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Desperate Remedies: Psychiatry and the Mysteries of Mental Illness

'A riveting chronicle of faulty science, false promises, arrogance, greed, and shocking disregard for the wellbeing of patients suffering from mental disorders. An eloquent, meticulously documented, clear-eyed call for change' Dirk WittenbornIn this masterful work, Andrew Scull, one of the most provocative thinkers writing about psychiatry, sheds light on its troubled historyFor more than two hundred years, disturbances of reason, cognition and emotion - the sort of things that were once called 'madness' - have been described and treated by the medical profession. Mental illness, it is said, is an illness like any other - a disorder that can treated by doctors, whose suffering can be eased, and from which patients can return. And yet serious mental illness remains a profound mystery that is in some ways no closer to being solved than it was at the start of the twentieth century.In this clear-sighted and provocative exploration of psychiatry, acclaimed sociologist Andrew Scull traces the history of its attempts to understand and mitigate mental illness: from the age of the asylum and surgical and chemical interventions, through the rise and fall of Freud and the talking cure, and on to our own time of drug companies and antidepressants. Through it all, Scull argues, the often vain and rash attempts to come to terms with the enigma of mental disorder have frequently resulted in dire consequences for the patient.Deeply researched and lucidly conveyed, Desperate Remedies masterfully illustrates the assumptions and theory behind the therapy, providing a definitive new account of psychiatry's and society's battle with mental illness.

Desperately Seeking Solutions: Rationing Health Care

Following the Governments health reforms in 1991 rationing has been put firmly on the agenda. This book identifies and clarifies the numerous political and ethical issues surrounding rationing in healthcare. Drawing upon international examples it offers a critical overview of the approaches to rationing and makes practical proposals for its management.Desperately Seeking Solutions challenges the assumption that all health services are inherently subject to rationing as demand invariably outstrips supply and examines this within a comparative framework. The author critically evaluates the extent to which rationing has always existed and should exist within the NHS, although until recently it operated on an implicit rather than explicit basis and was bound up with clinical judgements rather than purely financial considerations. The author questions whether calls for explicit rationing are actually desirable and potentially feasible.

Desperately Seeking Solutions: Rationing Health Care

Following the Governments health reforms in 1991 rationing has been put firmly on the agenda. This book identifies and clarifies the numerous political and ethical issues surrounding rationing in healthcare. Drawing upon international examples it offers a critical overview of the approaches to rationing and makes practical proposals for its management.Desperately Seeking Solutions challenges the assumption that all health services are inherently subject to rationing as demand invariably outstrips supply and examines this within a comparative framework. The author critically evaluates the extent to which rationing has always existed and should exist within the NHS, although until recently it operated on an implicit rather than explicit basis and was bound up with clinical judgements rather than purely financial considerations. The author questions whether calls for explicit rationing are actually desirable and potentially feasible.

Destigmatisation of People Living with HIV/AIDS in China (A Sociological View of AIDS)

After reviewing related theories on stigmatisation of people living with HIV/AIDS (PLWHA), this book applies social exclusion theory, actor theory and stigma theory to the study of social mechanisms of stigmatisation of PLWHA in China to show the influence and mechanism of stigmatisation on them, and tries to construct the policy framework to tackle stigmatisation from the perspective of welfare pluralism. Qualitative analysis was used and data was obtained during the field interview. Thirty PLWHA and seventeen healthy people (non-infected people and staff of ASO Service Organizations) were selected by using random sampling and snowball sampling for semi-structured depth interviews. The research examines the treatments and living conditions of those PLWHA, aiming to explore the influence of HIV on them in education, employment, medical care, economy, welfare and social relations. The book is intended for graduate students, researchers interested in this field and relevant policymakers.

Destination Unknown: B2 (Collins Agatha Christie Elt Readers Ser.)

