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The Effects of Drug Regulation: A survey based on the European Studies of Drug Regulation

by Graham Dukes

Most national governments have created agencies with the responsibility for deciding which medicinal drugs should be imported or manufactured and made available through their health systems. Many of these agencies were set up some twenty years ago in the wake of the thalidomide disaster. Since that time they have developed in quite different ways in response to national, cultural and economic influences. Their direct cost is very small in comparison to overall health budgets but their indirect effects, both in terms of health and the economy, can be substantial. In 1980 the World Health Organization (WHO) Regional Office for Europe set up a series of studies of drug evaluation in the European region aimed at determining the effects of the work of regulatory agencies on the availability of drugs, on the pharmaceutical industry, and on the health of individuals in the countries concerned. This book sets that work in a historical context and describes the sources of the data used by the project team and the methods used by WHO and others in assessing the work of these agencies and its repercussions for the community. Finally, it presents an analysis of current knowledge and the plans and prospects for future research. The first draft of this book was presented to a meeting of experts in the field of drug regulation at Oslo in March 1984, and the present text embodies the views and conclusions of that meeting.

The Effects of Estrogen on Brain Function

by Natalie L. Rasgon

This timely volume reviews current data on the effects of estrogen on the central nervous system, highlighting clinical aspects of this topic. Experts from the fields of psychiatry, pharmacology, neurology, and geriatrics collaborate to clarify the known risks and benefits of hormone therapy and explore questions that remain to be elucidated.Among the topics discussed:" Preclinical data on estrogen's effects on cognitive performance" The short-lived effects of hormone replacement therapy on cognitive function" Structural and functional brain imaging data regardingestrogen's effects on the central nervous system " Preclinical efforts to develop effective NeuroSERMs for the brain " The effects of estrogen on moodCiting the ongoing confusion over the risks and benefits of estrogen therapy, the contributors emphasize the need for additional research on medication, doses, preparations, methods of administration, alternative therapies, and supplements. This volume educates researchers, clinicians, and students on the current knowledge—including the effects of estrogen on mood, cognition, and brain metabolism—and provides guidelines for clinical practice and future research.Contributors: Roberta Diaz Brinton, Ph.D., University of Southern California; Cheri L. Geist, B.A., David Geffen School of Medicine, University of California at Los Angeles; Robert B. Gibbs, Ph.D., University of Pittsburgh School of Pharmacy; Eva Hogervorst, Ph.D., University of Loughborough and University of Oxford; Pauline M. Maki, Ph.D., Neuropsychiatric Institute, University of Illinois–Chicago; Peter J. Schmidt, M.D., National Institute of Mental Health; Daniel H. S. Silverman, M.D., Ph.D., David Geffen School of Medicine, University of California at Los Angeles; Katherine E. Williams, M.D., Stanford University School of Medicine; Kristine Yaffe, M.D., University of California, San Francisco, and San Francisco VA Medical Center; Laurel N. Zappert, B.A., Stanford University School of Medicine; Liqin Zhao, Ph.D., University of Southern California

Effects of Exercise on Hypertension: From Cells to Physiological Systems (Molecular and Translational Medicine)

by Linda S. Pescatello

As the first primer on the effects of exercise on human hypertension, Effects of Exercise on Hypertension: From Cells to Physiological Systems provides the state-of-the-art effects of exercise on the many possible mechanisms underlying essential hypertension in humans. The book contains chapters by distinguished experts on the effects of exercise on physiological systems known to be involved in hypertension development and maintenance as well as less well known aspects of hypertension such as 24-hour ambulatory blood pressure profile and oxidative stress. An emerging area, the effects of resistance exercise training on blood pressure is also covered. A unique aspect of the book is that it covers the effects of exercise mimetics on vascular cell adaptations in order to begin to elucidate some of the cellular mechanisms that may underlie blood pressure reductions with exercise training. Lastly, the book will end with a chapter on the interactive effects of genes and exercise on blood pressure. Chapters are grouped by physiological system or mechanism. The text begins with two overview chapters; one on the general effects of aerobic exercise training and the second on the general effects of resistance exercise training on blood pressure. Each chapter begins with a bulleted list of key points. Effects of Exercise on Hypertension: From Cells to Physiological Systems will be of great value to professional individuals in cardiovascular medicine, the cardiovascular sciences, allied health care professionals, and medical and graduate students in the cardiovascular sciences and medicine.

