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Biological Approaches to Rational Drug Design
by David B. Weiner William V. WilliamsThis book exploits an understanding of disease pathogenesis by applying a variety of biological agents to therapy. It provides a broad overview of the current methodologies being applied to biological approaches to rational drug design and in depth analyses of progress in this specific field.
Biological Approaches to Rational Drug Design
by David B. Weiner William V. WilliamsThis book exploits an understanding of disease pathogenesis by applying a variety of biological agents to therapy. It provides a broad overview of the current methodologies being applied to biological approaches to rational drug design and in depth analyses of progress in this specific field.
Biological Aspects of Affective Disorders (ISSN)
by Cornelius KatonaBiological research in the affective disorders has been an international growth industry for several years. Biological Aspects of Affective Disorders is a comprehensive introduction to the biochemical, pharmacological, and genetic aspects constituting the abnormalities that may underline the diseases of depression and mania, together with the current understanding of the clinical features and management of affected patients.It will be of great value especially to young researchers from all disciplines contributing to this area and to trainee psychiatrists.
Biological Aspects of Brain Tumors: Proceedings of the 8th Nikko Brain Tumor Conference, Karatsu (Saga) 1990
by Kazuo TabuchiGrowth activity of brain tumors, metabolism of brain tumors, brain tumors and cytokines, drug resistance of brain tumors, oncogenes and anti-oncogenes, basic studies in brain tumor biology and therapy are presented in this book.
Biological Barriers to Protein Delivery (Pharmaceutical Biotechnology #4)
by Kenneth L. Andus Thomas L. RaubIn response to the tremendous increase in the number of protein and peptide drugs, this treatise critically reviews transport and metabolism mechanisms relating to the delivery of endogenous and recombinant proteins to mammalian organs, tissues, and cells. It will promote fruitful collaboration among academic and industrial scientists in the fields of pharmacology, cell biology, biochemistry, physiology, and immunology.
Biological Basis of Alcohol-Induced Cancer (Advances in Experimental Medicine and Biology #815)
by Vasilis Vasiliou Samir Zakhari Helmut K. Seitz Jan B. HoekIn the recent years, a significant amount of research has emerged connecting the link between alcohol and cancer. The field has rapidly advanced, especially since the complex connection between alcohol and cancer has several unique sub areas that are being investigated. This proceedings volume will contain chapters based upon the presentation of the 2nd International Conference on Alcohol and Cancer in Colorado, 2013. The various topics explore the affects of alcohol on: liver and breast cancer; cell signaling and cancer; stem cells; biomarkers and metabolomics; aerodigestive cancers; cancer and the immune system and more.
The Biological Basis of Clinical Observations
by William T. BlowsAccurate clinical observations are key to good patient care and fundamental to clinical practice. A thorough understanding of the biological science underlying vital observations – such as taking the temperature or measuring the pulse – enables health professionals to make well-informed clinical decisions quickly and accurately. To be fully competent in these basic skills, there is a need to understand not only how and why procedures are performed, but also how results are affected, for example by variation in technique or the health status of the patient. This new edition integrates clear explanations of the techniques involved in these procedures with the biological knowledge which gives them meaning. For each topic, William T. Blows explains the pathological basis for variations in observed results, focusing on relevant anatomy and physiology, genetics and pharmacology and the basic principles of care. This helpful text gives health practitioners at all levels the understanding needed to: Perform clinical observations accurately Make accurate judgements about the patient’s condition Make accurate decisions concerning patient care. In addition to all-new chapters on observations of nutrition; fluid balance and hydration; drug side effects and interactions; skin and pain, the text looks at: Temperature Cardiovascular observations Respiratory observations Urinary and bowel observations Neurological observations The Biological Basis of Clinical Observations is a unique text which integrates explanations of essential procedures with the biological knowledge that underpins practice. It is essential reading for all students preparing for clinical practice.
The Biological Basis of Clinical Observations
by William T. BlowsAccurate clinical observations are key to good patient care and fundamental to clinical practice. A thorough understanding of the biological science underlying vital observations – such as taking the temperature or measuring the pulse – enables health professionals to make well-informed clinical decisions quickly and accurately. To be fully competent in these basic skills, there is a need to understand not only how and why procedures are performed, but also how results are affected, for example by variation in technique or the health status of the patient. This new edition integrates clear explanations of the techniques involved in these procedures with the biological knowledge which gives them meaning. For each topic, William T. Blows explains the pathological basis for variations in observed results, focusing on relevant anatomy and physiology, genetics and pharmacology and the basic principles of care. This helpful text gives health practitioners at all levels the understanding needed to: Perform clinical observations accurately Make accurate judgements about the patient’s condition Make accurate decisions concerning patient care. In addition to all-new chapters on observations of nutrition; fluid balance and hydration; drug side effects and interactions; skin and pain, the text looks at: Temperature Cardiovascular observations Respiratory observations Urinary and bowel observations Neurological observations The Biological Basis of Clinical Observations is a unique text which integrates explanations of essential procedures with the biological knowledge that underpins practice. It is essential reading for all students preparing for clinical practice.
