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Biomaterial-Inspired Nanomedicines for Targeted Therapies
by Nagendra Singh Chauhan Madhulika Pradhan Krishna YadavThis book delves into the burgeoning field of nano-biomaterials and their application in targeted drug delivery across various therapeutic domains. Through its comprehensive exploration, it offers insights into the innovative approaches and potential of biomaterial-inspired nanomedicines in revolutionizing healthcare. Chapter 1 introduces readers to the fundamental concepts of biomaterial-inspired nanomedicines, laying the groundwork for subsequent discussions. Chapter 2 delves into the utilization of nano-biomaterials in tissue engineering, highlighting their role in regenerative medicine. The book further examines the targeting of specific physiological barriers, such as the blood-brain barrier (Chapter 3), and explores the opportunities and challenges in biomaterial-based vaccine delivery (Chapter 4). Additionally, it discusses the use of nano-biomaterials in addressing pulmonary obstruction (Chapter 5) and targeting the tumor microenvironment for chemotherapy (Chapter 6). Chapters 7 to 16 explore various therapeutic applications of nano-biomaterials across different medical conditions, including autoimmune skin disorders, diabetes, wound healing, central nervous system disorders, ocular diseases, infectious diseases, musculoskeletal disorders, and gastrointestinal diseases. Furthermore, the book sheds light on advances in nano-biomaterials for effective antimicrobial therapy and offers insights into the clinical and regulatory considerations associated with their use (Chapter 17). By encompassing a wide range of topics and providing in-depth analyses, "Biomaterial-Inspired Nanomedicines for Targeted Therapies" serves as a valuable resource for researchers, practitioners, and policymakers aiming to leverage the potential of nano-biomaterials in improving healthcare outcomes.
Biomaterial Mechanics
by Heather N. Hayenga Helim Aranda-EspinozaThis book describes the fundamental knowledge of mechanics and its application to biomaterials. An overivew of computer modeling in biomaterials is offered and multiple fields where biomaterials are used are reviewed with particular emphasis to the importance of the mechanical properties of biomaterials. The reader will obtain a better understanding of the current techniqus to synthesize, characterize and integrate biomaterials into the human body.
Biomaterial Mechanics
by Heather N. Hayenga Helim Aranda-EspinozaThis book describes the fundamental knowledge of mechanics and its application to biomaterials. An overivew of computer modeling in biomaterials is offered and multiple fields where biomaterials are used are reviewed with particular emphasis to the importance of the mechanical properties of biomaterials. The reader will obtain a better understanding of the current techniqus to synthesize, characterize and integrate biomaterials into the human body.
Biomaterialien und Biomineralisation: Eine Einführung für Naturwissenschaftler, Mediziner und Ingenieure (Teubner Studienbücher Chemie)
by Matthias EppleBiomaterialien ersetzen verloren gegangene Körperfunktionen, entweder allein oder in Kombination mit elektrischen oder elektronischen Bauteilen. Künstliche Haut, künstliche Adern, künstlicher Knochen, Hüftprothesen, Herzschrittmacher, Implantate, Zahnersatz: Alle diese Errungenschaften der modernen Medizin beruhen letztlich auf geeigneten Werkstoffen, die sowohl biologischen als auch chemischen und mechanischen Ansprüchen genügen müssen. Zur Entwicklung bedarf es der gemeinsamen Kompetenz von Medizinern, Chemikern, Physikern, Biologen und Ingenieuren. Das Buch soll in die notwendigen Grundlagen in einer für alle diese Ausbildungsrichtungen verständlichen Weise einführen.
Biomaterials
by S. V. BhatAs biomaterials are used in medical devices, meeting needs in such diverse surgical disciplines as ophthalmology, cardiology, neuromuscular surgery, orthopaedics, dentistry, etc., they must have intimate contact with patient's tissue or body fluids, providing a real physical interface which seriously restricts developments. This book is written for those who would like to advance their knowledge of biomaterials. The subject matter of the book is divided into twelve chapters dealing with the structure and relationship of biological and man-made biomaterials. The application of these materials for various medical devices, and recent developments in tissue engineering, are also discussed.
