a dark attic room, surrounded by candles, he knows he can't rest until the killer is behind bars. Appealing to fellow author Arthur Conan Doyle, creator of the great Sherlock Holmes, the pair set out to solve the crime.But unravelling a real-life plot is very different to writing one. Can Wilde and Doyle outsmart the murderer hiding in the shadows, before it's too late? A wonderfully witty and gripping cosy historical mystery to transport you to the grand drawing rooms and back alleys of London. Perfect for fans of Sherlock Holmes, Agatha Christie and Richard Osman. Readers love The Candlelight Murders: 'I devoured this book in mere days and immediately moved on to the second in the series' Reader review ⭐⭐⭐⭐⭐'Exciting, fast paced, at times humorous and with a dramatic denouement at the finish just like any good murder mystery . . . A great read' Reader review ⭐⭐⭐⭐⭐'Entertaining, charming and evocative' Reader review ⭐⭐⭐⭐⭐'This series is just what I needed; immersive, funny, clever, educational, and easy to read in the best of ways' Reader review ⭐⭐⭐⭐⭐'If you are a fan of Sherlock Holmes and of Oscar Wilde, this is the book for you . . . Wonderful . . . The mystery itself is intriguing and the answer is shocking' Reader review ⭐⭐⭐⭐⭐