- Table View
- List View
Decoding the Antibody Repertoire: High Throughput Sequencing of Multiple Transcripts from Single B Cells (Springer Theses)
by Brandon DeKoskyThis thesis outlines the development of the very first technology for high-throughput analysis of paired heavy and light-chain antibody sequences, opening an entirely new window for antibody discovery and the investigation of adaptive immune responses to vaccines and diseases.Previous methods for high-throughput immune repertoire sequencing have been unable to provide information on the identity of immune receptor pairs encoded by individual B or T lymphocytes. The author directly addresses these limitations by designing two new technologies for sequencing multiple mRNA transcripts from up to 10 million isolated, single cells. The techniques developed in this work have enabled comprehensive interrogation of human B-cell repertoires and have been applied for rapid discovery of new human antibodies, to gain new insights into the development of human antibody repertoires, and for analysis of human immune responses to vaccination and disease.
Decoding the World
by Po Bronson Arvind GuptaA vision of the future where the latest Silicon Valley tech meets cutting-edge genetics.Decoding the World is a buddy adventure about the quest to live meaningfully in a world with such uncertainty. It starts with Po Bronson coming to IndieBio.Arvind Gupta created IndieBio as a laboratory for early biotech startups trying to solve major world problems. Glaciers melting. Dying bees. Infertility. Cancer. Ocean plastic. Pandemics.As they travel around the world, finding scientists to join their cause, the authors bring their first-hand experience to the great mysteries that haunt our future. Natural resource depletion. Job-taking robots. China's global influence.Decoding the World is the kind of book you get when you give two guys $40 million, a world full of messy big problems, a genetics laboratory to play in, and a set of Borges' collected works. After looking through their lens, you'll never see the world the same.
Decolonised and Developmental Social Work: A Model from Nepal (Indigenous and Environmental Social Work)
by Raj YadavThis is the first book to cover existing debates on decolonising and developmental social work whilst equipping readers with the understanding of how to translate the idea of decolonisation of social work into practice. Using new empirical data and an extensive detail of social, cultural, and political dimensions of Nepal, the author proposes a new model of ‘decolonised and developmental social work’ that can be applicable to a wide range of countries and cultures. By using interviews with Nepali social workers, this text goes beyond mere theoretical approaches and uniquely positions itself in a way that embraces rigorous bottom-up, grounded theory method. It will also further ongoing debates on globalisation-localisation, universalisation-contextualisation, outsider-insider perspectives, neoliberal-rights and justice oriented social work, and above all, colonisation-decolonisation of social work knowledge and practice. It also promotes solidarity of, and the struggle for, progress for those in the margins of Western social work and development narrative through an emerging theory-praxis of decolonised and developmental social work. Decolonised and Developmental Social Work is essential reading for students, academics, and researchers of social work and development studies, as well as those striving for a decolonial worldview.
Decolonised and Developmental Social Work: A Model from Nepal (Indigenous and Environmental Social Work)
by Raj YadavThis is the first book to cover existing debates on decolonising and developmental social work whilst equipping readers with the understanding of how to translate the idea of decolonisation of social work into practice. Using new empirical data and an extensive detail of social, cultural, and political dimensions of Nepal, the author proposes a new model of ‘decolonised and developmental social work’ that can be applicable to a wide range of countries and cultures. By using interviews with Nepali social workers, this text goes beyond mere theoretical approaches and uniquely positions itself in a way that embraces rigorous bottom-up, grounded theory method. It will also further ongoing debates on globalisation-localisation, universalisation-contextualisation, outsider-insider perspectives, neoliberal-rights and justice oriented social work, and above all, colonisation-decolonisation of social work knowledge and practice. It also promotes solidarity of, and the struggle for, progress for those in the margins of Western social work and development narrative through an emerging theory-praxis of decolonised and developmental social work. Decolonised and Developmental Social Work is essential reading for students, academics, and researchers of social work and development studies, as well as those striving for a decolonial worldview.
