Browse Results

Select your format based upon: 1) how you want to read your book, and 2) compatibility with your reading tool. To learn more about using Bookshare with your device, visit the Help Center.

Here is an overview of the specialized formats that Bookshare offers its members with links that go to the Help Center for more information.

• Bookshare Web Reader - A customized reading tool for Bookshare members offering all the features of DAISY with a single click of the "Read Now" link.
• DAISY (Digital Accessible Information System) - A digital book file format. DAISY books from Bookshare are DAISY 3.0 text files that work with just about every type of access technology that reads text. Books that contain images will have the download option of ‘DAISY Text with Images’.
• BRF (Braille Refreshable Format) - Digital Braille for use with refreshable Braille devices and Braille embossers.
• MP3 (MPEG audio layer 3) - Provides audio only with no text. These books are created with a text-to-speech engine and spoken by Kendra, a high quality synthetic voice from Ivona. Any device that supports MP3 playback is compatible.
• DAISY Audio - Similar to the DAISY option above; however, this option uses MP3 files created with our text-to-speech engine that utilizes Ivonas Kendra voice. This format will work with Daisy Audio compatible players such as Victor Reader Stream and Read2Go.
• EPUB - A standard e-book format that can be read on many tools, such as iBooks, Readium or others.
• Word - Accessible Word output, which can be unzipped and opened in any tool that allows .docx files

Defeating Autism: A Damaging Delusion

Autism: disease, disorder or difference? What causes autism – genes or environment? Can biomedical treatments cure autism, and are they safe? An increased public awareness of autism has resulted in a rising trend of diagnoses, creating the impression of an ‘epidemic’. Many parents of children newly diagnosed with autism have been impressed by plausible theories blaming vaccines and other environmental causes. Many have also been captivated by claims that ‘biomedical’ treatments – including special diets and supplements, detoxification and medications – can achieve dramatic results. In Defeating Autism, Michael Fitzpatrick, a family doctor and father of a son with autism, questions the scientific basis of environmental explanations of autism and exposes the incoherence of unorthodox ‘biomedical’ theories and therapies. This book reveals that these therapies are far from pioneering interventions and they remain unsubstantiated by scientific authorities. Campaigns promising to ‘defeat or cure autism now’ have attracted much support among parents struggling with their difficult children. But the crusade against autism risks dehumanising and stigmatising those who are identified as autistic and their families. This compelling book is essential reading for students and professionals working in the field of autism, as well as academics concerned with the public understanding of science and the treatment of scientific and medical controversies in the media.

Defeating Autism: A Damaging Delusion

Autism: disease, disorder or difference? What causes autism – genes or environment? Can biomedical treatments cure autism, and are they safe? An increased public awareness of autism has resulted in a rising trend of diagnoses, creating the impression of an ‘epidemic’. Many parents of children newly diagnosed with autism have been impressed by plausible theories blaming vaccines and other environmental causes. Many have also been captivated by claims that ‘biomedical’ treatments – including special diets and supplements, detoxification and medications – can achieve dramatic results. In Defeating Autism, Michael Fitzpatrick, a family doctor and father of a son with autism, questions the scientific basis of environmental explanations of autism and exposes the incoherence of unorthodox ‘biomedical’ theories and therapies. This book reveals that these therapies are far from pioneering interventions and they remain unsubstantiated by scientific authorities. Campaigns promising to ‘defeat or cure autism now’ have attracted much support among parents struggling with their difficult children. But the crusade against autism risks dehumanising and stigmatising those who are identified as autistic and their families. This compelling book is essential reading for students and professionals working in the field of autism, as well as academics concerned with the public understanding of science and the treatment of scientific and medical controversies in the media.

Defeating Pain: The War Against a Silent Epidemic (pdf)

Defective Housing and the Growth of Children (Routledge Revivals)

After World War I, housing was one of many pressing issues facing the country with multiple families often crowded in together in inadequate housing. This had a dramatic impact on health with increasing problems such as tuberculosis and malnutrition. Originally published in 1919, this study aimed to identify the ways in which defective housing impacted on health in the family with a particular focus on rickets in children in the East end of London and the developmental issues resulting from it. This title will be of interest to students of Medical History and Health and Social Care.