Biomaterials: Novel Materials from Biological Sources
by David ByromBiomaterials are produced from biological material and are used for their physical characteristics. This book looks at the range of biomaterials and their applications which range from the use of polysaccharides as thickening agents to the use of proteins as fibres and adhesives.
Biomaterials: A Basic Introduction
by Qizhi Chen George ThouasExplores Biomedical Science from a Unique PerspectiveBiomaterials: A Basic Introduction is a definitive resource for students entering biomedical or bioengineering disciplines. This text offers a detailed exploration of engineering and materials science, and examines the boundary and relationship between the two. Based on the author's course lectur
Biomaterials: From Molecules to Engineered Tissue (Advances in Experimental Medicine and Biology #553)
by Nesrin Hasirci Vasif HasirciBiomaterials: From Molecules to Engineered Tissue gives examples of the application areas of biomaterials involving molecules at one end of the spectrum and finished devices in the other. It covers molecular approaches as well as molecules functional in preparing and modifying biomaterials, medical devices and systems, tissue engineering and artificial organs. Chapters on biomedical informatics and ethics complement the design and production aspects with their contribution in informatics and ethical concerns of biomedical research. This is a reference book for the advanced graduate student eager to learn the biomaterials area and for all researchers working in medicine, pharmacy, engineering and basic sciences in universities, hospitals, and industry involved in biomaterials and biomedical device production.
Biomaterials: A Tantalus Experience (Biological and Medical Physics, Biomedical Engineering)
by Jozef A. Helsen Yannis MissirlisReplacement of a failing hip joint or other defective organs in the human body by artificial ‘spare parts’ has significantly improved our quality of life. These spare parts have to meet a wide spectrum of mechanical, chemical and design requirements. In this book, the properties and selection of materials for such `spare parts’ are deduced from case studies at the start of each chapter. Hard tissue replacements (joints, long bones, dental), soft tissue (heart valves) and tissue engineering are included. The chapters also detail the three generic classes of materials: alloys (including shape memory alloys), ceramics & glasses and polymers. Separate chapters are devoted to the toxicity of implants, the metals zirconium(-zirconium oxide), tantalum, niobium and metallic glasses, soluble metals and Rapid Prototyping techniques for the fabrication of custom made prostheses. The book concludes by a chapter on water as water is always ‘there’ and conditions the interaction between body and implant. Water is the very matrix of life on earth. A peculiarity of the book is its ‘perspective view’, meaning that the authors looked behind the present biomaterials’ décor and included historical backgrounds (real and mythological), future developments, and the relation to nature (plants and geology).
Biomaterials: An Introduction
by Roderic S. Lakes Joon B. ParkThis book is intended as a general introduction to the uses of artificial materials in the human body for the purposes of aiding healing, correcting deformities, and restoring lost function. It is an outgrowth of an undergraduate course for senior students in biomedical engineering, and it is offered as a text to be used in such courses. Topics include biocompatibility, techniques to minimize cor rosion or other degradation of implant materials, principles of materials science as it relates to the use of materials in the body, and specific uses of materials in various tissues and organs. It is expected that the student will have successively completed elementary courses in the mechanics of deformable bodies and in anatomy and physiology, and preferably also an introductory course in materials science prior to undertaking a course in biomaterials. Many quantitative examples are included as exercises for the engineering student. We recognize that many of these involve unrealistic simplifications and are limited to simple mechanical or chemical aspects of the implant problem. We offer as an apology the fact that biomaterials engineering is still to a great extent an empirical discipline that is complicated by many unknowns associated with the human body. In recognition of that fact, we have endeavored to describe both the successes and the failures in the use of materials in the human body. Also included are many photographs and illustrations of implants and devices as an aid to visualization.