Decolonising Public Health through Praxis: The Impact on Black Health in the UK
by Faye Bruce Ornette D. ClennonThis book provides an interdisciplinary analysis of UK African Diaspora health seekers and their sustained health inequalities in the health market. It translates their often-silenced voices into a decolonial praxis, where their experiences illuminate the hidden factors that have blighted change in health outcomes for these communities. The book excavates and breaks down the nature of these hidden factors, as historical patterns of behaviour that comprise whiteness over the longue durée. Using the lenses of decolonial and critical race studies, the book places whiteness within an ethical and moral framework in order to examine the hidden factors behind health inequalities. The book also looks at intersectionality and discusses whether it is actually fit for purpose as an analytical framework for discussing the health seeking behaviours of both Black men and Black women in relation to their unequal access to the health market.
Decolonization of Psychiatry in Jamaica: Madnificent Irations
by Frederick W. HicklingThis book traces the historical postcolonial journey of four generations of Jamaican psychiatrists challenging the European colonial ‘civilizing mission’ of psychiatric care. It details the process of deinstitutionizing patients with chronic mental illness using psychohistoriographic cultural therapy, by engaging them in creating sociodrama and poetry writing, not only to express and reverse the stigma contributing to their marginalized status, but also to reconnect them to a centuries-long history of oppression. The author thereby demonstrates that psychological decolonization requires a seminal understanding of the complex mental inter-relationship between slaves and slaveowners. Further, it is shown how the model analyzes the antipodal dialectic history of descendants of Africans enslaved in the New World by brutish British Imperialists suffering from the European psychosis of white supremacy. Drawing together a detailed description of the sociopoem Madnificent Irations, with an examination of Jamaica’s political and social history, and the author’s personal experience, this compelling work marks an important contribution to decolonial literature. It will be of particular interest to students and scholars of postcolonial studies, critical race theory, the history of psychology and community psychology.
Decolonizing Global Mental Health: The psychiatrization of the majority world (PDF)
by China MillsDecolonizing Global Mental Health is a book that maps a strange irony. The World Health Organization (WHO) and the Movement for Global Mental Health are calling to #65533;scale up#65533; access to psychological and psychiatric treatments globally, particularly within the global South. Simultaneously, in the global North, psychiatry and its often chemical treatments are coming under increased criticism (from both those who take the medication and those in the position to prescribe it). The book argues that it is imperative to explore what counts as evidence within Global Mental Health, and seeks to de-familiarize current #65533;Western#65533; conceptions of psychology and psychiatry using postcolonial theory. It leads us to wonder whether we should call for equality in global access to psychiatry, whether everyone should have the right to a psychotropic citizenship and whether mental health can, or should, be global. As such, it is ideal reading for undergraduate and postgraduate students, as well as researchers in the fields of critical psychology and psychiatry, social and health psychology, cultural studies, public health and social work.
Decolonizing Healthcare Innovation: Low-Cost Solutions from Low-Income Countries
by Matthew HarrisThis fascinating book offers a pathway for the NHS to adopt low-cost but effective innovations from areas of the world traditionally seen as beneficiaries rather than providers of help and support. In an era of increasing demand and dwindling resources, and where the COVID-19 pandemic has illustrated the structural limitations of the current system, the book provides examples of simple, frugal but high-quality alternatives to current practice. From orthopaedics to paediatrics, and mental health to plastic surgery, the book illustrates how low- and middle-income countries have found solutions to healthcare issues that are not only safe and clinically effective but also have the potential to save the NHS millions of pounds. Grounded in the contemporary debates of decolonization, it invites readers to question the culture and systems in global health that view low-income countries as solely passive recipients of aid. The volume will be essential reading for students and scholars across Public Health, Global Health, and Development Studies, as well as healthcare managers and policy makers in the UK and beyond.
Decolonizing Healthcare Innovation: Low-Cost Solutions from Low-Income Countries
by Matthew HarrisThis fascinating book offers a pathway for the NHS to adopt low-cost but effective innovations from areas of the world traditionally seen as beneficiaries rather than providers of help and support. In an era of increasing demand and dwindling resources, and where the COVID-19 pandemic has illustrated the structural limitations of the current system, the book provides examples of simple, frugal but high-quality alternatives to current practice. From orthopaedics to paediatrics, and mental health to plastic surgery, the book illustrates how low- and middle-income countries have found solutions to healthcare issues that are not only safe and clinically effective but also have the potential to save the NHS millions of pounds. Grounded in the contemporary debates of decolonization, it invites readers to question the culture and systems in global health that view low-income countries as solely passive recipients of aid. The volume will be essential reading for students and scholars across Public Health, Global Health, and Development Studies, as well as healthcare managers and policy makers in the UK and beyond.