The Biological Basis of Clinical Observations
by William T. BlowsAccurate clinical observations are fundamental to competent and safe healthcare practice. The Biological Basis of Clinical Observations gives readers the understanding needed to perform clinical observations accurately, make accurate judgements about the patient’s condition and make accurate decisions concerning patient care. This useful textbook integrates clear explanations of the techniques involved in making clinical observations, alongside the biological knowledge which gives them meaning. For each topic, it explains the pathological basis for variations in observed results, focusing on relevant anatomy and physiology, genetics and pharmacology and the basic principles of care. In addition to a new chapter on blood tests, the text has been updated throughout. It now incorporates increased coverage of paediatrics, movement and the musculo-skeletal system, the lymphatic system, pregnancy, diabetes, homeostasis and infection, amongst other areas. Topics discussed include: temperature cardiovascular observations respiratory observations urinary and bowel observations neurological observations nutrition fluid balance skin drug side effects, interactions and allergies. The Biological Basis of Clinical Observations is a unique text which integrates explanations of essential procedures with the biological knowledge that underpins practice. It is essential reading for all nursing and health students preparing for clinical practice.
The Biological Basis of Clinical Observations: Clinical Observations
by William T. BlowsAccurate clinical observations are fundamental to competent and safe healthcare practice. The Biological Basis of Clinical Observations gives readers the understanding needed to perform clinical observations accurately, make accurate judgements about the patient’s condition and make accurate decisions concerning patient care. This useful textbook integrates clear explanations of the techniques involved in making clinical observations, alongside the biological knowledge which gives them meaning. For each topic, it explains the pathological basis for variations in observed results, focusing on relevant anatomy and physiology, genetics and pharmacology, and the basic principles of care. In addition to new chapters on blood tests and pregnancy, the text has been updated throughout. It now incorporates increased coverage of paediatrics, movement and the musculo-skeletal system, the lymphatic system, pregnancy, diabetes, homeostasis and infection, among other areas. Topics discussed include: temperature cardiovascular observations respiratory observations urinary and bowel observations neurological observations nutrition fluid balance skin drug side effects, interactions and allergies. The Biological Basis of Clinical Observations is a unique text which integrates explanations of essential procedures with the biological knowledge that underpins practice. It is essential reading for all nursing and health students preparing for clinical practice.
The Biological Basis of Clinical Observations
by William T. BlowsFully updated for its fourth edition, The Biological Basis of Clinical Observations provides readers with the understanding needed to perform clinical observations, make accurate judgements about the patient’s condition and make good decisions concerning patient care. This essential textbook supports safe and effective clinical practice by explaining the techniques involved in making clinical observations, alongside the biological knowledge which gives them meaning. For each topic, it explains the pathological basis for variations in observed results, focusing on relevant anatomy and physiology, genetics and pharmacology, and the basic principles of care. A greatly expanded chapter on pharmacology reflects the increased importance of this subject in the nursing curriculum. Topics discussed include: temperature cardiovascular observations respiratory observations urinary and bowel observations neurological observations • nutrition fluid balance skin pharmacology pregnancy. The Biological Basis of Clinical Observations is a unique text which integrates explanations of essential procedures with the biological knowledge that underpins practice. It is essential reading for all nursing and healthcare students preparing for clinical practice.
The Biological Basis of Clinical Observations
by William T. BlowsFully updated for its fourth edition, The Biological Basis of Clinical Observations provides readers with the understanding needed to perform clinical observations, make accurate judgements about the patient’s condition and make good decisions concerning patient care. This essential textbook supports safe and effective clinical practice by explaining the techniques involved in making clinical observations, alongside the biological knowledge which gives them meaning. For each topic, it explains the pathological basis for variations in observed results, focusing on relevant anatomy and physiology, genetics and pharmacology, and the basic principles of care. A greatly expanded chapter on pharmacology reflects the increased importance of this subject in the nursing curriculum. Topics discussed include: temperature cardiovascular observations respiratory observations urinary and bowel observations neurological observations • nutrition fluid balance skin pharmacology pregnancy. The Biological Basis of Clinical Observations is a unique text which integrates explanations of essential procedures with the biological knowledge that underpins practice. It is essential reading for all nursing and healthcare students preparing for clinical practice.
Biological Basis of Geriatric Oncology (Cancer Treatment and Research #124)
by Lodovico Balducci Martine ExtermannThis volume highlights research issues specific to geriatric oncology in the field of carcinogenesis and cancer prevention and treatment, based on the biologic interactions of cancer and age. It conveys a sustainable way of thinking about cancer and aging.
