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One Renegade Cell: How Cancer Begins (Science Masters Ser.)

by Robert A. Weinberg

Cancer research has reached a major turning point, and no one is better qualified to explain the past two deacades' dramatic leaps forward in understanding this disease than world-renowned molecular biologist Robert Weinberg, director of the Oncology Research Laboratory at the Whitehead Institute in Cambridge, Massachusetts. In One Renegade Cell, Weinberg presents a state-of-the-art account of how cancer begins and how, one day, it will be cured.

China: A History

by John Keay

An authoritative account of five thousand years of Chinese historyMany nations define themselves in terms of territory or people; China defines itself in terms of history. Taking into account the country's unrivaled, voluminous tradition of history writing, John Keay has composed a vital and illuminating overview of the nation's complex and vivid past. Keay's authoritative history examines 5,000 years in China, from the time of the Three Dynasties through Chairman Mao and the current economic transformation of the country. Crisp, judicious, and engaging, China is the classic single-volume history for anyone seeking to understand the present and future of this immensely powerful nation.

Physics in Mind: A Quantum View of the Brain

by Werner Loewenstein

No one can escape a sense of awe when reflecting on the workings of the mind: we see, we hear, we feel, we are aware of the world around us. But what is the mind? What do we mean when we say we are "aware” of something? What is this peculiar state in our heads, at once utterly familiar and bewilderingly mysterious, that we call awareness or consciousness?In Physics in Mind, eminent biophysicist Werner R. Loewenstein argues that to answer these questions, we must first understand the physical mechanisms that underlie the workings of the mind. And so begins an exhilarating journey along the sensory data stream of the brain, which shows how our most complex organ processes the vast amounts of information coming in through our senses to create a coherent, meaningful picture of the world. Bringing information theory to bear on recent advances in the neurosciences, Loewenstein reveals a web of immense computational power inside the brain. He introduces the revolutionary idea that quantum mechanics could be fundamental to how our minds almost instantaneously deal with staggering amounts of information, as in the case of the information streaming through our eyes.Combining cutting-edge research in neuroscience and physics, Loewenstein presents an ambitious hypothesis about the parallel processing of sensory information that is the heart, hub, and pivot of the cognitive brain. Wide-ranging and brimming with insight, Physics in Mind breaks new ground in our understanding of how the mind works.

Labor of Love, Labor of Sorrow: Black Women, Work, and the Family, from Slavery to the Present

by Jacqueline Jones

The forces that shaped the institution of slavery in the American South endured, albeit in altered form, long after slavery was abolished. Toiling in sweltering Virginia tobacco factories or in the kitchens of white families in Chicago, black women felt a stultifying combination of racial discrimination and sexual prejudice. And yet, in their efforts to sustain family ties, they shared a common purpose with wives and mothers of all classes.In Labor of Love, Labor of Sorrow, historian Jacqueline Jones offers a powerful account of the changing role of black women, lending a voice to an unsung struggle from the depths of slavery to the ongoing fight for civil rights.

Lucky Planet: Why Earth is Exceptional-and What That Means for Life in the Universe

by David Waltham

Why Earth’s life-friendly climate makes it exceptional-and what that means for the likelihood of finding intelligent extraterrestrial lifeWe have long fantasized about finding life on planets other than our own. Yet even as we become aware of the vast expanses beyond our solar system, it remains clear that Earth is exceptional. The question is: why? In Lucky Planet, astrobiologist David Waltham argues that Earth’s climate stability is what makes it uniquely able to support life, and it is nothing short of luck that made such conditions possible. The four billion year-stretch of good weather that our planet has experienced is statistically so unlikely that chances are slim that we will ever encounter intelligent extraterrestrial others. Citing the factors that typically control a planet’s average temperature-including the size of its moon, as well as the rate of the Universe’s expansion-Waltham challenges the prevailing scientific consensus that Earth-like planets have natural stabilizing mechanisms that allow life to flourish.A lively exploration of the stars above and the ground beneath our feet, Lucky Planet seamlessly weaves the story of Earth and the worlds orbiting other stars to give us a new perspective of the surprising role chance plays in our place in the universe.