Defective Housing and the Growth of Children (Routledge Revivals)

After World War I, housing was one of many pressing issues facing the country with multiple families often crowded in together in inadequate housing. This had a dramatic impact on health with increasing problems such as tuberculosis and malnutrition. Originally published in 1919, this study aimed to identify the ways in which defective housing impacted on health in the family with a particular focus on rickets in children in the East end of London and the developmental issues resulting from it. This title will be of interest to students of Medical History and Health and Social Care.

Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy (Resistance to Targeted Anti-Cancer Therapeutics #9)

This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.

Defects of Secretion in Cystic Fibrosis (Advances In Experimental Medicine And Biology Ser. #Vol. 558)

Defects in Secretion of Cystic Fibrosis presents an overview on current research from leading experts in North America and Europe. This update on cystic fibrosis provides in depth original work as well as review material on many of the relevant physiological and molecular topics in the field. Subjects covered include the interplay of the various epithelial ion channels, the underlying intracellular signal transduction, mucus secretion, and novel approaches to develop drugs against cystic fibrosis. This book brings together physicians, physiologists, and other scientists involved in basic research, from molecular biology to drug design and introduces novel investigative and therapeutic aspects of secretion disorders relevant in cystic fibrosis and related diseases. This book will be of interest to Molecular biologists, physiologists, scientists working in pharmaceutical research and drug developement, physicians and researchers in Cystic fibrosis and related diseases.

Defence Against Bioterrorism: Methods for Prevention and Control (NATO Science for Peace and Security Series A: Chemistry and Biology)

This volume is based on a multidisciplinary approach towards biological and chemical threats that can, and have been previously used in bioterrorism attacks around the globe. Current knowledge and evidence-based principles from the fields of synthetic biology, microbiology, plant biology, chemistry, food science, forensics, tactics, infective medicine, psychology and others are compiled to address numerous aspects and the complexity of bioterrorism attacks. The main focus is on biological threats, especially in the context of synthetic biology and its emerging findings that can be observed as possible threat and tool. The book examines microorganisms and their possible use in forensics, i.e. as possible detection tool that could enable fast and precise detection of possible treats. A number of plant derived components are also discussed as possible agents in bioterrorism attacks, and in relation to infectious disease pathology. Another integral part is food safety, especially in terms of large food supply chains, like airline caterings, institutionalized kitchens etc. Food can be observed as a possible mean of delivery of various agents (biological and chemical) for bioterrorism attacks. Steps on how to recognize specific critical points in a food supply chain, along with proposed corrective activities are discussed.Examples from around the globe, along with the methodological approach on how to differentiate bioterrorism attacks from other epidemics are provided. However, epidemics are also discussed in the context of migrations, with the special emphasis on the current refugee migrations that affect not only Europe, but also the United States. The book will be of interest to experts from various fields of science as well as professionals working in the field. The book encompasses examples and tools developed for easier, more specific, and faster detection of possible bioterrorism treats, along with proposed actions for some aspects of a bioterrorism attack.

Defending Life: The Nature of Host-Parasite Relations

Defending Life discusses the relationship between hosts and parasites. It contains detailed descriptions of the immune system and the microbial world as well as methodological and conceptual clarifications. Its emphasis on analytical abstractions, coherent patterns and generative mechanisms makes possible the distinction between genuine causality and coincidental associations and increases the understanding of why we observe what we observe.

