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Modern Green Chemistry and Heterocyclic Compounds: Molecular Design, Synthesis, and Biological Evaluation (Innovations in Physical Chemistry)

This book covers the general properties of heterocyclic compounds and methods for their preparation to use in applications of green chemistry. Heterocyclic compounds are an important class of molecules in organic chemistry due to their presence in natural products and their use in pharmaceuticals and new materials. They also play a vital role in the metabolism of living cells. Heterocyclic compounds have a wide range of applications in agrochemicals, pharmaceuticals, veterinary products, etc. This research-oriented volume is ideal for readers who want to fully realize the almost limitless potential of heterocyclic compounds and to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features several case studies and step-by-step descriptions of synthetic methods and practical techniques. It also serves as a guide for chemists, offering them new insights and new paths to explore for effective drug discovery.

Modern Guide to GP Consulting

Dr. Alex Watson and actor Dave Gillespie have combined their different areas of expertise to produce a new approach to GP consulting. Modern Guide to GP Consulting is a simple and straightforward guide that any doctor can use to improve the way they communicate with their patients. For many years, General Practitioners have placed great emphasis an

Modern Head and Neck Imaging (Medical Radiology)

A comprehensive overview of the state of the art in imaging of the head and neck. The book discusses the role of the standard modalities such as MRI and CT in diagnosing and staging head and neck cancers and in evaluating the effectiveness of various treatment regimens. In addition, it provides extensive insight into the role of such emerging technologies as positron emission tomography, magnetic resonance spectroscopy, and 3D volume rendering. All the authors have extensive experience of these new modalities and techniques.

Modern Hematology: Biology and Clinical Management (Contemporary Hematology #864)

Now in its second edition, Modern Hematology: Biology and Clinical Management reflects the major advances in the understanding, diagnosis, and treatment of blood disorders. It describes the latest clinical and scientific developments as well as details targeted and molecular therapies. The book brings together facts, concepts, and protocols important for the practice of hematology. In 23 chapters, all major blood diseases are covered, as well as rare diseases that are of scientific interest. As in the previous edition, each chapter is illustrated by tables, figures, and a selection of color plates.

Modern Hematology: Biology and Clinical Management (Contemporary Hematology #864)

Modern Hip Preservation: New Insights In Pathophysiology And Surgical Treatment

This book comprehensively discusses both the history and the current concepts of modern hip preservation surgery. Offering an overview of the game-changing studies on the hip and pelvis vascular anatomy it thoroughly describes the evolution of a new and comprehensive pathophysiology of the hip joint degeneration. Moreover, in the first part, particular emphasis is devoted to the history and current knowledge of femoroacetabular impingement and hip dysplasia.The second part examines the main surgical procedures that have evolved and matured since the 1980s, culminating in a new class of open surgical approaches, such as hip surgical dislocation, periacetabular osteotomies, proximal femoral osteotomies and corrections, and widening the door for hip-arthroscopy. Based on over 40 years of practical and pioneering experience by the editor and 15 years of collaboration with the GICCA Study Group, this book offers a valuable resource to residents, researchers and practicing orthopedic surgeon wishing to gain insights into hip preservation surgery.

Modern Hip Resurfacing

Hip replacement surgery is a radical and traumatic procedure that has enormous disadvantages to the patient in terms of postoperative mobility and morbidity. Hip resurfacing is a more conservative approach resulting in less of the patient’s hip and femur being lost, which has great advantages to a younger patient group. The author of Hip Resurfacing is the world’s leading authority on this surgery, making this the definitive resource in hip resurfacing

Modern Hospice Design: The Architecture of Palliative and Social Care

The new edition of this acclaimed book comprehensively updates its timely advocacy of the need for good quality palliative care, today more necessary than ever. Rooted in the social history of the care of the elderly and terminally ill, Modern Hospice Design: The Architecture of Palliative and Social Care takes cognisance of the new conditions of social care in the 21st century, principally in the UK, Europe and North America. It does so with regard to the development of new building types, but also in response to new philosophies of palliative care and the status of the elderly and the dying. Benefitting from a clearer methodological approach and conceptual framework, the expanded book allows a broad section of readers to navigate the text more easily. At its core is a public discussion of a philosophy of design for providing care for the elderly and the vulnerable, taking the importance of architectural aesthetics, the use of quality materials, the porousness of design to the wider world, and the integration of indoor and outdoor spaces as part of the overall care environment. In doing so it advocates care settings that, in the words of Maggie Jencks whose life and ideas inspired the Maggie’s Centres, ‘rise to the occasion’. Including new chapters and new in-depth case studies, complete will full colour illustrations, this book is for architects and interior designers and their students, healthcare professionals, social care providers, estate and facility managers, hospital administrators and Healthcare Trust Boards.

