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Oxadiazole in Material and Medicinal Chemistry

by Satish Kumar Priya Ranjan Sahoo Abhishek Saxena

The book “Oxadiazole in Material and Medicinal Chemistry” is based on the utility of organic motifs that contain oxadiazole units in their molecular architecture. Most of the common and alternate ways to synthesize oxadiazole-based probes have been discussed. The book also features some of the advanced applications of such organic motifs in liquid crystals, OLEDs, imaging agents, and medicines. Few practical applications of oxadiazole-based molecules in material and electronic areas have also been outlined. The book focuses on understanding the role of oxadiazole scaffolds in biological events, disease monitoring, and detection. The therapeutic effect of oxadiazole-based probes on cancer, inflammation, and neurodegeneration have also been covered in the book. Oxadiazole probes in inhibitor design and the corresponding inhibitory potency as drug development have been outlined. The authors hope that the book will garner positive interest among students and researchers associated with material and medicinal chemistry.

Oxadiazole in Material and Medicinal Chemistry

by Satish Kumar Priya Ranjan Sahoo Abhishek Saxena

The book “Oxadiazole in Material and Medicinal Chemistry” is based on the utility of organic motifs that contain oxadiazole units in their molecular architecture. Most of the common and alternate ways to synthesize oxadiazole-based probes have been discussed. The book also features some of the advanced applications of such organic motifs in liquid crystals, OLEDs, imaging agents, and medicines. Few practical applications of oxadiazole-based molecules in material and electronic areas have also been outlined. The book focuses on understanding the role of oxadiazole scaffolds in biological events, disease monitoring, and detection. The therapeutic effect of oxadiazole-based probes on cancer, inflammation, and neurodegeneration have also been covered in the book. Oxadiazole probes in inhibitor design and the corresponding inhibitory potency as drug development have been outlined. The authors hope that the book will garner positive interest among students and researchers associated with material and medicinal chemistry.

Oxford A-z Of Grammar And Punctuation: (pdf)

by John Seely

The Oxford A-Z of Grammar and Punctuation offers accessible and coherent explanations across a broad range of topics, and is an excellent first port of call for any reader seeking clear, authoritative help with grammar and punctuation. Incorporating hundreds of examples of real usage taken from the Oxford English Corpus, this handy volume contains more than 300 alphabetically-arranged entries, including standard grammatical terms such as active voice, conjunction, pronoun, synonym, and transitive verb. It also discusses related questions of usage, including how to distinguish between 'may or might', 'that or which', and 'it's or its'. Over 30 feature entries on major headwords like adverb, clause, and spelling include diagrams listing related terms. The A-Z has been fully revised and updated, and the structure and approach has been revisited to improve its accessibility, including clearer typographical conventions, and the reintroduction of the easy-to-use two-colour format found in early editions. Major headwords have been made (where possible) shorter and easier to navigate, and all sample sentences have been revised, replacing those that are out of date and adding new ones where needed. Readers of all levels will find this volume to be an essential tool for writing at home, in the office, at school, and at college.

The Oxford Compendium of Visual Illusions

by Arthur Shapiro and Dejan Todorović

Visual illusions cut across academic divides and popular interests: on the one hand, illusions provide entertainment as curious tricks of the eye; on the other hand, scientific research related to illusory phenomena has given generations of scientists and artists deep insights into the brain and principles of mind and consciousness. Numerous thinkers (including Aristotle, Descartes, Da Vinci, Escher, Goethe, Galileo, Helmholtz, Maxwell, Newton, and Wittgenstein) have been lured by the apparent simplicity of illusions and the promise that illusory phenomena can elucidate the puzzling relationship between the physical world and our perceptual reality. Over the past thirty years, advances in imaging and electrophysiology has dramatically expanded the range of illusions and enabled new forms of analysis, thereby creating new and exciting ways to consider how the brain constructs our perceptual world. The Oxford Compendium of Visual Illusions is a collection of over one hundred chapters about illusions, displayed and discussed by the researchers who invented and conducted research on the illusions. Chapters include full-color images, associated videos, and extensive references. The book is divided into eleven sections: first, a presentation of general history and viewpoints on illusions, followed by sections on geometric, color, motion, space, faces, and cross-category illusions. The book will be of interest to vision scientists, neuroscientists, psychologists, physicists, philosophers, artists, designers, advertisers, and educators curious about applied aspects of visual perception and the brain.