A young woman with nothing to live for is persuaded to embark on a suicide mission to find a missing scientist…

Destroying Sanctuary: The Crisis in Human Service Delivery Systems

For the last thirty years, the nation's mental health and social service systems have been under relentless assault, with dramatically rising costs and the fragmentation of service delivery rendering them incapable of ensuring the safety, security, and recovery of their clients. The resulting organizational trauma both mirrors and magnifies the trauma-related problems their clients seek relief from. Just as the lives of people exposed to chronic trauma and abuse become organized around the traumatic experience, so too have our social service systems become organized around the recurrent stress of trying to do more under greater pressure: they become crisis-oriented, authoritarian, disempowered, and demoralized, often living in the present moment, haunted by the past, and unable to plan for the future. Complex interactions among traumatized clients, stressed staff, pressured organizations, and a social and economic climate that is often hostile to recovery efforts recreate the very experiences that have proven so toxic to clients in the first place. Healing is possible for these clients if they enter helping, protective environments, yet toxic stress has destroyed the sanctuary that our systems are designed to provide. This thoughtful, impassioned critique of business as usual begins to outline a vision for transforming our mental health and social service systems. Linking trauma theory to organizational function, Destroying Sanctuary provides a framework for creating truly trauma-informed services. The organizational change method that has become known as the Sanctuary Model lays the groundwork for establishing safe havens for individual and organizational recovery. The goals are practical: improve clinical outcomes, increase staff satisfaction and health, increase leadership competence, and develop a technology for creating and sustaining healthier systems. Only in this way can our mental health and social service systems become empowered to make a more effective contribution to the overall health of the nation. Destroying Sanctuary is a stirring call for reform and recovery, required reading for anyone concerned with removing the formidable barriers to mental health and social services, from clinicians and administrators to consumer advocates.

Destroying Sanctuary: The Crisis in Human Service Delivery Systems

For the last thirty years, the nation's mental health and social service systems have been under relentless assault, with dramatically rising costs and the fragmentation of service delivery rendering them incapable of ensuring the safety, security, and recovery of their clients. The resulting organizational trauma both mirrors and magnifies the trauma-related problems their clients seek relief from. Just as the lives of people exposed to chronic trauma and abuse become organized around the traumatic experience, so too have our social service systems become organized around the recurrent stress of trying to do more under greater pressure: they become crisis-oriented, authoritarian, disempowered, and demoralized, often living in the present moment, haunted by the past, and unable to plan for the future. Complex interactions among traumatized clients, stressed staff, pressured organizations, and a social and economic climate that is often hostile to recovery efforts recreate the very experiences that have proven so toxic to clients in the first place. Healing is possible for these clients if they enter helping, protective environments, yet toxic stress has destroyed the sanctuary that our systems are designed to provide. This thoughtful, impassioned critique of business as usual begins to outline a vision for transforming our mental health and social service systems. Linking trauma theory to organizational function, Destroying Sanctuary provides a framework for creating truly trauma-informed services. The organizational change method that has become known as the Sanctuary Model lays the groundwork for establishing safe havens for individual and organizational recovery. The goals are practical: improve clinical outcomes, increase staff satisfaction and health, increase leadership competence, and develop a technology for creating and sustaining healthier systems. Only in this way can our mental health and social service systems become empowered to make a more effective contribution to the overall health of the nation. Destroying Sanctuary is a stirring call for reform and recovery, required reading for anyone concerned with removing the formidable barriers to mental health and social services, from clinicians and administrators to consumer advocates.

Detecting Malingering and Deception: Forensic Distortion Analysis (FDA-5) (Pacific Institute Series on Forensic Psychology)

Detecting Malingering and Deception: Forensic Distortion Analysis (FDA-5), Third Edition maintains the tradition of the prior two editions, following the Forensic Distortion Analysis (FDA) model. Fully updated since the last edition nearly 20 years ago, the book continues to serve as comprehensive volume on deception and distortion in forensic, clinical and several specialized contexts. As with the previous editions, the book presents a model of deception intended to be utilized and applied by the qualified evaluator. The proposed model covers targets of the faker, response styles show, and methods to detect the deception. The goal is to summarize the historical and latest information on distortion detection, to present guidelines for detecting deception that include variable accuracy rates based on different detection techniques, and to stimulate further research of effective methods of deception detection. Recommendations and guidelines for the practicing clinician are offered throughout the book, including real-world cases to inform and enlighten, particularly in unique cases or those in which the certain outcomes are unexpected. Key Features: Outlines the role of the forensic professional in applying and integrating methods assessment in deception and distortion Provides base-rates for deception-related behavior and events, especially useful in report writing or courtroom testimony as an expert witness Presents the latest advances in methodology and technology to assist in the search for ground truth in applied settings and situations Applies forensic distortion analysis to evaluate the deception-related findings and statements of other professionals involved in a particular case New coverage includes sections and chapters on deception analysis for collectivities, including media groups, contemporary politics, cross-national corporations, conflict, and terrorism Detecting Malingering and Deception incorporates the latest research, providing practical application to utilize information and evaluative methods as they pertain to deception-related settings and situations. Sample reports and extensive graphs, tables, charts, and histograms are provided, and every chapter has been updated with new studies and investigations. The Third Edition boasts six new chapters of coverage to expand the exploration of deception addressing advances in the field, and our current understanding of the phenomenon.

