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Candace Pert: Genius, Greed, and Madness in the World of Science

by Pamela Ryckman

"...a truly insightful narrative on what it can mean to be a woman at the cutting edge of science." —THE WALL STREET JOURNALThe story of maverick scientist Candace Pert, whose groundbreaking research and book Molecules of Emotion introduced the world to the mind-body connection, opioid receptors, and peptide T, and her fight for recognition in a toxic healthcare system. Candace Pert stood at the dawn of three revolutions: the women&’s movement, integrative health, and psychopharmacology. A scientific prodigy, she was 30 years ahead of her time, preaching a holistic, interdisciplinary approach to healthcare and medicine long before yoga hit the mainstream and &“wellness&” took root in our vernacular. Her bestselling book Molecules of Emotion made her the mother of the Mind/Body Revolution, launching a paradigm shift in medicine. Deepak Chopra credits her with creating his career, and he said as much in his eulogy at her funeral. Candace began her career as an unbridled maverick. In 1972, as a 26-year-old graduate student at Johns Hopkins, she discovered the opiate receptor, revolutionizing her field and enabling pharmacologists to design new classifications of drugs from Prozac to Viagra to Percocet and OxyContin. The tragic irony of her breakthrough, touted as the first step to end heroin addiction, is that it helped spawn a virulent epidemic of drug dependence. Facing the largest public health crisis of the 21st century, Candace was incensed that the Hippocratic oath—&“first, do no harm&”—would succumb to greed, and as witness to this abuse of power, she was one of few scientists courageous enough to protest. Later, as Chief of Brain Biochemistry at the National Institutes of Health, Candace created Peptide T, the non-toxic treatment for HIV featured in Dallas BuyersClub. As the AIDS pandemic raged, triggering panic across Reagan-era America, the U.S. government poured massive amounts of money into finding a cure, sparking a battle among scientists for funding and power. Bested by rivals with competing drugs yet desperate to help, Candace went rogue, becoming a lynchpin in the black market for Peptide T. After a scandalous departure from her tenured position at the NIH, Candace launched a series of private companies with Michael Ruff, her second husband and collaborator. Naïve to the world of business, she was manipulated by investors keen to wrest control of her discoveries. But Candace too became tainted, believing that her noble ends would justify devious means. Like a mythic hero, she succumbed to a fatal flaw, and her greatest strengths—singularity of purpose and blind faith in her own virtuosity—would prove to be her undoing.

Candid Creatures: How Camera Traps Reveal the Mysteries of Nature

by Roland Kays

In Candid Creatures, the first major book to reveal the secret lives of animals through motion-sensitive game cameras, biologist Roland Kays has assembled over 600 remarkable photographs. Drawing from archives of millions of color and night-vision photographs collected by hundreds of researchers, Kays has selected images that show the unique perspectives of wildlife from throughout the world. Using these photos, he tells the stories of scientific discoveries that camera traps have enabled, such as living proof of species thought to have been extinct and details of predator-prey interactions.Each image captures a moment frozen in the camera;€™s flash as animals move through their wild habitats. Kays also discusses how scientists use camera traps to address conservation issues, creating solutions that allow humans and wild animals to coexist. More than just a collection of amazing animal pictures, the book;€™s text, maps, and illustrations work together to describe the latest findings in the fast-moving field of wildlife research. Candid Creatures is a testament to how the explosion of game cameras around the world has revolutionized the study of animal ecology. The powerful combination of pictures and stories of discovery will fascinate anyone interested in science, nature, wildlife biology, or photography.

Candid Creatures: How Camera Traps Reveal the Mysteries of Nature

by Roland Kays

In Candid Creatures, the first major book to reveal the secret lives of animals through motion-sensitive game cameras, biologist Roland Kays has assembled over 600 remarkable photographs. Drawing from archives of millions of color and night-vision photographs collected by hundreds of researchers, Kays has selected images that show the unique perspectives of wildlife from throughout the world. Using these photos, he tells the stories of scientific discoveries that camera traps have enabled, such as living proof of species thought to have been extinct and details of predator-prey interactions.Each image captures a moment frozen in the camera;€™s flash as animals move through their wild habitats. Kays also discusses how scientists use camera traps to address conservation issues, creating solutions that allow humans and wild animals to coexist. More than just a collection of amazing animal pictures, the book;€™s text, maps, and illustrations work together to describe the latest findings in the fast-moving field of wildlife research. Candid Creatures is a testament to how the explosion of game cameras around the world has revolutionized the study of animal ecology. The powerful combination of pictures and stories of discovery will fascinate anyone interested in science, nature, wildlife biology, or photography.