The Oxford Handbook of American Election Law (Oxford Handbooks)

by Eugene D. Mazo

The Oxford Handbook of American Election Law offers a sophisticated introduction to one of the most dynamic, contested, and consequential areas of American law. Election law plays a critical role in regulating the political arena at a time when most Americans are witnessing unprecedented levels of polarization. The field is rife with controversies, yet understanding it is also vital to the success of American democracy. The Handbook provides a comprehensive overview of American election law, a survey of the core themes that encompass the field, and summaries of its most pressing debates. This book is the first of its kind, bringing together 47 leading scholars of American election law to offer definitive perspectives on their field. The book begins by explaining how election law relates to several of its closest academic cousins, including constitutional law, democratic theory, and empirical social science. It then goes on to explore the major topics in election law, including the right to vote, the rules of running for office, the role of political parties, the dynamics of redistricting and gerrymandering, the history and necessity of the Voting Rights Act, the intricacies of campaign finance, and the recurring controversies surrounding election administration in the individual states. Election law warrants careful, detailed, and thorough analysis. The Oxford Handbook of American Election Law offers readers a clearly written guide to aid navigation through this thorny terrain, crystallizing controversial issues and situating them within the field's ongoing scholarly debates. The book aims to reach newcomers to the field as well as those who hope to gain a firmer understanding of election law's nuances, intricacies, and complexities. Unparalleled in the breadth and depth of its coverage, The Oxford Handbook of American Election Law is an invaluable resource for scholars, students, policymakers, and practitioners.

The Oxford Handbook of American Election Law (Oxford Handbooks)


The Oxford Handbook of American Election Law offers a sophisticated introduction to one of the most dynamic, contested, and consequential areas of American law. Election law plays a critical role in regulating the political arena at a time when most Americans are witnessing unprecedented levels of polarization. The field is rife with controversies, yet understanding it is also vital to the success of American democracy. The Handbook provides a comprehensive overview of American election law, a survey of the core themes that encompass the field, and summaries of its most pressing debates. This book is the first of its kind, bringing together 47 leading scholars of American election law to offer definitive perspectives on their field. The book begins by explaining how election law relates to several of its closest academic cousins, including constitutional law, democratic theory, and empirical social science. It then goes on to explore the major topics in election law, including the right to vote, the rules of running for office, the role of political parties, the dynamics of redistricting and gerrymandering, the history and necessity of the Voting Rights Act, the intricacies of campaign finance, and the recurring controversies surrounding election administration in the individual states. Election law warrants careful, detailed, and thorough analysis. The Oxford Handbook of American Election Law offers readers a clearly written guide to aid navigation through this thorny terrain, crystallizing controversial issues and situating them within the field's ongoing scholarly debates. The book aims to reach newcomers to the field as well as those who hope to gain a firmer understanding of election law's nuances, intricacies, and complexities. Unparalleled in the breadth and depth of its coverage, The Oxford Handbook of American Election Law is an invaluable resource for scholars, students, policymakers, and practitioners.

Oxford Handbook of Developmental Cognitive Neuroscience (Oxford Library of Psychology)

