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Multimodal Oscillation-based Connectivity Theory

by Satu Palva

Systems-level neuronal mechanisms that coordinate the temporally, anatomically, and functionally distributed neuronal activity into coherent cognitive operations in the human brain have remained poorly understood. In humans, neuronal oscillations and synchronization can be recorded non-invasively with electro- and magnetoencephalography (EEG and MEG) that have excellent temporal resolution and an adequate spatial resolution when combined with source-reconstruction methods. In this book, leading authors in the field describe how recent methodological advances have paved the way to several major breakthroughs in the observations of large-scale synchrony from human non-invasive MEG data. This volume also presents the caveats influencing analyses of synchronization. These include the non-homogeneous sensitivity of MEG to superficial cortical sources, and, most importantly, the multitude of consequences of linear mixing. Linear mixing is an immense confounder in the sensor-level analyses of synchronization, but is also present at the source level. Approaches that can be used to avoid or compensate for these issues are then discussed. Thereafter, several authors take up a number of the functional roles that large-scale synchronization has in cognition. The authors assess how the spatio–temporal and –spectral organization and strength of both local and large-scale synchronized networks are associated with conscious sensory perception, visual working memory functions, and attention. These chapters summarize several lines of research showing how the strength of local and inter-areal oscillations in both cortical and subcortical brain structures is correlated with cognitive functions. Together these data suggest that synchronized neuronal oscillations may be a systems-level neuronal mechanism underlying the coordination of distributed processing in human cognition. In line with this argument, other authors go on to describe how oscillations and synchronization are altered in clinical populations, complementing the data presented on healthy subjects. Importantly, this book includes chapters from authors using many different approaches to the analyses of neuronal oscillations, ranging from local oscillatory activities to the usage of graph theoretical tools in the analyses of synchronization. In this way the present volume provides a comprehensive view on the analyses and functional significance of neuronal oscillations in humans. This book is aimed at doctoral and post-doctoral students as well as research scientists in the fields of cognitive neuroscience, psychology, medicine, and neurosciences.

Multimodal Retrieval in the Medical Domain: First International Workshop, MRMD 2015, Vienna, Austria, March 29, 2015, Revised Selected Papers (Lecture Notes in Computer Science #9059)

by Henning Müller Oscar Alfonso Jimenez del Toro Allan Hanbury Georg Langs Antonio Foncubierta Rodriguez

This book constitutes the proceedings of the First International Workshop on Multimodal Retrieval in the Medical Domain, MRMD 2015, held in Vienna, Austria, on March 29, 2015. The workshop was held in connection with ECIR 2015. The 14 full papers presented, including one invited paper, a workshop overview and five papers on the VISCERAL Retrieval Benchmark, were carefully reviewed and selected from 18 submissions. The papers focus on the following topics: importance of data other than text for information retrieval; semantic data analysis; scalability approaches towards big data sets.

Multimodal Sentiment Analysis (Socio-affective Computing Ser. #8)

by Soujanya Poria Amir Hussain Erik Cambria

This latest volume in the series, Socio-Affective Computing, presents a set of novel approaches to analyze opinionated videos and to extract sentiments and emotions. Textual sentiment analysis framework as discussed in this book contains a novel way of doing sentiment analysis by merging linguistics with machine learning. Fusing textual information with audio and visual cues is found to be extremely useful which improves text, audio and visual based unimodal sentiment analyzer. This volume covers the three main topics of: textual preprocessing and sentiment analysis methods; frameworks to process audio and visual data; and methods of textual, audio and visual features fusion. The inclusion of key visualization and case studies will enable readers to understand better these approaches. Aimed at the Natural Language Processing, Affective Computing and Artificial Intelligence audiences, this comprehensive volume will appeal to a wide readership and will help readers to understand key details on multimodal sentiment analysis.

