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Bioprocessing Piping and Equipment Design: A Companion Guide for the ASME BPE Standard (Wiley-ASME Press Series)

by William M. Huitt

The only comprehensive and authoritative reference guide to the ASME Bioprocessing Piping and Equipment (BPE) standard This is a companion guide to the ASME Bioprocessing Piping and Equipment (BPE) Standard and explains what lies behind many of the requirements and recommendations within that industry standard. Following an introductory narrative to the Standard's early history, industry related codes and standards are explained; the design and engineering aspects cover construction materials, both metallic and nonmetallic; then components, fabrication, assembly and installation of piping systems are explored. Examination, Inspection and Testing then precede the ASME BPE certification process, concluding with a discussion on system design. The author draws on many years' experience and insights from first-hand involvement in the field of industrial piping design, engineering, construction, and management, which includes the bioprocessing industry. The reader will learn why dimensions and tolerances, process instrumentation, and material selection play such an integral part in the manufacture of components and instrumentation. This easy to understand and navigate guide will assist engineers (design, piping, chemical, etc.) who need to understand the basis for much of the Standard’s content, as do the contractors and inspectors who have to meet and validate compliance with the BPE Standard.

Bioprocessing Piping and Equipment Design: A Companion Guide for the ASME BPE Standard (Wiley-ASME Press Series)

by William M. Huitt

The only comprehensive and authoritative reference guide to the ASME Bioprocessing Piping and Equipment (BPE) standard This is a companion guide to the ASME Bioprocessing Piping and Equipment (BPE) Standard and explains what lies behind many of the requirements and recommendations within that industry standard. Following an introductory narrative to the Standard's early history, industry related codes and standards are explained; the design and engineering aspects cover construction materials, both metallic and nonmetallic; then components, fabrication, assembly and installation of piping systems are explored. Examination, Inspection and Testing then precede the ASME BPE certification process, concluding with a discussion on system design. The author draws on many years' experience and insights from first-hand involvement in the field of industrial piping design, engineering, construction, and management, which includes the bioprocessing industry. The reader will learn why dimensions and tolerances, process instrumentation, and material selection play such an integral part in the manufacture of components and instrumentation. This easy to understand and navigate guide will assist engineers (design, piping, chemical, etc.) who need to understand the basis for much of the Standard’s content, as do the contractors and inspectors who have to meet and validate compliance with the BPE Standard.

Bioprocessing Technologies in Biorefinery for Sustainable Production of Fuels, Chemicals, and Polymers

by Shang-Tian Yang Hesham El-Ensashy Nuttha Thongchul

Sets the stage for large-scale production of biofuels and bio-based chemicals In response to diminishing supplies as well as the environmental hazards posed by fossil fuels and petrochemicals, interest and demand for green, sustainable biofuels and bio-based chemicals are soaring. Biomass may be the solution. It is an abundant carbon-neutral renewable feedstock that can be used for the production of fuels and chemicals. Currently, biorefineries use corn, soybeans, and sugarcane for bioethanol and biodiesel production; however, there are many challenges facing biorefineries, preventing biomass from reaching its full potential. This book provides a comprehensive review of bioprocessing technologies that use lignocellulosic biomass for the production of biofuels, biochemicals, and biopolymers. It begins with an overview of integrated biorefineries. Next, it covers: Biomass feedstocks, including sugar, starch, oil, and energy crops as well as microalgae Pretreatment technologies for lignocellulosic biomass Hydrolytic enzymes used in biorefineries for the hydrolysis of starch and lignocelluloses Bioconversion technologies for current and future biofuels such as ethanol, biodiesel, butanol, hydrogen, and biogas Specialty chemicals, building block chemicals, and biopolymers produced via fermentation Phytochemicals and functional food ingredients extracted from plant materials All the chapters have been written and edited by leading experts in bioprocessing and biorefining technologies. Contributions are based on a thorough review of the literature as well as the authors' firsthand experience developing and working with bioprocessing technologies. By setting forth the current state of the technology and pointing to promising new directions in research, Bioprocessing Technologies in Biorefinery for Sustainable Production of Fuels, Chemicals, and Polymers will enable readers to move towards large-scale, sustainable, and economical production of biofuels and bio-based chemicals.