by Kathrin Cohen Kadosh

The Oxford Handbook of Developmental Cognitive Neuroscience brings together the leading developmental cognitive neuroscientists in the field that work on understanding human development, and the complex interplay of genetic, environmental, and brain maturational factors that shape social and cognitive functioning in development. It includes chapters on new, emerging research areas that show promise for understanding both brain and behaviour in development, such as nutrition and the microbiome gut-brain axis and sleep. Looking beyond early developmental changes, this handbook also places importance on the period of adolescence, which is an important developmental juncture. By assuming complexity from the outset, the developmental cognitive neuroscience research approach provides much needed insights into both the initial set-up of brain networks and cognitive mechanisms, and also into adaptability across the developmental trajectory. This is important not only for scientists studying typical and atypical development, but also for interventional work looking for critical or sensitive periods where interventions would be most effective. The developmental cognitive neuroscience research approach intersects nature and nurture and considers both health and disease models. It also focuses on understanding the complexity of human development, necessitating a multi-level and multi-factor research approach to grasp change and plasticity which, by definition, is multidisciplinary. The Oxford Handbook of Developmental Cognitive Neuroscience is a landmark volume, providing the reader with a comprehensive and state-of-the-art overview of current research in the field, whilst highlighting current gaps and directions for future research.

The Oxford Handbook of Digital Religion (Oxford Handbooks)

by Heidi A. Campbell and Pauline Hope Cheong

The recently-coined term digital religion refers to the understanding that contemporary religion is practiced in both online and offline contexts, and these contexts intersect with one another. Scholars of digital religion recognize that religion is increasingly influenced and informed by its interactions with computer-mediated, digital technologies, including not only the different manifestations of the internet, but other emerging forms of technology, such as mobile phones and video games. The Oxford Handbook of Digital Religion will provide a comprehensive overview of religion as seen and performed through these various media, platforms, and cultural spaces. The text will cover religious engagement with a wide range of digital media forms (including social media, websites, gaming environments, virtual and augmented realities, etc.) and highlight examples of technological engagement and negotiation within the major world religions (i.e. Buddhism, Christianity, Hinduism, Islam, and Judaism), as well as significant subgroups. And because of the interdisciplinary nature of the field, the Handbook will be led by co-editors representing the fields of religious studies and communications, both with experience in how those disciplines intersect.

The Oxford Handbook of Digital Religion (Oxford Handbooks)


The recently-coined term digital religion refers to the understanding that contemporary religion is practiced in both online and offline contexts, and these contexts intersect with one another. Scholars of digital religion recognize that religion is increasingly influenced and informed by its interactions with computer-mediated, digital technologies, including not only the different manifestations of the internet, but other emerging forms of technology, such as mobile phones and video games. The Oxford Handbook of Digital Religion will provide a comprehensive overview of religion as seen and performed through these various media, platforms, and cultural spaces. The text will cover religious engagement with a wide range of digital media forms (including social media, websites, gaming environments, virtual and augmented realities, etc.) and highlight examples of technological engagement and negotiation within the major world religions (i.e. Buddhism, Christianity, Hinduism, Islam, and Judaism), as well as significant subgroups. And because of the interdisciplinary nature of the field, the Handbook will be led by co-editors representing the fields of religious studies and communications, both with experience in how those disciplines intersect.

The Oxford Handbook of Health Psychology (Oxford Library of Psychology)

by Howard S. Friedman

The flaws in today's healthcare systems and practices are well-documented: millions remain far from optimal health due to a variety of psychological and social factors; large numbers of patients do not fully cooperate with medical advice; errors in medical decision-making -- some stemming from flaws in interpersonal relations -- regularly lead to needless suffering and death. Further, the effects of emotions, personality, and motivation on healing are not well incorporated into traditional medical care. The Oxford Handbook of Health Psychology compiles the most relevant scholarship from psychology, medicine, and public health to offer a thorough and authoritative model of the biopsychosocial approach to health. A collection of international contributors addresses all relevant concepts in this model, including its applications to health promotion, health behavior change, and treatment.