Biomaterials: An Introduction
by J. ParkThis book is written for students who want a working knowledge in the field of implant materials. Obviously, the interdisciplinary nature of this subject has been a major obstacle in writing a book of this nature. In writing this book, I have attempted to cover both biological and nonbiological (man-made) materials for obvious reasons. Hence, this book can be divided into three parts-man-made materials, biological materials, and implant materials. The fundamental structure-property relationship is dealt with in the beginning, followed by the biological materials. Implant materials or biomaterials as such are not greatly different from other man-made materials. Therefore, their acceptability in the body is emphasized. In addition, the reasons for a particular implant design and its material selection have been given special attention. An effort is made to convert all the units into SI units although one or 10 two exceptions are made such as A (= 10- m). Also some abbreviations such as vlo (volume %) and wlo (weight %) are used for brevity. To cover the wide range of subjects dealt with in this book, I have used countless original and review articles as well as my own research proposals. A conscientious effort has been made to give credit to the original sources. Credit is given in the captions ofthe illustrations. For the occasional oversight of some tables and figures which could not be traced, the author offers his apologies.
Biomaterials: Principles and Applications
by Joon B. Park Joseph D. BronzinoBiomaterials: Principles and Applications offers a comprehensive review of all the major biomaterials in this rapidly growing field. In recent years, the role of biomaterials has been influenced considerably by advances in many areas of biotechnology and science, as well as advances in surgical techniques and instruments. Comprising chapters
Biomaterials: An Introduction
by Joon Park R. S. LakesWith sixty years of combined experience, the authors of this extensively revised book have learned to emphasize the fundamental materials science, structure-property relationships, and biological responses as a foundation for a wide array of biomaterials applications. This edition includes a new chapter on tissue engineering and regenerative medicine, approximately 1900 references to additional reading, extensive tutorial materials on new developments in spinal implants and fixation techniques and theory. It also offers systematic coverage of orthopedic implants, and expanded treatment of ceramic materials and implants.
Biomaterials: A Nano Approach
by Seeram RamakrishnaThere are several well-known books on the market that cover biomaterials in a general way, but none provide adequate focus on the future of and potential for actual uses of emerging nanontechnology in this burgeoning field.Biomaterials: A Nano Approach is written from a multi-disciplinary point of view that integrates aspects of materials science a
Biomaterials: Proceedings of a Workshop on the Status of Research and Training in Biomaterials held at the University of Illinois at the Medical Center and at the Chicago Circle, April 5–6, 1968
by L. StarkEssentially three groups of research workers are con cerned with biomaterials. The biophysicists, the biochemists and some bioengineers (particularly the metallurgists) are engaged in a study of the basic properties of engineering materials suitable for medical use and of biological mate rials. The bioengineers in general as part of a team are engaged in developing new devices suitable for medical pur poses including implantable devices; spectacular examples of such devices are artificial kidney and mechanical heart. The medical people, dentists, surgeons and others, play an impor tant role in developing criterions for the biomaterials, in the eValuation of such materials in physiological environment and as consumers of biomaterials. This workshop was an effort to bring together representatives of the above groups to ex change experiences and viewpoints in regard to both research and training in this rapidly developing and vital area. The individual presentations are some typical examples of biomaterials research. There are numerous other examples but basically they fall into three categories: materials in medicine, biological materials, and semi-artificial materials derived from biological sources. As a whole, the book pro vides a comprehensive but not exhaustive picture of the present state of affairs in the field of biomaterials. To the educators the discussion on training should be of par ticular interest. Those concerned with scientific adminis trations and policy would find the section on the interaction between government, industry and university very valuable.
Biomaterials
by Joyce Y. Wong Joseph D. BronzinoFor medical devices that must be placed inside the body, the right choice of material is the most important aspect of design. To ensure such devices are safe, reliable, economical, and biologically and physiologically compatible, the modern biomedical engineer must have a broad knowledge of currently available materials and the properties that affe
Biomaterials
by Joyce Y. Wong Joseph D. BronzinoFor medical devices that must be placed inside the body, the right choice of material is the most important aspect of design. To ensure such devices are safe, reliable, economical, and biologically and physiologically compatible, the modern biomedical engineer must have a broad knowledge of currently available materials and the properties that affe
Biomaterials: Principles and Practices
by Joyce Y. Wong Joseph D. Bronzino Donald R. PetersonMost current applications of biomaterials involve structural functions, even in those organs and systems that are not primarily structural in their nature, or very simple chemical or electrical functions. Complex chemical functions, such as those of the liver, and complex electrical or electrochemical functions, such as those of the brain and sense
Biomaterials and Biopolymers (AAPS Introductions in the Pharmaceutical Sciences #7)
by Avi Domb Boaz Mizrahi Shady FarahThis book is written to serve as textbook on biomaterials and biopolymers for faculty and students and thus contains a broad introduction and basic terms, followed by major developments over the years with some emphasis on recent developments and future prospects. It provide a comprehensive overview in biomaterials and biopolymers. All relevant aspects of modern biomaterials, including: synthesis and characterization, biocompatibility and host response, the implementation of novel manufacturing processes, and advanced medical and biotechnological applications. Each chapter provides an overview of a specific field, its importance, the chemistry of biomaterials and the relations between chemical structure and the applications. Each chapter ends with a future prospective/concepts and a friendly quiz/multiple answer questions with answers that serves as a resource to provide guided additional practice.
