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Biology and Diseases of the Ferret

by James G. Fox Robert P. Marini

Biology and Diseases of the Ferret, Third Edition has been thoroughly revised and updated to provide a current, comprehensive reference on the ferret. Encyclopedic in scope, it is the only book to focus on the characteristics that make the ferret an important research animal, with detailed information on conditions, procedures, and treatments. Offering basic information on biology, husbandry, clinical medicine, and surgery, as well as unique information on the use of ferrets in biomedical research, Biology and Diseases of the Ferret is an essential resource for investigators using ferrets in the laboratory and for companion animal and comparative medicine veterinarians. The Third Edition adds ten completely new chapters, covering regulatory considerations, black-footed ferret recovery, diseases of the cardiovascular system, viral respiratory disease research, morbillivirus research, genetic engineering, hearing and auditory function, vision and neuroplasticity research, nausea and vomiting research, and lung carcinogenesis research. Additionally, the anesthesia, surgery, and biomethodology chapter has been subdivided into three and thoroughly expanded. The book also highlights the ferret genome project, along with the emerging technology of genetically engineered ferrets, which is of particular importance to the future of the ferret as an animal model in research and will allow the investigation of diseases and their genetic basis in a small, easily maintained, non-rodent species.

Biology and Ecology of Pharmaceutical Marine Life: Echinoderms (Biology and Ecology of Marine Life)

by Ramasamy Santhanam Santhanam Ramesh Sheba Rani Nakka David

The first comprehensive book on the biology and ecology of pharmaceutical echinoderms. Contributed by scientists of both marine biology and pharmacy disciplines. All reported echinoderm species producing secondary metabolites are dealt with. Previously known only as nutritional invertebrates, the contribution of the echinoderms as sources of secondary metabolites for therapeutic compounds is a topic ripe for exploration. All 200+ images are produced in full color. This book provides the taxonomy, common name, global distribution, habitat, diagnostic features and pharmaceutical compounds (along with their activities) of 150 species of ecinoderms along with over 200 detailed illustrations in glorious color. Among the biota of marine habitats, the echinoderms, which include sea stars (starfish), brittle stars and basket stars, sea urchins and sand dollars, sea cucumbers, and sea lilies or feather stars, are known for their importance as promising sources of bioactive compounds for development of pharmaceuticals. Their potential therapeutic applications have been growing rapidly in the treatment of many diseases.

Biology and Ecology of Pharmaceutical Marine Life: Echinoderms (Biology and Ecology of Marine Life)

by Ramasamy Santhanam Santhanam Ramesh Sheba Rani Nakka David

The first comprehensive book on the biology and ecology of pharmaceutical echinoderms. Contributed by scientists of both marine biology and pharmacy disciplines. All reported echinoderm species producing secondary metabolites are dealt with. Previously known only as nutritional invertebrates, the contribution of the echinoderms as sources of secondary metabolites for therapeutic compounds is a topic ripe for exploration. All 200+ images are produced in full color. This book provides the taxonomy, common name, global distribution, habitat, diagnostic features and pharmaceutical compounds (along with their activities) of 150 species of ecinoderms along with over 200 detailed illustrations in glorious color. Among the biota of marine habitats, the echinoderms, which include sea stars (starfish), brittle stars and basket stars, sea urchins and sand dollars, sea cucumbers, and sea lilies or feather stars, are known for their importance as promising sources of bioactive compounds for development of pharmaceuticals. Their potential therapeutic applications have been growing rapidly in the treatment of many diseases.