Bioprocessing Technologies in Biorefinery for Sustainable Production of Fuels, Chemicals, and Polymers: In Biorefinery For Sustainable Production Of Fuels, Chemicals, And Polymers

by Shang-Tian Yang Hesham A. El-Enshasy Nuttha Thongchul

Sets the stage for large-scale production of biofuels and bio-based chemicals In response to diminishing supplies as well as the environmental hazards posed by fossil fuels and petrochemicals, interest and demand for green, sustainable biofuels and bio-based chemicals are soaring. Biomass may be the solution. It is an abundant carbon-neutral renewable feedstock that can be used for the production of fuels and chemicals. Currently, biorefineries use corn, soybeans, and sugarcane for bioethanol and biodiesel production; however, there are many challenges facing biorefineries, preventing biomass from reaching its full potential. This book provides a comprehensive review of bioprocessing technologies that use lignocellulosic biomass for the production of biofuels, biochemicals, and biopolymers. It begins with an overview of integrated biorefineries. Next, it covers: Biomass feedstocks, including sugar, starch, oil, and energy crops as well as microalgae Pretreatment technologies for lignocellulosic biomass Hydrolytic enzymes used in biorefineries for the hydrolysis of starch and lignocelluloses Bioconversion technologies for current and future biofuels such as ethanol, biodiesel, butanol, hydrogen, and biogas Specialty chemicals, building block chemicals, and biopolymers produced via fermentation Phytochemicals and functional food ingredients extracted from plant materials All the chapters have been written and edited by leading experts in bioprocessing and biorefining technologies. Contributions are based on a thorough review of the literature as well as the authors' firsthand experience developing and working with bioprocessing technologies. By setting forth the current state of the technology and pointing to promising new directions in research, Bioprocessing Technologies in Biorefinery for Sustainable Production of Fuels, Chemicals, and Polymers will enable readers to move towards large-scale, sustainable, and economical production of biofuels and bio-based chemicals.

Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts (Wiley Series in Biotechnology and Bioengineering)

by Claire Komives

Written for industrial and academic researchers and development scientists in the life sciences industry, Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts is a guide to the tools, approaches, and useful developments in bioprocessing. This important guide: • Summarizes state-of-the-art bioprocessing methods and reviews applications in life science industries • Includes illustrative case studies that review six milestone bio-products • Discuses a wide selection of host strain types and disruptive bioprocess technologies

Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts (Wiley Series in Biotechnology and Bioengineering)

by Claire Komives Weichang Zhou

Written for industrial and academic researchers and development scientists in the life sciences industry, Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts is a guide to the tools, approaches, and useful developments in bioprocessing. This important guide: • Summarizes state-of-the-art bioprocessing methods and reviews applications in life science industries • Includes illustrative case studies that review six milestone bio-products • Discuses a wide selection of host strain types and disruptive bioprocess technologies

Bioprocessing Technology in Food and Health: Potential Applications And Emerging Scope

by Deepak Kumar Verma Prem Prakash Srivastav Ami R. Patel

The functional foods market represents one of the fastest growing and most fascinating areas of investigation and innovation in the food sector. This new volume focuses on recent findings, new research trends, and emerging technologies in bioprocessing: making use of microorganisms in the production of food with health and nutritional benefits. The volume is divided into three main parts. Part I discusses functional food production and human health, looking at some newly emerged bioprocessing technological advances in the functional foods (chocolates, whey beverages) in conjunction their prospective health benefits. Part II, on emerging applications of microorganism in safe food production, covers recent breakthroughs in food safety in microbial bioprocessing. Chapters discuss spoilage issues, harmful/pathogenic microorganisms, genetically modified microorganisms, stability and functionality, and potential of food-grade microbes for biodegradation of toxic compounds, such as mycotoxins, pesticides, and polycyclic hydrocarbons. Chapters in Part III, on emerging scope and potential application in the dairy and food industry, explore and investigate the current shortcomings and challenges of the microbially mediated processes at the industrial level. The editors have brought together a group of outstanding international contributors at the forefront of bioprocessing technology to produce a valuable resource for researchers, faculty, students, food nutrition and health practitioners, and all those working in the dairy, food, and nutraceutical industries, especially in the development of functional foods.