The Big Ratchet: How Humanity Thrives in the Face of Natural Crisis

by Ruth DeFries

How an ordinary mammal manipulated nature to become technologically sophisticated city-dwellers--and why our history points to an optimistic future in the face of environmental crisisOur species long lived on the edge of starvation. Now we produce enough food for all 7 billion of us to eat nearly 3,000 calories every day. This is such an astonishing thing in the history of life as to verge on the miraculous. The Big Ratchet is the story of how it happened, of the ratchets--the technologies and innovations, big and small--that propelled our species from hunters and gatherers on the savannahs of Africa to shoppers in the aisles of the supermarket.The Big Ratchet itself came in the twentieth century, when a range of technologies--from fossil fuels to scientific plant breeding to nitrogen fertilizers--combined to nearly quadruple our population in a century, and to grow our food supply even faster. To some, these technologies are a sign of our greatness; to others, of our hubris. MacArthur fellow and Columbia University professor Ruth DeFries argues that the debate is the wrong one to have. Limits do exist, but every limit that has confronted us, we have surpassed. That cycle of crisis and growth is the story of our history; indeed, it is the essence of The Big Ratchet. Understanding it will reveal not just how we reached this point in our history, but how we might survive it.

Deadly Choices: How the Anti-Vaccine Movement Threatens Us All

by Paul A. Offit

Learn how we can prevent dangerous diseases -- and why some deadly epidemics are making a comeback -- in this guide to science, vaccines, and life-saving knowledge from a medical expert.In 2014, California suffered the largest and deadliest outbreak of pertussis, also known as "whooping cough," in more than fifty years.This tragedy was avoidable. An effective vaccine has been available since the 1940s. In recent years other diseases, like measles and mumps, have also made a comeback. The reason for these epidemics can be traced to a group whose vocal proponents insist, despite evidence to the contrary, that vaccines are poison. As a consequence, parents and caretakers are rejecting vaccines for themselves and their families.In Deadly Choices, infectious-disease expert Paul Offit takes a look behind the curtain of the anti-vaccine movement. What he finds is a reminder of the power of scientific knowledge, and the harm we risk if we ignore it.

The Epic of New York City: A Narrative History

by Edward Robb Ellis

In swift, witty chapters that flawlessly capture the pace and character of New York City, acclaimed diarist Edward Robb Ellis presents his masterpiece: a thorough, and thoroughly readable, history of America's largest metropolis. Ellis narrates some of the most significant events of the past three hundred years and more-the Revolutionary and Civil Wars, Alexander Hamilton and Aaron Burr's fatal duel, the formation of the League of Nations, the Great Depression-from the perspective of the city that experienced, and influenced, them all. Throughout, he infuses his account with the strange and delightful anecdotes that a less charming tour guide might omit, from the story of the city's first, block-long subway to that of the blizzard of 1888 that turned Macy's into one big slumber party. Playful yet authoritative, comprehensive yet intimate, The Epic of New York City confirms the words of its own epigraph, spoken by Oswald Spengler: "World history is city history," particularly when that city is the Big Apple.

Triangular Road: A Memoir

by Paule Marshall

In Triangular Road, famed novelist Paule Marshall tells the story of her years as a fledgling young writer in the 1960s. A memoir of self-discovery, it also offers an affectionate tribute to the inimitable Langston Hughes, who entered Marshall's life during a crucial phase and introduced her to the world of European letters during a whirlwind tour of the continent. In the course of her journeys to Europe, Barbados, and eventually Africa, Marshall comes to comprehend the historical enormity of the African diaspora, an understanding that fortifies her sense of purpose as a writer.In this unflinchingly honest memoir, Paule Marshall offers an indelible portrait of a young black woman coming of age as a novelist in a literary world dominated by white men.