Biology and Ecology of Pharmaceutical Marine Mollusks

by Ramasamy Santhanam Manavalan Gobinath Santhanam Ramesh

Key features: Serves as a standard reference for researchers, teachers and students of various disciplines such as Fisheries Science, Marine Biology, Life Sciences, Biotechnology, Natural Products, Biochemistry, and Pharmacy, their libraries, and as a valuable guide for pharmaceutical companies involved in the development of new drugs Presents the taxonomy, common name, global distribution, and habitat of 275 species of marine molluscs Provides the diagnostic features and pharmaceutical compounds (along with their chemical structure and activities) of 275 species of marine molluscs Includes more than 500 detailed illustrations Covers bivalves, gastropods, and cephalopods Biology and Ecology of Pharmaceutical Marine Molluscs is the first comprehensive book of its kind written by scientists from both the Marine Biology and Pharmacy disciplines to fill the long-felt need for a marine natural products book devoted exclusively to molluscs. The taxonomy, common name, global distribution, habitat, diagnostic features and pharmaceutical compounds (along with their activities) of 275 species of marine molluscs are given in this comprehensive work, with accompanying illustrations. Bioactive substances isolated from marine invertebrates such as poriferans, coelenterates, molluscs, echinoderms, bryozoans and tunicates have been reported to possess antiviral, antimicrobial, antiprotozoal, antifungal, antihelmintic and anticancer activities. Among the marine invertebrates, marine molluscs have significant commercial applications; for instance, as a source of food, ornaments and production of lime. A few species of molluscs have also been reported to act as scavengers in cleaning the environment and pollution indicators. Recently, many molluscan species have been identified as a potential source of secondary metabolites, having a wide range of pharmaceutical applications. This should be a standard reference for students, researchers and teachers of disciplines such as Pharmacy, Fisheries Science, Marine Biology, Life Sciences, Biotechnology and Biochemistry, as well as a valuable guide for pharmaceutical companies involved in the development of new drugs from marine molluscs.

Biology and Ecology of Pharmaceutical Marine Mollusks (Biology and Ecology of Marine Life)

by Ramasamy Santhanam Manavalan Gobinath Santhanam Ramesh

Key features: Serves as a standard reference for researchers, teachers and students of various disciplines such as Fisheries Science, Marine Biology, Life Sciences, Biotechnology, Natural Products, Biochemistry, and Pharmacy, their libraries, and as a valuable guide for pharmaceutical companies involved in the development of new drugs Presents the taxonomy, common name, global distribution, and habitat of 275 species of marine molluscs Provides the diagnostic features and pharmaceutical compounds (along with their chemical structure and activities) of 275 species of marine molluscs Includes more than 500 detailed illustrations Covers bivalves, gastropods, and cephalopods Biology and Ecology of Pharmaceutical Marine Molluscs is the first comprehensive book of its kind written by scientists from both the Marine Biology and Pharmacy disciplines to fill the long-felt need for a marine natural products book devoted exclusively to molluscs. The taxonomy, common name, global distribution, habitat, diagnostic features and pharmaceutical compounds (along with their activities) of 275 species of marine molluscs are given in this comprehensive work, with accompanying illustrations. Bioactive substances isolated from marine invertebrates such as poriferans, coelenterates, molluscs, echinoderms, bryozoans and tunicates have been reported to possess antiviral, antimicrobial, antiprotozoal, antifungal, antihelmintic and anticancer activities. Among the marine invertebrates, marine molluscs have significant commercial applications; for instance, as a source of food, ornaments and production of lime. A few species of molluscs have also been reported to act as scavengers in cleaning the environment and pollution indicators. Recently, many molluscan species have been identified as a potential source of secondary metabolites, having a wide range of pharmaceutical applications. This should be a standard reference for students, researchers and teachers of disciplines such as Pharmacy, Fisheries Science, Marine Biology, Life Sciences, Biotechnology and Biochemistry, as well as a valuable guide for pharmaceutical companies involved in the development of new drugs from marine molluscs.