The Effects of Genetic Hearing Impairment in the Family

by Dafydd Stephens Lesley Jones

There has been an explosion of studies in the field of genetic hearing impairment in the past decade, associated with major advances in our understanding of the mechanisms and conditions involved. However, a recent review has highlighted the very limited number of studies on the effects of such hearing impairment on the individuals and families of those concerned. In The Effects of Genetic Hearing Impairment in the Family, under the aegis of the European Union GENDEAF programme, the editors have taken the first steps to address this deficit in our knowledge and understanding of this topic. The book addresses the problem by secondary analyses of existing large scale population studies, by prospective investigation of individuals with a family history of hearing impairment and by specific studies on patients with otosclerosis and neurofibromatosis 2 and their families. In addition several chapters look at the specific impact of deaf culture, ethnicity and religion on reactions to deafness and the specific needs in genetic counselling. This book represents an important first step in this field and should be an invaluable resource for all professionals involved with people with hearing impairments.

Effects of Hypergravity and Microgravity on Biomedical Experiments, The (Synthesis Lectures on Biomedical Engineering)

by Thais Russomano Gustavo Dalmarco Felipe Prehn Falcao

Take one elephant and one man to the top of a tower and simultaneously drop. Which will hit the ground first? You are a pilot of a jet fighter performing a high-speed loop. Will you pass out during the maneuver? How can you simulate being an astronaut with your feet still firmly placed on planet Earth? In the aerospace environment, human, animal, and plant physiology differs significantly from that on Earth, and this book provides reasons for some of these changes. The challenges encountered by pilots in their missions can have implications on the health and safety of not only themselves but others. Knowing the effects of hypergravity on the human body during high-speed flight led to the development of human centrifuges. We also need to better understand the physiological responses of living organisms in space. It is therefore necessary to simulate weightlessness through the use of specially adapted equipment, such as clinostats, tilt tables, and body suspension devices. Each of these ideas, and more, is addressed in this review of the physical concepts related to space flights, microgravity, and hypergravity simulations. Basic theories, such as Newton’s law and Einstein’s principle are explained, followed by a look at the biomedical effects of experiments performed in space life sciences institutes, universities, and space agencies. Table of Contents: General Concepts in Physics - Definition of Physical Terms / The Effects of Hypergravity on Biomedical Experiments / The Effects of Microgravity on Biomedical Experiments / References

The Effects of Immune Cells and Inflammation On Smooth Muscle and Enteric Nerves

by Jr. Snape Stephen M. Collins

This book provides the first comprehensive review of research that addresses the immunomodulation of gastrointestinal motility. Results from this new field of research are important for understanding motility disturbances and symptom-generation in a variety of clinical gastroenterological problems, including ulcerative colitis, Crohn's disease, enteric infections, and food allergies. The book provides overviews on current perspectives regarding the nature of inflammatory processes, inflammatory mediators, and other immune factors. It also describes a variety of experimental approaches that have been used to study the interactions between immune cells and smooth muscle or enteric nerves. The approaches include in vivo, as well as in vitro studies. Researchers involved in the general field of immunophysiology, as well as the more specific fields of gastrointestinal motility and inflammatory bowel diseases will find this book to be invaluable in their research.