Candida Albicans: Cellular and Molecular Biology

by Rajendra Prasad

Candida, which was discovered more than a century ago as a causative organism of oral thrush, is now thought to potentially infect almost every tissue of the human body. Although we still do not have a safe anti-candida drug, the growing pace of progess of research on Candida albicans holds promise that a breakthrough is imminent. Though many monographs and articles on candida and candidoses have appeared in recent years, they mostly cover the clinical aspects. This particular text, however, explains the more basic features of candida including the molecular genetics, molecular biology and immunology of the cell wall, the molecular basis of morphogenesis and the structure and function of the plasma membrane. The role of anti-candida drugs and their mechanism of action are also discussed.

Candida albicans: Cellular And Molecular Biology

by Rajendra Prasad

This book on Candida albicans and similar pathogens provides a timely overview of the groundbreaking discoveries made in the areas of drug resistance, host–pathogen interactions, virulence, host immune system modulation, etc., in the last two decades. This comprehensive 2nd Edition includes chapters on fungal infections, hyphal morphogenesis, molecular mechanisms of antifungal resistance, antifungal agents, multidrug transporters, virulence mechanisms in Candida albicans, host–pathogen interactions, the cell wall, fungal biofilms, lipids and antifungal resistance, signaling mechanisms and last but not the least host-immune responses. As such, it offers an ideal reference guide for mycologists, researchers, pharmacists, clinicians, and undergraduate students engaged or interested in fungal research. It will also benefit clinicians, who are required to keep abreast of the current state of research on antifungal drug resistance and antifungal development.

Candida Albicans: Methods and Protocols (Methods in Molecular Biology #499)

by Ronald L. Cihlar and Richard A. Calderone

Over the course of the past decade, there have been remarkable advances in the study of human pathogenic fungi. These developments have taken place throughout a wide range of disciplines, and have come as the result of newly available genome sequences of pathogens such as candida albicans and other model fungi. In Candida Albicans: Methods and Protocols, expert researchers explore these exciting new insights, focusing on the study of medically important fungi and Candida spp in particular. Chapters examine critical aspects of molecular methods, providing information on reporter gene assays, transformation, gene expression in vivo, and methods for large-scale gene disruption. At the same time, the work includes in-depth descriptions of disease models of candidiasis, facts about strain identification, and guidelines on the preparation of samples for proteomic investigations and tandem affinity purification. Composed in the highly successful "Methods in Molecular Biology™" series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting edge, Candida Albicans: Methods and Protocols is an invaluable source of methods for investigators in the exhilarating fields of medical and molecular mycology.

Candida and Candidamycosis (F.E.M.S. Symposium Series #50)

by Emel Tümbay Heinz P. R. Seeliger Özdem Ang

Scientists from 24 countries who participated in the ~ Symposium on Candida and Candidamycosis, 24-28 April 1989, Antalya, Turkey, have made important contributions to a better understanding of Candida and its infections - by their presence, presentations and discussions in the meeting. The Turkish Microbiological Society, organizing the Symposium in the name of the Federation of European Microbiological Societies (FEMS), thanks all participants for realising this important meeting on such an important subject. In this book the full manuscripts of invited and free papers of the meeting are presented. The Editors extend their sincere thanks to all contributors of papers; to FEMS for encouraging and undertaking the arrangements for publication; to Ege University Publishing House for printing; to Plenum Publishing Company for publishing; and to all colleagues and friends who with their help contributed to this book. The Editors wish that this volume would contribute to a better understanding of Candida and its infections by colleagues working and/or interested in mycology and mycotic diseases.