Biology and Ecology of Pharmaceutical Marine Plants (Biology and Ecology of Marine Life)

by Ramasamy Santhanam Santhanam Ramesh Hafiz Ansar Suleria

Key features: A standard reference for researchers, teachers and students of Marine Biology, Fisheries Science, Botany/Plant Science, Biotechnology, Natural Products, and Pharmacy, their libraries A valuable guide for pharmaceutical companies involved in the development of new drugs from marine plants Presents the taxonomy, common name, global distribution, and habitat of 400 species of marine plants Provides the diagnostic features and pharmaceutical compounds (along with their chemical structure and activities) of 400 species of marine plants Includes more than 600 detailed illustrations Covers blue-green algae, green algae, brown algae, and red algae Marine plants such as algae (blue-green algae and seaweeds), seagrasses, mangrove plants, salt-tolerant or salt-loving plants (halophytes) and coastal sand dune plants are known to generate approximately 70% of oxygen on earth, and help regulate oxygen in the atmosphere. These plants are potential sources of nutrients and are also considered valuable for the development of new drugs owing to their unique bioactive compounds. This book provides the taxonomy, common name, global distribution, habitat, diagnostic features and pharmaceutical compounds (along with their activities) of 400 species of marine plants, accompanied by high quality illustrations. Biology and Ecology of Pharmaceutical Marine Plants is the first comprehensive book of its kind written by scientists from both the Marine Biology and Pharmacy disciplines to fill the long-felt need for a marine natural products book devoted exclusively to plants. It should be a standard reference for students, researchers and teachers of disciplines such as Pharmacy, Fisheries Science, Marine Biology, Life Sciences, Biotechnology and Biochemistry, as well as a valuable guide for pharmaceutical companies involved in the development of new drugs from marine plants.

Biology and Ecology of Pharmaceutical Marine Plants (Biology and Ecology of Marine Life)

by Ramasamy Santhanam Santhanam Ramesh Hafiz Ansar Suleria

Key features: A standard reference for researchers, teachers and students of Marine Biology, Fisheries Science, Botany/Plant Science, Biotechnology, Natural Products, and Pharmacy, their libraries A valuable guide for pharmaceutical companies involved in the development of new drugs from marine plants Presents the taxonomy, common name, global distribution, and habitat of 400 species of marine plants Provides the diagnostic features and pharmaceutical compounds (along with their chemical structure and activities) of 400 species of marine plants Includes more than 600 detailed illustrations Covers blue-green algae, green algae, brown algae, and red algae Marine plants such as algae (blue-green algae and seaweeds), seagrasses, mangrove plants, salt-tolerant or salt-loving plants (halophytes) and coastal sand dune plants are known to generate approximately 70% of oxygen on earth, and help regulate oxygen in the atmosphere. These plants are potential sources of nutrients and are also considered valuable for the development of new drugs owing to their unique bioactive compounds. This book provides the taxonomy, common name, global distribution, habitat, diagnostic features and pharmaceutical compounds (along with their activities) of 400 species of marine plants, accompanied by high quality illustrations. Biology and Ecology of Pharmaceutical Marine Plants is the first comprehensive book of its kind written by scientists from both the Marine Biology and Pharmacy disciplines to fill the long-felt need for a marine natural products book devoted exclusively to plants. It should be a standard reference for students, researchers and teachers of disciplines such as Pharmacy, Fisheries Science, Marine Biology, Life Sciences, Biotechnology and Biochemistry, as well as a valuable guide for pharmaceutical companies involved in the development of new drugs from marine plants.

Biology and Ecology of Pharmaceutical Marine Sponges (Biology and Ecology of Marine Life)

