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Bioökonomie und regionaler Strukturwandel: Wertschöpfung, Innovation und Nachhaltigkeit planen und umsetzen (SDG - Forschung, Konzepte, Lösungsansätze zur Nachhaltigkeit)
by Angela-Verena Hassel Daniel Schiller Stefan Seiberling Christian Theel Steffen FleßaBioökonomie ist eine neue branchenübergreifende Form des Wirtschaftens, die das Potenzial hat, die bisherige Ökonomie und einzelne Regionen grundlegend zu verändern. Dieser Überzeugung folgend stellen die Herausgeber und Autoren dieses Buches den aktuellen Wissenstand aus Theorie und Praxis der Bioökonomie zusammen, entwickeln neue Methoden für einen bioökonomischen Strukturwandel und reflektieren bestehende Bioökonomiekonzepte. Der komplexe und vielschichtige Prozess einer pflanzenbasierten Bioökonomie in ländlichen Räumen wird aus unterschiedlichen Perspektiven betrachtet. Zunächst werden ökonomische Grundlagen sowohl aus gesamt- als auch aus einzelwirtschaftlicher Sicht diskutiert. Dem schließen sich Beispiele an, wie regionale Innovationsnetzwerke und Wertschöpfungsketten der Bioökonomie einen Beitrag zur nachhaltigen Regionalentwicklung und zum gesellschaftlichen Wandel leisten können. Die darauf aufbauende Analyse legt dar, wie verschiedene Akteure und Prozesse eine regionale Bioökonomie in der Praxis etablieren können. Ausgewählte Anwendungs- und Umsetzungsbeispiele für Innovationen pflanzenbasierter Bioökonomie im nordöstlichen Mecklenburg-Vorpommern runden das Buch ab und zeigen das Potenzial für eine Transformation der Wirtschaft in der Region und darüber hinaus.
Bioorganic and Enzymatic Catalysis
by Wolf-D. WoggonBioorganic and Enzymatic Catalysis Direct comparison of enzymatic reactions and corresponding catalytic transformations in the laboratory Bioorganic and Enzymatic Catalysis covers the most important enzymatic reactions and related catalytic bioorganic reactions using a new approach: Each enzymatic reaction type is compared with organocatalytic, organometallic and other alternative reactions, allowing the reader to understand catalytic reactions in a much-integrated way. For example, in a chapter that describes aldolases corresponding reactions using catalytic antibodies, organocatalytic reagents and metal complexes are discussed. Written by a well-known expert in the field with more than 30 years of experience in organic and bioorganic chemistry, Bioorganic and Enzymatic Catalysis covers sample topics such as: Enzymatic C-C bond formation using aldolases Claisen-type C-C bond formation involving fatty acid synthases and polyketide synthases Biomimetic cyclisations involving carbenium ions Enzymatic oxidation and C-H activation Dioxygenases and oxidoreductases With its unique approach, Bioorganic and Enzymatic Catalysis is a valuable source of information for professionals and researchers in academia and industry as well as graduate and PhD students working in the fields of organic chemistry, biochemistry, and life sciences.
Bioorganic and Enzymatic Catalysis
by Wolf-D. WoggonBioorganic and Enzymatic Catalysis Direct comparison of enzymatic reactions and corresponding catalytic transformations in the laboratory Bioorganic and Enzymatic Catalysis covers the most important enzymatic reactions and related catalytic bioorganic reactions using a new approach: Each enzymatic reaction type is compared with organocatalytic, organometallic and other alternative reactions, allowing the reader to understand catalytic reactions in a much-integrated way. For example, in a chapter that describes aldolases corresponding reactions using catalytic antibodies, organocatalytic reagents and metal complexes are discussed. Written by a well-known expert in the field with more than 30 years of experience in organic and bioorganic chemistry, Bioorganic and Enzymatic Catalysis covers sample topics such as: Enzymatic C-C bond formation using aldolases Claisen-type C-C bond formation involving fatty acid synthases and polyketide synthases Biomimetic cyclisations involving carbenium ions Enzymatic oxidation and C-H activation Dioxygenases and oxidoreductases With its unique approach, Bioorganic and Enzymatic Catalysis is a valuable source of information for professionals and researchers in academia and industry as well as graduate and PhD students working in the fields of organic chemistry, biochemistry, and life sciences.
