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Diagnosis and Therapy of Coronary Artery Disease

by Peter F. Cohn

Because the increasing complexities of diagnos­ testing and training, for example) are of neces­ ing and treating coronary artery disease are at sity discussed in more than one chapter with times overwhelming for many physicians, the appropriate cross referencing. Special attention purpose of this book is to bring together in one has been directed at making the references as comprehensive yet reasonably concise text a current as possible. Since the aim of the book is to do more than just update the concepts, the scholarly but clinically oriented analysis of the reader is also informed of the pertinent contro­ major aspects of coronary artery disease. The book is mainly intended for internists versies in the field. The word controversy is used in its most liberal form, so as to include areas of and clinical cardiologists as well as for those in training for these respective disciplines, but it disagreement or of uncertainty as well as should also be of interest to primary care physi­ changes in traditional views. Each of the con­ cians responsible for the management of pa­ tributors has been asked to identify specifically tients with coronary artery disease. Each of the the most important of the controversies in his contributors-whether cardiologist, radiologist, particular area of interest and to address himself or surgeon-has been selected for his special to these issues in the course of the chapter.

Diagnosis and Therapy of Malignant Lymphoma (Recent Results in Cancer Research #46)

by K. Musshoff

K. MUSSHOFF The group of diseases known as malignant lymphomas are, for a number of reasons, of equal interest to theoretical and clinical medicine. New findings in the fields of virology and immunology could conceivably shed some light on the so far unknown etiology of malignant lymphomas. A viral etiology could explain many of the dis­ parate findings with such a puzzling disease as lymphogranulomatosis, which shows both all the signs of malignancy, such as the characteristic Reed-Sternberg and Hodgkin cells and chromosome abnormalities, and those of an inflammatory disease, i.e. typical changes in the blood count and bone marrow and in the distribution of serum proteins. So far we have not been able to identify the etiology of this disease. However, clinical observations and pathomorphological investigations involving a joint effort by different branches of medicine have brought us closer to an understanding of the clinical picture. Descriptive anatomy has given us a clear picture of the regional distribution of the lymphatic system, which has long been neglected in the past. The introductory paper by Dr. S. KUBIK (Zurich), who has made valuable contributions to our knowl­ edge of the anatomy of the lymphatic system, deals with this subject.

Diagnosis and Therapy of Porphyrias and Lead Intoxication: International Symposium Clinical Biochemistry

by Manfred Doss

On the occasion of the 450th anniversary of Philipp University, the porphyrin research group of. the Department of Clinical Biochemistry in the Faculty of Medicine organized an international symposium. This was held between June 28 and July 1, 1977, under the joint chairman­ ship of Professor Samuel Schwartz and the editor. The organizers and chairmen of the symposium wish to thank the Sozialminister of Hessen, Armin Clauss, the President of the German Society for Clinical Chemis­ try, Professor A. Delbrlick, and the Dean of the Faculty of Medicine of Philipp University, Professor F. Neurath, for their support and patronage. We are also grateful to Professor A. Treibs of the Institute of Organic Chemistry, Technical University of Munich. Professor Treibs, a former pupil, co-worker and now successor to the Nobel laureate Hans Fischer, kindly accepted the honorary presidency of this international symposium. The opening ceremony was inaugurated by the chairmen, with welcoming speeches by the President of Philipps University, Mr. Rudolf Zingel and patrons of the university. The editor outlined the 10 years of development of clinical biochemistry at Philipp University and traced in detail the continual development of its chief research effort in porphyria. It was pointed out that following the first international symposium on the regulation of porphyrin and heme biosynthesis in 1973 at Marburg (Doss, M. (ed. ): Regulation of Porphyrin and Heme Biosyn­ thesis.

Diagnosis and Therapy of Spinal Tumors (Medical Radiology)

by Paul R. Algra L. Baert Jaap Valk Jan J. Heimans

Many different opinions exist as to the appropriate diagnostic workup and therapy for spinal tumors. With the advent of new imaging techniques and therapeutic regimens, an up-to-date reference work has become an urgent requirement. This book is designed to meet this need, and is the first of its kind to offer an overview of the opinions of internationally renowned specialists in the field. By addressing in detail all of the relevant topics and areas of contention, it should prove of great value in establishing rational imaging and therapeutic protocols for spinal tumors.