Defending Standardized Testing

The education reform movement of the past two decades has focused on raising academic standards. Some standards advocates attach a testing mechanism to gauge the extent to which high standards are actually accomplished, whereas some critics accuse the push for standards and testing of impeding reform and perpetuating inequality. At the same time, the testing profession has produced advances in the format, accuracy, dependability, and utility of tests. Never before has obtaining such an abundance of accurate and useful information about student learning been possible. Meanwhile, the American public remains steadfast in support of testing to measure student performance and monitor the performance of educational systems.Many educational testing experts who acknowledge the benefits of testing also believe that those benefits have been insufficiently articulated. Although much has been written on standardized testing policy, most of the material has been written by opponents. The contributing authors of this volume are both accomplished researchers and practitioners who are respected and admired worldwide. They bring to the project an abundance of experience working with standardized tests.The goal of Defending Standardized Testing is to:*describe current standardized testing policies and strategies;*explain many of the common criticisms of standardized testing;*document the public support for, and the realized benefits of, standardized testing;*acknowledge the limitations of, and suggest improvements to, testing practices;*provide guidance for structuring and administering large-scale testing programs in light of public preferences and the "No Child Left Behind Act" requirements; and*present a defense of standardized testing and a vision for its future.Defending Standardized Testing minimizes the use of technical jargon so as to appeal to all who have a stake in American educational reform.

Defending Standardized Testing

The education reform movement of the past two decades has focused on raising academic standards. Some standards advocates attach a testing mechanism to gauge the extent to which high standards are actually accomplished, whereas some critics accuse the push for standards and testing of impeding reform and perpetuating inequality. At the same time, the testing profession has produced advances in the format, accuracy, dependability, and utility of tests. Never before has obtaining such an abundance of accurate and useful information about student learning been possible. Meanwhile, the American public remains steadfast in support of testing to measure student performance and monitor the performance of educational systems.Many educational testing experts who acknowledge the benefits of testing also believe that those benefits have been insufficiently articulated. Although much has been written on standardized testing policy, most of the material has been written by opponents. The contributing authors of this volume are both accomplished researchers and practitioners who are respected and admired worldwide. They bring to the project an abundance of experience working with standardized tests.The goal of Defending Standardized Testing is to:*describe current standardized testing policies and strategies;*explain many of the common criticisms of standardized testing;*document the public support for, and the realized benefits of, standardized testing;*acknowledge the limitations of, and suggest improvements to, testing practices;*provide guidance for structuring and administering large-scale testing programs in light of public preferences and the "No Child Left Behind Act" requirements; and*present a defense of standardized testing and a vision for its future.Defending Standardized Testing minimizes the use of technical jargon so as to appeal to all who have a stake in American educational reform.

Defending the Genetic Supermarket: The Law and Ethics of Selecting the Next Generation (Biomedical Law and Ethics Library)

The controversial topic of the technology of Pre-implantation Genetic Diagnosis, and the muddled approach to this subject adopted by the UK Parliament, is explored in detail in this volume. The author takes the viewpoint that the HFEA has taken insufficient notice to date of certain core ethical principles and makes the case for a much more ethically consistent and humane system than has been managed so far. Arguing that many of the fears and objections levied against Robert Nozick’s notion of the ‘Genetic Supermarket’ by disability activists, christian bioethicists and radical feminists, amongst others, are internally inconsistent, philosophically unsound or merely highly improbable, the author considers a number of individual policy decisions of the HFEA and addresses such questions as: Can a case be made out for state involvement in such decisions? Who stands to be harmed by a supermarket model? Are any ethical principles or societal interests threatened by it? This book is an essential resource for law students of all levels and professionals working within or interested in medical and healthcare law and medical genetics.

Defending the Genetic Supermarket: The Law and Ethics of Selecting the Next Generation (Biomedical Law and Ethics Library)

The controversial topic of the technology of Pre-implantation Genetic Diagnosis, and the muddled approach to this subject adopted by the UK Parliament, is explored in detail in this volume. The author takes the viewpoint that the HFEA has taken insufficient notice to date of certain core ethical principles and makes the case for a much more ethically consistent and humane system than has been managed so far. Arguing that many of the fears and objections levied against Robert Nozick’s notion of the ‘Genetic Supermarket’ by disability activists, christian bioethicists and radical feminists, amongst others, are internally inconsistent, philosophically unsound or merely highly improbable, the author considers a number of individual policy decisions of the HFEA and addresses such questions as: Can a case be made out for state involvement in such decisions? Who stands to be harmed by a supermarket model? Are any ethical principles or societal interests threatened by it? This book is an essential resource for law students of all levels and professionals working within or interested in medical and healthcare law and medical genetics.