The Effects of Immune Cells and Inflammation On Smooth Muscle and Enteric Nerves

by Jr. Snape Stephen M. Collins

This book provides the first comprehensive review of research that addresses the immunomodulation of gastrointestinal motility. Results from this new field of research are important for understanding motility disturbances and symptom-generation in a variety of clinical gastroenterological problems, including ulcerative colitis, Crohn's disease, enteric infections, and food allergies. The book provides overviews on current perspectives regarding the nature of inflammatory processes, inflammatory mediators, and other immune factors. It also describes a variety of experimental approaches that have been used to study the interactions between immune cells and smooth muscle or enteric nerves. The approaches include in vivo, as well as in vitro studies. Researchers involved in the general field of immunophysiology, as well as the more specific fields of gastrointestinal motility and inflammatory bowel diseases will find this book to be invaluable in their research.

The Effects of Intimate Partner Violence on Children

by Robert A. Geffner Robyn Spurling Igelman Jennifer Zellner

Learn how to help children cope with domestic violence! The Effects of Intimate Partner Violence on Children examines the short- and long-term developmental issues facing children exposed to violence in their own homes. The book addresses the growing concern for children at risk of suffering psychological, behavioral, social, and educational problems, and for the effects childhood maltreatment may have on their adult lives. An interdisciplinary panel of researchers, academicians, attorneys, clinicians, and practitioners discuss treatment programs, theoretical perspectives, research and methodological issues, assessment and intervention, and forensic issues, including child custody. The Effects of Intimate Partner Violence on Children addresses the emotional and behavioral disturbances children can suffer after being exposed to violence between their parents. It examines methodological and theoretical challenges, pilot programs for treatment, intervention models, therapeutic curricula, and family law. Practitioners and academics review dozens of studies, representative samples, probability samples, and research findings relating to children's internalizing and externalizing behaviors, adjustment difficulties, coping strategies. The book also examines: the association between emotional regulation and emotionality and marital and parent-child conflict in terms of children's adjustment and physical health how the experience of mothers in low-income families suffering severe physical abuse relates to children's behavior problems. how father-to-mother aggression reduces children's affinity with their parents problems of service delivery for battered mothers Canadian legislation involving wife abuse and child custody the well-being of families accessing treatment group interventions implemented in family agency and school settings how to develop interagency protocols and much more! The Effects of Intimate Partner Violence on Children is an essential resource for professionals, advocates, and practitioners who work with abused children and maltreating families.

The Effects of Intimate Partner Violence on Children

by Robert Geffner Jennifer Zellner Robyn Spurling Igelman

Learn how to help children cope with domestic violence! The Effects of Intimate Partner Violence on Children examines the short- and long-term developmental issues facing children exposed to violence in their own homes. The book addresses the growing concern for children at risk of suffering psychological, behavioral, social, and educational problems, and for the effects childhood maltreatment may have on their adult lives. An interdisciplinary panel of researchers, academicians, attorneys, clinicians, and practitioners discuss treatment programs, theoretical perspectives, research and methodological issues, assessment and intervention, and forensic issues, including child custody. The Effects of Intimate Partner Violence on Children addresses the emotional and behavioral disturbances children can suffer after being exposed to violence between their parents. It examines methodological and theoretical challenges, pilot programs for treatment, intervention models, therapeutic curricula, and family law. Practitioners and academics review dozens of studies, representative samples, probability samples, and research findings relating to children's internalizing and externalizing behaviors, adjustment difficulties, coping strategies. The book also examines: the association between emotional regulation and emotionality and marital and parent-child conflict in terms of children's adjustment and physical health how the experience of mothers in low-income families suffering severe physical abuse relates to children's behavior problems. how father-to-mother aggression reduces children's affinity with their parents problems of service delivery for battered mothers Canadian legislation involving wife abuse and child custody the well-being of families accessing treatment group interventions implemented in family agency and school settings how to develop interagency protocols and much more! The Effects of Intimate Partner Violence on Children is an essential resource for professionals, advocates, and practitioners who work with abused children and maltreating families.