Detecting Malingering and Deception: Forensic Distortion Analysis (FDA-5) (Pacific Institute Series on Forensic Psychology)

Detecting Malingering and Deception: Forensic Distortion Analysis (FDA-5), Third Edition maintains the tradition of the prior two editions, following the Forensic Distortion Analysis (FDA) model. Fully updated since the last edition nearly 20 years ago, the book continues to serve as comprehensive volume on deception and distortion in forensic, clinical and several specialized contexts. As with the previous editions, the book presents a model of deception intended to be utilized and applied by the qualified evaluator. The proposed model covers targets of the faker, response styles show, and methods to detect the deception. The goal is to summarize the historical and latest information on distortion detection, to present guidelines for detecting deception that include variable accuracy rates based on different detection techniques, and to stimulate further research of effective methods of deception detection. Recommendations and guidelines for the practicing clinician are offered throughout the book, including real-world cases to inform and enlighten, particularly in unique cases or those in which the certain outcomes are unexpected. Key Features: Outlines the role of the forensic professional in applying and integrating methods assessment in deception and distortion Provides base-rates for deception-related behavior and events, especially useful in report writing or courtroom testimony as an expert witness Presents the latest advances in methodology and technology to assist in the search for ground truth in applied settings and situations Applies forensic distortion analysis to evaluate the deception-related findings and statements of other professionals involved in a particular case New coverage includes sections and chapters on deception analysis for collectivities, including media groups, contemporary politics, cross-national corporations, conflict, and terrorism Detecting Malingering and Deception incorporates the latest research, providing practical application to utilize information and evaluative methods as they pertain to deception-related settings and situations. Sample reports and extensive graphs, tables, charts, and histograms are provided, and every chapter has been updated with new studies and investigations. The Third Edition boasts six new chapters of coverage to expand the exploration of deception addressing advances in the field, and our current understanding of the phenomenon.

Detection and Assessment of Dental Caries: A Clinical Guide

This book explains how to optimize clinical conditions for detection of the earliest visible signs of dental caries and how best to assess caries activity as a basis for effective management. The available evidence from the literature on detection criteria and methods is distilled and placed in a clinical context to facilitate implementation in clinical practice. Guidance is offered on removal of the dental biofilm and the potential impact of various factors on the performance of different caries detection devices. The histological changes that occur during the caries process and their effect on the clinical appearance of caries lesions are explained. In addition, several caries classification systems based on visual detection criteria and designed to allow staging are presented. Consideration is also given to currently marketed detection aids, including methods involving light fluorescence, transillumination, and radiography. In each case, a summary of the detection performance, based on available supporting evidence, is tabulated together with advice on appropriate clinical application. The reader will find the text to be clearly written and informative, with many supporting clinical images.

Detection and Measurement of Visual Impairment in Pre-Verbal Children: Proceedings of a workshop held at the Institute of Ophthalmology, London on April 1–3, 1985, sponsored by the Commission of the European Communities as advised by the Committed on Medical Research (Documenta Ophthalmologica Proceedings Series #45)

Over the past few years there have been considerable advances in our understanding of the normal development of vision and in our ability to detect and meaSl1re visual impairment in early childhood. It was appropriate, therefore, that a workshop, sponsored by the European Communities, should be held on the 'Detection and Measurement of Visual Impairment in Pre-verbal Children.' This workshop, which was held at the Institute of Ophthalmology, London, between 1 and 3 April 1985, brought together visual physiologists and ophthalmologists who exchanged and discussed ideas of mutual interest. After an introductory session when the normal development of vision and the causes of visual impairment were reviewed, there were sessions devoted to the theoretical aspects of electrophysiological and psychophysical tests, the measurement of visual acuity in pre-verbal children, the measurement of other visual functions, and visual screening of pre-verbal children. This volume contains the papers presented at the workshop, and transcripts of the various discl1ssions that took place. It was a measure of the success of the workshop that participants from several different disciplines were able to have fruitful discussions and to suggest areas of common interest where collaborative ventures could usefully be pursued. It is hoped that this venture will be followed by others where a mul ti­ disciplinary approach will improve both our knowledge of visual handicap in childhood and our management of this important group of sensorily impaired children.