America, Empire of Liberty: A New History of the United States

by David Reynolds

A magisterial history of the United States by a prize-winning historian"The best one-volume history of the United States ever written."--Joseph J. Ellis, author of Founding Brothers and The QuartetThomas Jefferson envisioned the United States as a great "empire of liberty." In his riveting single-volume history of the United States, award-winning historian David Reynolds takes Jefferson's phrase as a key to the American saga. He examines how the anti-empire of 1776 became the greatest superpower the world has seen--and how the country that offered liberty and opportunity on a scale unmatched in Europe nevertheless founded its prosperity on the labor of black slaves and the dispossession of Native Americans. Reynolds also reveals how these tensions between empire and liberty have often been resolved by faith--both the evangelical Protestantism that has energized US politics since the founding of the nation and the larger faith in American righteousness that has impelled the country's expansion. Written with verve, insight, and humor, America, Empire of Liberty is a magisterial depiction of America in all its grandeur and contradictions.

A Capitalism for the People: Recapturing the Lost Genius of American Prosperity

by Luigi Zingales

Born in Italy, University of Chicago economist Luigi Zingales witnessed firsthand the consequences of high inflation and unemployment-paired with rampant nepotism and cronyism-on a country's economy. This experience profoundly shaped his professional interests, and in 1988 he arrived in the United States, armed with a political passion and the belief that economists should not merely interpret the world, but should change it for the better.In A Capitalism for the People, Zingales makes a forceful, philosophical, and at times personal argument that the roots of American capitalism are dying, and that the result is a drift toward the more corrupt systems found throughout Europe and much of the rest of the world. American capitalism, according to Zingales, grew in a unique incubator that provided it with a distinct flavor of competitiveness, a meritocratic nature that fostered trust in markets and a faith in mobility. Lately, however, that trust has been eroded by a betrayal of our pro-business elites, whose lobbying has come to dictate the market rather than be subject to it, and this betrayal has taken place with the complicity of our intellectual class.Because of this trend, much of the country is questioning-often with great anger-whether the system that has for so long buoyed their hopes has now betrayed them once and for all. What we are left with is either anti-market pitchfork populism or pro-business technocratic insularity. Neither of these options presents a way to preserve what the author calls "the lighthouse” of American capitalism. Zingales argues that the way forward is pro-market populism, a fostering of truly free and open competition for the good of the people-not for the good of big business.Drawing on the historical record of American populism at the turn of the twentieth century, Zingales illustrates how our current circumstances aren't all that different. People in the middle and at the bottom are getting squeezed, while people at the top are only growing richer. The solutions now, as then, are reforms to economic policy that level the playing field. Reforms that may be anti-business (specifically anti-big business), but are squarely pro-market. The question is whether we can once again muster the courage to confront the powers that be.

Darwin Among The Machines: The Evolution Of Global Intelligence

by George B. Dyson

Darwin Among the Machines tells the story of humankind&’s journey into the digital wilderness. Introducing a cast of familiar and not-so-familiar characters, historian of science George B. Dyson traces the course of the information revolution, illuminating the lives and work of visionaries—from Thomas Hobbes to John von Neumann—who foresaw the development of artificial intelligence, artificial life, and artificial mind. This profound and elegant book derives both its title and its outlook from Samuel Butler&’s 1863 essay, &“Darwin Among the Machines.&” Observing the beginnings of miniaturization, self-reproduction, and telecommunication among machines, Butler predicted that nature&’s intelligence, only temporarily subservient to technology, would resurface to claim our creations as her own. Updating Butler&’s arguments, Dyson distills the historical record to chronicle the origins of digital telecommunications and the evolution of digital computers, beginning long before the time of Darwin and exploring the limits of Darwinian evolution to suggest what lies beyond. Weaving a cohesive narrative of his brilliant predecessors, Dyson constructs a straightforward, convincing, and occasionally frightening view of the evolution of mind in the global network, on a level transcending our own. Dyson concludes that we are in the midst of an experiment that echoes the prehistory of human intelligence and the origins of life. Just as the exchange of coded molecular instructions brought life as we know it to the early earth&’s primordial soup, and as language and mind combined to form the culture in which we live, so, in the digital universe, are computer programs and worldwide networks combining to produce an evolutionary theater in which the distinctions between nature and technology are increasingly obscured. Nature, argues Dyson, is on the side of the machines.