Effects of Joint Incongruity on Articular Pressure Distribution and Subchondral Bone Remodeling (Advances in Anatomy, Embryology and Cell Biology #152)

by F. Eckstein B. Merz C.R. Jacobs

The objective of the present work is to review the existing literature on joint incongruity, cellular mechano-transduction, and computer simulations of mechano-adaptive bone remodelling, and to quantitatively assess the effect of incongruity on load transmission and subchondral mineralisation. Idealised computer models of incongruous joints and a specific anatomically based model of the humero-ulnar joint articulation were analysed with the finite element method, and the results directly compared with experimental and morphological data.

Effects of Mineral Dusts on Cells (Nato ASI Subseries H: #30)

by Brooke T. Mossman Raymond O. Begin

The Fourth International Workshop on "In Vitro Effects of Mineral Dusts on Cells" was held on September 20 - 23, 1988 in Auberge Estrimont, Orford, Quebec, Canada. The emphasis of the N. A. T. O. Advanced Research Workshop was the use of cell and organ culture and lavage cell populations obtained from man and laboratory animals to elucidate cellular and molecular events occur­ ring after their interaction with fibrous and nonfibrous particulates, including metal compounds. In seven sessions, an international representation of scientists from 17 countries (Austria, Belgium, Canada, France, Federal Republic of Germany, India, Japan, Netherlands, Norway, Poland, Portugal, Union of South Africa, Sweden, Switzerland, United Kingdom, United States of America, and Yugoslavia) presented recent research findings in the following areas: Epithelial cell injury and proliferation by minerals. Physico-chemical properties of minerals in relation to their biologic effects. Mechanisms of dust-induced pneumoconioses. Clinical and experimental studies. Mechanisms of cytotoxicity, mutagenicity and carcinogenicity. Oxidants, cytotoxicity and disease. Mechanisms of mineral-induced inflammation. Mechanisms of carcinogenesis. A session on "Questions, risk and public policy" provided a lively discussion on the relevance of in vitro experiments to carcinogenicity studies in man and their implications in the formation of regulatory policies. VI The organizing committee for this workshop was: Co-Chairs: B. T. Mossman (USA) and R. Begin (Canada) E. G. Beck (FRG) A. Lange (Poland) A. Brody (USA) P. Nettesheim (USA) R. C. Brown (UK) Q. Rahman (India) J. Bignon (France) K. Robock (FRG) Fisher G.

The Effects of Noise on Aquatic Life (Advances in Experimental Medicine and Biology #730)

by Arthur N. Popper and Anthony Hawkins

The Second International Conference on the Effects of Noise on Aquatic Life will take place in Ireland August 15-20, 2010. The main emphasis of the conference will be on defining the current state of knowledge. However, we will also assess progress in the three years since the First conference. The Second conference will place strong emphasis on recent research results, the sharing of ideas, discussion of experimental approaches, and analysis of regulatory issues.

The Effects of Noise on Aquatic Life II: 3rd International Conference (Advances in Experimental Medicine and Biology #875)

by Arthur N. Popper Anthony Hawkins

The meeting of Aquatic Noise 2013 will introduce participants to the most recent research data, regulatory issues and thinking about effects of man-made noise and will foster critical cross-disciplinary discussion between the participants. Emphasis will be on the cross-fertilization of ideas and findings across species and noise sources. As with its predecessor, The Effects of Noise on Aquatic Life: 3rd International Conference will encourage discussion of the impact of underwater sound, its regulation and mitigation of its effects. With over 100 contributions from leading researchers, a wide range of sources of underwater sound will be considered.