Candida auris: Methods and Protocols (Methods in Molecular Biology #2517)

by Alexander Lorenz

This volume covers the latest experimental protocols used by researchers to study the recently emerged fungal pathogen of humans, Candida auris, and also explores the pathogen’s antifungal resistance, virulence, and pathogenicity. The chapters in this book cover topics such as the identification of C. auris in clinic samples by PCR and mass spectrometry; molecular typing to identify clade affiliation; genetic manipulation; genome analysis by bioinformatics; and phenotypic characterization using various biochemical, mass spectrometry, microscopy, and flow cytometry approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and practical, Candida auris: Methods and Protocols is a valuable resource for researchers interested in learning more about this developing field.

Candida Species: Methods and Protocols (Methods in Molecular Biology #2542)

by Richard Calderone

This updated volume explores Candida and candidiasis methods, useful to a wide variety of Candida scientists including those new to the field. Beginning with a section on the Candida genome, the book continues by covering techniques for antifungal discovery and studying resistance, pathogenesis and virulence, communities, as well as immunity. Biofilm protocols are also featured. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Candida Species: Methods and Protocols, Second Edition serves as an ideal guide for researchers working to further our understanding of this family of infective fungi.

Candida Species: Methods and Protocols (Methods in Molecular Biology #1356)

by Richard Calderone and Ronald Cihlar

This volume provides detailed discussion of a variety of important techniques that researchers use to study fungal molecular biology and pathogenesis. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Candida Species: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Candy Bites: The Science of Sweets

by Richard W. Hartel AnnaKate Hartel

This delicious new book reveals the fascinating science behind some of our favorite candies. If you’ve ever wondered how candy corn is made or whether Baby Ruth bars really float, as in the movie Caddy shack, then this engaging collection of food for thought is guaranteed to satisfy your hunger for knowledge. As well as delving into candy facts and myths such as the so-called ‘sugar high’ and the long history of making sweetmeats, the authors explore the chemistry of a candy store full of famous treats, from Tootsie Rolls to Pixy Styx and from Jawbreakers to Jordan Almonds. They reveal what makes bubble gum bubbly and why a Charleston Chew is so chewy.Written in an engaging, accessible and humorous style that makes you laugh as you learn, Candy Bites doesn’t shy away from the hard facts or the hard questions, about candy. It tackles the chemistry of hydrocolloids in gummy bears alongside the relationship between candy and obesity and between candy and dental cavities. The chapters open a window on the commercial and industrial chemistry of candy manufacture, making this book a regular Pez dispenser of little-known, yet captivating factoids.

Canguilhem (Key Contemporary Thinkers)

by Stuart Elden

Georges Canguilhem (1904–95) was an influential historian and philosopher of science, as renowned for his teaching as for his writings. He is best known for his book The Normal and the Pathological, originally his doctoral thesis in medicine, but he also wrote a thesis in philosophy on the concept of the reflex, supervised by Gaston Bachelard. He was the sponsor of Michel Foucault’s doctoral thesis on madness. However, his work extends far beyond what is suggested by his association with these thinkers. Canguilhem also produced a series of important works on the natural sciences, including studies of evolution, psychology, vitalism and mechanism, experimentation, monstrosity and disease. Stuart Elden discusses the whole of this important thinker’s complex work, including recently rediscovered texts and archival materials. Canguilhem always approached questions historically, examining how it was that we came to a significant moment in time, outlining tensions, detours and paths not taken. The first comprehensive study in English, this book is a crucial guide for those coming to terms with Canguilhem’s important contributions, and will appeal to researchers and students from a range of fields.

Canguilhem (Key Contemporary Thinkers)

by Stuart Elden

Georges Canguilhem (1904–95) was an influential historian and philosopher of science, as renowned for his teaching as for his writings. He is best known for his book The Normal and the Pathological, originally his doctoral thesis in medicine, but he also wrote a thesis in philosophy on the concept of the reflex, supervised by Gaston Bachelard. He was the sponsor of Michel Foucault’s doctoral thesis on madness. However, his work extends far beyond what is suggested by his association with these thinkers. Canguilhem also produced a series of important works on the natural sciences, including studies of evolution, psychology, vitalism and mechanism, experimentation, monstrosity and disease. Stuart Elden discusses the whole of this important thinker’s complex work, including recently rediscovered texts and archival materials. Canguilhem always approached questions historically, examining how it was that we came to a significant moment in time, outlining tensions, detours and paths not taken. The first comprehensive study in English, this book is a crucial guide for those coming to terms with Canguilhem’s important contributions, and will appeal to researchers and students from a range of fields.