Multimodal Treatment of Recurrent Pelvic Colorectal Cancer (Updates in Surgery #0)

by Giovanni Maria Romano

This book analyzes all aspects of modern multimodal treatment of locally recurrent rectal cancer in the pelvis in order to offer a panoramic overview of the different therapeutic options and enable the reader to balance their benefits and drawbacks. Indications for surgery and the surgical techniques themselves, including reconstruction techniques after major exenterative surgery, are clearly described and evaluated. The role of new imaging tools, such as MRI and PET-CT, in staging recurrences and guiding therapy is assessed and detailed consideration is given to the use of neoadjuvant and iterative radiotherapy and the indications for systemic chemotherapy. Morbidity, mortality, oncologic outcomes, and quality of life issues are carefully analyzed and options for pain control and palliation are examined. Finally, a national survey is presented on the state of the art in the surgical treatment of locally recurrent rectal cancer in Italy. While there has been a dramatic fall in the incidence of local pelvic recurrences, their treatment remains a major clinical challenge which requires a multidisciplinary approach and careful selection of the most appropriate strategy in each case. This book will aid practitioners in making the correct decisions in individual patients.

Multimodality Imaging: For Intravascular Application

by Qifa Zhou Zhongping Chen

This book provides a state-of-the-art overview of the combined use of imaging modalities to obtain important functional and morphological information on intravascular disease and enhance disease detection. It discusses the integration of intravascular ultrasound (IVUS, intravascular optical coherence tomography (OCT), intravascular photoacoustic imaging (IVPA) and acoustic radiation force optical coherence elastography (ARF-OCE), and introduces the integration of multimodality imaging systems, such as IR and florescence. It includes the latest research advances and numerous imaging photos to offer readers insights into current intravascular applications. It is a valuable resource for students, scientists and physicians wanting to gain a deeper understanding of multimodality imaging tools.

Multimodality Imaging and Intervention in Oncology

by Emanuele Neri Paola Anna Erba

This book provides the reader with a focused review of multimodality imaging strategies (radiology and molecular imaging) in staging and re-staging the major types of cancer (i.e. thyroid, breast, colon-rectum, lung, prostate, pancreas, liver, head and neck, and hematological cancer), including rare neoplasms. In addition to presenting the possible diagnostic pathways for all oncologic diseases, the book identifies those interventions currently available in clinical practice (these being a branch of interventional radiology), while also examining and detailing molecular radiotherapy strategies. The work has an interdisciplinary appeal and, thanks to its highly informative and cutting-edge coverage, professionals as well as advanced students and residents in radiology, oncology and surgery will find it of particular interest.

Multimodality Imaging for Cardiac Valvular Interventions, Volume 1 Aortic Valve: From Diagnosis to Decision-Making

by Francesco Maisano Philipp Kaufmann Hatem Alkadhi Michel Zuber Alberto Pozzoli Edwin Ho

This book provides a practically applicable guide to the use of multimodality imaging for managing aortic valve disorders. Details of how to successfully diagnose a range of aortic valve diseases is presented, with detailed information covered on the techniques and relevant criteria for pre-operative screening, surgical and transcatheter planning, intraprocedural imaging and related postoperative follow-up. Multimodality Imaging for Cardiac Valvular Interventions, Volume 1 Aortic Valve: From Diagnosis to Decision-Making enables the reader to develop a thorough understanding and confidence of how to make appropriate clinical decisions when confronted by a range of aortic valve diseases. It is therefore a key resource for practicing cardiac imagers, cardiologists and interventional cardiologists who encounter these patients in their day-to-day clinical practice and trainees in cardiology seeking insight on the appropriate management of these patients.

Multimodality Imaging for Transcatheter Aortic Valve Replacement

by James K. Min Daniel S. Berman Jonathon Leipsic

This book is ideal for cardiovascular imagers of all backgrounds as well as proceduralists (surgeons and interventional cardiologists) performing TAVR. This text is also of value for the physicians and nurses involved in the care of these patients, and for fellows-in-training. This practical text brings together guidance on using multi-modality imaging in one book and highlights its usage with a focus on patient care. Pre-procedural, Intra-procedural and Long-term follow up), this review offers expert opinion and evidence-based guidance on how to incorporate the various imaging modalities at each step in the care of a TAVR patient. Although much has been learned in the short span of time since TAVR was introduced into the field, our book will also offer recommendations for clinically-relevant research areas that will lead to best practice strategies for incorporating multi-modality imaging into TAVR patient care.