by Ramasamy Santhanam Santhanam Ramesh Anbu Jeba Sunilson

Key features: Serves as a standard reference for researchers, teachers and students of various disciplines such as Fisheries Science, Marine Biology, Life Sciences, Biotechnology, Natural Products, and Pharmacy, their libraries, and as a valuable guide for pharmaceutical companies involved in the development of new drugs from marine sponges Presents the taxonomy, common name, global distribution, and habitat of 250 species of marine sponges Provides the diagnostic features and pharmaceutical compounds (along with their chemical structure and activities) of 450 species of marine sponges Includes more than 500 detailed illustrations Biology and Ecology of Pharmaceutical Marine Sponges is the first comprehensive book of its kind written by scientists from both the Marine Biology and Pharmacy disciplines to fill the long-felt need for a marine natural products book devoted exclusively to sponges. Sponges are the most primitive multicelled animals that have existed for 700 - 800 million years. Despite their wide range of functional roles, not much is known about them. Marine sponges are responsible for more than 5,300 pharmaceutical products and some species have the potential to provide future drugs to prevent and treat important medical conditions such as cancer, a range of viral diseases, malaria, and inflammatory diseases. Nucleosides derived from sponges were the basis for the synthesis of Ara-C, the first marine-derived anticancer agent, currently used in the routine treatment of patients with leukemia and lymphoma. Marine sponges are the potential sources of many unique metabolites with anticancer,anti-inflammatory, antibiotic, antiviral, antimalarial, and immune or neurosuppressive properties. Although many bioactives have been discovered in marine sponges, only a few of these compounds have been commercialized. This book hopes to change that, providing the taxonomy, common name, global distribution, habitat, diagnostic features and pharmaceutical compounds (along with their chemical structure and activities) of 450 species of marine sponges, accompanied by high-quality illustrations. The book should be a standard reference for students, researchers and teachers of disciplines such as Fisheries Science, Marine Biology, Biochemistry, Biotechnology and Pharmacy and a valuable guide for pharmaceutical companies involved in the development of new drugs from marine sponges.

Biology and Ecology of Pharmaceutical Marine Sponges (Biology and Ecology of Marine Life)

by Ramasamy Santhanam Santhanam Ramesh Anbu Jeba Sunilson

Key features: Serves as a standard reference for researchers, teachers and students of various disciplines such as Fisheries Science, Marine Biology, Life Sciences, Biotechnology, Natural Products, and Pharmacy, their libraries, and as a valuable guide for pharmaceutical companies involved in the development of new drugs from marine sponges Presents the taxonomy, common name, global distribution, and habitat of 250 species of marine sponges Provides the diagnostic features and pharmaceutical compounds (along with their chemical structure and activities) of 450 species of marine sponges Includes more than 500 detailed illustrations Biology and Ecology of Pharmaceutical Marine Sponges is the first comprehensive book of its kind written by scientists from both the Marine Biology and Pharmacy disciplines to fill the long-felt need for a marine natural products book devoted exclusively to sponges. Sponges are the most primitive multicelled animals that have existed for 700 - 800 million years. Despite their wide range of functional roles, not much is known about them. Marine sponges are responsible for more than 5,300 pharmaceutical products and some species have the potential to provide future drugs to prevent and treat important medical conditions such as cancer, a range of viral diseases, malaria, and inflammatory diseases. Nucleosides derived from sponges were the basis for the synthesis of Ara-C, the first marine-derived anticancer agent, currently used in the routine treatment of patients with leukemia and lymphoma. Marine sponges are the potential sources of many unique metabolites with anticancer,anti-inflammatory, antibiotic, antiviral, antimalarial, and immune or neurosuppressive properties. Although many bioactives have been discovered in marine sponges, only a few of these compounds have been commercialized. This book hopes to change that, providing the taxonomy, common name, global distribution, habitat, diagnostic features and pharmaceutical compounds (along with their chemical structure and activities) of 450 species of marine sponges, accompanied by high-quality illustrations. The book should be a standard reference for students, researchers and teachers of disciplines such as Fisheries Science, Marine Biology, Biochemistry, Biotechnology and Pharmacy and a valuable guide for pharmaceutical companies involved in the development of new drugs from marine sponges.