Bioprocessing Technology in Food and Health: Potential Applications and Emerging Scope

by Deepak Kumar Verma Prem Prakash Srivastav Ami R. Patel

The functional foods market represents one of the fastest growing and most fascinating areas of investigation and innovation in the food sector. This new volume focuses on recent findings, new research trends, and emerging technologies in bioprocessing: making use of microorganisms in the production of food with health and nutritional benefits. The volume is divided into three main parts. Part I discusses functional food production and human health, looking at some newly emerged bioprocessing technological advances in the functional foods (chocolates, whey beverages) in conjunction their prospective health benefits. Part II, on emerging applications of microorganism in safe food production, covers recent breakthroughs in food safety in microbial bioprocessing. Chapters discuss spoilage issues, harmful/pathogenic microorganisms, genetically modified microorganisms, stability and functionality, and potential of food-grade microbes for biodegradation of toxic compounds, such as mycotoxins, pesticides, and polycyclic hydrocarbons. Chapters in Part III, on emerging scope and potential application in the dairy and food industry, explore and investigate the current shortcomings and challenges of the microbially mediated processes at the industrial level. The editors have brought together a group of outstanding international contributors at the forefront of bioprocessing technology to produce a valuable resource for researchers, faculty, students, food nutrition and health practitioners, and all those working in the dairy, food, and nutraceutical industries, especially in the development of functional foods.

Bioproducts From Canada's Forests: New Partnerships in the Bioeconomy

by Suzanne Wetzel Luc C. Duchesne Michael F. Laporte

For the first time, this opportune book provides a comprehensive treatment of the many innovative, non-timber bioproducts that may be derived from Canada’s vast forests, including their potential economic, social and environmental impacts. It also offers a balanced discussion of the technological, policy and regulatory issues surrounding the emerging global bioeconomy. This book will not only be of interest to Canadian forestry professionals and entrepreneurs, but also to those interested in the contribution of forestry to the bioeconomy worldwide.

Bioprospecting Algae for Nanosized Materials (Nanotechnology in the Life Sciences)

by Jeyabalan Sangeetha Ram Prasad Devarajan Thangadurai

Algae are simple, primitive, heterogeneous, autotrophic, eukaryotic or prokaryotic organisms that lead a symbiotic, parasitic or free-living mode of life. Microalgae and macroalgae possess great potential in various fields of application. Microalgae are ubiquitous and extremely diverse microorganisms that can accumulate toxic contaminants and heavy metals from wastewater, making them a superior candidate to become a powerful nanofactory. Algae were discovered to reduce the presence of metal ions, and afterwards aid in the biosynthesis of nanoparticles. Since algae-mediated biogenic nanoparticles are eco-friendly, cost-effective, high-yielding, speedy and energy-efficient, a large number of studies have been published on them in the last few years. This book focuses on recent progress on the utilization of algae for the synthesis of nanoparticles, their characterization and the possible mechanisms involved. Bioprospecting Algae for Nanosized Materials describes the synthesis of algal nanomaterials and its application in various fields for sustainable development. This book outlines the procedures to prepare phyconanomaterials, techniques to utilize the nanomaterials, and applications in agriculture, environment and medicine.