The Oxford Handbook of Islamic Archaeology (Oxford Handbooks)

by Timothy Insoll Corisande Fenwick Bethany Walker

Born from the fields of Islamic art and architectural history, the archaeological study of the Islamic societies is a relatively young discipline. With its roots in the colonial periods of the late 19th and early 20th centuries, its rapid development since the 1980s warrants a reevaluation of where the field stands today. This Handbook represents for the first time a survey of Islamic archaeology on a global scale, describing its disciplinary development and offering candid critiques of the state of the field today in the Central Islamic Lands, the Islamic West, Sub-Saharan Africa, and Asia. The international contributors to the volume address such themes as the timing and process of Islamization, the problems of periodization and regionalism in material culture, cities and countryside, cultural hybridity, cultural and religious diversity, natural resource management, international trade in the later historical periods, and migration. Critical assessments of the ways in which archaeologists today engage with Islamic cultural heritage and local communities closes the volume, highlighting the ethical issues related to studying living cultures and religions. Richly illustrated, with extensive citations, it is the reference work on the debates that drive the field today.

The Oxford Handbook of Media and Social Justice (Oxford Library of Psychology)

by Srividya Ramasubramanian and Omotayo O. Banjo

The urgency and complexity of contemporary social justice issues facing the world today mean that activists, scholars, and storytellers need a readily available compendium of cutting-edge scholarship on media and social justice. The Oxford Handbook of Media and Social Justice gathers over forty leading scholars and presents a state-of-the-art systematic overview of media and social justice. Representing leading voices across positionalities and perspectives, geographies and generations, meta-theories and methods, and issues and identities, the Handbook explores intersecting identities, social structures, and power networks within media ownership, representation, selection, uses, effects, networks, and social transformation. These theories, methods, and practices expose media and digital divides, polarization, marginalization, exclusion, alienation, invisibilities, stigma, and trivializations. Yet, they also showcase how individuals and communities also have agency through refusal and resistance. Each of the 32 chapters includes a brief history, key concepts, contemporary debates and dialogues, and future directions, and the volume concludes with reflections on resistances, reckoning, and reparative justice. Connecting critical media scholarship with intersectional feminism, postcolonial/anticolonial theory, Indigenous approaches, queer theory, diaspora studies, and environmental justice frameworks, the Handbook re-envisions the role of media and technology with an inclusive trauma-informed approach to scholarship that is essential for the future of this research.

The Oxford Handbook of Media and Social Justice (Oxford Library of Psychology)


The urgency and complexity of contemporary social justice issues facing the world today mean that activists, scholars, and storytellers need a readily available compendium of cutting-edge scholarship on media and social justice. The Oxford Handbook of Media and Social Justice gathers over forty leading scholars and presents a state-of-the-art systematic overview of media and social justice. Representing leading voices across positionalities and perspectives, geographies and generations, meta-theories and methods, and issues and identities, the Handbook explores intersecting identities, social structures, and power networks within media ownership, representation, selection, uses, effects, networks, and social transformation. These theories, methods, and practices expose media and digital divides, polarization, marginalization, exclusion, alienation, invisibilities, stigma, and trivializations. Yet, they also showcase how individuals and communities also have agency through refusal and resistance. Each of the 32 chapters includes a brief history, key concepts, contemporary debates and dialogues, and future directions, and the volume concludes with reflections on resistances, reckoning, and reparative justice. Connecting critical media scholarship with intersectional feminism, postcolonial/anticolonial theory, Indigenous approaches, queer theory, diaspora studies, and environmental justice frameworks, the Handbook re-envisions the role of media and technology with an inclusive trauma-informed approach to scholarship that is essential for the future of this research.

The Oxford Handbook of Modern French Philosophy (Oxford Handbooks)

by Mark Sinclair Daniel Whistler

French philosophy is an internationally celebrated national philosophical tradition, and this Oxford Handbook offers a comprehensive approach to its history since 1800. The Handbook features essays written by renowned international specialists, illuminating key movements and positions, themes and thinkers in nineteenth-, twentieth- and even twenty-first-century French philosophy. The volume takes into account developments in recent historical scholarship by broadening the notion of Modern French Philosophy in two ways. Whereas recent approaches in the field have often ignored early nineteenth-century developments, this volume offers comprehensive treatment of French thought of this period in order to grasp better later developments. Moreover, the volume extends the canon at the other end of the period of Modern French Philosophy by including work on philosophers who have come to prominence only in the last ten or twenty years. The volume takes 'French philosophy' in a broad sense to include all philosophy carried out in France over the last 200 years, and it illuminates the institutional and cultural background of this national philosophical tradition in such a way as to provide a fuller and more comprehensive understanding of its unity and of its more famous moments in the twentieth century.