The Best Business Books Ever: The Most Influential Management Books You'll Never Have Time To Read

by Basic Books

Every manager could benefit from a solid grounding in the history and evolution of business thinking. The Best Business Books Ever is a uniquely organized guide and an illuminating collection of key ideas from the 130 most influential business books of all time. It places both historical and contemporary works in context and draws fascinating parallels and points of connection. Now fully revised and more than 30 percent bigger, this one book highlights the information you need to know and why it's important to know it, and does it all in a succinct, time-saving fashion. Business moves faster than ever these days. For the businessperson who has a growing list of tomes that they can never quite seem to get to, The Best Business Books Ever is a must-have.

Sex, Murder, and the Meaning of Life: A Psychologist Investigates How Evolution, Cognition, and Complexity are Revolutionizing our View of Human Nature

by Douglas T. Kenrick

&“Kenrick writes like a dream.&”—Robert Sapolsky, Professor of Biology and Neurology, Stanford University; author of A Primate&’s Memoir and Why Zebras Don&’t Get Ulcers What do sex and murder have to do with the meaning of life? Everything.In Sex, Murder, and the Meaning of Life, social psychologist Douglas Kenrick exposes the selfish animalistic underside of human nature, and shows how it is intimately connected to our greatest and most selfless achievements. Masterfully integrating cognitive science, evolutionary psychology, and complexity theory, this intriguing book paints a comprehensive picture of the principles that govern our lives. As Kenrick divulges, beneath our civilized veneer, human beings are a lot like howling hyenas and barking baboons, with heads full of homicidal tendencies and sexual fantasies. But, in his view, many ingrained, apparently irrational behaviors—such as inclinations to one-night stands, racial prejudices, and conspicuous consumption—ultimately manifest what he calls &“Deep Rationality.&”Although our heads are full of simple selfish biases that evolved to help our ancestors survive, modern human beings are anything but simple and selfish cavemen. Kenrick argues that simple and selfish mental mechanisms we inherited from our ancestors ultimately give rise to the multifaceted social lives that we humans lead today, and to the most positive features of humanity, including generosity, artistic creativity, love, and familial bonds. And out of those simple mechanisms emerge all the complexities of society, including international conflicts and global economic markets. By exploring the nuance of social psychology and the surprising results of his own research, Kenrick offers a detailed picture of what makes us caring, creative, and complex—that is, fully human. Illuminated with stories from Kenrick&’s own colorful experiences -- from his criminally inclined shantytown Irish relatives, his own multiple high school expulsions, broken marriages, and homicidal fantasies, to his eventual success as an evolutionary psychologist and loving father of two boys separated by 26 years -- this book is an exploration of our mental biases and failures, and our mind&’s great successes. Idiosyncratic, controversial, and fascinating, Sex, Murder, and the Meaning of Life uncovers the pitfalls and promise of our biological inheritance.

Mad in America: Bad Science, Bad Medicine, and the Enduring Mistreatment of the Mentally Ill

by Robert Whitaker

Schizophrenics in the United States currently fare worse than patients in the world's poorest countries. In Mad in America, medical journalist Robert Whitaker argues that modern treatments for the severely mentally ill are just old medicine in new bottles, and that we as a society are deeply deluded about their efficacy. The widespread use of lobotomies in the 1920s and 1930s gave way in the 1950s to electroshock and a wave of new drugs. In what is perhaps Whitaker's most damning revelation, Mad in America examines how drug companies in the 1980s and 1990s skewed their studies to prove that new antipsychotic drugs were more effective than the old, while keeping patients in the dark about dangerous side effects.A haunting, deeply compassionate book-now revised with a new introduction-Mad in America raises important questions about our obligations to the mad, the meaning of "insanity,” and what we value most about the human mind.

Talking to Terrorists: Why America Must Engage with its Enemies

by Mark Perry

It has long been an article of faith that the United States does not "talk to terrorists”-that to engage in dialogue with groups such as Hamas, Hezbollah, and the Muslim Brotherhood would be tacitly to acknowledge their status as legitimate political actors. Not so, argues Middle East expert Mark Perry. In the absence of dialogue, we have lumped these groups together with Al Qaeda as part of a monolithic enemy defined by a visceral hatred of American values. In reality, while they hold deep grievances about specific US policies, they are ultimately far more defined by their opposition to the deliberately anti-political Salafist ideology of Al Qaeda.Drawing on extensive interviews with Washington insiders, Perry describes fruitful covert meetings between members of the US armed forces and leaders of the Iraqi insurgency to demonstrate that talking to terrorists may be best way to end terrorism-controversial wisdom we ignore at our peril.