Multimodality Imaging Guidance in Interventional Pain Management

by Samer N. Narouze

Multimodality Imaging Guidance for Interventional Pain Management is a comprehensive resource that covers fluoroscopy-guided procedures, ultrasound interventions, and computed tomography (CT)-guided procedures used in interventional pain management. Fluoroscopy-guided procedures have been the standard of care for many years and are widely available and affordable. Due to the lack of radiation exposure and the ability to see various soft tissue structures, ultrasound-guided interventions are more precise and safer. Primarily performed by radiologists, the benefits, disadvantages, and basic techniques of CT-guided procedures are also included in the volume. By covering all imaging modalities, Multimodality Imaging Guidance for Interventional Pain Management allows for an efficient comparison of the capabilities of each modality.

Multimodality Imaging Innovations In Adult Congenital Heart Disease: Emerging Technologies and Novel Applications (Congenital Heart Disease in Adolescents and Adults)

by Pastora Gallego Israel Valverde

This book focuses on congenital heart disease (CHD) and emerging imaging technologies. It covers all clinically relevant aspects of the fascinating new cardiac imaging technologies, including a comprehensive explanation of their basic principles, practical aspects of novel clinical applications, and detailed descriptions of specific uses in the broad spectrum of clinically important adult CHD. Innovations and emerging technologies for diagnosis and therapeutics, evaluation and treatment are continually evolving, and due to these advances in non-invasive diagnosis, there has been a significant improvement in the survival rates for CHD patient. Novel approaches to trans-catheter interventions and advances in echocardiography, MRI and CT imaging are being developed and incorporated into routine clinical practice, while emerging three-dimensional printing technologies are fundamentally affecting patient care, research, trainee education, and interactions between multidisciplinary teams, patients, and caregivers. In addition, translational technologies on the horizon promise to take this nascent field even further. Exploring the applicability of these emerging technologies in improving our understanding of complex congenital cardiac defect anatomy and physiology will provide new treatment options for this unique population. Written by experts in the field who are also involved in patient care, this book discusses the practical application of innovations in advanced multimodality imaging in the daily clinical routine and offers tips and tricks for beginners.

Multimodality Management of Borderline Resectable Pancreatic Cancer

by Matthew H.G. Katz Syed A. Ahmad

This volume provides the most comprehensive coverage of clinical management of borderline resectable pancreatic cancer available. Authored by leaders in the field, the book focuses on current clinical management of this disease stage, the importance of multimodality treatment algorithms, and an interdisciplinary approach to care. Surgical chapters are well-illustrated to provide surgeons and surgical trainees with important technical pearls. Clinical trials and trial design are also discussed.Multimodality Management of Borderline Resectable Pancreatic Cancer is a valuable resource for gastroenterologists, medical oncologists, radiation oncologists, surgical oncologists, general surgeons, and trainees interested in the treatment of pancreatic cancer.

Multimodality Therapy for Gastric Cancer: Appendix: Database of the Cancer Institute Hospital

by Cancer Institute Hospital

Recent clinical trials of adjuvant therapy for gastric cancer in Japan have shown improved survival benefits, but the results have been considered controversial and have been viewed with some skepticism in the West. Until now, the efforts of Japanese surgical oncologists in multimodality therapy have not been fully understood because they have not been adequately reported in English. This volume now presents the experience and expertise of Japanese surgeons who utilize preoperative or intraoperative chemotherapy, or a combination of systemic and regional chemotherapy. Their collected work provides valuable insight in the Japanese perspective and success in treating gastric cancer. Included in the appendix is an extensive tabular analysis of the gastric cancer database at the Cancer Institute Hospital of Tokyo. Probably the largest such database in the world from a single institution, the analyses present the state of the art in treatment of gastric cancer.