The Biological Basis of Mental Health
by William T. BlowsThis book explores the underlying biology associated with the pathology of mental health disorders and the related nervous system. Fully revised for this third edition, each chapter has been updated to include the latest research, ideas and concepts in each field, and includes a new chapter on sleep. Integrating up-to-date pharmacological and genetic knowledge with an understanding of environmental factors that impact on human biology, The Biological Basis of Mental Health covers topics including brain development, neural communication, neurotransmitters and receptors, hormones and behaviour, genetic disorders, pharmacology, drug abuse, anxiety, schizophrenia, depression, epilepsy, subcortical degenerative diseases of the brain, dementia, developmental disorders, and sleep. Accessible and engaging, this is an essential text for mental health students, practitioners and educators.
The Biological Basis of Mental Health
by William T. BlowsThis book explores the underlying biology associated with the pathology of mental health disorders and the related nervous system. Fully revised for this third edition, each chapter has been updated to include the latest research, ideas and concepts in each field, and includes a new chapter on sleep. Integrating up-to-date pharmacological and genetic knowledge with an understanding of environmental factors that impact on human biology, The Biological Basis of Mental Health covers topics including brain development, neural communication, neurotransmitters and receptors, hormones and behaviour, genetic disorders, pharmacology, drug abuse, anxiety, schizophrenia, depression, epilepsy, subcortical degenerative diseases of the brain, dementia, developmental disorders, and sleep. Accessible and engaging, this is an essential text for mental health students, practitioners and educators.
The Biological Basis of Mental Health
by William T. BlowsThis book explores the underlying biology and neuroscience associated with mental health and wellbeing. This fully revised fourth edition includes new chapters on behavioural science, and brain-gut and brain-gender connections, as well as expanded content on memory and genetics. Integrating up-to-date pharmacological and genetic research with an understanding of environmental factors that impact on human biology, The Biological Basis of Mental Health covers topics including brain development, neural communication, neurotransmitters and receptors, hormones and behaviour, genetic disorders, pharmacology, substance misuse, anxiety, schizophrenia, depression, epilepsy, subcortical degenerative diseases of the brain, dementia, developmental disorders and sleep. This unique textbook is an essential read for all healthcare students, practitioners and educators with an interest in mental health and neuroscience.
The Biological Basis of Mental Health
by William T. BlowsThis book explores the underlying biology and neuroscience associated with mental health and wellbeing. This fully revised fourth edition includes new chapters on behavioural science, and brain-gut and brain-gender connections, as well as expanded content on memory and genetics. Integrating up-to-date pharmacological and genetic research with an understanding of environmental factors that impact on human biology, The Biological Basis of Mental Health covers topics including brain development, neural communication, neurotransmitters and receptors, hormones and behaviour, genetic disorders, pharmacology, substance misuse, anxiety, schizophrenia, depression, epilepsy, subcortical degenerative diseases of the brain, dementia, developmental disorders and sleep. This unique textbook is an essential read for all healthcare students, practitioners and educators with an interest in mental health and neuroscience.
The Biological Basis of Mental Health Nursing (Second Edition)
by William BlowsWritten by an experienced nurse lecturer who also trained as a mental health nurse, this book explores the underlying biology associated with the pathology of mental health disorders and the related nervous system. Fully revised for this second edition, the text includes three new chapters on brain development,pharmacology and learning, behavioural and developmental disorders. Integrating up-to-date pharmacological and genetic knowledge with an understanding of environmental factors that impact on human biology, The Biological Basis of Mental Health Nursing covers topics including: the physiology of neurotransmission and receptors hormones and mental health the biology of emotions, stress, anxiety and phobic states the biology of substance abuse the pharmacology of psychoactive drugs developmental disorders brain anatomy and development the biology of behaviour genetics and mental health affective disorders: depression, mania and suicide schizophrenia autism and other syndromes the ageing brain and dementia degenerative diseases of the brain epilepsy. Accessibly laid out, with many of diagrams, tables and key points at the end of each chapter, this is an essential text for mental health nursing students, practitioners and educators.
The Biological Basis of Mental Health Nursing (Second Edition) (PDF)
by William BlowsWritten by an experienced nurse lecturer who also trained as a mental health nurse, this book explores the underlying biology associated with the pathology of mental health disorders and the related nervous system. Fully revised for this second edition, the text includes three new chapters on brain development,pharmacology and learning, behavioural and developmental disorders. Integrating up-to-date pharmacological and genetic knowledge with an understanding of environmental factors that impact on human biology, The Biological Basis of Mental Health Nursing covers topics including: the physiology of neurotransmission and receptors hormones and mental health the biology of emotions, stress, anxiety and phobic states the biology of substance abuse the pharmacology of psychoactive drugs developmental disorders brain anatomy and development the biology of behaviour genetics and mental health affective disorders: depression, mania and suicide schizophrenia autism and other syndromes the ageing brain and dementia degenerative diseases of the brain epilepsy. Accessibly laid out, with many of diagrams, tables and key points at the end of each chapter, this is an essential text for mental health nursing students, practitioners and educators.