Effects of Opera Music from Brain to Body: A Matter of Wellbeing (Neurocultural Health and Wellbeing)

by Lorenzo Lorusso Michele Augusto Riva Vittorio Alessandro Sironi

This book explores the connection between melodrama and medicine from multiple perspectives. Neuroscientists study the relationship between opera and brain functioning in the light of new findings in the fields of neurophysiology, neuroimaging, cognitive science and neuro-musicology; clinicians investigate the therapeutic potential of music, especially in the field of treatment and rehabilitation of individuals with neurodegenerative diseases; medical historians analyse the representation of diseases and those who cure diseases within operas; occupational doctors report descriptions of diseases that affect workers in the opera world and particularly focus on psychiatric and psychological alterations. Opera, with its instrumental and vocal accompaniment, is considered the most complete form of theatrical performance. However, little is known about the mechanisms of brain activity under the influence of melodrama on singers, musicians, and listeners. The use of neuroimaging techniques has enabled a better understanding of the neuronal mechanisms and circuits involved during an opera performance. Over the past 20 years, melodrama has increasingly been used as a therapeutic approach in various neurological and neuropsychiatric pathologies, such as depression, cognitive impairment, and even coma. The book also discusses the ways in which melodrama affects professionals involved in music and interventions to reduce or alleviate occupational diseases, leading to improved health and higher life satisfaction. The ultimate goal is to improve therapeutic interventions in neurological diseases and professional disorders, relying on solid neuroscientific data. This book will be of great interest to neurologists, neurobiologists, psychiatrists, occupational doctors and therapists in music.

The Effects of Psychological Therapy: International Series in Experimental Psychology

by S. J. Rachman G. T. Wilson

The Effects of Psychological Therapy, Second Enlarged Edition focuses on trends, methodologies, and technologies used in determining the effects of psychological therapy on neurotic disorders, behavior therapy, and psychotherapy. The manuscript first discusses conventional outcome research, need for evaluations, and Eysenck's argument. The book also focuses on the spontaneous remission of neurotic disorders and effects of psychoanalytic treatment, including spontaneous remission rates in childhood, the American Psychoanalytic Association survey, Malan's contribution, and the Menninger clinic report. The text ponders on the effects of psychotherapy, Rogerian psychotherapy, and psychotherapy with psychotic patients. The manuscript also takes a look at behavior therapy, as well as external and internal validity of studies on systematic desensitazion, controlled-treatment outcome studies, and outcome of behavior therapy. Meichenbaum's self-instructional training, cognitive restructuring methods, and Beck's cognitive therapy are discussed. The manuscript is a dependable reference for readers interested in the effects of psychological therapy.

Effects of smoking- Pie Chart 1

by Sheffield Vi Service

This is a pie chart showing the effects of smoking on men aged 35 to 64.

The Effects of Social Health Insurance Reform on People’s Out-of-Pocket Health Expenditure in China: The Mediating Role of the Institutional Arrangement

by Kai Liu

This study examines and explains the relationship between social health insurance (SHI) participation and out-of-pocket expenditures (OOP) as well as the mediating role the institutional arrangement of SHI plays in this relationship in China. Embracing a new institutionalist approach, it develops two analytical perspectives: determination, which identifies the mechanisms of social health insurance, and strategic interaction, which explores the interaction among social health insurance agencies, healthcare providers, patients, and institutions. It reveals the poor performance of social health insurance in decreasing out-of-pocket health expenditures caused by a trade-off between the reimbursement, behavior management, and purchasing mechanisms of social health insurance programs. Further, it finds that the inequitable allocation of healthcare resources and patients’ concerns regarding the benefits offset the strategies used by social health insurance agencies to manage care-seeking behavior. It also discovers that the complex interactions between insurance agencies, doctors, patients and a larger disenabling institutional surrounding restricts the purchasing efficiency of social health insurance. This book is characterized by its unique synthesis of the role of the institutional arrangement of social health insurance in China, the interaction between the stakeholders in health sectors, and of the relationship between healthcare institutions, actors, and policy outcomes. Providing a comprehensive overview, it enables scholars and graduate students to understand the ongoing process of social health insurance reform as well as the dynamics of health cost inflation in China. It also benefits policymakers by recommending a single-payer model based on an evidence-based investigation.