Biomaterials and Immune Response: Complications, Mechanisms and Immunomodulation (Devices, Circuits, and Systems)
by Nihal Engin VranaThe interactions of the biomaterials with the host immune system is crucial for their functionality. This book aims to provide the reader with a better understanding of the role of the immune system in biomaterial applications. For this end, the book has dedicated chapters for i) explaining immune cells taking part in immune response to biomaterials/immune systems interface; ii) the effect of biomaterial shape, form and physicochemical properties on the response of immune system; iii) biofilm formation on implanted materials as a failure of immune system/biomaterial interactions; iv) tissue-specific effects of immune response and its consequences for tissue engineering and regenerative medicine; v) immune reaction in a clinical context (periodontology). In the field of biomaterials there are significant advances in using immunomodulation techniques to improve the success rates of implantable materials. For better understanding of such techniques it is required to have a full grasp of the biomaterial–immune system interactions. This would greatly enhance the understanding of why the human body reacts to implants in a certain way and how to improve the clinical outcomes by developing immune-instructive biomaterials. Provides keen insight into biomaterial–immune cell interactions Presents an explanation of state-of-the-art methodologies in immunomodulation Offers a concise and simple-to-understand treatment of biomaterial–immune cell interactions for materials scientists in a biology heavy topic Explores a comprehensive overview of biomaterial related complications Provides extensive references at the end of each chapter to enhance study for this very hot research area
Biomaterials and Immune Response: Complications, Mechanisms and Immunomodulation (Devices, Circuits, and Systems)
by Nihal Engin VranaThe interactions of the biomaterials with the host immune system is crucial for their functionality. This book aims to provide the reader with a better understanding of the role of the immune system in biomaterial applications. For this end, the book has dedicated chapters for i) explaining immune cells taking part in immune response to biomaterials/immune systems interface; ii) the effect of biomaterial shape, form and physicochemical properties on the response of immune system; iii) biofilm formation on implanted materials as a failure of immune system/biomaterial interactions; iv) tissue-specific effects of immune response and its consequences for tissue engineering and regenerative medicine; v) immune reaction in a clinical context (periodontology). In the field of biomaterials there are significant advances in using immunomodulation techniques to improve the success rates of implantable materials. For better understanding of such techniques it is required to have a full grasp of the biomaterial–immune system interactions. This would greatly enhance the understanding of why the human body reacts to implants in a certain way and how to improve the clinical outcomes by developing immune-instructive biomaterials. Provides keen insight into biomaterial–immune cell interactions Presents an explanation of state-of-the-art methodologies in immunomodulation Offers a concise and simple-to-understand treatment of biomaterial–immune cell interactions for materials scientists in a biology heavy topic Explores a comprehensive overview of biomaterial related complications Provides extensive references at the end of each chapter to enhance study for this very hot research area
Biomaterials and Materials for Medicine: Innovations in Research, Devices, and Applications (Emerging Materials and Technologies)
by Jingan LiBiomaterials and Materials for Medicine: Innovations in Research, Devices, and Applications provides an application-oriented summary of innovations in this rapidly evolving field, offering a view of various directions in biomaterials and medical materials and their advanced uses. Highlights vascular, orthopedic, skin tissue engineering, and nerve tissue engineering biomaterials, including the latest research on therapeutic devices and implants Introduces special stent materials for palliative treatment of esophageal cancer and related technologies of surface modification Discusses use of biomaterials and related designs in drug targeting and controlled release Describes wearable biomedical devices, biomimetic materials, and micronscale and nanoscale biomaterials Details the theoretical calculation and computer simulation of biomaterials as a complementary discipline with physical experimental science This book is aimed at an interdisciplinary group of researchers working on development and application of biomaterials for medical applications in the fields of materials scientists, biomedical engineering, and medicine.