Bioprospecting of Enzymes in Industry, Healthcare and Sustainable Environment

by Hrudayanath Thatoi Sonali Mohapatra Swagat Kumar Das

The rapid urbanization and industrialization of developing countries across the globe have necessitated for substantial resource utilization and development in the areas of Healthcare, Environment, and Renewable energy. In this context ,this resourceful book serves as a definitive source of information for the recent developments in application of microbial enzymes in various sectors. It covers applications in fermentation processes and their products, extraction and utilisation of enzymes from various sources and their application in health and biomass conversion for production of value added products. Different chapters discuss various areas of bioprospecting in enzyme technology, and describe why these are the mainstays for industrial production of value added products. The rich compilation of the cutting-edge advances and applications of the modern industrial based techniques hold feasible solutions for a range of current issues in enzyme technology.This book will be of particular interest for scientists, academicians, technical resource persons, engineers and members of industry. Undergraduate and graduate students pursuing courses in the area of industrial biotechnology will find the information in the book valuable. General readers having interest towards biofuels, enzyme technology, fermented food and value added products, phytochemicals and phytopharmaceutical products will also find the book appealing. Readers will discover modern concepts of enzymatic bioprocess technology for production of therapeutics and industrial value added products.

Bioprospecting of Microbial Resources for Agriculture, Environment and Bio-chemical Industry

by Pragya Mishra Pinki Saini

Recent years have seen a sharp rise in novel resistant pathogenic microorganisms. Bioprospecting, or the systematic identification, evaluation and exploitation of the diversity of life in a certain place, is a means of mining microorganisms for what is known as exploitable biology, or valuable genetic information. This information can then be used in the development of novel antibiotics, enzymes, food sources, and energy sources, all of which are of pressing industrial interest across agricultural, nutraceutical, pharmaceutical, biomedical and bioenergetic fields. Microbe-derived bioactive compounds are currently of significant use to the development of sustainable approaches in environmental protection efforts. However, production challenges currently pose a barrier to the large-scale commercialization of microbe-derived products. Bioprospecting of Microbial Resources for Agriculture, Environment and Bio-Chemical Industry is a much-needed review of the current achievements and emerging challenges facing the field of microbe-derived compound production. It covers established knowledge while also proposing solutions to various limitations,and introducing the application of microbe-based products in pollution control and the development of greener technologies. As the preservation of global biodiversity and the production of novel antibiotics are both of significant importance to researchers and the general public alike, this text offers a timely and comprehensive look into the many uses of microbial products across industries. Specific uses covered in the text include the microbial-based recovery of metals for e-waste, the use of microbial nanowires in bioenergy applications, and omics-based technologies in bioprospecting.Through a comprehensive investigation into the current and emerging research on microbial bioprospecting, this text will expand possibilities for the application of microbial resources nutraceutical, pharmaceutical, biomedical and bioenergetic fields. It offers valuable insights for administrators, policy makers, and consultants. It is also a helpful guide for researchers and students in the areas of microbiology, microbial prospecting, food and plant biotechnology, industrial microbiology, biochemical engineering and environmental science.

Bioprospecting of Tropical Medicinal Plants

by Karuppusamy Arunachalam Xuefei Yang Sreeja Puthanpura Sasidharan

This book focuses on natural products, in particular medicinal plants and their derived products, as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery . There are several advantages for plant-derived therapeutics, including wide availability, diverse pharmacological actions, and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying the efficacy and safety of medicinal plants and phytochemicals in treating human diseases. A plethora of basic studies has also unraveled molecular mechanisms underlying the health benefits of herbal medicines. Nevertheless, issues such as identification of bioactive ingredients, standardization of the products, and drug interactions remain to be systematically documented. Bioprospecting of Tropical Medicinal Plants represents a comprehensive analysis of natural products, mainly medicinal plants and phytochemicals. It includes detailed medicinal properties and pharmacological action from in vitro models to clinical trials. The goal is to present the readers a carefully curated collection of plant-derived natural products and their underlying molecular mechanisms.

Bioprospection of Co-products and Agro-industrial Wastes: A Sustainable Biotechnological Approach

by Joilane Alves Pereira Freire Stella Regina Arcanjo Medeiros Jailane De Souza Aquino Chistiane Mendes Feitosa Mahendra Rai

The proposed book titled as “Bioprospection of Coproducts and Agro-industrial Wastes: A Sustainable Biotechnological Approach”, seeks to offer the importance of the recycling, reuse of food residue, byproducts of fruits and agri-wastes to the academic community and industries. In developing countries facing malnutrition and environmental problems, this book would be very useful. The food waste and the residues resulting from this process are now becoming environmental problems. These mainly include leaves, stems, seeds, bark, and roots that have high nutritional value, many times even greater than the part usually consumed. It is a pressing priority to reuse and recycle the waste which is detrimental to the environment. This book would be an essential reading for students, researchers, and people from the food and pharma industry.