Biology and Ecology of Sardines and Anchovies

by Konstantinos Ganias

Apart from being commercially and socially significant, anchovies and sardines populations occupy crucial positions in the oceans' ecosystems. Low in the food chain, clupeoids tend towards abundance, as if their purpose in life was to be eaten and fuel the upper levels of marine trophic chains. The present book covers a broad spectrum of topics on

Biology and Ecology of Toxic Pufferfish (Biology and Ecology of Marine Life)

by Ramasamy Santhanam

This is the first comprehensive book on the biology and ecology of pufferfish, also known as blowfish, swellfish, and globefish. Covering 197 species of pufferfish recorded so far from the marine, brackish, and freshwater ecosystems of the world, this important volume expounds on the toxins and associated poisonings of pufferfish. Importantly, the volume also explores the many uses of pufferfish, such as in aquariums, for their nutritional and culinary value, and for their emerging uses in the treatment of pain. Topics covered include: biology and ecology of pufferfish profiles of the world’s marine, brackish, and freshwater pufferfish species characteristics of TTX (tetrodotoxin) and STX (saxitoxin) of pufferfish pufferfish poisoning and symptoms: treatment and management aquarium uses of pufferfish nutritional and pharmaceutical values of pufferfish diseases and parasites of pufferfish and their management

Biology and Ecology of Toxic Pufferfish (Biology and Ecology of Marine Life)

by Ramasamy Santhanam

This is the first comprehensive book on the biology and ecology of pufferfish, also known as blowfish, swellfish, and globefish. Covering 197 species of pufferfish recorded so far from the marine, brackish, and freshwater ecosystems of the world, this important volume expounds on the toxins and associated poisonings of pufferfish. Importantly, the volume also explores the many uses of pufferfish, such as in aquariums, for their nutritional and culinary value, and for their emerging uses in the treatment of pain. Topics covered include: biology and ecology of pufferfish profiles of the world’s marine, brackish, and freshwater pufferfish species characteristics of TTX (tetrodotoxin) and STX (saxitoxin) of pufferfish pufferfish poisoning and symptoms: treatment and management aquarium uses of pufferfish nutritional and pharmaceutical values of pufferfish diseases and parasites of pufferfish and their management

Biology and Ecology of Venomous Marine Snails (Biology and Ecology of Marine Life)

by Ramasamy Santhanam

The first comprehensive volume exclusively on marine cone snails, this book provides descriptions of over 100 species of hazardous marine snails along with their biological and ecological characteristics; the characteristics of conotoxins; information on cone snail injuries and their treatment along with prevention measures; and the therapeutic and medicinal value of conotoxins, including as a powerful nonaddictive painkiller, an epilepsy drug, and more. Over 275 color illustrations accompany the text for easy identification.

Biology and Ecology of Venomous Marine Snails (Biology and Ecology of Marine Life)

by Ramasamy Santhanam

The first comprehensive volume exclusively on marine cone snails, this book provides descriptions of over 100 species of hazardous marine snails along with their biological and ecological characteristics; the characteristics of conotoxins; information on cone snail injuries and their treatment along with prevention measures; and the therapeutic and medicinal value of conotoxins, including as a powerful nonaddictive painkiller, an epilepsy drug, and more. Over 275 color illustrations accompany the text for easy identification.

Biology and Ecology of Venomous Stingrays (Biology and Ecology of Marine Life)

by Ramasamy Santhanam

This comprehensive book provides first-hand information on the diversity, biology, and ecology of venomous stingrays of freshwater, brackish, and marine ecosystems. Each year thousands of injuries to swimmers and surfers are reported, with 750 to 1,500 stingray injuries reported each year in the US alone. As more vacationers spend their leisure time exploring coasts and tropical reefs, often in isolated areas without immediate access to advanced health care, there will be greater potential for stingray injuries. A thorough understanding about the diversity of stingrays of marine and freshwater ecosystems and their injuries and envenomations would largely improve the public health community’s ability to better manage and to prevent stingray injuries. This volume fills that gap.With over 200 photos and illustrations, this book shows the characteristics of venomous stingray families along with other profile information, such as common name, geographical distribution, diagnostic features, reproduction, predators, parasites, the International Union for Conservation of Nature’s conservation status. Importantly, it includes valuable information on stingray injuries, envenomation, and medical management.This volume will be very informative for students of fisheries science, marine biology, aquatic biology, and environmental sciences, and will become a standard reference for marine professionals, health practitioners, and college and university libraries, and as a helpful on-board

