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Deferring Development: Setting Aside Cells for Future Use in Development and Evolution (Evolutionary Cell Biology)

by Cory Douglas Bishop Brian K. Hall

This volume examines cells set aside during development for use later in ontogeny or in adult life. There is no single term for such cells. The cells explored fall within several major categories — stem cells, set-aside cells (in echinoderm larvae), imaginal discs in insects such as Drosophila, meristems (plants), blastemata (regeneration in amphibians), neoblasts (regeneration in planarians). The book compares and contrasts these cell types and the environments (niches) in which they operate with the aim of unravelling any relationships between them, between their activation in development, and in their evolution. Key Features Explores the nature of deferred-use cells in evolutionary and developmental context. Reviews the mechanisms of development of set-aside cells, such as stem cells, meristems, and imaginal discs. Provides phylogenetic overview of different types of deferred-use cells. Compares and contrasts different theories on the origin of deferred-use cells. Related Titles Calegari, F. & C. Waskow, eds. Stem Cells: From Basic Research to Therapy (ISBN 978-1-4822-0775-0) Cabral, J. M. S. & C. L. da Silva, eds. Bioreactors for Stem Cell Expansion and Differentiation (ISBN 978-1-4987-9590-6) Kong, H., A. J. Putnam, & L. B. Schook, eds. Stem Cells and Revascularization Therapies (ISBN 978-1-4398-0323-3) Schaffer, D., J. D. Bronzino, & D. R. Peterson, eds. Stem Cell Engineering: Principles and Practices (ISBN 978-1-4398-7204-8)

Deferring Development: Setting Aside Cells for Future Use in Development and Evolution (Evolutionary Cell Biology)

by Cory Douglas Bishop Brian K. Hall

This volume examines cells set aside during development for use later in ontogeny or in adult life. There is no single term for such cells. The cells explored fall within several major categories — stem cells, set-aside cells (in echinoderm larvae), imaginal discs in insects such as Drosophila, meristems (plants), blastemata (regeneration in amphibians), neoblasts (regeneration in planarians). The book compares and contrasts these cell types and the environments (niches) in which they operate with the aim of unravelling any relationships between them, between their activation in development, and in their evolution. Key Features Explores the nature of deferred-use cells in evolutionary and developmental context. Reviews the mechanisms of development of set-aside cells, such as stem cells, meristems, and imaginal discs. Provides phylogenetic overview of different types of deferred-use cells. Compares and contrasts different theories on the origin of deferred-use cells. Related Titles Calegari, F. & C. Waskow, eds. Stem Cells: From Basic Research to Therapy (ISBN 978-1-4822-0775-0) Cabral, J. M. S. & C. L. da Silva, eds. Bioreactors for Stem Cell Expansion and Differentiation (ISBN 978-1-4987-9590-6) Kong, H., A. J. Putnam, & L. B. Schook, eds. Stem Cells and Revascularization Therapies (ISBN 978-1-4398-0323-3) Schaffer, D., J. D. Bronzino, & D. R. Peterson, eds. Stem Cell Engineering: Principles and Practices (ISBN 978-1-4398-7204-8)