Bioorganic and Medicinal Chemistry of Fluorine
by Jean-Pierre Bégué Daniele Bonnet-DelponProvides a thorough overview of the role of fluorine in pharmaceutical science and development Includes chapters on fluorinated analogues of natural products, fluorinated amino acids and peptides, and derivatives of sugars Classifies marketed and in-development fluorinated pharmaceuticals according to their therapeutic classes
Bioorganic Chemistry: A Chemical Approach to Enzyme Action (Springer Advanced Texts in Chemistry)
by H. Dugas C. PenneySpringer Advanced Texts in Chemistry New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical ther modynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases the availability of texts in active research areas should help stimulate the creation of new courses. New York, New York CHARLES R.
Bioorganic Chemistry: A Chemical Approach to Enzyme Action (Springer Advanced Texts in Chemistry)
by Hermann DugasThis widely-praised textbook is particularly suited for advanced undergraduates or graduates in chemistry, biochemistry, medicinal chemistry, and pharmacology. The third edition has been substantially revised to reflect new research in the field, and features a major new chapter on self-assembly, auto-organization, and molecular devices. The outstanding figures remain a highlight of the book, and were described in an earlier edition as "the best I've seen for showing the organic chemistry of biomolecules." (Quart. Rev. Biol.)
Bioorganic Chemistry: A Chemical Approach to Enzyme Action (Springer Advanced Texts in Chemistry)
by Hermann DugasSpringer Advanced Texts In Chemistry New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical thermody namics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research that is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases the availability of texts in active research areas should help stimulate the creation of new courses.
Bioorganic Chemistry Frontiers (Bioorganic Chemistry Frontiers #3)
by E. V. Anslyn A. Bacher W. Eisenreich C. L. Hannon M. W. Hosseini K. Kano G. V. Kiedrowski K. Kis R. Ladenstein A. Plückthun G. Richter J. Scheuring S. WeinkaufBioorganic Chemistry Frontiers (Bioorganic Chemistry Frontiers #2)
by M. Banaszczyk J. Chin D. R. Corey C. Dietrich-Buchecker A. D. Hamilton V. Jubian J. Kikuchi J. H. Kim K. Mrejen Y. Murakami J. P. Sauvage P. G. Schultz S. C. Zimmerman R. N. ZuckermannProgress in biological and biochemical research is based mainly on a better understanding of life processes on a molecular level. Modern chemical techniques for structural elucidation even of sophisticated biomolecules and theoretical and mechanistic considerations help us to understand structure-function relations, metabolic processes, molecular and cellular recognition, and the reproduction of life. This series, Bioorganic Chemistry Frontiers, will bring together critical reviews on the progress in this field.
Bioorganic Chemistry Frontiers (Bioorganic Chemistry Frontiers #1)
by S. A. Benner F. Ebmeyer L. Echegoyen A. D. Ellington T. M. Fyles G. W. Gokel S. Shinkai F. VögtleBetter understanding of life processes on a molecular level is the aim of Bioorganic Chemistry. Structure elucidation, synthesis of biomimetic models, theoretical and mechanistic concepts e.g. of enzyme action are the basic tools. The new series will bring together critical reviews on the progress in this field.