Decolonizing International Health: India and Southeast Asia, 1930-65 (Cambridge Imperial and Post-Colonial Studies)
by S. AmrithThis book offers a history of international public health spanning the colonial and post-colonial eras. The volume focuses on India and the transnational networks connecting developments in India with Southeast Asia, and the wider world and contributes to debates on nationalism, internationalism and science in an age of decolonization.
Decompression — Decompression Sickness
by A. A. BühlmannThe Laboratory of Hyperbaric Physiology of the Medical Clinic of the University of Zurich came into existence in 1960 thanks to private initiative and a readiness to undertake risks; the success ful start was made possible with help from the French Navy and the United States Navy. A prerequisite for the development of the laboratory was also the benevolence of the authorities of the University of Zurich toward a research project from which scarcely any practical use could be expected for the land-locked country of Switzerland. The development of the laboratory and the systematic research were supported generously from 1964 by Shell Intemationale Petroleum Maatschappij of The Hague. The basic theme of the research was always the well-being and functional ability of the human being in an atmosphere of abnor mal pressure and or abnormal composition. Many connections became obvious with respiratory physiolo gy, circulatory physiology, and physiology at great heigts, and close contact with other special laboratories of the Medical Clin ic proved very valuable. With a relatively small number of steady collaborators it was possible to master an extensive experimental program. Special thanks are due to Mr. Benno Schenk, who as technical head was responsible for the exact performance of all the hyperbaric experiments.
Decompressive Techniques - E-Book
by Alaa Abd-ElsayedDecompressive Techniques, part of the Atlas of Interventional Pain Management series, is a concise, practical guide that provides clinicians with detailed, step-by-step guidance on how to perform decompressive procedures for treating patients with chronic lower back pain. This comprehensive, easy-to-follow guide offers expert coverage of how to deliver safe, accurate, and cost-effective pain relief to patients using all clinically useful imaging modalities, including ultrasound-guided techniques and fluoroscopy. With high-quality images and clear, authoritative guidance throughout, it shows exactly how to evaluate the causes of pain, identify the most promising stimulation technique, locate the site with precision, and deliver effective relief. Offers a comprehensive overview of the latest decompressive procedures. Features clinically relevant anatomic drawings and radiologic images that provide step-by-step instruction on techniques. Provides clear guidance on the risks and benefits, as well as indications and contraindications, for each procedure. Covers key topics such as percutaneous lumbar decompression, endoscopic discectomy, percutaneous discectomy, and more. Includes easy-to-follow, templated content on patient selection, preoperative prep, and post-operative care. Contains full-color line drawings, photographs, and ultrasound images that provide you with a firm grasp of the anatomy and equipment involved with each procedure. Highlights potential pitfalls for each technique and offers clinical pearls on how to avoid them.
Deconstructing Evidence-Based Practice
by Dawn Freshwater Gary RolfeThis innovative book strips the concept of evidence-based practice back to basics using deconstructive analysis, so that readers can move towards a clearer understanding of it. The practitioner is guided through a number of case studies in which the authors examine how the concept of evidence-based practice has been used in a variety of clinical settings. Divided into three parts, the book provides a deconstruction of key texts related to evidence based practice, weaving together contemporary themes in healthcare research.Deconstructing Evidence Based Practice is essential reading for nurses and other health practitioners who need to understand more about evidence-based practice and who want to learn methods of critical thinking that will be invaluable in judiciously informing their practice.
Deconstructing Evidence-Based Practice
by Dawn Freshwater Gary RolfeThis innovative book strips the concept of evidence-based practice back to basics using deconstructive analysis, so that readers can move towards a clearer understanding of it. The practitioner is guided through a number of case studies in which the authors examine how the concept of evidence-based practice has been used in a variety of clinical settings. Divided into three parts, the book provides a deconstruction of key texts related to evidence based practice, weaving together contemporary themes in healthcare research.Deconstructing Evidence Based Practice is essential reading for nurses and other health practitioners who need to understand more about evidence-based practice and who want to learn methods of critical thinking that will be invaluable in judiciously informing their practice.