Defiant: The Untold Story of the Battle of Britain

by Robert Verkaik

'Robert Verkaik tells the story of the Battle of Britain's unlikeliest hero with verve and phenomenal grasp of detail. He brings the Defiant fighter back into focus as an important part of the victorious RAF in the hour of its greatest trial'Mark Urban'Meticulously researched and rich in human and social as well as military interest, Defiant fills a crucial gap in our understanding of that most perilous time' David Kynaston, author of Austerity Britain'Firmly establishes the aircraft's role in those crucial aerial battles of 1940 and elevates the brave aircrews who fought and died in their forgotten Defiants, to rank alongside their comrades in the better remembered Hurricanes and Spitfires.'David Fairhead, director of SpitfirePraise for Jihadi John:'An exemplary account . . . The book's most important contribution is to highlight the difficulties faced by the intelligence services . . . a first-class primer on Muslim extremism in Britain.'Max Hastings, Sunday Times'A riveting and compelling portrait of Mohammed Emwazi on his journey to the heart of darkness.'Andrew Hosken, author of Empire of Fear: Inside the Islamic StatePraise for Posh Boys:'The latest in the series of powerful books on the divisions in modern Britain, and will take its place on many bookshelves beside Reni Eddo-Lodge's Why I'm No Longer Talking to White People About Race and Owen Jones's Chavs.'Andrew Marr, Sunday Times'A trenchant j'accuse against the old-boy chumocracy . . . Posh Boys is, for a book about public schools, decidedly comprehensive.'Guardian'Inspired, committed, careful and kind.'Danny Dorling, author of Inequality and the 1%In this startling new perspective on the Battle of Britain, Robert Verkaik reveals the surprising truth about the battle's forgotten fighter, the Boulton Paul Defiant. The crucial role played by the Spitfire and the Hurricane has been exhaustively recorded, but, to date, next to nothing has been written about the third British fighter which took part in the battle. By writing from the unique perspective of the pilots who flew the Defiant and their air-gunners, Verkaik helps to set the record straight. The Air Staff regarded the Defiant as a state-of-the-art bomber destroyer and wanted to equip a third of all Fighter Command squadrons with this new plane. But the head of Fighter Command, Hugh Dowding, had other ideas and went to war with Whitehall over its plan to saddle him with hundreds of 'obsolete' turret fighters. Then at Dunkirk, a Defiant squadron scored a huge success against the Luftwaffe by shooting down more German planes in one day than any other RAF unit before or since. Fighter Command, enthusiastically urged on by the Air Ministry, now committed its third fighter to the coming air battle over southern England. In the desperate dogfights of the battle, Defiants shot down both German bombers and fighters but suffered heavy losses too - one squadron was almost wiped out when it was ambushed by a superior force of Messerschmitt 109s. On 30 August 1940 all Defiant squadrons were withdrawn from the front line. The families of the Defiant air crews believed that their husbands, brothers and sons had died in vain, but the truth is that their vital contribution to the battle over Dunkirk and their role in the Battle of Britain has been all but erased from the official history. The story of the Defiant has not been allowed to mar the glorious victory won by the Spitfire and the Hurricane. But Verkaik has uncovered new records, including top-secret memos written by Hugh Dowding and his deputy Keith Park as well as correspondence with the Air Staff, combat and squadron reports, pilot logs and recordings of the last interviews wi

Defiant Dreams: The Journey of an Afghan Girl Who Risked Everything for Education

by Sola Mahfouz Malaina Kapoor

'I began to grow up the day my mother warned me to stop laughing''Stories like this inspire me. Seeing the way people like Sola Mahfouz think about the world reinforces my optimism about the future.' BILL GATESAt age eleven, Sola Mahfouz was told she could no longer attend school. The Taliban threatened that any girl who dared to continue their education would have acid thrown in their face, be kidnapped, or worse. Confined to the walls of her home, Sola watched as the few freedoms of childhood were stripped away. She was forbidden to play, to sing, even to laugh. Her early teenage years were consumed by restrictions.Realising that she would have to either succumb to this life or find a way out, she decided on the latter. At age sixteen, without even a basic ability to add or subtract, she began secretly learning maths and English. By reading dictionaries and taking free online courses, she taught herself theoretical physics and philosophy, all from a home she could only leave five times a year. In the space of nine years she achieved the level of education that a westerner might take 25 years to do and against all odds moved to America to study quantum computing.It is a radical act to tell the story of an Afghan woman. Too often, they are portrayed only as victims, their identities erased by thick veils and blanket reporting. Defiant Dreams will change the narrative. It's the story of an Afghan girl who dared to ask for more.

Deficit Irrigation: A Remedy for Water Scarcity

by Abd El-Hafeez Zohry Samiha Ouda Tahany Noreldin

This book focuses on proving that deficit irrigation could play an important role in increasing food production in times of water scarcity. Although the application of deficit irrigation can involve loss in crop productivity, it still secures water to be use in cultivating more lands and producing more food. The following questions are discussed and the authors offer solutions to these problems:Will the production, on a national level, resulting from these new added areas compensate yield losses attained by application of deficit irrigation?Is it possible to use deficit irrigation practice to reduce the applied irrigation water to certain crops that have a surplus in their production, and direct this saved water to cultivate new areas with crops have low self-sufficiency ratios? Under climate change in 2030, would deficit irrigation practice have the same role it plays under the current conditions? This book will appeal to students and researchers involved with water scarcity and food security.