Multiobjective Optimization Algorithms for Bioinformatics

by Ujjwal Maulik Sanghamitra Bandyopadhyay Anirban Mukhopadhyay Sumanta Ray

This book provides an updated and in-depth introduction to the application of multiobjective optimization techniques in bioinformatics. In particular, it presents multiobjective solutions to a range of complex real-world bioinformatics problems. The authors first provide a comprehensive yet concise and self-contained introduction to relevant preliminary methodical constructions such as genetic algorithms, multiobjective optimization, data mining and several challenges in the bioinformatics domain. This is followed by several systematic applications of these techniques to real-world bioinformatics problems in the areas of gene expression and network biology. The book also features detailed theoretical and mathematical notes to facilitate reader comprehension. The book offers a valuable asset for a broad range of readers – from undergraduate to postgraduate, and as a textbook or reference work. Researchers and professionals can use the book not only to enrich their knowledge of multiobjective optimization and bioinformatics, but also as a comprehensive reference guide to applying and devising novel methods in bioinformatics and related domains.

Multiorgan Procurement for Transplantation: A Guide To Surgical Technique And Management

by Paolo Aseni Antonino M. Grande Luciano Carlis

This well-illustrated handbook provides answers to important questions that may arise during the retrieval of multiple organs for transplantation and offers step-by-step descriptions of current surgical techniques for procurement of the various thoracic and abdominal organs, including heart, lung, liver, intestine, pancreas, and kidney. The coverage includes detailed instruction on liver splitting techniques and on living donor liver hepatectomies and laparoscopic and robot-assisted nephrectomy for transplantation. In addition, guidance is provided on preoperative evaluation for multiorgan donation, contraindications, management for organ retrieval in deceased donors, and organ preservation. The advice offered and the questions addressed will be of relevance not only to transplant surgeons, trainees, and fellows but also to all other professionals involved in organ transplantation, including nursing staff in intensive care units and emergency rooms.

Multiorganversagen: (10. Wiener Intensivmedizinische Tage, 21.–22. Februar 1992) (Intensivmedizinisches Seminar #4)

by Erwin Deutsch Bruno Schneeweiß Jörg Slany Gunther Kleinberger Kurt Lenz Rudolf Ritz Hans-Peter Schuster Georg Simbruner

Das Multiorganversagen stellt eine der größten Herausforderungen in der Intensivmedizin dar. Aufgrund ausgedehnter Forschungstätigkeit konnten in den letzten Jahren neue Erkenntnisse in der Entstehung dieses bedrohlichen Krankheitsbildes und in dessen Beherrschung gewonnen werden. Hauptthema der 10. Wiener Intensivmedizinischen Tage war daher das Multiorganversagen, dessen wichtigste Referate im vorliegenden vierten Band des Intensivmedizinischen Seminars präsentiert werden. Im ersten Teil wird auf mögliche Ursachen wie Sepsis und Polytrauma eingegangen, wobei in einem eigenen Kapitel das Versagen der Zelle im Rahmen dieses Krankheitsbildes dargestellt wird. Der zweite Teil behandelt das Versagen der einzelnen Organe im Rahmen des Multiorganversagens. Im dritten Teil werden die Überwachungsmöglichkeiten von Organfunktionen und deren klinische Relevanz diskutiert, und schließlich wird im letzten Teil des Buches auf die Therapie des Patienten im Multiorganversagen eingegangen.

Multiparametric Ultrasound Diagnosis of Breast Diseases

by Gennady T. Sukhikh Alexander N. Sencha

This richly illustrated book provides a comprehensive overview of the use of current ultrasound techniques, including contrast-enhanced ultrasound and ultrasonic elastography, in the diagnosis of breast disease. The advantages and pitfalls of the various imaging modalities are identified, and it is explained how combined use of the modalities – multiparametric ultrasound – aids diagnosis and in particular assists in the differentiation of benign and malignant disease. Readers will find detailed description and illustration of the imaging appearances of age-related features (including in children and adolescents), the most important benign diseases, different forms of breast cancer, mammary gland pathology in the contexts of pregnancy and female reproductive system disease, chest gland pathology in males, and recurrent and metastatic disease. In addition, ultrasound-guided breast interventions and imaging of breast implants are discussed. Specialists in ultrasound diagnostics, radiologists, oncologists, and surgeons will all find this topical book to be both interesting and helpful in daily clinical practice.

