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Biostatistics and Epidemiology: A Primer for Health and Biomedical Professionals
by Sylvia Wassertheil-Smoller Jordan SmollerSince the publication of the first edition, Biostatistics and Epidemiology has attracted loyal readers from across specialty areas in the biomedical community. Not only does this textbook teach foundations of epidemiological design and statistical methods, but it also includes topics applicable to new areas of research. Areas covered in the fourth edition include a new chapter on risk prediction, risk reclassification and evaluation of biomarkers, new material on propensity analyses, and a vastly expanded chapter on genetic epidemiology, which is particularly relevant to those who wish to understand the epidemiological and statistical aspects of scientific articles in this rapidly advancing field. Biostatistics and Epidemiology was written to be accessible for readers without backgrounds in mathematics. It provides clear explanations of underlying principles, as well as practical guidelines of "how to do it" and "how to interpret it." Key features include a philosophical and logical explanation at the beginning of the book, subsections that can stand alone or serve as reference, cross-referencing, recommended reading, and appendices covering sample calculations for various statistics in the text.
Biostatistics and Microbiology: A Survival Manual
by Daryl S. PaulsonThis "nuts and bolts" book provides a condensation of biostatistical methods that applied microbiology researchers need to perform data analyses. Based on the author’s more than two decades of applied research and teaching experience, it is presented in a straight-forward manner, applicable by practicing microbiologists with minimal backgrounds in mathematics. All methods rely only on the use of a basic hand-held calculator. The overriding goal of this book is to ground one’s microbiological expertise and experience in one’s research pursuits, using biostatistics not as a black box, but as a tool.
The Biostatistics Cookbook: The Most User-Friendly Guide for the Bio/Medical Scientist
by S. Michelson T. SchofieldWe live in a very uncertain world. Variation surrounds our work. There is noise in our experiments, in our measurements, and in our test subjects. From all these sources of uncertainty and variation, we try to extract a coherent picture of very complex and sometimes dynamic, biological and chemical processes. In fact, one of our major challenges is to separate this signal, the 'real' biology or chemistry, from the noise. The tools developed to do this are called, collectively, biostatistics. Any tool, even a hammer, can be misused. This could result, at best, in inefficiency, and, at worst, in disaster. With the advent of newer, us- friendly statistical software packages, desk top computing, and point-a- click technologies, it is easier than ever to make mistakes in your analyses. The beauty of having access to so much computing power is that you can now enjoy ultimate flexibility in data processing: that can also be a problem. Ask your computer to produce a particular analysis, report or graphic, and that is exactly what you will get: if you happen to have asked for the wrong thing it will be produced just as quickly, and you will probably never know it was wrong. One aim of this handbook is to help you choose the correct tool for the job at hand, understand its strengths and weaknesses, and to help you recognize when you should seek expert advice. We describe biostatistics as a collection of tools for very good reasons.
Biostatistics Decoded
by A. Gouveia OliveiraStudy design and statistical methodology are two important concerns for the clinical researcher. This book sets out to address both issues in a clear and concise manner. The presentation of statistical theory starts from basic concepts, such as the properties of means and variances, the properties of the Normal distribution and the Central Limit Theorem and leads to more advanced topics such as maximum likelihood estimation, inverse variance and stepwise regression as well as, time-to-event, and event-count methods. Furthermore, this book explores sampling methods, study design and statistical methods and is organized according to the areas of application of each of the statistical methods and the corresponding study designs. Illustrations, working examples, computer simulations and geometrical approaches, rather than mathematical expressions and formulae, are used throughout the book to explain every statistical method. Biostatisticians and researchers in the medical and pharmaceutical industry who need guidance on the design and analyis of medical research will find this book useful as well as graduate students of statistics and mathematics with an interest in biostatistics. Biostatistics Decoded: Provides clear explanations of key statistical concepts with a firm emphasis on practical aspects of design and analysis of medical research. Features worked examples to illustrate each statistical method using computer simulations and geometrical approaches, rather than mathematical expressions and formulae. Explores the main types of clinical research studies, such as, descriptive, analytical and experimental studies. Addresses advanced modeling techniques such as interaction analysis and encoding by reference and polynomial regression.