Bioprospection of Co-products and Agro-industrial Wastes: A Sustainable Biotechnological Approach

by Joilane Alves Pereira Freire Stella Regina A. Medeiros Jailane de Souza Aquino Chistiane M. Feitosa Mahendra Rai

The proposed book titled as “Bioprospection of Coproducts and Agro-industrial Wastes: A Sustainable Biotechnological Approach”, seeks to offer the importance of the recycling, reuse of food residue, byproducts of fruits and agri-wastes to the academic community and industries. In developing countries facing malnutrition and environmental problems, this book would be very useful. The food waste and the residues resulting from this process are now becoming environmental problems. These mainly include leaves, stems, seeds, bark, and roots that have high nutritional value, many times even greater than the part usually consumed. It is a pressing priority to reuse and recycle the waste which is detrimental to the environment. This book would be an essential reading for students, researchers, and people from the food and pharma industry.

Bioprospects of Macrofungi: Recent Developments (Progress in Mycological Research)

by Sunil Kumar Deshmukh Kandikere R. Sridhar Hesham Ali El Enshasy

The discipline of mycology is a fascinating one. It has a major influence on the nutrition, health and environmental safety of mankind. Cultivation of edible and non-edible mushrooms for nutrition, pharmaceuticals, biopolymers and biocomposites will open up new avenues in research as well as the more profitable utilization of agricultural residues. Cultivation and of domesticated and wild mushrooms poses a challenge to fulfill the needs of human/animal nutrition and utilization of agrowastes tangibly. Cultivation of ectomycorrhizal fungi benefits nutrition as well as plant protection. Macrofungi are the major source of several metabolites of nutritional, health, agricultural and industrial significance (e.g., antioxidants, antimicrobials and pigments). Macrofungal bio composites provide alternatives to the use of animal-derived or plant-derived products (e.g., nanopapers, leather and packaging materials). They serve a dual role in providing nutrition and pharmaceuticals (nutraceuticals) to humans as well as livestock. Macrofungi interact with insects symbiotically (e.g., Termitomyces with termites) and provide delicious nutraceutical product. They also control insects by infecting and producing pharmaceutically and metabolite-rich products (e.g., Cordyceps attacks insects). Macrofungi have a strong potential to control pathogens like nematodes in soil (bioremediation). They are also useful as biofertilizers to meet the needs of plant nutrition. The book outlines current advances in macrofungal technology. It highlights different facets of macrofungal cultivation, bioactive compounds, biocomposites, nutraceuticals, benefits with interaction with insects, application as biofertilizers and ecosystem services like bioremediation.

Bioprospects of Macrofungi: Recent Developments (Progress in Mycological Research)

by Sunil Kumar Deshmukh Kandikere Ramaiah Sridhar Hesham Ali El Enshasy

The discipline of mycology is a fascinating one. It has a major influence on the nutrition, health and environmental safety of mankind. Cultivation of edible and non-edible mushrooms for nutrition, pharmaceuticals, biopolymers and biocomposites will open up new avenues in research as well as the more profitable utilization of agricultural residues. Cultivation and of domesticated and wild mushrooms poses a challenge to fulfill the needs of human/animal nutrition and utilization of agrowastes tangibly. Cultivation of ectomycorrhizal fungi benefits nutrition as well as plant protection. Macrofungi are the major source of several metabolites of nutritional, health, agricultural and industrial significance (e.g., antioxidants, antimicrobials and pigments). Macrofungal bio composites provide alternatives to the use of animal-derived or plant-derived products (e.g., nanopapers, leather and packaging materials). They serve a dual role in providing nutrition and pharmaceuticals (nutraceuticals) to humans as well as livestock. Macrofungi interact with insects symbiotically (e.g., Termitomyces with termites) and provide delicious nutraceutical product. They also control insects by infecting and producing pharmaceutically and metabolite-rich products (e.g., Cordyceps attacks insects). Macrofungi have a strong potential to control pathogens like nematodes in soil (bioremediation). They are also useful as biofertilizers to meet the needs of plant nutrition. The book outlines current advances in macrofungal technology. It highlights different facets of macrofungal cultivation, bioactive compounds, biocomposites, nutraceuticals, benefits with interaction with insects, application as biofertilizers and ecosystem services like bioremediation.