Canine and Feline Dementia: Molecular Basis, Diagnostics and Therapy

by Gary Landsberg Aladár Maďari Norbert Žilka

The book deeply focuses on the epidemiology, diagnostics, therapy and molecular basis of canine and feline dementia or cognitive dysfunction syndrome. The aim is to provide a broad overview of the current knowledge on canine and feline dementia. Experiences of clinicians are appropriately linked with current scientific knowledge in a readily comprehensible form. In the first three chapters we describe the clinical pictures of canine and feline dementia, discuss the medical causes of the disease and its phenotypic variability. In the 4th chapter we introduce the dog as an appropriate animal model for human Alzheimer’s disease progression. Then we shed light on the neuropathological hallmarks of canine and feline dementia. For the first time we touch upon the modern diagnostic approaches based on the neuroproteomic technological progress. Last but not least, we address the current pharmacological and non-pharmacological approaches for therapy and risk and protective factors of feline and canine dementia. The book addresses clinicians, researchers, university teachers and graduate students in veterinary neurology and medicine.

Canine and Feline Skin Cytology: A Comprehensive and Illustrated Guide to the Interpretation of Skin Lesions via Cytological Examination

by Francesco Albanese

This book discusses canine and feline skin cytology and the importance of this diagnostic tool in interpreting skin lesions. With more than 600 clinical and cytological color pictures, it explains the cytological patterns observed in all cutaneous inflammatory and neoplastic lesions in cats and dogs, as well as cutaneous metastasis of non-primary skin neoplasms. The first part of the book describes cell morphology and cytological patterns, providing an overview of the normal structure of the skin. In the second chapter, readers learn how to choose the best techniques for different types of lesions. Further chapters present the cytological findings in the main inflammatory and neoplastic skin diseases. By focusing on the macroscopic aspects of the lesions from which the cells are collected, it helps readers to interpret cytological specimens. The final chapter explores the cytology of cutaneous metastasis from internal organs or accessory glands. This book offers veterinary students and practitioners alike an essential diagnostic tool.

Canine Confidential: Why Dogs Do What They Do

by Marc Bekoff

For all the love and attention we give dogs, much of what they do remains mysterious. Just think about different behaviors you see at a dog park: We have a good understanding of what it means when dogs wag their tails—but what about when they sniff and roll on a stinky spot? Why do they play tug-of-war with one dog, while showing their bellies to another? Why are some dogs shy, while others are bold? What goes on in dogs’ heads and hearts—and how much can we know and understand? Canine Confidential has the answers. Written by award-winning scientist—and lifelong dog lover—Marc Bekoff, it not only brilliantly opens up the world of dog behavior, but also helps us understand how we can make our dogs’ lives the best they can possibly be. Rooted in the most up-to-date science on cognition and emotion—fields that have exploded in recent years—Canine Confidential is a wonderfully accessible treasure trove of new information and myth-busting. Peeing, we learn, isn’t always marking; grass-eating isn’t always an attempt to trigger vomiting; it’s okay to hug a dog—on their terms; and so much more. There’s still much we don’t know, but at the core of the book is the certainty that dogs do have deep emotional lives, and that as their companions we must try to make those lives as rich and fulfilling as possible. It’s also clear that we must look at dogs as unique individuals and refrain from talking about “the dog.” Bekoff also considers the practical importance of knowing details about dog behavior. He advocates strongly for positive training—there’s no need to dominate or shame dogs or to make them live in fear—and the detailed information contained in Canine Confidential has a good deal of significance for dog trainers and teachers. He also suggests that trainers should watch and study dogs in various contexts outside of those in which they are dealing with clients, canine and human, with specific needs. There’s nothing in the world as heartwarming as being greeted by your dog at the end of the workday. Read Canine Confidential, and you’ll be on the road to making your shared lives as happy, healthy, and rewarding as they can possibly be.