Modern Hospice Design: The Architecture of Palliative and Social Care

The new edition of this acclaimed book comprehensively updates its timely advocacy of the need for good quality palliative care, today more necessary than ever. Rooted in the social history of the care of the elderly and terminally ill, Modern Hospice Design: The Architecture of Palliative and Social Care takes cognisance of the new conditions of social care in the 21st century, principally in the UK, Europe and North America. It does so with regard to the development of new building types, but also in response to new philosophies of palliative care and the status of the elderly and the dying. Benefitting from a clearer methodological approach and conceptual framework, the expanded book allows a broad section of readers to navigate the text more easily. At its core is a public discussion of a philosophy of design for providing care for the elderly and the vulnerable, taking the importance of architectural aesthetics, the use of quality materials, the porousness of design to the wider world, and the integration of indoor and outdoor spaces as part of the overall care environment. In doing so it advocates care settings that, in the words of Maggie Jencks whose life and ideas inspired the Maggie’s Centres, ‘rise to the occasion’. Including new chapters and new in-depth case studies, complete will full colour illustrations, this book is for architects and interior designers and their students, healthcare professionals, social care providers, estate and facility managers, hospital administrators and Healthcare Trust Boards.

The Modern Hospital: Patients Centered, Disease Based, Research Oriented, Technology Driven

The rapidly growing developments in medicine and science in the last few decades has evoked a greater need for modern institutions, with modern medicine, advanced technologies, and cutting edge research. Today, the modern hospital is a highly competitive, multibillion dollar industry that plays a large role in our healthcare systems. Far different from older institutions, modern hospitals juggle the dynamics of running a business that proves financially fruitful and sustainable, with maintaining and staying ahead of medical developments and offering the best possible patient care. This comprehensive book explores all aspects of the inner workings of a modern hospital, from research and technology driven treatment and patient centered care, to the organizational, functional, architectural, and ergonomic aspects of the business. The text is organized into three parts. The first part covers a number of important aspects of the modern hospital including hospital transformation over the centuries, the new medical world order, overall concept, academic mission and economics of new healthcare. Additionally, experts in the field address issues such as modern design functionally and creating an environment that is ergonomically friendly, technologically advanced, and easy to navigate for both worker and patient. Other topics covered include, the role of genomics and nano-technologies, controversies that come with introducing new technologies, the world-wide pharmaceutical industry, electronic medical health records, informatics, and quality of patient care. Part II addresses nine specific elements of modernization of the hospital that deal with high acuity, life and death situations, and complex medical and surgical diseases. These chapters cover the organization of new emergency departments, trauma room, hybrid operating rooms, intensive care units, radiology, pharmaceutical and nutritional support, and most essential, patient and public relation services. These nine elements reflect the most important and most visible indicators of modernization and transformation of the hospital. Part III examines and highlights the team approach as a crucial component of the transformation, as well as specific perspectives on the modern hospital from nurses, physicians, surgeons and administrators. Finally, a chapter dedicated to patient perspective is also presented. The Modern Hospital provides an all-inclusive review of the hospital industry. It will serve as a valuable resource for administrators, clinicians, surgeons, nurses, and researchers. All chapters will be written by practicing experts in their fields and include the most up-to-date scientific and clinical information.

Modern Imaging of the Alimentary Tube (Medical Radiology)

The many new developments in gastrointestinal imaging have created a need for a book devoted to imaging of the alimentary tube. This superbly illustrated and well referenced volume is specifically designed to meet this need. The new cross-sectional imaging techniques are clearly described, and their applications to the various segments of the gut and the many types of disease that afflict it are presented. The contributors are highly respected leaders in their fields, and the editor has been recognized as one of the foremost innovators in gastrointestinal radiology.

Modern Immunosuppressives (Milestones in Drug Therapy)

Expanding from the classic use of immunosuppressants in transplantation and rejection, this current overview highlights their new roles in clinical medicine. Immunosuppressants are at the forefront of new treatment modalities. Individual chapters focus on their use not only in prevention or treatment of transplant rejection, but also on their use in immune-complex and autoimmune diseases, including rheumatoid arthritis; on combination therapies to achieve synergy in immunosuppression; on new drugs, low molecular weight chemicals, the use of antibodies and gene therapy; on immunological tolerance to prevent or inhibit transplant rejection; and how data derived from transplant studies can be applied to other avenues of immunosuppression. Clinicians and researchers will appreciate the scope of the work and the presentation of new approaches in the rapidly developing field of immunosuppression.