Bioprozesstechnik

by Horst Chmiel

Die "Weiße Biotechnologie" bringt den Durchbruch. Als "Weiße Biotechnologie" wird die biotechnische Massenproduktion von Bulk- und Feinchemikalien, Lebensmittelzusatzstoffen, Pharmaka, Biotreibstoffen etc. definiert, also gewissermaßen der Transfer der Ergebnisse aus dem Schüttelkolben in den industriellen Maßstab. Die Wahl der richtigen Prozesse und Parameter bei der Maßstabsübertragung entscheidet über die Wirtschaftlichkeit.Die 3., überarbeitete und aktualisierte Auflage dieses Fachbuchs bietet eine Einführung in die Grundlagen der Bioprozesstechnik und erläutert die wichtigsten Parameter und deren Verhalten bei der Maßstabsübertragung. Damit liegt es voll "im Trend", denn es hilft Studenten der Biotechnologie und Ingenieurwissenschaften die an sie im Studium, in der Forschung und der industriellen Praxis gestellten Aufgaben zu erfüllen.Das Werk beginnt mit einer Einführung in die Zellbiologie und Biochemie. Es folgen Beiträge zur Kinetik von Enzymen und Mikroorganismen. Weitere Kapitel beschäftigen sich mit den Fließeigenschaften von Biosuspensionen und deren Einfluss auf Transportvorgänge im Bioreaktor. Die Funktionsweise von Bioreaktoren und das Problem der Sterilität sowie die Mess- und Regeltechnik werden ausführlich behandelt. Mehr als die Hälfte der Kosten eines Bioprodukts entfallen auf die Aufarbeitung; ihr wird deshalb besondere Beachtung geschenkt. Das Werk endet mit einem Kapitel zu den verfahrenstechnischen Besonderheiten von höheren Eukaryoten und Enzymen.

Bioprozesstechnik

by Horst Chmiel Wolfgang Zettlmeier Ralf Takors Dirk Weuster-Botz

Dieses Werk wurde erstmals 1991 von Horst Chmiel herausgegeben und hat sich inzwischen als Standardwerk sowohl im Studium als auch in der Praxis der Biotechnologie etabliert. Die in weiten Teilen neue 4. Auflage des Lehrbuchs Bioprozesstechnik bietet eine umfassende Einführung zu allen Aspekten der modernen Bioprozesstechnik. Am Anfang stehen Beiträge zur Kinetik von Enzymen und Mikroorganismen, gefolgt von einem Kapitel zu Prozessmodellen. Weitere Beiträge beschäftigen sich mit den Fließeigenschaften von Biosuspensionen und deren Einfluss auf Transportvorgänge. Die Funktionsweise von Bioreaktoren und das Problem der Sterilität sowie die Mess- und Regeltechnik werden ausführlich behandelt. Oftmals entfallen mehr als die Hälfte der Kosten eines Bioprodukts auf die Aufarbeitung, ihr wird deshalb besondere Beachtung geschenkt. Der Beschreibung von ausgewählten Bioprozessen sind drei Kapitel gewidmet, bevor das Buch mit einem Beitrag zu systembiologischen Aspekten der Bioprozesstechnik abgeschlossen wird.