Biostatistics Decoded
by A. Gouveia OliveiraStudy design and statistical methodology are two important concerns for the clinical researcher. This book sets out to address both issues in a clear and concise manner. The presentation of statistical theory starts from basic concepts, such as the properties of means and variances, the properties of the Normal distribution and the Central Limit Theorem and leads to more advanced topics such as maximum likelihood estimation, inverse variance and stepwise regression as well as, time-to-event, and event-count methods. Furthermore, this book explores sampling methods, study design and statistical methods and is organized according to the areas of application of each of the statistical methods and the corresponding study designs. Illustrations, working examples, computer simulations and geometrical approaches, rather than mathematical expressions and formulae, are used throughout the book to explain every statistical method. Biostatisticians and researchers in the medical and pharmaceutical industry who need guidance on the design and analyis of medical research will find this book useful as well as graduate students of statistics and mathematics with an interest in biostatistics. Biostatistics Decoded: Provides clear explanations of key statistical concepts with a firm emphasis on practical aspects of design and analysis of medical research. Features worked examples to illustrate each statistical method using computer simulations and geometrical approaches, rather than mathematical expressions and formulae. Explores the main types of clinical research studies, such as, descriptive, analytical and experimental studies. Addresses advanced modeling techniques such as interaction analysis and encoding by reference and polynomial regression.
Biostatistics Decoded
by A. Gouveia OliveiraBiostatistics Decoded covered a large number of statistical methods that are mainly applied to clinical and epidemiological research, as well as a comprehensive discussion of study designs for observational research and clinical trials, two important concerns for the clinical researcher. In this second edition, new material is included covering statistical methods and study designs that are used to analyse research. Following the same methodology used in the first edition, the chapters are presented in two levels of detail, one for the reader who wishes only to understand the rationale behind each statistical method, and one for the reader who wishes to understand the computations Key features include: Extensive coverage of the design and analysis of experiments for basic science research Experimental designs are presented together with the statistical methods The rationale of all forms of ANOVA is explained with simple mathematics A comprehensive presentation of statistical tests for multiple comparisons Calculations for all statistical methods are illustrated with examples and explained step-by-step. This book presents biostatistical concepts and methods in a way that is accessible to anyone, regardless of his or her knowledge of mathematics. The topics selected for this book cover will meet the needs of clinical professionals to readers in basic science research.
Biostatistics Decoded
by A. Gouveia OliveiraBiostatistics Decoded covered a large number of statistical methods that are mainly applied to clinical and epidemiological research, as well as a comprehensive discussion of study designs for observational research and clinical trials, two important concerns for the clinical researcher. In this second edition, new material is included covering statistical methods and study designs that are used to analyse research. Following the same methodology used in the first edition, the chapters are presented in two levels of detail, one for the reader who wishes only to understand the rationale behind each statistical method, and one for the reader who wishes to understand the computations Key features include: Extensive coverage of the design and analysis of experiments for basic science research Experimental designs are presented together with the statistical methods The rationale of all forms of ANOVA is explained with simple mathematics A comprehensive presentation of statistical tests for multiple comparisons Calculations for all statistical methods are illustrated with examples and explained step-by-step. This book presents biostatistical concepts and methods in a way that is accessible to anyone, regardless of his or her knowledge of mathematics. The topics selected for this book cover will meet the needs of clinical professionals to readers in basic science research.
Biostatistics for Animal Science
by Miroslav Kaps William LambersonDesigned to cover techniques for analysis of data in the animal sciences, this popular textbook provides an overview of the basic principles of statistics enabling the subsequent applications to be carried out with familiarity and understanding. Each chapter begins by introducing a problem with practical questions, followed by a brief theoretical background. Most topics are followed up with numerical examples to illustrate the methods described using data-sets from animal sciences and related fields. The same examples are then solved using the SAS software package. Key features of this third edition: - Updated throughout, and covers a wealth of new distributions and new material on non-normal dependent variables - Improved clarity of text and examples - Includes both basic techniques and more complex procedures to provide an essential resource whatever your level - Contains exercises and many worked examples in SAS. Written primarily for students and researchers in animal sciences, the text is also useful for those studying agricultural, biological, and veterinary sciences.
Biostatistics for Clinical and Public Health Research
by Melody S. GoodmanBiostatistics for Clinical and Public Health Research provides a concise overview of statistical analysis methods. Use of SAS and Stata statistical software is illustrated in full, including how to interpret results. Focusing on statistical models without all the theory, the book is complete with exercises, case studies, take-away points, and data sets. Readers will be able to maximize their statistical abilities in hypothesis testing, data interpretation, and application while also learning when and how to consult a biostatistician. This book will be an invaluable tool for students and clinical and public health practitioners.