The Effects of Taurine on Excitable Tissues: Proceedings of the 21st Annual A. N. Richards Symposium of the Physiological Society of Philadelphia, Valley Forge, Pennsylvania, April 23–24, 1979 (Monographs of the Physiological Society of Philadelphia #7)

by James J. Kocsis S. I. Baskin Stephen W. Schaffer

It has become an annual custom for the Physiological Society of Philadel­ phia to sponsor a spring symposium in honor of A. N. Richards (\876-1966), a research pharmacologist who developed the classical micropuncture tech­ nique for studying kidney function. The A. N. Richards Symposium for 1979 was held on April 23-24 in Valley Forge, Pennsylvania. The theme of this symposium was "The Actions of Taurine on Excitable Tissues." Although taurine was discovered as a constituent of bile salts in 1857 by a chemist and an anatomist (Gmelin and Tiedemann), interest today centers chiefly on the extrahepatic actions of taurine, especially in brain, heart, and other excitable tissues. Research on taurine is clearly in a period of exponential growth. We can be sure that the research reports presented and described herein as the "Proceedings of the Symposium" will provide impetus for further growth. Thus the report describing macromolecular receptors for taurine in myocardial sarcolemma may provide a model for exploring the molecular mechanisms that underlie the action(s) of taurine. Stabilization of mem­ branes and modulation of ion fluxes are two fundamental actions of taurine dealt with in many of these reports. It is just these actions of taurine that have been reported by several investigators as being involved in human myotonia, diabetes, and heart failure.

Effects of Temperature on Ectothermic Organisms: Ecological Implications and Mechanisms of Compensation

by Wolfgang Wieser

The study of thermoregulation in endotherms has contributed much to the emergence of the concept of control theory in biology. By the same token, the study of tempera­ ture adjustment in ectotherms is likely to have a far-reaching influence on ideas on the regulation of metabolism in general. The reason for this is that ectotherms, in adapting to the vagaries of a thermally unstable environment, deploy a range of subtle molecular and organismic strategies. Thus the experimenter, using temperature changes as a tool, is well equipped to analyze some of these strategies. This approach has enabled some important mechanisms of temperature-induced adaptation to be elucidated; the most striking of these are the effects on metabolism of changes in the conformation of enzymes and the transfer properties of membranes. Furthermore, there is a vague but persistent feeling among those working in this field that changes in the nervous system will ultimately prove to be the agency by which many of the molecular mechanisms of temperature adaptation are controlled. Should this indeed be the case, a new phase would soon begin in our understanding of the interactions between the systemic and the cellular levels of organization. However, it is not only questions about the causes of temperature adaptation that can provide answers of potential importance to the general biologist; of equal significance are questions as to the meaning of temperature adaptation in a particular organism.

The Effects of Whole-Body Vibration

by Heinrich Dupuis Georg Zerlett

The observations made by Paracelsus concerning the dose-effect relationship of poison are generally just as applicable to health­ threatening vibration. With regard to kind, intensity, and duration of the vibration, the "dose" is decisive as to whether the conse­ quences are detrimental, unmeaningful, or tolerable with respect to health. This law of nature determines the tasks and goals of those whose aim is to safeguard health. Researchers worldwide have been occupying themselves with this many-faceted question for some time: how mechanical vibration affects the human organism and at what point damage occurs. If prevention in occupational medicine is to succeed, it is most important that the gaps in our present knowledge be closed, for if technical preventive measures are to be effective and preventive means in occupational medicine successful, they must be based on reliable and complete findings. Whenever many independent researchers have worked in a given field for a long period, a comprehensive intermediate as­ sessment is appropriate to evaluate the level achieved and the direction the research is going. In the area of hand-arm vibration, this evaluation has already been carried out, and the response aroused by this particular research report had led to a demand for a comparable evaluation of the research results on whole-body vibration. This report presents clearly and exhaustively the current status of international knowledge, as well as the questions that remain to be answered.