Deconstructing Health Inequity: A Perceptual Control Theory Perspective
by Timothy A. Carey Sara J. Tai Robert GriffithsThis book offers a radically different perspective on the topic of health inequity. Carey, Tai, and Griffiths use Perceptual Control Theory (PCT) to deconstruct current approaches to understanding, investigating, and addressing problems of health inequity. In the book, the authors propose that health inequity is not a problem per se. Disrupted control, they argue, is the problem that needs to be addressed. From this perspective, research, policy, and health practices directed at addressing health inequity in isolation will offer only partial solutions to the problems created by disrupted control. Addressing problems of disrupted control directly, however, has the potential to entirely resolve issues that are created by health inequity. The authors have extensive clinical and research experience in a wide range of contexts, including: cross-cultural settings; rural, remote, and underserved communities; community mental health settings; prisons; schools; and psychiatric wards. Drawing on these diverse experiences, the authors describe how adopting a Perceptual Control Theory perspective might offer promising new directions for researchers and practitioners who have an interest in addressing issues of inequity and social justice. With a Foreword written by Professor Neil Gilbert this book will provide fresh insights for academics, practitioners, and policymakers in the fields of public health, psychology, social policy, and healthcare.
Deconstructing Scandinavia's "Achievement Generation": A Youth Mental Health Crisis?
by Ole Jacob MadsenIn this book, Professor Ole Jacob Madsen analyses the implications of Scandinavia's current concern for the mental health problems of adolescents, said to be struggling in the face of increasing demands for achievement and success. It critically examines our understanding of this so-called “achievement generation”, questioning whether today’s youth are really worse off than previous generations and how we have come to believe that this is so. The author’s wide-ranging investigation draws on a large body of research, as well as considering socio-political, historical and regional factors that might be affecting the resilience and mental health among young people. It also provides original psycholinguistic studies of popular media concepts associated with these issues including: “the achievement generation”, “pathological perfection” and “the good girl syndrome”. Deconstructing Scandinavia’s “Achievement Generation” presents an engaging contribution to key debates around therapeutic culture and society in the 21st century. It will appeal to students and scholars of critical and social psychology, sociology, anthropology, philosophy; as well as to those working in education, social work and mental health.
Deconstructing the Interview (Oxford Specialty Training: Revision Texts)
by Duncan HardingSucceeding at a clinical interview is a critical hurdle you will face throughout your training requiring you to demonstrate confidence, professionalism, and strong communication skills. Deconstructing the Interview takes a fresh approach to passing interviews, by examining the processes which underline successful interview performances. Instead of focusing on checklists of information, this book looks at factors for success in all interviews and helps you develop key strategies and skills that will enable success in any interview. Packed full of advice, practical tips, real-life anecdotes, and exercises; this book will provide you with skills to prepare for your interview and perform at your best. It also explores learning to cope with anxiety and how to benefit from failure so that you can perform even better next time. Ideal for health practitioners at all levels of training and all specialties, including medical or dental students, trainees, and consultants, nurses, and midwives; Deconstructing the Interview is full of practical advice to increase your confidence and improve your chances of success in any interview throughout your career.
Deconstructing the Interview (Oxford Specialty Training: Revision Texts)
by Duncan HardingSucceeding at a clinical interview is a critical hurdle you will face throughout your training requiring you to demonstrate confidence, professionalism, and strong communication skills. Deconstructing the Interview takes a fresh approach to passing interviews, by examining the processes which underline successful interview performances. Instead of focusing on checklists of information, this book looks at factors for success in all interviews and helps you develop key strategies and skills that will enable success in any interview. Packed full of advice, practical tips, real-life anecdotes, and exercises; this book will provide you with skills to prepare for your interview and perform at your best. It also explores learning to cope with anxiety and how to benefit from failure so that you can perform even better next time. Ideal for health practitioners at all levels of training and all specialties, including medical or dental students, trainees, and consultants, nurses, and midwives; Deconstructing the Interview is full of practical advice to increase your confidence and improve your chances of success in any interview throughout your career.