Diagnosis and Treatment in Internal Medicine

by Patrick Davey David Sprigings

Diagnosis and Treatment in Internal Medicine equips trainee doctors with the essential skills and core knowledge to establish a diagnosis reliably and quickly, before outlining the management of the clinical condition diagnosed. Organised into three sections, the first provides a vital overview, whilst the second focuses on common presentations and diagnoses. Uniquely, this new book shows readers how to turn symptoms into a list of diagnoses ordered by probability - a differential diagnosis. Experienced consultants who teach trainees every day demonstrate how to derive an ordered differential diagnosis, how to narrow this down to a single diagnosis and if not, how to live with diagnostic uncertainty. The final section provides a comprehensive account of the management of system-based syndromes and diseases. Highly-structured chapters emphasize how common conditions present, how to approach a diagnosis, and how to estimate prognosis, treatment and its effectiveness. An onus is placed on the development of crucial diagnostic skills and the ability to devise evidence-based management plans quickly and accurately, making this an ideal text for core medical trainees.

Diagnosis and Treatment in Internal Medicine


Diagnosis and Treatment in Internal Medicine equips trainee doctors with the essential skills and core knowledge to establish a diagnosis reliably and quickly, before outlining the management of the clinical condition diagnosed. Organised into three sections, the first provides a vital overview, whilst the second focuses on common presentations and diagnoses. Uniquely, this new book shows readers how to turn symptoms into a list of diagnoses ordered by probability - a differential diagnosis. Experienced consultants who teach trainees every day demonstrate how to derive an ordered differential diagnosis, how to narrow this down to a single diagnosis and if not, how to live with diagnostic uncertainty. The final section provides a comprehensive account of the management of system-based syndromes and diseases. Highly-structured chapters emphasize how common conditions present, how to approach a diagnosis, and how to estimate prognosis, treatment and its effectiveness. An onus is placed on the development of crucial diagnostic skills and the ability to devise evidence-based management plans quickly and accurately, making this an ideal text for core medical trainees.

Diagnosis and Treatment of Anal Fistula

by Renjie Shi Lihua Zheng

This book offers an interdisciplinary reference for diagnosis and treatment of anal fistula. First chapters provide state of the art review of anatomy, etiology, sign and symptoms, medical findings and differential diagnosis of anal fistula. The following chapters cover surgical and non-surgical treatment of anal fistula. Other important chapter presents diagnosis and treatment of special anal fistula, including anal fistula of Crohn’s disease, anal fistula in infants, tuberculous anal fistula, and anal fistula associated with AIDS. It will appeal to proctologists and surgeons in gastroenterology.

Diagnosis and Treatment of Autism

by Christopher Gillberg

In 1987, The Swedish Medical Research Council's Group for Evaluation of Medical Technology approached me on the subject of organizing a conference on Autism - Diagnosis and Treatment. The original idea for this conference had come from a Stockholm politician, Leni Bjorklund, who had felt that, at least in Sweden, autism appeared to be an area in which conflicting views on etiology and treatment had led to children and parents not always receiving adequate help. Professors Agne Larsson, MD, Tore Schersten, MD and Bjorn Smedby, MD in particular showed a keen interest and it was decided to hold a State-of-the-Art-Conference on autism in Gothenburg. The State-of-the-Art-Conference on Autism -Diagnosis and Treatment was held in Gothenburg May 8 -10, 1989. A panel of international experts was selected because of outstanding research or clinical activity in the field and in order to represent a wide variety of professional and theoretical approaches ranging from epidemiology, neurobiology and cognitive psychology to psychiatry, neurology, education, behavioural treatment and psychoanalysis. A group of professional observers involved in the field of autism was chosen so as to cover Sweden in a representative fashion. This group consisted of administrators, child psychiatrists, psychologists, social workers, pediatricians, nurses and teachers.

The Diagnosis and Treatment of Breakthrough Pain (Oxford American Pain Library)