Defense Against Biological Attacks: Volume I

This first volume of a two-volume set is divided into two themed parts. The first part describes general aspects, such as the historical view on the topic, the role of information distribution and preparedness of health-care systems and preparedness in emergency cases. Part two describes and discusseses in detail the pathogens and toxins that are potentially used for biological attacks. As such, the book is a valuable resource for faculties engaged in molecular biology, genetic engineering, neurology, biodefense, biosafety & biosecurity, virology, and infectious disease programs, as well as professional medical research organizations.

Defense Against Biological Attacks: Volume II

This second volume of a two-volume set focuses on specific pathogens and their mechanisms of pathogenesis as well as diagnostics, therapeutics and various strategies in the event of biological attacks. This multidisciplinary book appeals to readers from various fields, including biodefense, biosafety & biosecurity, virology, neurology, molecular biology and genetic engineering, as well as infectious disease specialists. Further, the work is of interest to basic science and applied science research scholars and experts working in the area of high-consequence or select agent virology.

Defense against Bioterror: Proceedings of the NATO Advanced Research Workshop on Defense against Bioterror: Detection Technologies, Implementation Strategies and Commercial Opportunities, held in Madrid, Spain from 8 to 11 April 2004 (NATO Science for Peace and Security Series)

This is a critical assessment of breakthrough biosensor technologies that will allow for the rapid identification of biological threat agents in the environment and human population. The book provides a comprehensive overview of the current state of biological weapons threat, and reviews biosensor technologies including detection platforms, networked alarm-type biodetector systems, implementation strategies, electro-optical and electrochemical biosensors.

Defense of Mucosal Surfaces: Pathogenesis, Immunity and Vaccines (Current Topics in Microbiology and Immunology #236)

Mucosal immunity encompasses a broad field of research that includes areas of epithelial cell and molecular biology, molecular and cellular immunology, microbiology, virology, and vaccinology. This volume presents up to date and concise discussions of concepts as well as recent advances. It provides an overview of the components of the mucosal immune system, and the basic science relevant to mucosal vaccination. The authors assess current research in critical areas including: Organization of mucosal lymphoid tissue; antigen sampling and presentation in mucosal tissues; mucosalimmune responses and tolerance; immune effectors at mucosal sites; microbial-host interactions at mucosal sites; mucosal vaccines and adjuvants. This multi-disciplinary effort will be a valuable resource for researchers, clinicians and students who need a clear understanding of concepts and a guide to the wide-ranging literature in this very active research area.

Defining Physiology: Cardiovascular, Respiratory and Renal Physiology

This book will provide the reader with an overview of the essential meanings of key words in the physiology of various organ systems. This book is linked to a Question and Answer book on these organ systems that was published previously by Springer and will focus on cardiovascular, pulmonary and renal physiology. Each physiology system will be organized in to five different sections, covering the main areas of interest and each section will contain at least ten clear definitions of the main topics in this area. This book will present an easy reference guide for those just starting out in the area of physiology and for those who are interested in clear and succinct definitions of key terms.

Defining Physiology: Neurophysiology and Gastrointestinal Systems

This second volume of Defining Physiology: Principles, Themes, Concepts. continues on the same format as the first.In this new release, a selection of 44 essential topics in each major organ system is defined, then major themes, concept and principles surrounding these words in their physiologic scenarios are elaborated. For each keyword, a question is posed at the end of the text to test for a better understanding of the associated physiology of nervous and gastrointestinal systems.This book presents an easy reference guide for those just starting out in the area of physiology and for those who are interested in clear and succinct definitions of key terms.