Canine Confidential: Why Dogs Do What They Do

by Marc Bekoff

For all the love and attention we give dogs, much of what they do remains mysterious. Just think about different behaviors you see at a dog park: We have a good understanding of what it means when dogs wag their tails—but what about when they sniff and roll on a stinky spot? Why do they play tug-of-war with one dog, while showing their bellies to another? Why are some dogs shy, while others are bold? What goes on in dogs’ heads and hearts—and how much can we know and understand? Canine Confidential has the answers. Written by award-winning scientist—and lifelong dog lover—Marc Bekoff, it not only brilliantly opens up the world of dog behavior, but also helps us understand how we can make our dogs’ lives the best they can possibly be. Rooted in the most up-to-date science on cognition and emotion—fields that have exploded in recent years—Canine Confidential is a wonderfully accessible treasure trove of new information and myth-busting. Peeing, we learn, isn’t always marking; grass-eating isn’t always an attempt to trigger vomiting; it’s okay to hug a dog—on their terms; and so much more. There’s still much we don’t know, but at the core of the book is the certainty that dogs do have deep emotional lives, and that as their companions we must try to make those lives as rich and fulfilling as possible. It’s also clear that we must look at dogs as unique individuals and refrain from talking about “the dog.” Bekoff also considers the practical importance of knowing details about dog behavior. He advocates strongly for positive training—there’s no need to dominate or shame dogs or to make them live in fear—and the detailed information contained in Canine Confidential has a good deal of significance for dog trainers and teachers. He also suggests that trainers should watch and study dogs in various contexts outside of those in which they are dealing with clients, canine and human, with specific needs. There’s nothing in the world as heartwarming as being greeted by your dog at the end of the workday. Read Canine Confidential, and you’ll be on the road to making your shared lives as happy, healthy, and rewarding as they can possibly be.

Canine Confidential: Why Dogs Do What They Do

by Marc Bekoff

For all the love and attention we give dogs, much of what they do remains mysterious. Just think about different behaviors you see at a dog park: We have a good understanding of what it means when dogs wag their tails—but what about when they sniff and roll on a stinky spot? Why do they play tug-of-war with one dog, while showing their bellies to another? Why are some dogs shy, while others are bold? What goes on in dogs’ heads and hearts—and how much can we know and understand? Canine Confidential has the answers. Written by award-winning scientist—and lifelong dog lover—Marc Bekoff, it not only brilliantly opens up the world of dog behavior, but also helps us understand how we can make our dogs’ lives the best they can possibly be. Rooted in the most up-to-date science on cognition and emotion—fields that have exploded in recent years—Canine Confidential is a wonderfully accessible treasure trove of new information and myth-busting. Peeing, we learn, isn’t always marking; grass-eating isn’t always an attempt to trigger vomiting; it’s okay to hug a dog—on their terms; and so much more. There’s still much we don’t know, but at the core of the book is the certainty that dogs do have deep emotional lives, and that as their companions we must try to make those lives as rich and fulfilling as possible. It’s also clear that we must look at dogs as unique individuals and refrain from talking about “the dog.” Bekoff also considers the practical importance of knowing details about dog behavior. He advocates strongly for positive training—there’s no need to dominate or shame dogs or to make them live in fear—and the detailed information contained in Canine Confidential has a good deal of significance for dog trainers and teachers. He also suggests that trainers should watch and study dogs in various contexts outside of those in which they are dealing with clients, canine and human, with specific needs. There’s nothing in the world as heartwarming as being greeted by your dog at the end of the workday. Read Canine Confidential, and you’ll be on the road to making your shared lives as happy, healthy, and rewarding as they can possibly be.