Biostatistics for Clinical and Public Health Research
by Melody S. GoodmanBiostatistics for Clinical and Public Health Research provides a concise overview of statistical analysis methods. Use of SAS and Stata statistical software is illustrated in full, including how to interpret results. Focusing on statistical models without all the theory, the book is complete with exercises, case studies, take-away points, and data sets. Readers will be able to maximize their statistical abilities in hypothesis testing, data interpretation, and application while also learning when and how to consult a biostatistician. This book will be an invaluable tool for students and clinical and public health practitioners.
Biostatistics For Dummies
by John PezzulloScore your highest in biostatistics Biostatistics is a required course for students of medicine, epidemiology, forestry, agriculture, bioinformatics, and public health. In years past this course has been mainly a graduate-level requirement; however its application is growing and course offerings at the undergraduate level are exploding. Biostatistics For Dummies is an excellent resource for those taking a course, as well as for those in need of a handy reference to this complex material. Biostatisticians—analysts of biological data—are charged with finding answers to some of the world's most pressing health questions: how safe or effective are drugs hitting the market today? What causes autism? What are the risk factors for cardiovascular disease? Are those risk factors different for men and women or different ethnic groups? Biostatistics For Dummies examines these and other questions associated with the study of biostatistics. Provides plain-English explanations of techniques and clinical examples to help Serves as an excellent course supplement for those struggling with the complexities of the biostatistics Tracks to a typical, introductory biostatistics course Biostatistics For Dummies is an excellent resource for anyone looking to succeed in this difficult course.
Biostatistics For Dummies
by John PezzulloScore your highest in biostatistics Biostatistics is a required course for students of medicine, epidemiology, forestry, agriculture, bioinformatics, and public health. In years past this course has been mainly a graduate-level requirement; however its application is growing and course offerings at the undergraduate level are exploding. Biostatistics For Dummies is an excellent resource for those taking a course, as well as for those in need of a handy reference to this complex material. Biostatisticians—analysts of biological data—are charged with finding answers to some of the world's most pressing health questions: how safe or effective are drugs hitting the market today? What causes autism? What are the risk factors for cardiovascular disease? Are those risk factors different for men and women or different ethnic groups? Biostatistics For Dummies examines these and other questions associated with the study of biostatistics. Provides plain-English explanations of techniques and clinical examples to help Serves as an excellent course supplement for those struggling with the complexities of the biostatistics Tracks to a typical, introductory biostatistics course Biostatistics For Dummies is an excellent resource for anyone looking to succeed in this difficult course.
Biostatistics For Dummies
by Monika Wahi John C. PezzulloBreak down biostatistics, make sense of complex concepts, and pass your class If you're taking biostatistics, you may need or want a little extra assistance as you make your way through. Biostatistics For Dummies follows a typical biostatistics course at the college level, helping you understand even the most difficult concepts, so you can get the grade you need. Start at the beginning by learning how to read and understand mathematical equations and conduct clinical research. Then, use your knowledge to analyze and graph your data. This new edition includes more example problems with step-by-step walkthroughs on how to use statistical software to analyze large datasets. Biostatistics For Dummies is your go-to guide for making sense of it all. Review basic statistics and decode mathematical equations Learn how to analyze and graph data from clinical research studies Look for relationships with correlation and regression Use software to properly analyze large datasets Anyone studying in clinical science, public health, pharmaceutical sciences, chemistry, and epidemiology-related fields will want this book to get through that biostatistics course.
Biostatistics For Dummies
by Monika Wahi John C. PezzulloBreak down biostatistics, make sense of complex concepts, and pass your class If you're taking biostatistics, you may need or want a little extra assistance as you make your way through. Biostatistics For Dummies follows a typical biostatistics course at the college level, helping you understand even the most difficult concepts, so you can get the grade you need. Start at the beginning by learning how to read and understand mathematical equations and conduct clinical research. Then, use your knowledge to analyze and graph your data. This new edition includes more example problems with step-by-step walkthroughs on how to use statistical software to analyze large datasets. Biostatistics For Dummies is your go-to guide for making sense of it all. Review basic statistics and decode mathematical equations Learn how to analyze and graph data from clinical research studies Look for relationships with correlation and regression Use software to properly analyze large datasets Anyone studying in clinical science, public health, pharmaceutical sciences, chemistry, and epidemiology-related fields will want this book to get through that biostatistics course.