Multiparametric Ultrasound for the Assessment of Diffuse Liver Disease - E-Book: A Practical Approach

by Richard G. Barr Giovanna Ferraioli

For those who treat and diagnose liver disease, whether radiologists, emergency medical physicians, hepatologists, or sonographers, a clear understanding of the strict protocol needed to obtain accurate measurements is essential. Multiparametric Ultrasound for the Assessment of Diffuse Liver Disease offers a practical approach to liver shear wave elastography acquisition from globally recognized leaders in the field. It answers critical questions such as how to use each of the current techniques to best characterize your patients' liver disease, how to deal with the limitations of each of these techniques, and what to ask—and not to ask—of your devices and software. - Presents an overview of conventional ultrasound findings in chronic liver disease and portal hypertension, and presents the basic concepts and protocols needed to measure liver stiffness and interpret liver stiffness values. - Details clinical applications, artifacts, and guidelines of liver ultrasound elastography, including tips and tricks. - Reviews the latest ultrasound techniques to assess liver steatosis and focal liver lesions, as well as the uses of new technologies of fat quantification and dispersion.

Multiparticulate Drug Delivery: Formulation, Processing and Manufacturing (Advances in Delivery Science and Technology)

by Ali R. Rajabi-Siahboomi

Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery. The book will cover market trends, potential benefits and formulation challenges for various types of multiparticulate systems. Drug solubility, dose, chemistry and therapeutic indications as well as excipient suitability coupled with manufacturing methods will be fully covered. Key approaches for taste-masking, delayed release and extended release of multiparticulates systems are of significant interest, especially their in-vivo and in-vitro performance. In addition, the principles of scale-up, QbD, and regulatory aspects of common materials used in this technology will be explained, as well as recent advances in materials and equipment enabling robust, flexible and cost-effective manufacture. Case studies illustrating best practices will also make the book a valuable resource to pharmaceutical scientists in industry and academia.

Multipele sclerose in beeld

by G.J.D. Hengstman

Multipele sclerose (MS) is de meest voorkomende neurologisch aandoening op de jongvolwassen leeftijd leidend tot blijvende invaliditeit. In het afgelopen decennium zijn de mogelijkheden om MS te behandelen sterk toegenomen. Met de toename van de behandelmogelijkheden worden ook de afwegingen die gemaakt moeten worden ten aanzien van bijvoorbeeld het starten van medicatie, het monitoren van de bijwerkingen en het veranderen of stoppen van de medicatie complexer. MS in beeld is geschreven door medisch professionals,betrokken bij de geneeskundige zorg van patiënten met MS. In de 25 patiëntbeschrijvingen worden diverse aspecten besproken: van diagnose tot multidisciplinaire netwerken, van eenvoudige behandelingen tot complexe bijwerkingen. MS in beeld geeft een illustratie van de praktische problemen en dilemma's van de dagelijkse MS-zorg. Het eerste deel van het boek bevat de patiëntpresentaties en de vragen. De antwoorden en de verdere uitwerking hiervan zijn in het tweede deel terug te vinden.

Multiphoton Microscopy (Neuromethods #148)

by Espen Hartveit

This volume covers the latest techniques and strategies used in multi-photon excitation (MPE) microscopy. Chapters in this book cover the fundamentals of MPE microscopy as applied to both in vitro and in vivo experimental systems; information on how to combine MPE microscopy with targeted electrophysiological recordings, calcium imaging, and transmembrane voltage imaging; methods to investigate cellular and large-scale neural morphology; signaling in astrocytes; and ways to use MPE microscopy to study the retina. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.Comprehensive and thorough, Multiphoton Microscopy is a valuable resource for both expert and novice researchers interested in expanding their knowledge and research in this rapidly developing field.