Bioreaction Engineering Principles: Second Edition

by Jens Nielsen John Villadsen Gunnar Lidén

This is the second edition of the text "Bioreaction Engineering Principles" by Jens Nielsen and John Villadsen, originally published in 1994 by Plenum Press (now part of Kluwer). Time runs fast in Biotechnology, and when Kluwer Plenum stopped reprinting the first edition and asked us to make a second, revised edition we happily accepted. A text on bioreactions written in the early 1990's will not reflect the enormous development of experimental as well as theoretical aspects of cellular reactions during the past decade. In the preface to the first edition we admitted to be newcomers in the field. One of us (JV) has had 10 more years of job training in biotechnology, and the younger author (IN) has now received international recognition for his work with the hottest topics of "modem" biotechnology. Furthermore we are happy to have induced Gunnar Liden, professor of chemical reaction engineering at our sister university in Lund, Sweden to join us as co-author of the second edition. His contribution, especially on the chemical engineering aspects of "real" bioreactors has been of the greatest value. Chapter 8 of the present edition is largely unchanged from the first edition. We wish to thank professor Martin Hjortso from LSU for his substantial help with this chapter.

Bioreaction Engineering Principles

by John Villadsen Jens Nielsen Gunnar Lidén

The present text is a complete revision of the 2nd edition from 2003 of the book with the same title. In recognition of the fast pace at which biotechnology is moving we have rewritten several chapters to include new scientific progress in the field from 2000 to 2010. More important we have changed the focus of the book to support its use, not only in universities, but also as a guide to design new processes and equipment in the bio-industry. A new chapter has been included on the prospects of the bio-refinery to replace many of the oil- and gas based processes for production of especially bulk chemicals. This chapter also serves to make students in Chemical Engineering and in the Bio-Sciences enthusiastic about the whole research field. As in previous editions we hope that the book can be used as textbook for classes, even at the undergraduate level, where chemical engineering students come to work side by side with students from biochemistry and microbiology. To help the chemical engineering students Chapter 1 includes a brief review of the most important parts of microbial metabolism. In our opinion this review is sufficient to understand microbial physiology at a sufficiently high level to profit from the rest of the book. Likewise the bio-students will not be overwhelmed by mathematics, but since the objective of the book is to teach quantitative process analysis and process design at a hands-on level some mathematics and model analysis is needed. We hope that the about 100 detailed examples and text notes, together with many instructive problems will be sufficient to illustrate how model analysis is used, also in Bio-reaction Engineering.

Bioreactor Engineering Research and Industrial Applications I: Cell Factories (Advances in Biochemical Engineering/Biotechnology #155)

by Qin Ye Jie Bao Jian-Jiang Zhong

This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

Bioreactor Engineering Research and Industrial Applications II (Advances in Biochemical Engineering/Biotechnology #152)

by Jie Bao Qin Ye Jian-Jiang Zhong

This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science.Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification.In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

Bioreactors for Microbial Biomass and Energy Conversion (Green Energy and Technology)

by Qiang Liao Jo-Shu Chang Christiane Herrmann Ao Xia

This book discusses recent trends and developments in the microbial conversion process, which serves as an important route for biofuel production, with particular attention to bioreactors. It combines microbial conversion with multiphase flow and mass transfer, providing an alternative perspective for the understanding of microbial biomass and energy production process as well as enhancement strategy. This book is relevant to students and researchers who work in the fields of renewable energy, engineering and biotechnology. Policymakers, economists and industry engineers also benefit from this book, as it can be used as a resource for the implementation of renewable energy technologies.

Bioreactors for Tissue Engineering: Principles, Design and Operation

by Julian Chaudhuri Mohamed Al-Rubeai

For the first time in a single volume, the design, characterisation and operation of the bioreactor system in which the tissue is grown is detailed. Bioreactors for Tissue Engineering presents an overall picture of the current state of knowledge in the engineering of bioreactors for several tissue types (bone, cartilage, vascular), addresses the issue of mechanical conditioning of the tissue, and describes the use of techniques such as MRI for monitoring tissue growth. This unique volume is dedicated to the fundamentals and application of bioreactor technology to tissue engineering products. Not only will it appeal to graduate students and experienced researchers in tissue engineering and regenerative medicine, but also to tissue engineers and culture technologists, academic and industrial chemical engineers, biochemical engineers and cell biologists who wish to understand the criteria used to design and develop novel systems for tissue growth in vitro.

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