Biomaterials and Materials for Medicine: Innovations in Research, Devices, and Applications (Emerging Materials and Technologies)
by Jingan LiBiomaterials and Materials for Medicine: Innovations in Research, Devices, and Applications provides an application-oriented summary of innovations in this rapidly evolving field, offering a view of various directions in biomaterials and medical materials and their advanced uses. Highlights vascular, orthopedic, skin tissue engineering, and nerve tissue engineering biomaterials, including the latest research on therapeutic devices and implants Introduces special stent materials for palliative treatment of esophageal cancer and related technologies of surface modification Discusses use of biomaterials and related designs in drug targeting and controlled release Describes wearable biomedical devices, biomimetic materials, and micronscale and nanoscale biomaterials Details the theoretical calculation and computer simulation of biomaterials as a complementary discipline with physical experimental science This book is aimed at an interdisciplinary group of researchers working on development and application of biomaterials for medical applications in the fields of materials scientists, biomedical engineering, and medicine.
Biomaterials and Medical Devices: A Perspective from an Emerging Country (Advanced Structured Materials #58)
by Ferdiansyah Mahyudin Hendra HermawanThis book presents an introduction to biomaterials with the focus on the current development and future direction of biomaterials and medical devices research and development in Indonesia. It is the first biomaterials book written by selected academic and clinical experts experts on biomaterials and medical devices from various institutions and industries in Indonesia. It serves as a reference source for researchers starting new projects, for companies developing and marketing products and for governments setting new policies.Chapter one covers the fundamentals of biomaterials, types of biomaterials, their structures and properties and the relationship between them. Chapter two discusses unconventional processing of biomaterials including nano-hybrid organic-inorganic biomaterials. Chapter three addresses biocompatibility issues including in vitro cytotoxicity, genotoxicity, in vitro cell models, biocompatibility data and its related failure. Chapter four describes degradable biomaterial for medical implants, which include biodegradable polymers, biodegradable metals, degradation assessment techniques and future directions. Chapter five focuses on animal models for biomaterial research, ethics, care and use, implantation study and monitoring and studies on medical implants in animals in Indonesia. Chapter six covers biomimetic bioceramics, natural-based biocomposites and the latest research on natural-based biomaterials in Indonesia. Chapter seven describes recent advances in natural biomaterial from human and animal tissue, its processing and applications. Chapter eight discusses orthopedic applications of biomaterials focusing on most common problems in Indonesia, and surgical intervention and implants. Chapter nine describes biomaterials in dentistry and their development in Indonesia.
Biomaterials- and Microfluidics-Based Tissue Engineered 3D Models (Advances in Experimental Medicine and Biology #1230)
by J. Miguel Oliveira Rui L. ReisThis contributed volume reviews the latest advances on relevant 3D tissue engineered in vitro models of disease making use of biomaterials and microfluidics. The main focus of this book is on advanced biomaterials and microfluidics technologies that have been used in in vitro mimetic 3D models of human diseases and show great promise in revolutionizing personalized medicine. Readers will discover important topics involving biomaterials and microfluidics design, advanced processing techniques, and development and validation of organ- and body-on-a-chip models for bone, liver, and cancer research. An in depth discussion of microfabrication methods for microfluidics development is also provided. This work is edited by two truly multidisciplinary scientists and includes important contributions from well-known experts in their fields. The work is written for both early stage and experienced researchers, and well-established scientists enrolled in the fields of biomaterials, microfluidics, and tissue engineering, and is especially suited to those who wish to become acquainted with the principles and latest developments of in vitro models of diseases, such as professionals working in pharma, medicine, and engineering.