Canine Confidential: Why Dogs Do What They Do

by Marc Bekoff

For all the love and attention we give dogs, much of what they do remains mysterious. Just think about different behaviors you see at a dog park: We have a good understanding of what it means when dogs wag their tails—but what about when they sniff and roll on a stinky spot? Why do they play tug-of-war with one dog, while showing their bellies to another? Why are some dogs shy, while others are bold? What goes on in dogs’ heads and hearts—and how much can we know and understand? Canine Confidential has the answers. Written by award-winning scientist—and lifelong dog lover—Marc Bekoff, it not only brilliantly opens up the world of dog behavior, but also helps us understand how we can make our dogs’ lives the best they can possibly be. Rooted in the most up-to-date science on cognition and emotion—fields that have exploded in recent years—Canine Confidential is a wonderfully accessible treasure trove of new information and myth-busting. Peeing, we learn, isn’t always marking; grass-eating isn’t always an attempt to trigger vomiting; it’s okay to hug a dog—on their terms; and so much more. There’s still much we don’t know, but at the core of the book is the certainty that dogs do have deep emotional lives, and that as their companions we must try to make those lives as rich and fulfilling as possible. It’s also clear that we must look at dogs as unique individuals and refrain from talking about “the dog.” Bekoff also considers the practical importance of knowing details about dog behavior. He advocates strongly for positive training—there’s no need to dominate or shame dogs or to make them live in fear—and the detailed information contained in Canine Confidential has a good deal of significance for dog trainers and teachers. He also suggests that trainers should watch and study dogs in various contexts outside of those in which they are dealing with clients, canine and human, with specific needs. There’s nothing in the world as heartwarming as being greeted by your dog at the end of the workday. Read Canine Confidential, and you’ll be on the road to making your shared lives as happy, healthy, and rewarding as they can possibly be.

Canine Confidential: Why Dogs Do What They Do

by Marc Bekoff

For all the love and attention we give dogs, much of what they do remains mysterious. Just think about different behaviors you see at a dog park: We have a good understanding of what it means when dogs wag their tails—but what about when they sniff and roll on a stinky spot? Why do they play tug-of-war with one dog, while showing their bellies to another? Why are some dogs shy, while others are bold? What goes on in dogs’ heads and hearts—and how much can we know and understand? Canine Confidential has the answers. Written by award-winning scientist—and lifelong dog lover—Marc Bekoff, it not only brilliantly opens up the world of dog behavior, but also helps us understand how we can make our dogs’ lives the best they can possibly be. Rooted in the most up-to-date science on cognition and emotion—fields that have exploded in recent years—Canine Confidential is a wonderfully accessible treasure trove of new information and myth-busting. Peeing, we learn, isn’t always marking; grass-eating isn’t always an attempt to trigger vomiting; it’s okay to hug a dog—on their terms; and so much more. There’s still much we don’t know, but at the core of the book is the certainty that dogs do have deep emotional lives, and that as their companions we must try to make those lives as rich and fulfilling as possible. It’s also clear that we must look at dogs as unique individuals and refrain from talking about “the dog.” Bekoff also considers the practical importance of knowing details about dog behavior. He advocates strongly for positive training—there’s no need to dominate or shame dogs or to make them live in fear—and the detailed information contained in Canine Confidential has a good deal of significance for dog trainers and teachers. He also suggests that trainers should watch and study dogs in various contexts outside of those in which they are dealing with clients, canine and human, with specific needs. There’s nothing in the world as heartwarming as being greeted by your dog at the end of the workday. Read Canine Confidential, and you’ll be on the road to making your shared lives as happy, healthy, and rewarding as they can possibly be.

Canine Confidential: Why Dogs Do What They Do

by Marc Bekoff

For all the love and attention we give dogs, much of what they do remains mysterious. Just think about different behaviors you see at a dog park: We have a good understanding of what it means when dogs wag their tails—but what about when they sniff and roll on a stinky spot? Why do they play tug-of-war with one dog, while showing their bellies to another? Why are some dogs shy, while others are bold? What goes on in dogs’ heads and hearts—and how much can we know and understand? Canine Confidential has the answers. Written by award-winning scientist—and lifelong dog lover—Marc Bekoff, it not only brilliantly opens up the world of dog behavior, but also helps us understand how we can make our dogs’ lives the best they can possibly be. Rooted in the most up-to-date science on cognition and emotion—fields that have exploded in recent years—Canine Confidential is a wonderfully accessible treasure trove of new information and myth-busting. Peeing, we learn, isn’t always marking; grass-eating isn’t always an attempt to trigger vomiting; it’s okay to hug a dog—on their terms; and so much more. There’s still much we don’t know, but at the core of the book is the certainty that dogs do have deep emotional lives, and that as their companions we must try to make those lives as rich and fulfilling as possible. It’s also clear that we must look at dogs as unique individuals and refrain from talking about “the dog.” Bekoff also considers the practical importance of knowing details about dog behavior. He advocates strongly for positive training—there’s no need to dominate or shame dogs or to make them live in fear—and the detailed information contained in Canine Confidential has a good deal of significance for dog trainers and teachers. He also suggests that trainers should watch and study dogs in various contexts outside of those in which they are dealing with clients, canine and human, with specific needs. There’s nothing in the world as heartwarming as being greeted by your dog at the end of the workday. Read Canine Confidential, and you’ll be on the road to making your shared lives as happy, healthy, and rewarding as they can possibly be.