The Oxford Handbook of Monsters in Classical Myth (Oxford Handbooks)


The Oxford Handbook of Monsters in Classical Myth presents forty chapters about the unique and terrifying creatures from myths of the long-ago Near East and Mediterranean world, featuring authoritative contributions by many of the top international experts on ancient monsters and the monstrous. The first part provides original studies of individual monsters such as the Chimaera, Cerberus, the Hydra, and the Minotaur, and of monster groups such as dragons, centaurs, sirens, and Cyclopes. This section also explores their encounters with the major heroes of classical myth, including Perseus, Jason, Heracles, and Odysseus. The second part examines monsters of ancient folklore and ethnography, encompassing the restless dead, blood-drinking lamiae, exotic hybrid animals, the so-called dog-headed men, and many other unexpected creatures and peoples. The third part covers various interpretations of these creatures from multiple perspectives, including psychoanalysis, colonialism, and disability studies, with monster theory itself evident across the entire volume. The final part discusses reception of these ancient monsters across time and space--from the Middle Ages to the Renaissance to modern times, from Persia to Scandinavia, the Caribbean, and Latin America-and concludes with chapters considering the use and adaptation of ancient monsters in children's literature, science fiction, fantasy, and modern scientific disciplines. This Handbook is the first large-scale, inclusive guide to monsters in antiquity, their places in literature and art across the millennia, and their influence on later literature and thought.

The Oxford Handbook of Sociology for Social Justice (Oxford Handbooks)

by Corey Dolgon

The Oxford Handbook of Sociology for Social Justice calls on sociologists to be first and foremost activists who apply sociological skills and imaginations to the work of organizing, mobilizing, educating, and envisioning radical social change. There has never been a more important time for such work. As millions of people are organizing and mobilizing in new and unparalleled ways to challenge the global powers responsible for political repression, exploitation and poverty, social devastation and ecological destruction, authoritarian movements are growing just as rapidly. This transformative political and social moment calls for the boldest forms of praxis from radical scholar-activists. This Handbook includes theoretical framing pieces on the decolonization of sociology and its demand for an alternative approach to social science developing from grassroots engagements to challenge powers of exploitation and oppression. This collection also provides critical case studies on sociological work committed to progressive policy initiatives and a variety of local and global organizing efforts from the classroom to industrial labor unions, from farmers and farm workers to musicians and journalists, and other public intellectual efforts. It has been written and edited in a way that might inspire students and faculty not to abandon the passion for political change and social justice that may have brought them to sociology in the first place. The contributors to this volume come from around the world and are finding ways to link their skills and interests to struggles for justice and liberation in powerful and creative ways. The possibilities are limited only by the collective imagination of groups' and movements' capacities to develop solidarity and find meaning and joy in struggle. Scholars are trained to look for new knowledge in the physical and virtual stacks of libraries where philosophers have tried to interpret the world. The Oxford Handbook of Sociology for Social Justice is an attempt to inspire sociologists to look and engage elsewhere if we hope to change it.

The Oxford Handbook of Sociology for Social Justice (Oxford Handbooks)