Bioorganic Chemistry in Healthcare and Technology (Nato Science Series A: #207)
by Upendra K. Pandit Frank C. AlderweireldtIn current thinking, Bioorganic Chemistry may be defined as the area of chemistry which lies in the border region between organic chemistry and biology and which describes and analyzes biological phenomena in terms of detailed molecular structures and molecular mechanisms. This molecular-level view of biological processes is not only essential to their fuller understanding but also serves as the platform for the application of the principles of such processes to areas of health care and technology. The objective of the ASI workshop on " Bioorganic Chemistry in Healthcare and Technology", held in the Hengelhoef Congress Centre in Houthalen-Helchteren, Belgium, from September 18-21, 1990, was to bring together most of the international experts in the field to discuss the current developments and new trends in bioorganic chemistry, especially in relation to the selected theme. The book presents nineteen invited plenary and session lectures and eighteen posters. These cover areas of (i) molecular design of therapeutic and agronomical agents based npon mechanistic rationale or drug-receptor interactions, (ii) production of substances of commercial value via combined organic chemical and bio-chemical methodologies, (iii) fundamental studies on the molecular mechanisms of enzymes and (iv) the evolution of conceptually new molecular systems which are programmed to execute specific recognition and/or catalytic functions. An abstracted version of the plenary discussion held at the end of the workshop is also included. We feel confident that the subject matter of this book will be of interest to a broad group of chemists engaged in academic or industrial research.
Bioorganic Chemistry of Biological Signal Transduction (Topics in Current Chemistry #211)
by G. Dorman P. J. Hergenrother C. Herrmann J. Kuhlmann A. Levitzki S. F. Martin G. Müller M. Thutewohl H. WaldmannBioorganic Marine Chemistry (Bioorganic Marine Chemistry #1)
by John W. Blunt William Fenical Nobuhiro Fusetani Peter Karuso Richard T. Luibrand Murray H.G. Munro Valerie J. PaulThe present series, "Bio-organic Marine Chemistry," is being launched at a time when we have the fundamental knowledge and the requisite instrumentation to probe the molecular basis of many biological phenomena. The final volume of "Marine Natural Products-Chemical and Biological Perspectives" (Academic Press), which may be con sidered the precursor of this series, was published in 1983. In that series, which I edited, primary emphasis was placed on molecular structure and phyletic relationships. This focus was compatible with the major concerns of a growing research community in the field of marine natural products. Moreover, a need existed for timely reviews of a rapidly expanding and widely scattered primary literature. As I read again the Preface to Volume 1 (1978), I am amazed at the changes in direction and emphasis which have taken place during these few intervening years. Sufficient basic data are now at hand to gauge the breadth of the marine natural product spectrum and to raise questions of functions, both within and outside the marine ecosystem. Although we have few answers, the questions have become meaningful and pointed. Furthermore, the task of tracking and cataloguing the steady stream of fascinating new structures has been assumed by Faulkner's periodic surveys in Natural Product Reports, a bimonthly publication of the Royal Society of Chemistry. The study of marine natural products remains firmly anchored in chemistry, i. e. in molecular integrity, yet continues to seek greater involvement in functional biology.
Bioorganic Marine Chemistry (Bioorganic Marine Chemistry #2)
by J. C. Coll G. B. Elyakov R. J. Quinn P. W. Sammarco V. A. Stonik K. TachibanaBurgeoning research into marine natural products during the past two decades has in no small measure been due to an heightened and world-wide interest in the ocean, to the development of new sophisticated computer-driven instrumentation, and to major advances in separation science. Organic chemists have been fully aware that processes in living systems occur in an aqueous medium. Nevertheless, the chemists who have specialized in the study of small molecules have found it expedient to use organic rather than aqueous solvents for the isolation and manipulation of secondary metabolites. The emergence of new chromatographic techniques, the promise of rewarding results, not to mention the relevance of polar molecules to life itself, have contributed to a new awareness of the importance of organic chemistry in an aqueous medium. The first chapter in Volume 2 of Bioorganic Marine Chemistry reflects the growing interest and concern with water-soluble com pounds. Quinn, who pioneered the separation of such molecules, has contributed a review which closely links techniques with results and is based on practical experience. The second chapter, by Stonik and Elyakov, examines the vast chemical literature of the phylum Echinodermata - over one fourth of it in difficulty accessible Russian language publications. The Soviet authors evaluate the data for their suitability as chemotaxonomic markers.