Deconstructing the OSCE: Strategies for OSCE Success
by Duncan Harding MRCPsychThe OSCE forms the practical part of educational and professional medical examinations and is often challenging and expensive. Deconstructing the OSCE takes a fresh approach to passing the OSCE, teaching readers how to tackle the examination in a new way. This book doesn't provide readers with checklists of information needed for specific OSCE stations; instead it will help you to develop key strategies and skills that will enable success in any OSCE regardless of specialty or level. Packed full of advice, practical tips, real-life examples, and exercises, this book will provide you with skills to prepare for effective OSCE study and strategies to overcome common hurdles and psychological baggage. It also explores how to overcome past failure in the OSCE by overhauling your previous study routines and suggesting new strategies for the road ahead. Ideal for trainee doctors sitting OSCEs at all levels, medical students, allied medical practitioners, nurses, and doctors from overseas; Deconstructing the OSCE is full of practical advice to increase candidates' confidence and improve the chance of success in any OSCE scenario.
Deconstructing the Welfare State: Managing Healthcare in the Age of Reform
by John Hassard Paula Hyde Leo McCann Edward GranterWho are NHS middle managers? What do they do, and why and how do they do it’? This book explores the daily realities of working life for middle managers in the UK’s National Health Service during a time of radical change and disruption to the entire edifice of publicly-funded healthcare. It is an empirical critique of the movement towards a healthcare model based around HMO-type providers such as Kaiser Permanente and United Health. Although this model is well-known internationally, many believe it to be financially and ethically questionable, and often far from 'best practice' when it comes to patient care. Drawing on immersive ethnographic research based on four case studies – an Acute Hospital Trust, an Ambulance Trust, a Mental Health Trust, and a Primary Care Trust – this book provides an in-depth critical appraisal of the everyday experiences of a range of managers working in the NHS. It describes exactly what NHS managers do and explains how their roles are changing and the types of challenges they face. The analysis explains how many NHS junior and middle managers are themselves clinicians to some extent, with hybrid roles as simultaneously nurse and manager, midwife and manager, or paramedic and manager. While commonly working in ‘back office’ functions, NHS middle managers are also just as likely to be working very close to or actually on the front lines of patient care. Despite the problems they regularly face from organizational restructuring, cost control and demands for accountability, the authors demonstrate that NHS managers – in their various guises – play critical, yet undervalued, institutional roles. Depicting the darker sides of organizational change, this text is a sociological exploration of the daily struggle for work dignity of a complex, widely denigrated, and largely misunderstood group of public servants trying to do their best under extremely trying circumstances. It is essential reading for academics, students, and practitioners interested in health management and policy, organisational change, public sector management, and the NHS more broadly.
Deconstructing the Welfare State: Managing Healthcare in the Age of Reform
by John Hassard Paula Hyde Leo McCann Edward GranterWho are NHS middle managers? What do they do, and why and how do they do it’? This book explores the daily realities of working life for middle managers in the UK’s National Health Service during a time of radical change and disruption to the entire edifice of publicly-funded healthcare. It is an empirical critique of the movement towards a healthcare model based around HMO-type providers such as Kaiser Permanente and United Health. Although this model is well-known internationally, many believe it to be financially and ethically questionable, and often far from 'best practice' when it comes to patient care. Drawing on immersive ethnographic research based on four case studies – an Acute Hospital Trust, an Ambulance Trust, a Mental Health Trust, and a Primary Care Trust – this book provides an in-depth critical appraisal of the everyday experiences of a range of managers working in the NHS. It describes exactly what NHS managers do and explains how their roles are changing and the types of challenges they face. The analysis explains how many NHS junior and middle managers are themselves clinicians to some extent, with hybrid roles as simultaneously nurse and manager, midwife and manager, or paramedic and manager. While commonly working in ‘back office’ functions, NHS middle managers are also just as likely to be working very close to or actually on the front lines of patient care. Despite the problems they regularly face from organizational restructuring, cost control and demands for accountability, the authors demonstrate that NHS managers – in their various guises – play critical, yet undervalued, institutional roles. Depicting the darker sides of organizational change, this text is a sociological exploration of the daily struggle for work dignity of a complex, widely denigrated, and largely misunderstood group of public servants trying to do their best under extremely trying circumstances. It is essential reading for academics, students, and practitioners interested in health management and policy, organisational change, public sector management, and the NHS more broadly.