Detection and Quantification of Antibodies to Biopharmaceuticals: Practical and Applied Considerations

The definitive book on the neutralization of recombinant biopharmaceuticals Recombinant biopharmaceuticals are an important tool for treating a range of illnesses; however, their efficacy can be severely impaired by their immunogenicity. When introduced into the body, these pharmaceuticals can cause the immune system to produce anti-drug antibodies (ADAs) that neutralize their effects. The first and only book to cover neutralization in connection with biopharmaceuticals and the measurement and application of neutralizing antibodies in modern medicine at any real length, Detection and Quantification of Antibodies to Biopharmaceuticals: Practical and Applied Considerations offers a comprehensive and in-depth look at all the principal aspects of the detection and quantification of antibodies that are essential to understanding and responding to the challenges they present. Bringing together a large-scale review of neutralization and biopharmaceuticals and the ability to measure, detect, and apply antibodies to modern science and medicine with international regulatory perspectives, the expectations of regulatory authorities, and the strengths and weaknesses of various assays, the book describes several novel ideas for detecting ADAs. Designed to serve as a resource for biopharmaceutical drug development, the book provides biotechnology companies and pharmaceutical drug development specialists, as well as non-experts, with key insights into the design, optimization, and qualification of assays, the establishment of sampling strategies, the choice of appropriate assay end-points, and data analysis for the detection and quantification of neutralizing antibodies.

Detection and Quantification of Antibodies to Biopharmaceuticals: Practical and Applied Considerations

The definitive book on the neutralization of recombinant biopharmaceuticals Recombinant biopharmaceuticals are an important tool for treating a range of illnesses; however, their efficacy can be severely impaired by their immunogenicity. When introduced into the body, these pharmaceuticals can cause the immune system to produce anti-drug antibodies (ADAs) that neutralize their effects. The first and only book to cover neutralization in connection with biopharmaceuticals and the measurement and application of neutralizing antibodies in modern medicine at any real length, Detection and Quantification of Antibodies to Biopharmaceuticals: Practical and Applied Considerations offers a comprehensive and in-depth look at all the principal aspects of the detection and quantification of antibodies that are essential to understanding and responding to the challenges they present. Bringing together a large-scale review of neutralization and biopharmaceuticals and the ability to measure, detect, and apply antibodies to modern science and medicine with international regulatory perspectives, the expectations of regulatory authorities, and the strengths and weaknesses of various assays, the book describes several novel ideas for detecting ADAs. Designed to serve as a resource for biopharmaceutical drug development, the book provides biotechnology companies and pharmaceutical drug development specialists, as well as non-experts, with key insights into the design, optimization, and qualification of assays, the establishment of sampling strategies, the choice of appropriate assay end-points, and data analysis for the detection and quantification of neutralizing antibodies.

Detection of Bacteria, Viruses, Parasites and Fungi: Bioterrorism Prevention (NATO Science for Peace and Security Series A: Chemistry and Biology)

This publication represents the result of the fruitful workshop organised with the aim to attract the attention on the possibility of bio terrorism attack, with the s- port of NATO funds. In the last years the attention was strongly concentrated on the terrorism view similar to “military type attacks:” bomb on the trains, kamikazes, airplanes etc. As consequence many devices studied are directed to prevent these attacks such as the control of the passengers before the flight. For the people terrorism is therefore equivalent to bomb or similar and nobody think that there is also other possible and sophisticated means that can be used by the terrorist. In 1995 Sarin gas in the Tokio subway killed 12 people and affected 5,000 persons. In the USA anthrax was sent by mail to many federal offices. These events and other cases attract the attention on these possible terrorist attacks and the first recommendations for preventing theses events were\elaborated in the United State and in Europe. The possible agents and the modality that can be used for the diffusion are analysed and food and water are considered the principal and more favourable way. The story and the principal decision about this were reported in the first article of this collection which introduces the concept of bio-terrorism.

Detection of Change: Event-Related Potential and fMRI Findings

This volume presents the first systematic overview of how event-related brain potential (ERP), cognitive electroencephalography (EEG), and functional magnetic imaging (fMRI) measures reflect the mental events arising from changes in sensory stimulation. The contents are fresh, the literature distillations highly informative, and the range of topics extremely useful for cognitive neuroscientists, psychologists, and researchers.