Bioorganic Marine Chemistry (Bioorganic Marine Chemistry #3)
by A. R. Davis M. P. Foster C. M. Ireland J. Kobayashi M. Kobayashi O. J. McConnell T. C. McKee T. F. Molinski D. J. Newman Y. Ohizumi D. M. Roll K. Sakata K. Snader M. Suffness N. Suzuki J. C. Swersey N. M. Targett C. M. Young T. M. ZabriskieThe first three chapters of Vol. 3 of Bio-organic Marine Chemistry deal with the chemistry and function of peptides. Chapter 1 by Ireland and coworkers serves as an introduction to marine-derived peptides. It is arranged phyletically and encompasses the entire range from dipeptides to a compound with 95 amino acid residues. Peptides involved in primary metabolism and hence belonging to the realm of macromolecular biochemistry are excluded. However, it might be mentioned in passing that the dividing line between large and small molecule chemistry is continually becoming less distinct. Not only are more compounds of intermediate size, from 1,000 to 10,000 dalton, being discovered, but instruments and techniques, particularly in mass spectrometry and nuclear magnetic resonance have been developed for their structural elucidation by what is considered small molecule methodology. Two groups of peptides are discussed in separate chapters. Biologists who have observed and described the mating behavior of diverse species of marine invertebrates have long surmised that a chemical mechanism might be operating in many cases of individual as well as mass fertilization. The chemical activators of sea urchin sperm prove to be a series of peptides, whose structures and activity are discussed by Suzuki.
Bioorganic Marine Chemistry (Bioorganic Marine Chemistry #4)
by T. Higa L. M. Rzepecki N. M. Targett D. Uemura J. H. Waite J. E. WardBioorganic Phase in Natural Food: An Overview
by S. Mohana Roopan G. MadhumithaThe focus of this singular work is to discuss the role and importance of bioorganic phase in food products-providing the first major reference source for researchers looking to understand all aspects of the isolation, extraction and application of this major element in natural foods. From the identifying features to its applications through biotechnology and nanobiotechnology, this book covers all of the important aspects of bioorganic phase and points to future uses and methods. With chapters focusing on phase extraction and application, food product synthesis and nanoparticle application, Bioorganic Phase in Natural Food: An Overview covers both conventional and non-conventional approaches for the extraction of bioorganic phase from various food sources. Toxicity studies in nanoparticles are presented, and the vital role played by bioorganic phase toward nanoparticles synthesis is outlined in full. For any researcher looking for complete coverage of all main aspects of bioorganic phase in foods, this work provides a comprehensive and well-researched view of this important subject. .
Bioorganic Synthesis: An Introduction
by Gary W. MorrowBuilding on the foundation of a one-year introductory course in organic chemistry, Bioorganic Synthesis: An Introduction focuses on organic reactions involved in the biosynthesis of naturally-occurring organic compounds with special emphasis on natural products of pharmacological interest. The book is designed specifically for undergraduate students, rather than as an exhaustive reference work for graduate students or professional researchers and is intended to support undergraduate courses for students majoring in chemistry, biochemistry, biology, pre-medicine, and bioengineering programs who would benefit from a deeper understanding of the chemical logic of reactions carried out in organisms and the origins and uses of the important organic compounds they often produce. The book assumes no prior background in biochemistry and consists of eight chapters: i) a brief review of relevant topics from introductory organic chemistry; ii) presentation of essential organic and biochemical reactions used throughout the book along with a brief introduction to coenzymes; iii) review of basic carbohydrates and the biosynthesis of amino acids; iv) the terpenoid pathway for biosynthesis of all important classes of terpenoids and steroids; v) the acetate pathway for biosynthesis of saturated and unsaturated fatty acids, prostaglandins and acetate-derived polyketide natural products; vi) the biosynthesis of the shikimate pathway products derived from aromatic amino acids; vii) an introduction to biosynthesis of major alkaloids and related nitrogenous compounds; and viii) an overview of laboratory organic synthesis as it relates to the challenges faced by synthetic and medicinal chemists who must recreate intricate natural product structures in the laboratory.