Multiple Analyses in Clinical Trials: Fundamentals for Investigators (Statistics for Biology and Health)

by Lemuel A. Moyé

Concentrating on the rationale for the analyses, the difficulties posed by their interpretation, easily understood solutions, and useful problem sets, this book will help clinical investigators understand multiple analysis procedures and key issues. It is written for advanced medical students, clinical investigators at all levels, research groups within the pharmaceutical industry, regulators at the local, state, and federal level, and biostatisticians.

Multiple Biological Sequence Alignment: Scoring Functions, Algorithms and Evaluation (Wiley Series in Bioinformatics)

by Ken Nguyen Xuan Guo Yi Pan

Covers the fundamentals and techniques of multiple biological sequence alignment and analysis, and shows readers how to choose the appropriate sequence analysis tools for their tasks This book describes the traditional and modern approaches in biological sequence alignment and homology search. This book contains 11 chapters, with Chapter 1 providing basic information on biological sequences. Next, Chapter 2 contains fundamentals in pair-wise sequence alignment, while Chapters 3 and 4 examine popular existing quantitative models and practical clustering techniques that have been used in multiple sequence alignment. Chapter 5 describes, characterizes and relates many multiple sequence alignment models. Chapter 6 describes how traditionally phylogenetic trees have been constructed, and available sequence knowledge bases can be used to improve the accuracy of reconstructing phylogeny trees. Chapter 7 covers the latest methods developed to improve the run-time efficiency of multiple sequence alignment. Next, Chapter 8 covers several popular existing multiple sequence alignment server and services, and Chapter 9 examines several multiple sequence alignment techniques that have been developed to handle short sequences (reads) produced by the Next Generation Sequencing technique (NSG). Chapter 10 describes a Bioinformatics application using multiple sequence alignment of short reads or whole genomes as input. Lastly, Chapter 11 provides a review of RNA and protein secondary structure prediction using the evolution information inferred from multiple sequence alignments. • Covers the full spectrum of the field, from alignment algorithms to scoring methods, practical techniques, and alignment tools and their evaluations • Describes theories and developments of scoring functions and scoring matrices •Examines phylogeny estimation and large-scale homology search Multiple Biological Sequence Alignment: Scoring Functions, Algorithms and Applications is a reference for researchers, engineers, graduate and post-graduate students in bioinformatics, and system biology and molecular biologists. Ken Nguyen, PhD, is an associate professor at Clayton State University, GA, USA. He received his PhD, MSc and BSc degrees in computer science all from Georgia State University. His research interests are in databases, parallel and distribute computing and bioinformatics. He was a Molecular Basis of Disease fellow at Georgia State and is the recipient of the highest graduate honor at Georgia State, the William M. Suttles Graduate Fellowship. Xuan Guo, PhD, is a postdoctoral associate at Oak Ridge National Lab, USA. He received his PhD degree in computer science from Georgia State University in 2015. His research interests are in bioinformatics, machine leaning, and cloud computing. He is an editorial assistant of International Journal of Bioinformatics Research and Applications. Yi Pan, PhD, is a Regents' Professor of Computer Science and an Interim Associate Dean and Chair of Biology at Georgia State University. He received his BE and ME in computer engineering from Tsinghua University in China and his PhD in computer science from the University of Pittsburgh. Dr. Pan's research interests include parallel and distributed computing, optical networks, wireless networks and bioinformatics. He has published more than 180 journal papers with about 60 papers published in various IEEE/ACM journals. He is co-editor along with Albert Y. Zomaya of the Wiley Series in Bioinformatics.