Decontamination of Pesticide Residues in the Environment: Atlantic City Meetings of the American Chemical Society September 1968 (Residue Reviews/Rückstandsberichte #29)
by Francis A. GuntherThat residues of pesticide and other "foreign" chemicals in food stuffs are of concern to everyone everywhere is amply attested by the reception accorded previous volumes of "Residue Reviews" and by the gratifying enthusiasm, sincerity, and efforts shown by all the in dividuals from whom manuscripts have been solicited. Despite much propaganda to the contrary, there can never be any serious question that pest-control chemicals and food-additive chemicals are essential to adequate food production, manufacture, marketing, and storage, yet without continuing surveillance and intelligent control some of those that persist in our foodstuffs could at times conceivably endanger the public health. Ensuring safety-in-use of these many chemicals is a dynamic challenge, for established ones are continually being dis placed by newly developed ones more acceptable to food tech nologists, pharmacologists, toxicologists, and changing pest-control requirements in progressive food-producing economies. These matters are of genuine concern to increasing numbers of governmental agencies and legislative bodies around the world, for some of these chemicals have resulted in a few mishaps from improper use. Adequate safety-in-use evaluations of any of these chemicals per sisting into our foodstuffs are not simple matters, and they incorporate the considered judgments of many individuals highly trained in a variety of complex biological, chemical, food technological, medical, pharmacological, and toxicological disciplines.
The Decubitus Ulcer in Clinical Practice
by Lawrence Charles Parish Joseph A. Witkowski John Thorne CrisseyWith patients now surviving trauma, neurological diseases, and the geriatric state for longer periods, dermatologists are increasingly being called on to manage these often devastating cutaneous defects. Unrealistic goals regarding prevention and wound healing have compounded the problem, while patient awareness, government intervention, and legal entanglements make an understanding of the diagnosis and management of this dermatologic entity mandatory. This volume addresses how to both recognise and manage the condition. Beginning with the background of the disease, the book goes on to discuss the clinical features and provides a comprehensive overview of general and specific therapeutic strategies.
Deeno's Dream Journeys in the Big Blue Bubble: A Relaxation Programme to Help Children Manage their Emotions
by Gerry Turley Julia LangensiepenDeeno's Dream Journeys in the Big Blue Bubble is a fun and easy-to-use guide to a special relaxation technique for children. Adapted from the system of Autogenics, the six-week programme uses positive affirmations and guided imagery to help children manage their emotions, let go of anxiety and feel calm and confident. Each week, the child is given a new set of 'magic words': a relaxation tool they can draw upon whenever they feel stressed or anxious. An illustrated story based around these words, where the child is asked to imagine they are going on an adventure in a big blue bubble with Deeno the Dinosaur, draws the child into a safe and magical world and guides their minds and bodies into a state of deep, calming relaxation. Suggestions for follow-up practice and creative activities based around that week's words accompany each session, and encourage children to tap into their own imaginations. Separate introductions for parents, teachers and other professionals provide advice on how best to use the technique, whether at home, at school, or elsewhere. There is also a children's introduction, which introduces Deeno and explains the technique in accessible terms. Accessible and engaging, Deeno's Dream Journeys in the Big Blue Bubble is an ideal tool for helping children develop effective relaxation skills in a fun and imaginative way.
Deeno's Dream Journeys in the Big Blue Bubble: A Relaxation Programme to Help Children Manage their Emotions (PDF)
by Gerry Turley Julia LangensiepenDeeno's Dream Journeys in the Big Blue Bubble is a fun and easy-to-use guide to a special relaxation technique for children. Adapted from the system of Autogenics, the six-week programme uses positive affirmations and guided imagery to help children manage their emotions, let go of anxiety and feel calm and confident. Each week, the child is given a new set of 'magic words': a relaxation tool they can draw upon whenever they feel stressed or anxious. An illustrated story based around these words, where the child is asked to imagine they are going on an adventure in a big blue bubble with Deeno the Dinosaur, draws the child into a safe and magical world and guides their minds and bodies into a state of deep, calming relaxation. Suggestions for follow-up practice and creative activities based around that week's words accompany each session, and encourage children to tap into their own imaginations. Separate introductions for parents, teachers and other professionals provide advice on how best to use the technique, whether at home, at school, or elsewhere. There is also a children's introduction, which introduces Deeno and explains the technique in accessible terms. Accessible and engaging, Deeno's Dream Journeys in the Big Blue Bubble is an ideal tool for helping children develop effective relaxation skills in a fun and imaginative way.