Bioorganic Synthesis: An Introduction
by Gary W. MorrowBuilding on the foundation of a one-year introductory course in organic chemistry, Bioorganic Synthesis: An Introduction focuses on organic reactions involved in the biosynthesis of naturally-occurring organic compounds with special emphasis on natural products of pharmacological interest. The book is designed specifically for undergraduate students, rather than as an exhaustive reference work for graduate students or professional researchers and is intended to support undergraduate courses for students majoring in chemistry, biochemistry, biology, pre-medicine, and bioengineering programs who would benefit from a deeper understanding of the chemical logic of reactions carried out in organisms and the origins and uses of the important organic compounds they often produce. The book assumes no prior background in biochemistry and consists of eight chapters: i) a brief review of relevant topics from introductory organic chemistry; ii) presentation of essential organic and biochemical reactions used throughout the book along with a brief introduction to coenzymes; iii) review of basic carbohydrates and the biosynthesis of amino acids; iv) the terpenoid pathway for biosynthesis of all important classes of terpenoids and steroids; v) the acetate pathway for biosynthesis of saturated and unsaturated fatty acids, prostaglandins and acetate-derived polyketide natural products; vi) the biosynthesis of the shikimate pathway products derived from aromatic amino acids; vii) an introduction to biosynthesis of major alkaloids and related nitrogenous compounds; and viii) an overview of laboratory organic synthesis as it relates to the challenges faced by synthetic and medicinal chemists who must recreate intricate natural product structures in the laboratory.
Bioorganometallic Chemistry: Applications in Drug Discovery, Biocatalysis, and Imaging
by Gérard Jaouen Michèle SalmainAn up-to-date reference reflecting the significant advances and important breakthroughs made in this emerging discipline over the last decade. As such, the book provides an overview of the latest developments and future trends in the field, focusing on such applications as the development of potentially active organometallic drugs against incurable diseases, as well as in such areas as catalysis, energy, analytical chemistry, and imaging. The renowned editor, who established the term "bioorganometallics", and his international team of experts have put together a valuable resource for researchers in organometallic, inorganic, medicinal, and biochemistry.
Bioorganometallic Chemistry: Applications in Drug Discovery, Biocatalysis, and Imaging
by Gerard Jaouen Michèle SalmainAn up-to-date reference reflecting the significant advances and important breakthroughs made in this emerging discipline over the last decade. As such, the book provides an overview of the latest developments and future trends in the field, focusing on such applications as the development of potentially active organometallic drugs against incurable diseases, as well as in such areas as catalysis, energy, analytical chemistry, and imaging. The renowned editor, who established the term "bioorganometallics", and his international team of experts have put together a valuable resource for researchers in organometallic, inorganic, medicinal, and biochemistry.
Bioorganometallics: Biomolecules, Labeling, Medicine
by Gérard JaouenThis first comprehensive book to cover the expanding field of bioorganometallics represents the perfect starting point for beginners but also an excellent source of high quality information for experts in the field. Edited by a pioneer in the field with an excellent standing within the community, this book begins with the history of bioorganometallics, before going on to cover pharmaceuticals, bioorganometallic chemistry and radiopharmaceuticals. A must for bioinorganic chemists, the pharmaceutical industry, chemists working in organometallics and biochemists.
Biopacemaking (Series in Biomedical Engineering)
by J. A. E Spaan Ruben Coronel Jacques M. T. De Bakker Antonio ZazaThe development of a bio-engineered pacemaker is of substantial clinical and also scientific interest because it promises to overcome several limitations of electronic pacemakers. Moreover it may answer the longstanding question of whether the complex structure of the sinus node is indeed a prerequisite for reliable pacemaking, or simpler structures might work as well. This book gives an overview of the current state-of-the-art of creating a bio-engineered pacemaker. It shows the approaches to develop of genetic and cell-based engineering methods suitable to implement them with safety and stability. It also illuminates the problems that need to be solved before bio-pacemaking can be considered for clinical use.
Biopackaging
by Martin A. MasuelliThis book examines the whole range of modern packaging options. It covers edible packaging based on carbohydrates, proteins, antioxidative and antimicrobial packaging, and the chemistry of food and food packaging, such as plasticization and polymer morphology. Issues related to shelf life and biodegradability are also discussed, in addition to newly discovered processing and preservation techniques, most notably modified atmosphere packaging (MAP) and active packaging (AP).