Biology and Ecology of Venomous Stingrays (Biology and Ecology of Marine Life)

by Ramasamy Santhanam

This comprehensive book provides first-hand information on the diversity, biology, and ecology of venomous stingrays of freshwater, brackish, and marine ecosystems. Each year thousands of injuries to swimmers and surfers are reported, with 750 to 1,500 stingray injuries reported each year in the US alone. As more vacationers spend their leisure time exploring coasts and tropical reefs, often in isolated areas without immediate access to advanced health care, there will be greater potential for stingray injuries. A thorough understanding about the diversity of stingrays of marine and freshwater ecosystems and their injuries and envenomations would largely improve the public health community’s ability to better manage and to prevent stingray injuries. This volume fills that gap.With over 200 photos and illustrations, this book shows the characteristics of venomous stingray families along with other profile information, such as common name, geographical distribution, diagnostic features, reproduction, predators, parasites, the International Union for Conservation of Nature’s conservation status. Importantly, it includes valuable information on stingray injuries, envenomation, and medical management.This volume will be very informative for students of fisheries science, marine biology, aquatic biology, and environmental sciences, and will become a standard reference for marine professionals, health practitioners, and college and university libraries, and as a helpful on-board

The Biology and Evolution of Trematodes: An Essay on the Biology, Morphology, Life Cycles, Transmissions, and Evolution of Digenetic Trematodes

by K. V. Galaktionov A. Dobrovolskij

The book by K. V. Galaktionov and A. A. Dobrovolskij maintains the tra- tion of monographs devoted to detailed coverage of digenetic tr matodes in the tradition of B. Dawes (1946) and T. A. Ginetsinskaya (1968). In this - spect, the book is traditional in both its form and content. In the beginning (Chapter 1), the authors provide a consistent analysis of the morphological features of all life cycle stages. Importantly, they present a detailed char- terization of sporocysts and rediae whose morphological-functional orga- zation has never been comprehensively described in modern literature. The authors not only list morphological characteristics, but also analyze the functional significance of different morphological structures and hypothesize about their evolution. Special attention is given to specific features of m- phogenesis in all stages of the trematode life cycle. On this basis, the authors provide several original suggestions about the possible origins of morp- logical evolution of the parthenogenetic (asexual) and the hermaphroditic generations. This is followed by a detailed consideration of the various m- phological-biological adaptations that ensure the successful completion of the complex life cycles of these parasites (Chapter 2). Life cycles inherent in different trematodes are subject to a special analysis (Chapter 3). The authors distinguish several basic types of life cycles and suggest an original interpretation of their evolutionary origin. Chapter 4 features the analysis of structure and the dynamics of trematode populations and is unusual for a monograph of this type.

Biology and Management of Lung Cancer (Cancer Treatment and Research #11)

by F. Anthony Greco

Lung cancer remains an extremely difficult neoplasm to treat effectively. A large part of our lack of success in dealing with these patients is related to our empiric therapeutic attempts. Slowly our basic understanding of the lung cancers is improving and techniques are becoming available to allow us to better understand the biology of these neoplasms. This volume reviews several areas of interest in regard to the biologic behavior and characteris­ of lung cancer. tics Chapters deal with the in vitro growth of small cell lung cancer, the inves­ tigation of growth factors in human lung cancer, the production of mono­ clonal antibodies against lung cancer and the application and potential use­ fulness of the human tumor cloning assay in lung cancer management. These avenues of investigation are likely to establish a more scientific basis on which more rational therapy can be designed. Carney and associates have established several continuous small cell lung cancer cell lines in their laboratory. The amine precursor uptake and decar­ boxylation (APUD) properties of this neoplasm have been confirmed by demonstrating the presence of neurosecretory granules and high levels of the APUD enzyme L-dopa decarboxylase. In addition, several new markers have been documented including bombesin, creatine-kinase BB and neuron­ specific enolase. These tumor products along with others may be useful serum markers in patients with small cell lung cancer.