Cain's Legacy: Liberating Siblings from a Lifetime of Rage, Shame, Secrecy, and Regret

by Jeanne Safer

Bonds between brothers and sisters are among the longest lasting and most emotionally significant of human relationships. But while 45 percent of adults struggle with serious sibling strife, few discuss it openly. Even fewer resolve it to their satisfaction. In Cain&’s Legacy, psychotherapist Jeanne Safer, a recognized authority on sibling psychology (and an estranged sister herself) illuminates this pervasive but hidden phenomenon. She explores the roots of inter-sibling woes, from siblicide in the book of Genesis to tensions in Freud&’s family history. Drawing on sixty in-depth interviews with adult siblings struggling with conflicts over money, family businesses, aging parents, contentious wills, unhealed childhood wounds, and blocked communication, Safer provides compassionate guidance to brothers and sisters whose relationship is broken. She helps siblings overcome their paralysis and pain, revealing how they can come to terms with the one peer relationship they can never sever—even if they never see each other again. A heartfelt look at a too-often avoided topic, Cain&’s Legacy is a sympathetic and clear-eyed guide to navigating the darkness separating us from our brothers and sisters.

Flying High: Remembering Barry Goldwater

by William F. Buckley Jr.

In Flying High, William F. Buckley Jr. offers his lyrical remembrance of a singular era in American politics, and a tribute to the modern Conservative movement's first presidential standard-bearer, Barry Goldwater. Goldwater was in many ways the perfect candidate: self-reliant, unpretentious, unshakably honest, and dashingly handsome. And although he lost the election, he electrified millions of voters with his integrity and a sense of decency-qualities that made him a natural spokesman for Conservative ideals and an inspiration for decades to come.In an era when Republicans are looking for a leader, Flying High is a reminder of how real political visionaries inspire devotion.

The Future of Nostalgia

by Svetlana Boym

Combining personal memoir, philosophical essay, and historical analysis, Svetlana Boym explores the spaces of collective nostalgia that connect national biography and personal self-fashioning in the twenty-first century. She guides us through the ruins and construction sites of post-communist cities--St. Petersburg, Moscow, Berlin, and Prague--and the imagined homelands of exiles-Benjamin, Nabokov, Mandelstahm, and Brodsky. From Jurassic Park to the Totalitarian Sculpture Garden, Boym unravels the threads of this global epidemic of longing and its antidotes.

How to Create the Perfect Wife: Britain's Most Ineligible Bachelor and his Enlightened Quest to Train the Ideal Mate

by Wendy Moore

A captivating tale of one man's mission to groom his ideal mate.Thomas Day, an 18th-century British writer and radical, knew exactly the sort of woman he wanted to marry. Pure and virginal, yet tough and hardy, and completely subervient to his whims. But after being rejected by a number of spirited young women, Day concluded that the perfect partner he envisioned simply did not exist in frivolous, fashion-obsessed Georgian society. Rather than conceding defeat and giving up on his search for the woman of his dreams, however, Day set out to create her.So begins the extraordinary true story at the heart of How to Create the Perfect Wife. A few days after he turned twenty-one and inherited a large fortune, Day adopted two young orphans from the Founding Hospital and, guided by the writings of Jean-Jacques Rousseau and the principles of the Enlightenment, attempted to teach them to be model wives.Day's peculiar experiment inevitably backfired -- though not before he had taken his theories about marriage, education, and femininity to shocking extremes.Stranger than fiction, blending tragedy and farce, How to Create the Perfect Wife is an engrossing tale of the radicalism -- and deep contradictions -- at the heart of the enlightenment.