Defining Prevention Science (Advances in Prevention Science)

Whoever coined the adage "an ounce of prevention is worth a pound of cure" could not have known how important this adage would become. The challenge of altering the health trajectories of poor lifestyle decisions for such behaviors as smoking, drinking and using illicit drugs, violence, dropping out of school, engagement in risky sexual behaviors and crime through prevention research has led to a new discipline, prevention science.Defining Prevention Science covers this emerging field of science: its goals, its conceptual and theoretical foundations, its methods and especially its utility. Not content to simply differentiate the field from its close allies: epidemiology, psychology, neuroscience, sociology, economics, the text explains how these many disciplines enhance each other at both research and intervention levels and how prevention science draws on these biological, behavioral and social sciences to create an innovative knowledge base that has provided cost-effective, evidence-based prevention interventions and policies. To this end, familiar developmental benchmarks are recast in prevention/health promotion context, from the crucial importance of adolescence in encountering and deterring high-risk behaviors to the risks and resiliencies of single-mother families. An international group of contributors offers current findings, up-to-date methods for effective evidence-based interventions and improvements in research technologies in these key areas:Physical, cognitive and emotional vulnerability across the life course.The roles of developmental influences in prevention.Intervention development, delivery and implementation.Bringing the intervention approach to research design.New directions in analytic methods.Cost analysis and policy implications.Advances in Prevention Science: Defining Prevention Science aims to inspire further refinements in the field and encourage communication among researchers in its own and related disciplines, including public health, epidemiology, psychology, and criminology. This is the first volume in the series, Advances in Prevention Science, that provides the framework for other volume that will focus on such issues as: Prevention Science in School Settings: Complex Relationships and Processes; Preventing Crime and Violence and The Prevention of Substance Use.

The Definitive Guide to Emergency Department Operational Improvement: Employing Lean Principles with Current ED Best Practices to Create the “No Wait” Department, Second Edition

This revised and updated book explores the academics behind managing the complex service environment that is the Emergency Department (ED) by combining applied management science and practical experiences to create a model of how to improve operations. This book offers a presentation of Lean tools used in the ED along with basic and advanced flow principles. It then shows how these concepts are applied and why they work, supported by case studies in which Lean principles were used to transform an underperforming ED into a world-class operation. After reviewing best practices, the authors explain how to achieve excellence by discussing the elements of creating a culture of change.

The Definitive Guide to Emergency Department Operational Improvement: Employing Lean Principles with Current ED Best Practices to Create the “No Wait” Department, Second Edition

This revised and updated book explores the academics behind managing the complex service environment that is the Emergency Department (ED) by combining applied management science and practical experiences to create a model of how to improve operations. This book offers a presentation of Lean tools used in the ED along with basic and advanced flow principles. It then shows how these concepts are applied and why they work, supported by case studies in which Lean principles were used to transform an underperforming ED into a world-class operation. After reviewing best practices, the authors explain how to achieve excellence by discussing the elements of creating a culture of change.

The Definitive Guide to the OSCE: The Objective Structured Clinical Examination as a performance assessment. (. Net Developers Ser.)

The new book is the definitive text on the Objective Structured Clinical Examination (OSCE), providing an easily accessible account of the breadth and depth of experience gained worldwide from its use in a wide range of contexts and in different phases of education. The lessons learned from these diverse experiences are included throughout the text. Used globally in all phases of education in the different healthcare professions, the OSCE was first described by the lead author, Harden, in 1975 and it is now the gold standard for performance assessment. The new book is the definitive text on the Objective Structured Clinical Examination (OSCE), providing an easily accessible account of the breadth and depth of experience gained worldwide from its use in a wide range of contexts and in different phases of education. The lessons learned from these diverse experiences are included throughout the text. Used globally in all phases of education in the different healthcare professions, the OSCE was first described by the lead author, Harden, in 1975 and it is now the gold standard for performance assessment.

Deformable Models: Theory and Biomaterial Applications (Topics in Biomedical Engineering. International Book Series)

This book covers the complete spectrum of deformable models, its evolution as an imagery field and its use in many biomedical engineering and clinical application disciplines. The book focuses on the core image processing techniques, theory and biomaterials useful to research and industry. Contributors are all pioneers in the field.

Deformable Models: Biomedical and Clinical Applications (Topics in Biomedical Engineering. International Book Series)

This book covers the complete spectrum of deformable models, its evolution as an imagery field and its use in many biomedical engineering and clinical application disciplines. It includes level sets, PDEs, curve and surface evolution and their applications in biomedical fields covering both static and motion imagery.