by Perry Fine

Breakthrough pain (BTP) is episodic pain that emerges through the treatment of otherwise well-managed chronic background pain. Often called pain flare or transient pain, BTP negatively affects the function and quality of life of the patient and often results in a number of other physical, psychological and social problems. Breakthrough pain is a common occurrence affecting approximately two-thirds of the estimated 50 to 100 million chronic pain sufferers in the US. It can have multiple causes with various pathophysiologies, and can present with numerous clinical features and complications. The clinical features vary from individual to individual, and may vary within an individual over time. The successful management of breakthrough pain depends on proper assessment, treatment, and reassessment. Inadequate assessment can lead to ineffective or inappropriate treatment. Similarly, inadequate reassessment may lead to continuance of ineffective or even harmful treatment. In recent years, the need to educate physicians about pain management has been garnering increased attention from prominent medical associations and the media. Despite ongoing efforts to improve pain treatment, however, the need persists for evidence-based educational materials for physicians in the area of pain diagnosis and management. Part of the Oxford American Pain Library, this highly practical guide covers current approaches and new developments in the assessment and management of Breakthrough Pain, including both cancer-related pain and non-cancer chronic pain. It addresses the roles of opioid and non-opioid pharmacotherapy and presents non-pharmacologic interventions, as well. This concise yet comprehensive reference on Breakthrough Pain is ideal for palliative care doctors, anesthesiologists, pain medicine specialists and oncologists, as well as for primary care physicians and internists on the frontlines of care.

Diagnosis and Treatment of Cancer using Thermal Therapies: Minimal and Non-invasive Techniques

by Citlalli J. Trujillo-Romero Dora-Luz Flores

New research is being conducted in the diagnosis and new treatments of cancer that has high efficacy and are minimally invasiveness. Artificial intelligence, bioimpedance, thermal images and nanomaterials have been used to provide early diagnosis. New treatments based on the generation of microwaves, radiofrequency, or ultrasound have been proposed in the last couple of decades. Although thermotherapies have been shown to be efficient, for them to be considered as a primary treatment, they must overcome some hurdles. One of the main challenges is to ensure applicators that point the electromagnetic or the mechanical waves at a tumor, don't affect the surrounding healthy tissues. In some cases, nanoparticles have also been designed to achieve better focus. The design of new applicators can be made by computational models based on methods such as the finite element. However, to efficiently predict the applicator’s performance, it is important that dielectric, thermal, and acoustic properties (tissue characterization) are included in the models. Not only healthy tissue, but also tumors must be characterized. Patient specific treatment planning, which consists of a 3D patient model based on medical images, can be developed to implement a safety treatment. Moreover, tissue properties as well as the applicator must be defined. Parameters such as temperature increase, and heat pattern must be evaluated to ensure patient safety and treatment success.

Diagnosis and Treatment of Cancer using Thermal Therapies: Minimal and Non-invasive Techniques


New research is being conducted in the diagnosis and new treatments of cancer that has high efficacy and are minimally invasiveness. Artificial intelligence, bioimpedance, thermal images and nanomaterials have been used to provide early diagnosis. New treatments based on the generation of microwaves, radiofrequency, or ultrasound have been proposed in the last couple of decades. Although thermotherapies have been shown to be efficient, for them to be considered as a primary treatment, they must overcome some hurdles. One of the main challenges is to ensure applicators that point the electromagnetic or the mechanical waves at a tumor, don't affect the surrounding healthy tissues. In some cases, nanoparticles have also been designed to achieve better focus. The design of new applicators can be made by computational models based on methods such as the finite element. However, to efficiently predict the applicator’s performance, it is important that dielectric, thermal, and acoustic properties (tissue characterization) are included in the models. Not only healthy tissue, but also tumors must be characterized. Patient specific treatment planning, which consists of a 3D patient model based on medical images, can be developed to implement a safety treatment. Moreover, tissue properties as well as the applicator must be defined. Parameters such as temperature increase, and heat pattern must be evaluated to ensure patient safety and treatment success.

Diagnosis and Treatment of Chronic Cough

by Sang Heon Cho Woo-Jung Song

This book is a practical resource for clinicians who manage patients with chronic cough, which represents a major challenge in the clinic due to multiple diagnostic and therapeutic considerations. Essential assessments for cough and treatable traits are described, covering the upper and lower airways and the gastrointestinal tract, and appropriate treatments are identified according to the different findings and diagnoses. Based on recent mechanistic and clinical advances, the authors also discuss novel diagnostic and therapeutic options, including pharmacological and non-pharmacological approaches to control cough. Particular considerations of importance when dealing with chronic cough in children and the elderly are addressed separately. The book will be an invaluable guide and reference for all practitioners who require up-to-date information on how best to assess, diagnose, and treat patients with chronic cough.