Detection of Fetal Abnormalities Based on Three Dimensional Nuchal Translucency (SpringerBriefs in Applied Sciences and Technology)

Ultrasound (US) prenatal screening has been proposed as the most effective technique for Trisomy 21 early assessment. Assessment of Nuchal Translucency (NT) offers promising non-invasive method for fetal abnormalities detection up to 75%. Nevertheless, current clinician practice of NT examination by locating the sonogram calipers on 2D US image requires highly trained and competent operators by adhering to a standard tedious protocol; therefore it is prone to errors and hence it decreases the reliability in intra- and inter-observer repeatability. This Brief provides the basic knowledge regarding Trisomy 21 diseases and its existing detection methods. The restrictions and disadvantages of each method are discussed accordingly. Therefore, a non-invasive early detection method using 3D ultrasound reconstruction of Nuchal Translucency is introduced. This new method for 3D NT assessments has an edge over the previous 2D methods, and entails the composite function in visualizing the explicit internal marker structure. Further, image processing techniques covered from data acquisition, pre-processing, speckle noise reduction and 3D segmentation are also discussed. This should be especially useful for students and professional researchers in the Biomedical and image processing fields.

Detection of Ischemic Myocardium with Exercise

The detection of ischemic myocardium is one of the major problems in modern cardiology. Exercise has long been used to detect latent myocardial ischemia by enhancing oxygen de­ mand, but different cardiologists perform exercise tests in dif­ ferent ways. In addition, many new techniques for detection of ischemia have been developed in the past decade. For these reasons, a symposium on this topic was organized in Dusseldorf under the auspices of the European Society of Cardiology. The papers from this symposium contained herein provide an up-to-date review of the different forms of exercise tests, including their advantages and disadvantages. Indications for study, recording techniques and evaluation of exercise ECG, including computer techniques, are extensively discussed. The results of exercise ECG are compared with those of other me­ thods, especially coronary angiography. Finally, the prognostic value of exercise ECG is assessed. Additional chapters deal with complementary methods for detection of myocardial ischemia, presenting techniques and results of angiographic, isotopic and metabolic studies under exercise. The symposium demonstrates that exercise testing has a primary role in the detection of the disease, but there is still no unanimity on how to carry it out. The results of some new approaches are promising, even if their clinical relevance has not yet been fully established. We hope that this book will be of interest to all our colleagues taking care of cardiac patients. We wish especially to thank Mr. M. Giicker and Mrs. B.

Detection of Malingering during Head Injury Litigation

Increased public awareness of traumatic brain injuries has fueled a number of significant developments: on the one hand, more funding and more research related to these injuries and their resulting deficits; on the other, the possibility of higher stakes in personal injury suits—and more reasons for individuals to feign injury. Expanding both the conceptual and clinical knowledge base on the subject, the Second Edition of Detection of Malingering during Head Injury Litigation offers the latest detection tools and techniques for veteran and novice alike. As in its initial incarnation, this practical revision demonstrates how to combine clinical expertise, carefully-gathered data, and the use of actuarial models as well as common sense in making sound evaluations and reducing ambiguous results. And, the book navigates the reader through the many caveats that come with the job, beginning with the scenario that an individual may be malingering despite having an actual brain injury. Among the updated features: •Specific chapters on malingering on the Halstead-Reitan, Luria-Nebraska, and MMPI-2. •A framework for distinguishing genuine from factitious PTSD in head injury cases. •Detailed information regarding performance on the WMT, MSVT, and NV-MSVT by children with developmental disabilities. •Guidelines for explaining symptom validity testing to the trier of fact. •Entirely new chapters on mild TBI and on malingering of PTSD symptoms in the context of TBI litigation. Professional neuropsychologists and forensic psychologists will appreciate this new edition of Detection of Malingering during Head Injury Litigation as an invaluable source of refinements to their craft, and improvement as an expert witness.

Detection of Malingering during Head Injury Litigation

Expanding both the conceptual and clinical knowledge base on the subject, the Third Edition of Detection of Malingering during Head Injury Litigation offers the latest detection tools and techniques for veteran and novice alike. Increased public awareness of traumatic brain injuries has fueled a number of significant developments: on the one hand, more funding and more research related to these injuries and their resulting deficits; on the other, the possibility of higher stakes in personal injury suits—and more reasons for individuals to feign injury.As in its earlier editions, this practical revision demonstrates how to combine clinical expertise, carefully-gathered data, and the use of actuarial models as well as common sense in making sound evaluations and reducing ambiguous results. The book navigates the reader through the many caveats that come with the job, beginning with the scenario that an individual may be malingering despite having an actual brain injury. Among the updated features:Specific chapters on malingering on the Word Memory Test (WMT), Test of Malingered Memory (TOMM) MMPI-2, MMPI-RF and MMPI-3;Detailed information regarding performance on performance validity tests in the domain of executive functioning and memory, Guidelines for explaining performance and symptom validity testing to the trier of fact;Chapters on mild TBI in children in head injury litigation, cultural concerns and ethical issues in the context of head injury litigation.