Biology and Management of Multiple Myeloma (Current Clinical Oncology)

by James R. Berenson

Expert physicians and clinical researchers summarize and explain all the recent advances in the biology and treatment of bone marrow-based malignancy. On the biological side, the authors show the characteristics of the malignant cell and describe the significant roles played by oncogenic changes, chromosomal anomalies, Kaposi's sarcoma herpes virus, and cytokines. New epidemiological findings and prognostic factors are also analyzed. On the clinical side, the authors provide a comprehensive review of conventional treatment regimens, as well as a discussion of newer experimental approaches involving immunologic targeting, inhibitors of drug resistance, and antitumor agents.

Biology and Management of Unusual Plasma Cell Dyscrasias

by Todd M. Zimmerman Shaji K. Kumar

This unique book focuses on the non-myeloma plasma cell dyscrasias. A key resource for this group of diseases, the book features the latest in emerging knowledge and therapeutic developments, including novel therapies. Each disease-specific chapter discusses biology, disease course, and appropriate therapeutic interventions, covering plasma cell leukemia, plasmacytoma, POEMS Syndrome and Castleman's Disease, Waldenström macroglobulinemia, immunoglobin deposition disease, and cryoglobulinemic syndromes, among others. The only book dedicated to this intriguing family of diseases, Biology and Management of Unusual Plasma Cell Dyscrasias will be a long-lasting reference for clinicians and scientists alike.

Biology and Mathematics: History and Challenges

by Roger Buis

To formalize the dynamics of living things is to search for invariants in a system that contains an irreducible aspect of “fuzziness”, because biological processes are characterized by their large statistical variability, and strong dependence on temporal and environmental factors. What is essential is the identification of what remains stable in a “living being” that is highly fluctuating. The use of mathematics is not limited to the use of calculating tools to simulate and predict results. It also allows us to adopt a way of thinking that is founded on concepts and hypotheses, leading to their discussion and validation. Instruments of mathematical intelligibility and coherence have gradually “fashioned” the view we now have of biological systems. Teaching and research, fundamental or applied, are now dependent on this new order known as Integrative Biology or Systems Biology.

Biology and Mathematics: History and Challenges

by Roger Buis

To formalize the dynamics of living things is to search for invariants in a system that contains an irreducible aspect of “fuzziness”, because biological processes are characterized by their large statistical variability, and strong dependence on temporal and environmental factors. What is essential is the identification of what remains stable in a “living being” that is highly fluctuating. The use of mathematics is not limited to the use of calculating tools to simulate and predict results. It also allows us to adopt a way of thinking that is founded on concepts and hypotheses, leading to their discussion and validation. Instruments of mathematical intelligibility and coherence have gradually “fashioned” the view we now have of biological systems. Teaching and research, fundamental or applied, are now dependent on this new order known as Integrative Biology or Systems Biology.

Biology and Mechanics of Blood Flows: Part I: Biology (CRM Series in Mathematical Physics)

by Marc Thiriet

This authoritative work presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. The book provides a survey of relevant cell components and processes, with detailed coverage of the electrical and mechanical behaviors of vascular cells, tissues, and organs. Biological and mechanical glossaries are provided.

Biology and Mechanics of Blood Flows: Part II: Mechanics and Medical Aspects (CRM Series in Mathematical Physics)

by Marc Thiriet

This authoritative book presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. This volume contains chapters on anatomy, physiology, continuum mechanics, as well as pathological changes in the vasculature walls including the heart and their treatments. Methods of numerical simulations are given and illustrated in particular by application to wall diseases.

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