Deficits in EU and US Mandatory Environmental Information Disclosure: Legal, Comparative Legal and Economic Facets of Pollutant Release Inventories

by Dirk Bünger

It is the publicity about the Pollutant Release Inventory’s data which creates an incentive for firms to achieve emission reductions. Accordingly, public access to environmental information constitutes a core characteristic of the aforementioned inventory. Here, in essence, two facets arise. First, with regard to the collection, it is disputed whether such information, which may comprise confidential commercial and industrial information in the EU as well as trade secrets in the US, can be protected under fundamental and constitutional property rights respectively. Second, in the context of dissemination and utilisation, it is arguable whether the information indeed impacts polluters and produces an outcome that secures a certain level of environmental protection. The author responds to the first issue by taking the EU and US jurisdictions into account and strives to analyse how this novel form of Internet disclosure liberates market mechanisms in the quest for effective and efficient emission reductions.

Defining an Identity: The Evolution of Science Education as a Field of Research (Contemporary Trends and Issues in Science Education #20)

by P.J. Fensham

Research in science education is now an international activity. This book asks for the first time, Does this research activity have an identity? -It uses the significant studies of more than 75 researchers in 15 countries to see to what extent they provide evidence for an identity as a distinctive field of research. -It considers trends in the research over time, and looks particularly at what progression in the research entails. -It provides insight into how researchers influence each other and how involvement in research affects the being of the researcher as a person. -It addresses the relation between research and practice in a manner that sees teaching and learning in the science classroom as interdependent with national policies and curriculum traditions about science. It gives graduate students and other early researchers an unusual overview of their research area as a whole. Established researchers will be interested in, and challenged by, the identity the author ascribes to the research and by the plea he makes for the science content itself to be seen as problematic.

Defining Effective Transboundary Water Cooperation (Earthscan Studies in Water Resource Management)

by Melissa McCracken

This book establishes a framework for defining transboundary water cooperation and a methodology for evaluating its effectiveness, which will contribute to more effective and therefore successful cooperation processes. With the increasing focus on transboundary cooperation as a part of the Sustainable Development Goal Framework, there is global recognition of transboundary water cooperation as a tool for improved governance and management of transboundary surface and groundwaters. However, there is not an agreed upon definition of transboundary water cooperation in the literature or in practice. This book develops the Four Frames of Transboundary Water Cooperation, which is a neutral modular framework for developing context-specific explanatory definitions of transboundary water cooperation in basins and aquifers. The Four Frames of Cooperation are legal, institutional, relational, and outcome. However, we need to move beyond defining cooperation to understand better measures of the quality and effectiveness of cooperative processes. The Weighted Model of Effective Cooperation presents a first step in qualitatively evaluating the effectiveness of transboundary water cooperation. This model defines effective transboundary water cooperation and operationalizes a method to evaluate the effectiveness of cooperative processes over internationally shared waters. Effective cooperation emphasizes the relational and outcome frames of cooperation while working towards equitability and sustainability. Together, the Four Frames of Cooperation and the Weighted Model of Effective Cooperation will improve the understanding of cooperation and encourage a detailed evaluation of the quality, success, and effectiveness of cooperative processes. This book will be of great interest to students and scholars of water resource management, water governance, and environmental politics. It will also appeal to policymakers and professionals working in the fields of water conflict, water diplomacy, and international cooperation.

Defining Effective Transboundary Water Cooperation (Earthscan Studies in Water Resource Management)

by Melissa McCracken

This book establishes a framework for defining transboundary water cooperation and a methodology for evaluating its effectiveness, which will contribute to more effective and therefore successful cooperation processes. With the increasing focus on transboundary cooperation as a part of the Sustainable Development Goal Framework, there is global recognition of transboundary water cooperation as a tool for improved governance and management of transboundary surface and groundwaters. However, there is not an agreed upon definition of transboundary water cooperation in the literature or in practice. This book develops the Four Frames of Transboundary Water Cooperation, which is a neutral modular framework for developing context-specific explanatory definitions of transboundary water cooperation in basins and aquifers. The Four Frames of Cooperation are legal, institutional, relational, and outcome. However, we need to move beyond defining cooperation to understand better measures of the quality and effectiveness of cooperative processes. The Weighted Model of Effective Cooperation presents a first step in qualitatively evaluating the effectiveness of transboundary water cooperation. This model defines effective transboundary water cooperation and operationalizes a method to evaluate the effectiveness of cooperative processes over internationally shared waters. Effective cooperation emphasizes the relational and outcome frames of cooperation while working towards equitability and sustainability. Together, the Four Frames of Cooperation and the Weighted Model of Effective Cooperation will improve the understanding of cooperation and encourage a detailed evaluation of the quality, success, and effectiveness of cooperative processes. This book will be of great interest to students and scholars of water resource management, water governance, and environmental politics. It will also appeal to policymakers and professionals working in the fields of water conflict, water diplomacy, and international cooperation.