Multiple Biological Sequence Alignment: Scoring Functions, Algorithms and Evaluation (Wiley Series in Bioinformatics)

by Yi Pan Ken Nguyen Xuan Guo

Covers the fundamentals and techniques of multiple biological sequence alignment and analysis, and shows readers how to choose the appropriate sequence analysis tools for their tasks This book describes the traditional and modern approaches in biological sequence alignment and homology search. This book contains 11 chapters, with Chapter 1 providing basic information on biological sequences. Next, Chapter 2 contains fundamentals in pair-wise sequence alignment, while Chapters 3 and 4 examine popular existing quantitative models and practical clustering techniques that have been used in multiple sequence alignment. Chapter 5 describes, characterizes and relates many multiple sequence alignment models. Chapter 6 describes how traditionally phylogenetic trees have been constructed, and available sequence knowledge bases can be used to improve the accuracy of reconstructing phylogeny trees. Chapter 7 covers the latest methods developed to improve the run-time efficiency of multiple sequence alignment. Next, Chapter 8 covers several popular existing multiple sequence alignment server and services, and Chapter 9 examines several multiple sequence alignment techniques that have been developed to handle short sequences (reads) produced by the Next Generation Sequencing technique (NSG). Chapter 10 describes a Bioinformatics application using multiple sequence alignment of short reads or whole genomes as input. Lastly, Chapter 11 provides a review of RNA and protein secondary structure prediction using the evolution information inferred from multiple sequence alignments. • Covers the full spectrum of the field, from alignment algorithms to scoring methods, practical techniques, and alignment tools and their evaluations • Describes theories and developments of scoring functions and scoring matrices •Examines phylogeny estimation and large-scale homology search Multiple Biological Sequence Alignment: Scoring Functions, Algorithms and Applications is a reference for researchers, engineers, graduate and post-graduate students in bioinformatics, and system biology and molecular biologists. Ken Nguyen, PhD, is an associate professor at Clayton State University, GA, USA. He received his PhD, MSc and BSc degrees in computer science all from Georgia State University. His research interests are in databases, parallel and distribute computing and bioinformatics. He was a Molecular Basis of Disease fellow at Georgia State and is the recipient of the highest graduate honor at Georgia State, the William M. Suttles Graduate Fellowship. Xuan Guo, PhD, is a postdoctoral associate at Oak Ridge National Lab, USA. He received his PhD degree in computer science from Georgia State University in 2015. His research interests are in bioinformatics, machine leaning, and cloud computing. He is an editorial assistant of International Journal of Bioinformatics Research and Applications. Yi Pan, PhD, is a Regents' Professor of Computer Science and an Interim Associate Dean and Chair of Biology at Georgia State University. He received his BE and ME in computer engineering from Tsinghua University in China and his PhD in computer science from the University of Pittsburgh. Dr. Pan's research interests include parallel and distributed computing, optical networks, wireless networks and bioinformatics. He has published more than 180 journal papers with about 60 papers published in various IEEE/ACM journals. He is co-editor along with Albert Y. Zomaya of the Wiley Series in Bioinformatics.

Multiple Choice Questions for Haematology and Core Medical Trainees

by Barbara J. Bain

Written to help haematology and general medical trainees evaluate their own knowledge, and particularly useful for those preparing for the Part 1 examination of the Royal College of Pathologists. This exam-centered book will also be of use to core medical trainees preparing for the examinations of the Royal College of Physicians and the Royal Australasian College of Physicians and to haematology and general medicine trainees in other countries where methods of examination are similar. The 150 questions are presented in two formats, Single Best Answer and Extended Matching Question, and comes complete with detailed feedback and, when appropriate, relevant references are given for each question so that those who select the wrong answer will understand why another answer is better. Quick reference question book, ideal for examination preparation Includes 50 SBA questions, ideal for the Part 1 and Part 2 MRCP examinations, which although having a general medical slant, are also appropriate for haematology specialist trainees Includes 70 SBA multiple choice questions appropriate for haematology specialist trainees but also useful to core medical trainees Includes 30 EMQs suitable for those taking Part 1 of the FRCPath examination Questions come complete with fully referenced answers and discussion points This book provides an educational tool for training as well as an ideal way to prepare for examinations and is also of value to those who examine in haematology and haematopathology.

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