Detection of Malingering during Head Injury Litigation (Critical Issues in Neuropsychology)

Neuropsychologists and forensic psychologists have long lacked a systematic, scientific means of assessing head injury cases, of distinguishing those plaintiffs whose pain and suffering is real and deserves just compensation from those who are simply faking it. Cecil R. Reynolds and his expert contributors provide the first definitive work on this subject, focusing on problems that beset clinicians who are called upon to evaluate head injuries in civil courts. They describe the major malingering detection techniques currently in use.

The Detection of New Adverse Drug Reactions: (pdf)

The Detection of New Adverse Drug Reactions: (pdf)

Detection of Non-Amplified Genomic DNA (Soft and Biological Matter)

This book offers an overview of state-of-the-art in non amplified DNA detection methods and provides chemists, biochemists, biotechnologists and material scientists with an introduction to these methods. In fact all these fields have dedicated resources to the problem of nucleic acid detection, each contributing with their own specific methods and concepts. This book will explain the basic principles of the different non amplified DNA detection methods available, highlighting their respective advantages and limitations. Non-amplified DNA detection can be achieved by adopting different techniques. Such techniques have allowed the commercialization of innovative platforms for DNA detection that are expected to break into the DNA diagnostics market. The enhanced sensitivity required for the detection of non amplified genomic DNA has prompted new strategies that can achieve ultrasensitivity by combining specific materials with specific detection tools. Advanced materials play multiple roles in ultrasensitive detection. Optical and electrochemical detection tools are among the most widely investigated to analyze non amplified nucleic acids. Biosensors based on piezoelectric crystal have been also used to detect unamplified genomic DNA. The main scientific topics related to DNA diagnostics are discussed by an outstanding set of authors with proven experience in this field.

Detectors in Particle Physics: A Modern Introduction

This textbook provides an accessible yet comprehensive introduction to detectors in particle physics. It emphasises the core physics principles, enabling a deeper understanding of the subject for further and more advanced studies. In addition to the discussion of the underlying detector physics, another aspiration of this book is to introduce the reader to practically important aspects of particle detectors, like electronics, alignment, calibration and simulation of particle detectors. Case studies of the various applications of detectors in particle physics are provided.The primary audience is graduate students in particle or nuclear physics, in addition to advanced undergraduate students in physics.Key Features: Provides an accessible yet thorough discussion of the basic physics principles needed to understand how particle detectors work. Presents applications of the basic physics concepts to examples of modern detectors. Discusses practically important aspects like electronics, alignment, calibration and simulation of particle detectors. Contains exercises for each chapter to further understanding. For more information and errata please see the authors companion webpage https://ppdetectors.web.ox.ac.uk/This webpage also allows instructors to request a copy of the solutions manual. This eBook was published Open Access with funding support from the Sponsoring Consortium for Open Access Publishing in Particle Physics (SCOAP3).

Detectors in Particle Physics: A Modern Introduction

This textbook provides an accessible yet comprehensive introduction to detectors in particle physics. It emphasises the core physics principles, enabling a deeper understanding of the subject for further and more advanced studies. In addition to the discussion of the underlying detector physics, another aspiration of this book is to introduce the reader to practically important aspects of particle detectors, like electronics, alignment, calibration and simulation of particle detectors. Case studies of the various applications of detectors in particle physics are provided.The primary audience is graduate students in particle or nuclear physics, in addition to advanced undergraduate students in physics.Key Features: Provides an accessible yet thorough discussion of the basic physics principles needed to understand how particle detectors work. Presents applications of the basic physics concepts to examples of modern detectors. Discusses practically important aspects like electronics, alignment, calibration and simulation of particle detectors. Contains exercises for each chapter to further understanding. For more information and errata please see the authors companion webpage https://ppdetectors.web.ox.ac.uk/This webpage also allows instructors to request a copy of the solutions manual. This eBook was published Open Access with funding support from the Sponsoring Consortium for Open Access Publishing in Particle Physics (SCOAP3).