Defining Nature's Limits: The Roman Inquisition and the Boundaries of Science

by Neil Tarrant

A look at the history of censorship, science, and magic from the Middle Ages to the post-Reformation era. Neil Tarrant challenges conventional thinking by looking at the longer history of censorship, considering a five-hundred-year continuity of goals and methods stretching from the late eleventh century to well into the sixteenth. Unlike earlier studies, Defining Nature’s Limits engages the history of both learned and popular magic. Tarrant explains how the church developed a program that sought to codify what was proper belief through confession, inquisition, and punishment and prosecuted what they considered superstition or heresy that stretched beyond the boundaries of religion. These efforts were continued by the Roman Inquisition, established in 1542. Although it was designed primarily to combat Protestantism, from the outset the new institution investigated both practitioners of “illicit” magic and inquiries into natural philosophy, delegitimizing certain practices and thus shaping the development of early modern science. Describing the dynamics of censorship that continued well into the post-Reformation era, Defining Nature's Limits is revisionist history that will interest scholars of the history science, the history of magic, and the history of the church alike.

Defining Optimal Immunotherapies for Type 1 Diabetes: Novartis Foundation Symposium (Novartis Foundation Symposia #292)

by Novartis Foundation Symposium Staff Novartis Foundation Gregory R. Bock Jamie A. Goode

This book is a comprehensive and up-to-date account of where we stand in immunological strategies for preventing or treating type 1 diabetes (T1D). Brings together contributions from the leaders in the arena of clinical immunotherapy, not limited to the diabetes field exclusively, in order to delineate a road-map that would lead to future clinical trials. The book integrates information from human and animal studies. The book considers T1D within the broader context of autoimmune disease. The format contains several discussions, which address specific questions and provides guidelines for future strategies and solutions for discovering a cure.

Deflagration and Detonation Flame Arresters (A CCPS Concept Book #9)

by Stanley S. Grossel

Designed for chemical engineers and other technical personnel involved in the design, operation, and maintenance of facilities and equipment where deflagration and detonation flame arresters (DDFAs) may be required, this book fosters effective application and operation of DDFAs through treatment of their principles of operation, selection, installation, and maintenance methods. This reference covers a broad range of issues concerning DDAs, including: An overview of deflagration and detonation prevention and protection practices An overview of combustion and flame propagation and how DDAs halt propagation Deflagration and detonation flame arrester technology Installation in process systems Regulations, codes, and standards Illustrative examples, calculations, and guidelines for DDA selection Appendices, including a glossary, a flame arrester specification sheet for vendor quotation, and a listing of flame arrester manufacturers.

Defoaming: Theory and Industrial Applications (Surfactant Science #45)

by P. R. Garrett

Reviews all known antifoam mechanisms, and discusses the appropriate practical approaches for solving foam control problems in a variety of industrial contexts. These range from crude oil production to detergent formulation.

Defoaming: Theory and Industrial Applications (Surfactant Science #45)

by P R. Garrett

Reviews all known antifoam mechanisms, and discusses the appropriate practical approaches for solving foam control problems in a variety of industrial contexts. These range from crude oil production to detergent formulation.

Deforestation in the Teknaf Peninsula of Bangladesh: A Study of Political Ecology

by Masakazu Tani Md Abiar Rahman

This book presents a political ecology study on deforestation in the Teknaf Peninsula of Bangladesh. The study’s aim was to elucidate social factors contributing to processes of deforestation, including poverty, migration of refugees, forest encroachment, and power relations entailed in forest management. The individual analyses presented in the book are entirely based on primary information obtained through original field work conducted over a period of 7 years, and on remote sensing using satellite imagery and GIS techniques. The second half of the book considers reforestation approaches such as social and homestead forestry that have wider applications within developing countries.

Deformable Models: Theory and Biomaterial Applications (Topics in Biomedical Engineering. International Book Series)

by Aly Farag

This book covers the complete spectrum of deformable models, its evolution as an imagery field and its use in many biomedical engineering and clinical application disciplines. The book focuses on the core image processing techniques, theory and biomaterials useful to research and industry. Contributors are all pioneers in the field.

Deformable Models: Biomedical and Clinical Applications (Topics in Biomedical Engineering. International Book Series)

by Aly Farag

This book covers the complete spectrum of deformable models, its evolution as an imagery field and its use in many biomedical engineering and clinical application disciplines. It includes level sets, PDEs, curve and surface evolution and their applications in biomedical fields covering both static and motion imagery.