Diagnosis and Treatment of Chronic Fatigue Syndrome and Myalgic Encephalitis: It's Mitochondria, Not Hypochondria

by Sarah Myhill

Mitochondria are the powerhouses of our cells, essential for the production and management of energy at the cell level. Dr. Sarah Myhill has spent years studying the relationship between mitochondrial malfunction and one of the most common problems that leads people to the doctor’s office: fatigue. In Diagnosis and Treatment of Chronic Fatigue Syndrome and Myalgic Encephalitis, Dr. Myhill examines this essential role of our mitochondria in energy production and why it is key to understanding and overcoming Chronic Fatigue Syndrome (CFS) and the inflammation that often accompanies it: Myalgic Encephalitis (ME). She explains the importance of healthy mitochondria, how we can assess how well they are functioning, what we can do to keep them healthy, and how to restore them to health if problems arise. Since publication of the first edition in 2014, new research and new clinical findings have shed further light on a condition that is debilitating to those who suffer from it, but “all in the head” to many doctors. The second edition of this groundbreaking book includes new insights and chapters on why CFS/ME is the most poorly treated condition in Western medicine, the role of the gut, allergy and autoimmunity, Lyme disease and other coinfections, reprogramming the immune system, reprogramming the brain, and the roadmap to recovery.

Diagnosis and Treatment of Erectile Disturbances: A Guide for Clinicians

by Harry W. Schoenberg R. TaylorSegraves

This book is the result of an informal association between the editors which extends back to 1974. At the beginning, it was a tenuous alliance between physicians in quite different medical subspecialties-urology and psychiatry. As the alliance was forged, subspecialty rivalries and mistrust were replaced by a common clinical interest in the diagnosis and treatment of erectile problems. We quickly became aware of the high prevalence of such disorders, how poorly prepared we were to make accurate and re­ sponsible diagnosis and treatment plans, and how complicated an etiol­ ogical diagnosis could prove to be. A variety of biological and psychological influences bear on sexual function, and in many clinical contexts, diagnosis and treatment planning involves consideration of complex interactive var­ iables. The need for an expanded multidisciplinary team became obvious. The requisite knowledge base extended across too many subspecialty boundaries, and the necessary information was not available in a conve­ nient source. As we began accumulating the information base, we became aware that this information might be of value to other physicians. The authors enjoy the luxury of an academic setting in which special expertise can be readily assembled. Such resources are often unavailable to the physician in practice. Thus, it is our hope that this text can serve as a multi specialty team for the physician in solo practice. R. TAYLOR SEGRAVES New Orleans, Louisiana HARRY W.

Diagnosis and Treatment of Fetal Disorders: Proceedings of the International Symposium on Diagnosis and Treatment of Disorders Affecting the Intrauterine Patient, Dorado, Puerto Rico, October 29–31, 1967

by Karlis Adamsons

HOWARD C. TAYLOR, JR. Medicine, through its long history, has continually striven to enlarge its scope. Success in these endeavors has come in sudden bursts with long intervals of relative quiescence between. As a result of the spectacular discoveries in the basic sciences during the last decades, medicine is again in a period of revolutionary advance in many fields. One of these is the subject of this report, "The Intrauterine Patient." Until recently the fetus signalized his presence only by the mother's enlarging abdomen and by his own movements, perceived by the preg­ nant woman herself and evident to the examining midwife and physician. Later, the sounds of the fetal heart heard by auscultation and the varia­ tions in its rate became the single important means by which the welfare of the fetus might be roughly determined and threats to his survival per­ haps detected. Otherwise, the fetus remained isolated, his condition unknown and any therapy consequent on diagnosis, except for the induc­ tion or termination of labor, nonexistent.

Diagnosis and Treatment of Fungal Infections (Infectious Disease)

by Duane R. Hospenthal Michael G. Rinaldi

Diagnosis and Treatment of Fungal Infections, 2nd Edition is a thorough update to Diagnosis and Treatment of Human Mycoses. Globally recognized experts are brought together again to provide the latest research and clinical evidence on fungal infections and basic mycology. This concise text is divided into sections dedicated to the patient approach, laboratory and radiological diagnosis, antifungal agents, mycoses and instructive cases. Ideal for patient care or as a teaching guide, the busy infectious disease, hematology, oncology, pulmonology, or critical care specialist will find this resource to be a practical tool for diagnosing, treating, and managing patients with fungal infections.

Diagnosis and Treatment of Fungal Infections

by Duane R. Hospenthal Michael G. Rinaldi Thomas J. Walsh

Diagnosis and Treatment of Fungal Infections, 3rd Edition contains the latest research and clinical evidence on fungal infections in humans. Updated again by globally recognized experts, this concise text is divided into sections dedicated to the patient approach, laboratory and radiological diagnosis, systemic antifungal agents, mycoses, and instructive cases. It is a concise but comprehensive resource for use in conjunction with patient care duties and in teaching. It is the perfect guide for hospital-based primary care physicians, oncologists, critical care specialists, and infectious disease fellows with limited training or experience in the identification and management of fungal infections.