Modern Industrial Microbiology and Biotechnology

The field of industrial microbiology involves a thorough knowledge of the microbial physiology behind the processes in the large-scale, profit-oriented production of microbe-related goods which are the subject of the field. In recent times a paradigm shift has occurred, and a molecular understanding of the various processes by which plants, animals and microorganisms are manipulated is now central to industrial microbiology. Thus the various applications of industrial microbiology are covered broadly, with emphasis on the physiological and genomic principles behind these applications. Relevance of the new elements such as bioinformatics, genomics, proteomics, site-directed mutation and metabolic engineering, which have necessitated the paradigm shift in industrial microbiology are discussed.

Modern Industrial Microbiology and Biotechnology

The field of industrial microbiology involves a thorough knowledge of the microbial physiology behind the processes in the large-scale, profit-oriented production of microbe-related goods which are the subject of the field. In recent times a paradigm shift has occurred, and a molecular understanding of the various processes by which plants, animals and microorganisms are manipulated is now central to industrial microbiology. Thus the various applications of industrial microbiology are covered broadly, with emphasis on the physiological and genomic principles behind these applications. Relevance of the new elements such as bioinformatics, genomics, proteomics, site-directed mutation and metabolic engineering, which have necessitated the paradigm shift in industrial microbiology are discussed.

Modern Infectious Disease Epidemiology

Highly practical yet authoritative, the new edition of Modern Infectious Disease Epidemiology has been thoroughly updated and revised in line with changing health concerns. This successful book continues to outline the tools available to the infectious disease student or clinician seeking a thorough background in the epidemiology of infectious and communicable diseases. Building on many case studies and practical scenarios included, the book then uses the tools learnt to illustrate the fundamental concepts of the study of infectious diseases, such as infection spread, surveillance and control, infectivity, incubation periods, seroepidemiology, and immunity in populations. New edition of this popular book, completely revised and updated Retains the clarity and down-to-earth approach praised in previous editions Successfully combines epidemiological theory with the principles of infectious disease treatment and control A highly experienced author brings a personal and unique approach to this important subject All students of epidemiology, infectious disease medicine and microbiology will find this text invaluable, ensuring its continued popularity.

Modern Infectious Disease Epidemiology

Highly practical yet authoritative, the new edition of Modern Infectious Disease Epidemiology has been thoroughly updated and revised in line with changing health concerns. This successful book continues to outline the tools available to the infectious disease student or clinician seeking a thorough background in the epidemiology of infectious and communicable diseases. Building on many case studies and practical scenarios included, the book then uses the tools learnt to illustrate the fundamental concepts of the study of infectious diseases, such as infection spread, surveillance and control, infectivity, incubation periods, seroepidemiology, and immunity in populations. New edition of this popular book, completely revised and updated Retains the clarity and down-to-earth approach praised in previous editions Successfully combines epidemiological theory with the principles of infectious disease treatment and control A highly experienced author brings a personal and unique approach to this important subject All students of epidemiology, infectious disease medicine and microbiology will find this text invaluable, ensuring its continued popularity.

Modern Infectious Disease Epidemiology: Concepts, Methods, Mathematical Models, and Public Health (Statistics for Biology and Health)

Hardly a day goes by without news headlines concerning infectious disease threats. Currently the spectre of a pandemic of influenza A|H1N1 is raising its head, and heated debates are taking place about the pro’s and con’s of vaccinating young girls against human papilloma virus. For an evidence-based and responsible communication of infectious disease topics to avoid misunderstandings and overreaction of the public, we need solid scientific knowledge and an understanding of all aspects of infectious diseases and their control. The aim of our book is to present the reader with the general picture and the main ideas of the subject. The book introduces the reader to methodological aspects of epidemiology that are specific for infectious diseases and provides insight into the epidemiology of some classes of infectious diseases characterized by their main modes of transmission. This choice of topics bridges the gap between scientific research on the clinical, biological, mathematical, social and economic aspects of infectious diseases and their applications in public health. The book will help the reader to understand the impact of infectious diseases on modern society and the instruments that policy makers have at their disposal to deal with these challenges. It is written for students of the health sciences, both of curative medicine and public health, and for experts that are active in these and related domains, and it may be of interest for the educated layman since the technical level is kept relatively low.

Modern Inhalation Anesthetics (Handbook of Experimental Pharmacology #30)

With contributions by numerous experts

Modern Issues and Methods in Biostatistics (Statistics for Biology and Health)

Classic biostatistics, a branch of statistical science, has as its main focus the applications of statistics in public health, the life sciences, and the pharmaceutical industry. Modern biostatistics, beyond just a simple application of statistics, is a confluence of statistics and knowledge of multiple intertwined fields. The application demands, the advancements in computer technology, and the rapid growth of life science data (e.g., genomics data) have promoted the formation of modern biostatistics. There are at least three characteristics of modern biostatistics: (1) in-depth engagement in the application fields that require penetration of knowledge across several fields, (2) high-level complexity of data because they are longitudinal, incomplete, or latent because they are heterogeneous due to a mixture of data or experiment types, because of high-dimensionality, which may make meaningful reduction impossible, or because of extremely small or large size; and (3) dynamics, the speed of development in methodology and analyses, has to match the fast growth of data with a constantly changing face. This book is written for researchers, biostatisticians/statisticians, and scientists who are interested in quantitative analyses. The goal is to introduce modern methods in biostatistics and help researchers and students quickly grasp key concepts and methods. Many methods can solve the same problem and many problems can be solved by the same method, which becomes apparent when those topics are discussed in this single volume.