Effekte der pulmonalen Ballonangioplastie auf die Herzfunktion bei inoperabler chronisch thromboembolischer pulmonaler Hypertonie

by Alexander Hasse

Die chronisch thromboembolische pulmonale Hypertonie (CTEPH) ist eine relativ seltene, aber unterdiagnostizierte Erkrankung, die durch wiederholte Einschwemmungen von thrombotischem Material in die pulmonalarteriellen Gefäße charakterisiert ist. Unbehandelt hat die Erkrankung durch progredientes Rechtsherzversagen eine schlechte Prognose. Die CTEPH ist jedoch die einzige potenziell kurativ behandelbare Erkrankung aus dem Formenkreis der pulmonalen Hypertonie. Mittels pulmonaler Endarteriektomie können operable Patienten geheilt werden. Für das inoperable Drittel der Patienten bietet sich als radiologisch-interventionelles Verfahren die pulmonale Ballonangioplastie (BPA) an. Um den Therapieerfolg dieser Intervention zu messen und etwaige prognostische Aussagen treffen zu können, ist neben der klinischen Evaluation weiterhin der Rechtsherzkatheter als Goldstandard unumgänglich. Als invasives Verfahren birgt es jedoch die Gefahr ernsthafter Komplikationen. Als nicht invasives und somit sichereres und schneller durchführbares Verfahren eignet sich die kardiale Magnetresonanztomographie. Diese Studie überprüft mittels Volumetrie, Strainanalyse und kardialem Mapping nun zunächst, ob die BPA einen positiven Effekt auf die (Rechts-) Herzfunktion und pulmonale Hämodynamik hat. Ferner werden Korrelationen zwischen pulmonaler Hämodynamik und Strainparametern sowie T1- und T2-Zeiten überprüft und ermittelt, inwiefern sich die rechtsventrikuläre Strainanalyse zur Kontrolle der Therapieeffekte eignet.

Effektivität der Ergotherapie im psychiatrischen Krankenhaus: Mit einer Synopse zu Geschichte, Stand und aktueller Entwicklung der psychiatrischen Ergotherapie (Monographien aus dem Gesamtgebiete der Psychiatrie #112)

by T. Reuster

Psychiatrische Ergotherapie wird in deutschsprachigen Kliniken extensiv eingesetzt. Ob sie einen effektiven Beitrag zur Therapie leistet, ist bisher nicht angemessen untersucht worden. Diese Arbeit leistet mit einem anspruchsvollen randomisierten Kontrollgruppen-Design zur Frage der therapeutischen Effektivität einen verallgemeinerbaren Beitrag. Dabei fokussiert sie auf die Kernstörungen Schizophrenie, Depression und Manie und deren Behandlung.

The Efferent System of Cranial Nerve Nuclei: A Comparative Neuromorphological Study (Advances in Anatomy, Embryology and Cell Biology #128)

by George Szekely Clara Matesz

A new approach using comparative neuromorphology is taken in this study dealing with the organization of the efferent nuclei of cranial nerves. The authors use the cobalt labelling technique to identify neuron types and follow their presence, or absence, in different animal species. They suggest a new classification which is free from a number of controversies inherent in the classical classification. The results suggest that evolutionary changes in the center and in the innervated periphary parallel each other with increasingly complex function.

Effetti, potenzialità e limiti della globalizzazione: Una visione multidisciplinare

by Gianluca Brunori Luca Ceccherini-Nelli Pierluigi Consorti Alessandro Franco Rossano Massai Paola Nieri Sandro Paci Marta Pappalardo Daniela Reali

Gli autori propongono una visione multidisciplinare che integra settori apparentemente lontani fra loro ma uniti dal tema della globalizzazione. Il volume raccoglie contributi di Economia, Giurisprudenza, Agraria, Ingegneria, Medicina, Farmacia, Biologia e Scienze della Terra. I diversi capitoli forniscono uno sguardo d'insieme sul tema della globalizzazione in maniera accessibile a tutti coloro che desiderano conoscere meglio la realtà dei nostri giorni senza rassegnarsi ad accettarne gli aspetti negativi.

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