Diagnosis and Treatment of Furcation-Involved Teeth

by Luigi Nibali

Diagnosis and Treatment of Furcation-Involved Teeth offers dental professionals a comprehensive review of the aetiology and diagnosis of furcation defects, including treatment options. Provides a practical manual for the successful diagnosis and treatment of a therapeutic challenge for general dentists and periodontists Presents illustrative photographs of clinical cases and procedures Offers a helpful chapter on patient-reported outcomes Includes a companion website with video clips and case studies

Diagnosis and Treatment of Furcation-Involved Teeth

by Luigi Nibali

Diagnosis and Treatment of Furcation-Involved Teeth offers dental professionals a comprehensive review of the aetiology and diagnosis of furcation defects, including treatment options. Provides a practical manual for the successful diagnosis and treatment of a therapeutic challenge for general dentists and periodontists Presents illustrative photographs of clinical cases and procedures Offers a helpful chapter on patient-reported outcomes Includes a companion website with video clips and case studies

Diagnosis and Treatment of Gastroesophageal Reflux Disease

by Michael F. Vaezi

This volume presents the most recent developments in diagnosis and treatment of patients with gastroesophageal reflux disease (GERD) and those who continue to be refractory to conventional GERD therapies. The book delineates the role of newly developed endoscopic therapies in GERD and outlines the best candidates for surgical fundoplication. Topics as the risks associated with GERD, lifestyle modification in GERD and the role of H2RA and proton pump inhibitor therapy in treating reflux disease are also explored.Written by authorities in the field, Diagnosis and Treatment of Gastroesophageal Reflux Disease is a concise yet comprehensive resource that is useful for primary care providers, gastroenterologists, pulmonologists, surgeons and ENT specialists.

Diagnosis and Treatment of Genitourinary Malignancies (Cancer Treatment and Research #88)

by Kenneth J. Pienta

The field of genito-urinary oncology is rapidly evolving at virtually every level. Significant advances have been made in our understanding of the molecular and cellular events which contribute to the generation of GU malignancies. At the same time, similar advances have been made in the clinical arena which have improved the diagnosis and treatment of urologic cancers. This volume attempts to summarize those advances which most impact us as clinicians, and has been divided into three sections. Section One, `Diagnostic advances: the use of molecular medicine in the diagnosis and prognosis of GU malignancies', details how epidemiologic studies and new molecular techniques are impacting our ability to diagnose and treat GU tumors. Section Two, `Surgical and radiation advances', details the recent major advances in the treatment of organ-confined cancers. Section Three, `Medical advances', addresses major issues in the treatment of metastatic disease. This volume will serve as a compendium of the advances, both at the basic science and clinical levels, which are currently impacting practicing oncologists and urologists.

Diagnosis and Treatment of Hair Disorders: An Evidence-Based Atlas

by Antonella Tosti Bianca Maria Piraccini

This new atlas provides a differential guide to diagnosis of disorders of the hair, as well as an evidence-based critique of the options for therapy. Covering evaluation methods, it also discusses the whole range of problems with hair, from disease and disorders induced by treatment to problems concerning special groups of patients.Presenting the l

Diagnosis and Treatment of Human Mycoses (Infectious Disease)

by Duane R. Hospenthal Michael G. Rinaldi

Diagnosis and Treatment of Human Mycoses brings together globally-recognized mycoses experts to guide readers in the use of current knowledge in the field of medical mycology to manage those who suffer from fungal infections (mycoses). Often, diagnostic strategies and tests, including basic and directed culturing techniques, histopathology with standard and special stains, serological methods, and radiological studies all need to be considered and commonly combined to make the diagnosis of fungal infection. This volume first introduces and reviews these tools separately and then as they pertain to specific infections or groups of diseases. The volume consists of four parts. Parts I-III provide an overview of diagnostic and therapeutic tools, and part IV presents the human mycoses.Diagnosis and Treatment of Human Mycoses is meant to be a concise text that will provide the busy infectious disease, hematology–oncology, pulmonology, or critical care specialist a practical tool to diagnose and manage fungal infections. In addition, the depth of the material in the text will provide these and other medical specialists and trainees an excellent reference and learning resource.

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