Deformable Registration Techniques for Thoracic CT Images: An Insight into Medical Image Registration

by Ali Imam Abidi S.K. Singh

This book focuses on novel approaches for thoracic computed tomography (CT) image registration and determination of respiratory motion models in a range of patient scenarios. It discusses the use of image registration processes to remove the inconsistencies between medical images acquired using different devices. In the context of comparative research and medical analysis, these methods are of immense value in image registration procedures, not just for thoracic CT images, but for all types of medical images in multiple modalities, and also in establishing a mean respiration motion model. Combined with advanced techniques, the methods proposed have the potential to advance the field of computer vision and help improve existing methods. The book is a valuable resource for those in the scientific community involved in modeling respiratory motion for a large number of people.

Deformation and Evolution of Life in Crystalline Materials: An Integrated Creep-Fatigue Theory

by Xijia Wu

This book walks you through the fundamental deformation and damage mechanisms. It lends the reader the key to open the doors into the maze of deformation/fracture phenomena under various loading conditions. Furthermore it provides the solution method to material engineering design and analysis problems, for those working in the aerospace, automotive or energy industries. The book introduces the integrated creep-fatigue theory (ICFT) that considers holistic damage evolution from surface/subsurface crack nucleation to propagation in coalescence with internally-distributed damage/discontinuities.

Deformation and Evolution of Life in Crystalline Materials: An Integrated Creep-Fatigue Theory

by Xijia Wu

This book walks you through the fundamental deformation and damage mechanisms. It lends the reader the key to open the doors into the maze of deformation/fracture phenomena under various loading conditions. Furthermore it provides the solution method to material engineering design and analysis problems, for those working in the aerospace, automotive or energy industries. The book introduces the integrated creep-fatigue theory (ICFT) that considers holistic damage evolution from surface/subsurface crack nucleation to propagation in coalescence with internally-distributed damage/discontinuities.

Deformation and Failure in Metallic Materials (Lecture Notes in Applied and Computational Mechanics #10)

by Kolumban Hutter Herbert Baaser

This book is devoted to the deformation and failure in metallic materials, summarizing the results of a research programme financed by the "Deutsche Forschungsgemeinschaft". It presents the recent engineering as well as mathematical key aspects of this field for a broad community. Its main focus is on the constitutive behaviour as well as the damage and fracture of metallic materials, covering their mathematical foundation, modelling and numerics, but also relevant experiments and their verification.

Deformation and Flow of Polymeric Materials

by Helmut Münstedt Friedrich Rudolf Schwarzl

This book describes the properties of single polymer molecules and polymeric materials and the methods how to characterize them. Molar masses, molar mass distributions and branching structure are discussed in detail. These properties are decisive for a deeper understanding of structure/properties relationships of polymeric materials. This book therefore describes and discusses them in detail. The mechanical behavior as a function of time and temperature is a key subject of the book. The authors present it on the basis of many original results they have obtained in their long research careers. They present the temperature dependence of mechanical properties of various polymeric materials in a wide temperature range: from cryogenic temperatures to the melt. Besides an extensive data collection on the transitions of various different polymeric materials, they also carefully present the physical explanations of the observed phenomena. Glass transition and melting temperatures are discussed, particularly, with their relevance for applications.A comprehensive part of the book deals with properties of polymers in the molten state and their decisive influence on the processing of the materials. The book presents and discusses viscous and elastic properties in detail as a function of molar mass, polydispersity, and branching. This book addresses students of polymer and materials science, as well as other natural sciences. Besides this educational value, it will also serve as a valuable monograph for everyone dealing with polymers and polymeric materials, from research, over development, to applications.

Deformation and Fracture Behaviour of Polymer Materials (Springer Series in Materials Science #247)

by Wolfgang Grellmann Beate Langer

This book covers the most recent advances in the deformation and fracture behaviour of polymer material. It provides deeper insight into related morphology–property correlations of thermoplastics, elastomers and polymer resins. Each chapter of this book gives a comprehensive review of state-of-the-art methods of materials testing and diagnostics, tailored for plastic pipes, films and adhesive systems as well as elastomeric components and others. The investigation of deformation and fracture behaviour using the experimental methods of fracture mechanics has been the subject of intense research during the last decade. In a systematic manner, modern aspects of fracture mechanics in the industrial application of polymers for bridging basic research and industrial development are illustrated by multifarious examples of innovative materials usage. This book will be of value to scientists, engineers and in polymer materials science.

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