The Assassin's Accomplice: Mary Surratt and the Plot to Kill Abraham Lincoln

by Kate Clifford Larson

In The Assassin's Accomplice, historian Kate Clifford Larson tells the gripping story of Mary Surratt, a little-known participant in the plot to kill Abraham Lincoln, and the first woman ever to be executed by the federal government of the United States. Surratt, a Confederate sympathizer, ran the boarding house in Washington where the conspirators-including her rebel son, John Surratt-met to plan the assassination. When a military tribunal convicted her for her crimes and sentenced her to death, five of the nine commissioners petitioned President Andrew Johnson to show mercy on Surratt because of her sex and age. Unmoved, Johnson refused-Surratt, he said, "kept the nest that hatched the egg.” Set against the backdrop of the Civil War, The Assassin's Accomplice tells the intricate story of the Lincoln conspiracy through the eyes of its only female participant. Based on long-lost interviews, confessions, and court testimony, the text explores how Mary's actions defied nineteenth-century norms of femininity, piety, and motherhood, leaving her vulnerable to deadly punishment historically reserved for men. A riveting narrative account of sex, espionage, and murder cloaked in the enchantments of Southern womanhood, The Assassin's Accomplice offers a fresh perspective on America's most famous murder.

Song of Wrath: The Peloponnesian War Begins

by J. E. Lendon

Song of Wrath tells the story of Classical Athens' victorious Ten Years' War (431- 421 BC) against grim Sparta-the first decade of the terrible Peloponnesian War that turned the Golden Age of Greece to lead. Historian J.E. Lendon presents a sweeping tale of pitched battles by land and sea, sieges, sacks, raids, and deeds of cruelty and guile-along with courageous acts of mercy, surprising charity, austere restraint, and arrogant resistance. Recounting the rise of democratic Athens to great-power status, and the resulting fury of authoritarian Sparta, Greece's traditional leader, Lendon portrays the causes and strategy of the war as a duel over national honor, a series of acts of revenge. A story of new pride challenging old, Song of Wrath is the first work of Ancient Greek history for the post-cold-war generation.

Born to Use Mics: Reading Nas's Illmatic

by Michael Eric Dyson Sohail Daulatzai

At the age of nineteen, Nasir "Nas” Jones began recording tracks for his debut album-and changed the music world forever. Released in 1994, Illmatic was hailed as an instant masterpiece and has proven one of the most influential albums in hip-hop history. With its close attention to beats and lyricism, and riveting first-person explorations of the isolation and desolation of urban poverty, Illmatic was pivotal in the evolution of the genre.In Born to Use Mics, Michael Eric Dyson and Sohail Daulatzai have brought together renowned writers and critics including Mark Anthony Neal, Marc Lamont Hill, Eddie S. Glaude, Jr., and many others to confront Illmatic song by song, with each scholar assessing an individual track from the album. The result is a brilliant engagement with and commentary upon one of the most incisive sets of songs ever laid down on wax.

A Wicked Company: The Forgotten Radicalism of the European Enlightenment

by Philipp Blom

The flourishing of radical philosophy in Baron Thierry Holbach's Paris salon from the 1750s to the 1770s stands as a seminal event in Western history. Holbach's house was an international epicenter of revolutionary ideas and intellectual daring, bringing together such original minds as Denis Diderot, Laurence Sterne, David Hume, Adam Smith, Ferdinando Galiani, Horace Walpole, Benjamin Franklin, Guillaume Raynal, and Jean-Jacques Rousseau.In A Wicked Company, acclaimed historian Philipp Blom retraces the fortunes of this exceptional group of friends. All brilliant minds, full of wit, courage, and insight, their thinking created a different and radical French Enlightenment based on atheism, passion, reason, and truly humanist thinking. A startlingly relevant work of narrative history, A Wicked Company forces us to confront with new eyes the foundational debates about modern society and its future.

Massive: The Missing Particle That Sparked the Greatest Hunt in Science

by Ian Sample

The biggest science story of our time, Massive spans four decades, weaving together the personal narratives and international rivalries behind the search for the "God" particle, or Higgs boson. A story of grand ambition, intense competition, clashing egos, and occasionally spectacular failures, Massive is the first book that reveals the science, culture, and politics behind the biggest unanswered question in modern physics-what gives things mass? Drawing upon his unprecedented access to Peter Higgs, after whom the particle is named, award-winning science writer Ian Sample chronicles the multinational and multibillion-dollar quest to solve the mystery of mass. For scientists, to find the God particle is to finally understand the origin of mass, and until now, the story of their search has never been told.

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