Modern Keratoplasty: Surgical Techniques and Indications (Essentials in Ophthalmology)

​Keratoplasty techniques have evolved in the last 15 years into a variety of forms, which have diversified the previous monographic presence of the penetrating keratoplasty technique. The development of anterior lamellar graft (DALK), and posterior lamellar graft (DSAEK), makes an important change in the approach to lamellar surgery. Later on, the appearance of DMEK and superficial lamellar keratectomy broadened the spectrum. Today, intralamellar surgery has evolved with a number of techniques that involve stromal enhancement with biologically active or acellular corneal laminas from donors, customized lenticles from SMILE surgeries or customized by corneal topography, and more recently, corneal regeneration of the stroma by advanced techniques using mesenchymal stem cells.This book offers a comprehensive overview of modern keratoplasty techniques, the technology, surgical skills, and outcomes. It highlights the practical uses of keratoplasty for all cornea surgeons and anterior segment surgeons. The book is divided into sections, each covering a specific type of keratoplasty, including chapters on innovations within each surgery type. The goal of this book is to unify all recent knowledge about the different keratoplasty techniques and outcomes, creating a one-stop resource for ophthalmaolgy surgeons.Modern Keratoplasty is a must-have resource for corneal specialists and surgeons, anterior segment surgeons, refractive surgeons, cataract surgeons, residents, fellows, and corneal researchers.

Modern Magnetic Resonance: Part 1: Applications in Chemistry, Biological and Marine Sciences, Part 2: Applications in Medical and Pharmaceutical Sciences, Part 3: Applications in Materials Science and Food Science

A comprehensive collection of the applications of Nuclear Magnetic Resonance (NMR), Magnetic Resonance Imaging (MRI) and Electron-Spin Resonance (ESR). Covers the wide ranging disciplines in which these techniques are used:* Chemistry;* Biological Sciences;* Pharmaceutical Sciences;* Medical uses;* Marine Science;* Materials Science;* Food Science. Illustrates many techniques through the applications described, e.g.:* High resolution solid and liquid state NMR;* Low resolution NMR, especially important in food science;* Solution State NMR, especially important in pharmaceutical sciences;* Magnetic Resonance Imaging, especially important for medical uses;* Electron Spin Resonance, especially important for spin-labelling in food, marine and medical studies.

Modern Management of Abnormal Uterine Bleeding

Modern Management of Abnormal Uterine Bleeding focuses on helping gynecologists refine their operative techniques and consider new approaches to the diagnosis, and treatment, of this highly challenging condition by investigating: current scientific and clinical trails &nb

Modern Management of Cancer of the Rectum

Modern Management of Cancer of the Rectum is intended to provide a comprehensive overview of all aspects of rectal neoplasms. It addresses epidemiology, biology, screening and chemoprevention, the role of imaging in diagnosis, staging and prognosis, radiation therapy, medical and surgical treatment, as well as new modalities of therapy, including laparoscopy, and transanal endoscopic surgery. A greater understanding of prognostic factors, patterns of spread and natural history has occurred during the past decade; together with new diagnostic modalities this has led to significant changes in the management of patients with rectal cancer. This book will be invaluable for all those who treat rectal cancer.

Modern Management of Cancer of the Rectum

Modern Management of Cancer of the Rectum is intended to provide a comprehensive overview of all aspects of rectal neoplasms. It addresses such topics as epidemiology, biology, screening and chemoprevention, the role of imaging in diagnosis, staging and prognosis, radiation therapy, medical and surgical treatment, as well as new modalities of therapy, including laparoscopy, and transanal endoscopic surgery. A greater understanding of prognostic factors, patterns of spread and natural history has occurred during the past decade; together with new diagnostic modalities this has led to significant changes in the management of patients with rectal cancer. This book will be invaluable for all those who treat rectal cancer.

Modern Management of Endometriosis

Endometriosis - a condition in which the lining of the uterus grows in other abdominal locations - is one of the most common causes of severe period pain, pelvic pain, and abnormal bleeding in women. Untreated, it may result in long-term complications such as pelvic adhesions, ovarian cysts and infertility. At times, bowel, bladder, and ureters may