Canine Ergonomics: The Science of Working Dogs

by William S. Helton

Since Canis lupus familiaris first shared a fire with man more than 15,000 years ago, dogs have been trusted and valued coworkers. Yet the relatively new field of canine ergonomics is just beginning to unravel the secrets of this collaboration. As with many new fields, the literature on working dogs is scattered across several non-overlapping disci

Canine Olfaction Science and Law: Advances in Forensic Science, Medicine, Conservation, and Environmental Remediation

by Tadeusz Jezierski John Ensminger L. E. Papet

The value of the canine nose is well-documented, and working dogs are being utilized for their olfactory skills in an increasing number of fields. Not only are dogs used by police, security, and the military, but they are also now used in forensic science, in medical detection of disease, in calculating population trends of endangered species and e

Canine Parvovirus: A New Pathogen

by Cherelyn Vella S.W. Ketteridge

Canine parvovirus (CPV), a new virus of the Canidae first appeared during the 1970s, but disease caused by this virus was not reported until 1978. Then within a few months the virus crossed national and continental boundaries causing high fatality in domestic dog populations. A similar pattern of transmission was seen in sylvatic canines but infection was largely subclinical. Between 1979 and 1981 CPV was replaced worldwide by an antigenic variant designated CPV-2a. The epidemiological advantage of this variant over CPV is not understood. CPV is a new pathogen of dogs that has attracted an impressive body of research. However aspects of the biology of this virus remain unclear, not least of which is the questionof its possible origin. This book presents an up to date and comprehensive review of the natural history of CPV and its control by prophylactic vaccination. Particular attention is paid to the techniques used to examine the relationship between CPV and other parvoviruses. CPV is thought to be a variant of the virulent cat virus FPV (feline parvovirus) and at least one other variant is known MEV (mink enteritis virus). Theories on the genesis of CPV are discussed. An attempt to correlate the evidence and an hypothetical mechanism by which such a variant could have been selected is offered. This hypothesis is complemented by serological evidenceof CPV seroconversion in clinically normal dogs some years prior to the virulent pandemic. Many animal parvoviruses are known and in 1989/1990, no less than 6 new viruses were described. CPV may have arisen from an FPV vaccine strain. The use of modified live vaccines for the control of these viruses is questioned and alternative strategies discussed. A consise chapter on human parvoviruses describes the ever increasing role of B19 in human disease, including that of an opportunistic pathogen in AIDS patients.

Canines: The Original Biosensors

by Lauryn E. DeGreeff

Detection canines have been utilized throughout the world for over a century, and while numerous attempts have been made to replicate the canine’s ability to detect substances by mechanical means, none has been as successful. The olfactory system is a highly intricate and sophisticated design for chemical sensing, and the olfactory capacity of many animals, including canines, is considered unmatched by machine due to not only their great sensitivity and superior selectivity but also their trainability and mobility. These unique features have led to the use of such animals as "whole-animal" biosensors. Amplifying the benefits and diminishing the limitations of detection canines' interdisciplinary research is crucial to understanding canine olfaction and detection and enhancing this powerful and complex detector. The past 50 years have produced vast advancements in animal behavior/training technology to develop canines into more proficient and reliable sensors, while scientific research has provided tremendous support to help practitioners better understand how to utilize this powerful sensor. This book assembles a diverse group of authors with expertise in a variety of fields relating to detection canines and the chemical sensing industry, including both research and operational perspectives on detection canines. It illustrates how science enhances our understanding of how canines are employed for solving some of the world’s leading detection challenges.

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