Biostatistics for Epidemiologists
by Anders AhlbomBiostatistics for Epidemiologists is a unique book that provides a collection of methods that can be used to analyze data in most epidemiological studies. It examines the theoretical background of the methods described and discusses general principles that apply to the analysis of epidemiological data. Specific topics addressed include statistical interference in epidemiological research, important methods used for analyzing epidemiological data, multivariate models, dose-response analysis, analysis of the interaction between causes of disease, meta-analysis, and computer programs. Biostatistics for Epidemiologists will be a useful guide for all epidemiologists and public health professionals who rely on biostatistical data in their work.
Biostatistics for Epidemiologists
by Anders AhlbomBiostatistics for Epidemiologists is a unique book that provides a collection of methods that can be used to analyze data in most epidemiological studies. It examines the theoretical background of the methods described and discusses general principles that apply to the analysis of epidemiological data. Specific topics addressed include statistical interference in epidemiological research, important methods used for analyzing epidemiological data, multivariate models, dose-response analysis, analysis of the interaction between causes of disease, meta-analysis, and computer programs. Biostatistics for Epidemiologists will be a useful guide for all epidemiologists and public health professionals who rely on biostatistical data in their work.
Biostatistics for Human Genetic Epidemiology (Advances in Experimental Medicine and Biology #1082)
by Bertram K. ChanThe book illustrates how biostatistics may numerically summarize human genetic epidemiology using R, and may be used successfully to solve problems in quantitative Genetic Epidemiology Biostatistics for Human Genetic Epidemiology provides statistical methodologies and R recipes for human genetic epidemiologic problems. It begins by introducing all the necessary probabilistic and statistical foundations, before moving on to topics related human genetic epidemiology, with R codes illustrations for various examples. This clear and concise book covers human genetic epidemiology, using R in data analysis, including multivariate data analysis. It examines probabilistic and statistical theories for modeling human genetic epidemiology – leading the readers through an effective epidemiologic model, from simple to advanced levels. Classical mathematical, probabilistic, and statistical theory are thoroughly discussed and presented. This book also presents R as a calculator and using R in data analysis. Additionally, it covers Advanced Human Genetic Data Concepts, the Study of Human Genetic Variation, Manhattan Plots, as well as the Procedures for Multiple Comparison. Numerous Worked Examples are provided for illustrations of concepts and real-life applications. Biostatistics for Human Genetic Epidemiology is an ideal reference for professionals and students in Medicine (particularly in Preventive Medicine and Public Health Medical Practices), as well as in Genetics, Epidemiology, and Biostatistics.
Biostatistics for Oral Healthcare
by Jay S. Kim Ronald J. DaileyBiostatistics for Oral Healthcare offers students, practitioners and instructors alike a comprehensive guide to mastering biostatistics and their application to oral healthcare. Drawing on situations and methods from dentistry and oral healthcare, this book provides a thorough treatment of statistical concepts in order to promote in-depth and correct comprehension, supported throughout by technical discussion and a multitude of practical examples.
Biostatistics for Radiologists: Planning, Performing, and Writing a Radiologic Study
by Francesco Sardanelli Giovanni Di LeoThe aim of this book is to present statistical problems and methods in a friendly way to radiologists, emphasizing statistical issues and methods most frequently used in radiological studies (e.g., nonparametric tests, analysis of intra- and interobserver reproducibility, comparison of sensitivity and specificity among different imaging modality, difference between clinical and screening application of diagnostic tests, ect.). The tests will be presented starting from a radiological "problem" and all examples of statistical methods applications will be "radiological".
Biostatistics for the Biological and Health Sciences with Statdisk: Pearson New International Edition
by Marc M. Triola Mario F. TriolaBiostatistics for the Biological and Health Sciences is the result of collaboration between the author of the #1 statistics book in the country and an expert in the biological sciences field. The major objective of this book is to provide the best possible introduction to statistics for students and professors in the biological, life, and health sciences. This goal is realized through a friendly writing style, content that reflects the important features of a modern introductory statistics course, an abundance of real data and biological applications, and a variety of pedagogical components to help students succeed in their study of biological statistics.