The Biological Basis of Nursing: Cancer
by William T. BlowsPresenting specialized biological information on what cancer is, this book looks at how it damages the body, and how cancer treatments work. Engaging, accessible and illustrated throughout, this unique text: explains the basic biology of cancer discusses the biology of the wide range of common cancers identifies and explains the biological causes of cancer explains drug action in chemotherapy and analgesia explains the link between diet and cancer, and how diet is important in cancer therapy discusses the biological basis of a range of nursing skills linked to cancer. Providing nurses with the essential knowledge required for working with cancer patients and their families, this book will enable them to work with current and new forms of cancer treatment.
The Biological Basis of Nursing: Cancer
by William T. BlowsPresenting specialized biological information on what cancer is, this book looks at how it damages the body, and how cancer treatments work. Engaging, accessible and illustrated throughout, this unique text: explains the basic biology of cancer discusses the biology of the wide range of common cancers identifies and explains the biological causes of cancer explains drug action in chemotherapy and analgesia explains the link between diet and cancer, and how diet is important in cancer therapy discusses the biological basis of a range of nursing skills linked to cancer. Providing nurses with the essential knowledge required for working with cancer patients and their families, this book will enable them to work with current and new forms of cancer treatment.
Biological Basis of Oncologic Thermotherapy (Clinical Thermology)
by C. Streffer P. Vaupel G. M. HahnStudies on the effects of hyperthermia have aroused great interest in recent years. On the one hand, it has been demonstrated. that hyperthermia may be a useful treatment modality for tumors, in combination with ionizing radia tion or cytotoxic drugs. On the other hand, it is of great scientific interest to study the effects of increased temperature on biological systems. Although hyperthermia has been used in the treatment of cancer for cen turies, its therapeutic success was doubtful. However, since it has been shown that radiation-induced cell killirtg can be remarkably enhanced by hyperthermia, many investigations have been performed with cells in vitro, tumors in situ, and normal tissues. From these studies it has been concluded that many biological phenomena and their characteristics which are found in tumors may be conducive to the use of hyperthermia in cancer therapy. Many researchers are studying the cell-killing mechanisms of heat and fac tors that modify cell thermosensitivity. A very fascinating biological phenomenon is the general observation that living cells can enhance their thermoresistance within hours of heat treatment. The development of such thermotolerance is apparently a universal process, and its mechanism is of general scientific interest. Metabolic and physiological processes are changed during and after hyperthermic treatment. These changes exert a strong feedback on the thermo sensitivity of cells and tissues, and also in fluence the heating characteristics of tissues, especially in tumors.
The Biological Basis of Schizophrenia
by Gwynneth Hemmings W. A. HemmingsFor years lip service has been paid to a belief in a biological basis for schizophrenia, but ,nevertheless psychosocial and psychodynamic "theories" of schizophrenia have been promulgated, and these have detracted from the all important biological work, Eclecticism has ruled the day and has caused considerable confusion, As a result research in schizophrenia has not progressed as fast as it should have done and treatment has been less effective than it could otherwise have been. This book is devoted to a wholly biological approach to the problem of schizophrenia, in the hope that many more workers will enter this exciting field of research. A wide variety of topics is covered, including brain structure; the genetics, pathogenesis and treatment of schizophrenia; a consideration of dietary and immunological factors and finally a chapter on alcoholism as it seems possible that the problems of schizophrenia and addiction are linked. We are grateful to all our contributors and to MTP Press for their enthusiasm for this book. Gwynneth P Hemmings William A Hemmings XI SECTION 1: Structure 1 The brain stem reticular formation K. E. WEBSTER There can be no question that the brain stem reticular lormation no longer exercises the same fascination for neurologists that it did a quarter of a century ago.
Biological Basis of Sex Differences in Psychopharmacology (Current Topics in Behavioral Neurosciences #8)
by Jo C. Neill and Jayashri KulkarniSex matters! Are there differences between the sexes when it comes to brain function and the behaviours that result? This volume attempts to answer this fundamental question. If the answer is ‘yes’ then this should impact upon our approach to treating mental illness in humans, and to modelling it in animals, as we look for aetiological and pharmacological solutions.
Biological Calcification: Normal and Pathological Processes in the Early Stages
by Ermanno BonucciFor the first time, this book offers a critical review of the calcification process of the organic and inorganic phases of mineralized tissues focusing on the earliest phases. It includes a methodological chapter which provides the necessary practical information for making appropriate choices. The book is set to become an important reference source for the shelves of bone densitometry labs across the world.