Biostatistics in Public Health Using STATA
by Erick L. Suárez Cynthia M. Pérez Graciela M. Nogueras Camille Moreno-GorrínStriking a balance between theory, application, and programming, Biostatistics in Public Health Using STATA is a user-friendly guide to applied statistical analysis in public health using STATA version 14. The book supplies public health practitioners and students with the opportunity to gain expertise in the application of statistics in epidemiolo
The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness
by Gilberto Levy Bruce LevinA practical and clarifying approach to aging and aging-related diseases Providing a thorough and extensive theoretical framework, The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness addresses the surprisingly subtlenotion—with consequential biomedical and public health relevance—of what it means for acondition to be related to aging. In this pursuit, the book presents a new quantitative methodto examine the relative contributions of genetic and environmental factors to mortality anddisease incidence in a population. With input from evolutionary biology, population genetics, demography, and epidemiology, this medically motivated book describes an index of aging-relatedness and also features: Original results on the asymptotic behavior of the minimum of time-to-event random variables, which extends those of the classical statistical theory of extreme values A comprehensive and satisfactory explanation based on biological principles of the Gompertz pattern of mortality in human populations The development of an evolution-based model of causation relevant to mortality and aging-related diseases of complex etiology An explanation of how and why the description of human mortality by the Gompertz distribution can be improved upon from first principles The amply illustrated analysis of real-world data, including a program for conducting the analysis written in the freely available R statistical software Technical appendices including mathematical material as well as an extensive and multidisciplinary bibliography on aging and aging-related diseases The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness is an excellent resource for practitioners and researchers with an interest in aging and aging-related diseases from the fields of medicine, biology, gerontology, biostatistics, epidemiology, demography, and public health.
The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness
by Gilberto Levy Bruce LevinA practical and clarifying approach to aging and aging-related diseases Providing a thorough and extensive theoretical framework, The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness addresses the surprisingly subtlenotion—with consequential biomedical and public health relevance—of what it means for acondition to be related to aging. In this pursuit, the book presents a new quantitative methodto examine the relative contributions of genetic and environmental factors to mortality anddisease incidence in a population. With input from evolutionary biology, population genetics, demography, and epidemiology, this medically motivated book describes an index of aging-relatedness and also features: Original results on the asymptotic behavior of the minimum of time-to-event random variables, which extends those of the classical statistical theory of extreme values A comprehensive and satisfactory explanation based on biological principles of the Gompertz pattern of mortality in human populations The development of an evolution-based model of causation relevant to mortality and aging-related diseases of complex etiology An explanation of how and why the description of human mortality by the Gompertz distribution can be improved upon from first principles The amply illustrated analysis of real-world data, including a program for conducting the analysis written in the freely available R statistical software Technical appendices including mathematical material as well as an extensive and multidisciplinary bibliography on aging and aging-related diseases The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness is an excellent resource for practitioners and researchers with an interest in aging and aging-related diseases from the fields of medicine, biology, gerontology, biostatistics, epidemiology, demography, and public health.
Biostatistics with R: An Introduction to Statistics Through Biological Data (Use R!)
by Babak ShahbabaBiostatistics with R is designed around the dynamic interplay among statistical methods, their applications in biology, and their implementation. The book explains basic statistical concepts with a simple yet rigorous language. The development of ideas is in the context of real applied problems, for which step-by-step instructions for using R and R-Commander are provided. Topics include data exploration, estimation, hypothesis testing, linear regression analysis, and clustering with two appendices on installing and using R and R-Commander. A novel feature of this book is an introduction to Bayesian analysis.This author discusses basic statistical analysis through a series of biological examples using R and R-Commander as computational tools. The book is ideal for instructors of basic statistics for biologists and other health scientists. The step-by-step application of statistical methods discussed in this book allows readers, who are interested in statistics and its application in biology, to use the book as a self-learning text.
Biostatistics With 'R': A Guide for Medical Doctors
by Marco MoscarelliThis book aims not only to introduce fundamental biostatistics topics but to explain them through R-project (R-studio). 'R' is perhaps the more used statistical software in the medical field. It is structured as a 'scientific journey' and comes with a sham yet realistic dataset ready to be analysed. The dataset along with the R-script can be downloaded from GitHub, and each chapter has dedicated scripts that will enhance the understanding of R and biostatistics. Specifically designed for whoever works in the medical-academic environment, this practical guide will help the reader to become familiar with basic to advanced biostatistics topic (descriptive - analysis / regression etc.) and to gain solid knowledge of R.