The Oxford Handbook of Sociology for Social Justice calls on sociologists to be first and foremost activists who apply sociological skills and imaginations to the work of organizing, mobilizing, educating, and envisioning radical social change. There has never been a more important time for such work. As millions of people are organizing and mobilizing in new and unparalleled ways to challenge the global powers responsible for political repression, exploitation and poverty, social devastation and ecological destruction, authoritarian movements are growing just as rapidly. This transformative political and social moment calls for the boldest forms of praxis from radical scholar-activists. This Handbook includes theoretical framing pieces on the decolonization of sociology and its demand for an alternative approach to social science developing from grassroots engagements to challenge powers of exploitation and oppression. This collection also provides critical case studies on sociological work committed to progressive policy initiatives and a variety of local and global organizing efforts from the classroom to industrial labor unions, from farmers and farm workers to musicians and journalists, and other public intellectual efforts. It has been written and edited in a way that might inspire students and faculty not to abandon the passion for political change and social justice that may have brought them to sociology in the first place. The contributors to this volume come from around the world and are finding ways to link their skills and interests to struggles for justice and liberation in powerful and creative ways. The possibilities are limited only by the collective imagination of groups' and movements' capacities to develop solidarity and find meaning and joy in struggle. Scholars are trained to look for new knowledge in the physical and virtual stacks of libraries where philosophers have tried to interpret the world. The Oxford Handbook of Sociology for Social Justice is an attempt to inspire sociologists to look and engage elsewhere if we hope to change it.

The Oxford Handbook of the Malawi Economy (Oxford Handbooks)

by Hopestone Kayiska Chavula, Harold P. E. Ngalawa, Boniface Dulani and Thomas Chataghalala Munthali

The Oxford Handbook of the Malawi Economy is an essential reference material with new research contributions and insights across the different areas of economic development to shape the country's future growth and development trajectory. The volume is the first publication that tries to assess the performance of the Malawi economy since independence, by examining how the underpinning political and economic history, and the associated policies and strategies have affected the country's long-term socio-economic development. It captures a broad range of opinions, approaches, and conclusions, which serve to underline both the complexity of the issues and challenges facing Malawi, and the immense difficulties in tackling them. Common themes emerge as many authors agree that the country needs to learn from its past experiences in terms of policy design and implementation, and the need to implement dynamic policies that could spur productive and sustained growth and development by tackling challenges associated with the continuously evolving global economic environment.

The Oxford Handbook of the Malawi Economy (Oxford Handbooks)


The Oxford Handbook of the Malawi Economy is an essential reference material with new research contributions and insights across the different areas of economic development to shape the country's future growth and development trajectory. The volume is the first publication that tries to assess the performance of the Malawi economy since independence, by examining how the underpinning political and economic history, and the associated policies and strategies have affected the country's long-term socio-economic development. It captures a broad range of opinions, approaches, and conclusions, which serve to underline both the complexity of the issues and challenges facing Malawi, and the immense difficulties in tackling them. Common themes emerge as many authors agree that the country needs to learn from its past experiences in terms of policy design and implementation, and the need to implement dynamic policies that could spur productive and sustained growth and development by tackling challenges associated with the continuously evolving global economic environment.

The Oxford History of Poetry in English: Volume 5. Seventeenth-Century British Poetry (Oxford History of Poetry in English)

by Laura L. Knoppers

The Oxford History of Poetry in English (OHOPE) is designed to offer a fresh, multi-voiced, and comprehensive analysis of 'poetry': from Anglo-Saxon culture through contemporary British, Irish, American, and Global culture, including English, Scottish, and Welsh poetry, Anglo-American colonial and post-colonial poetry, and poetry in Canada, Australia, New Zealand, the Caribbean, India, Africa, Asia, and other international locales. OHOPE both synthesizes existing scholarship and presents cutting-edge research, employing a global team of expert contributors for each of the fourteen volumes. By taking as its purview the full seventeenth century, 1603-1700, this volume re-draws the existing literary historical map and expands upon recent rethinking of the canon. Placing the revolutionary years at the centre of a century of poetic transformation, and putting the Restoration back into the seventeenth century, the volume registers the transformative effects on poetic forms of a century of social, political, and religious upheaval. It considers the achievements of a number of women poets, not yet fully integrated into traditional literary histories. It assimilates the vibrant literature of the English Revolution to what came before and after, registering its long-term impact. It traces the development of print culture and of the literary marketplace, alongside the continued circulation of poetry in manuscript. It places John Milton, Andrew Marvell, Margaret Cavendish, and Katherine Philips and other mid-century poets into the full century of specifically literary development. It traces continuity and change, imitation and innovation in the full-century trajectory of such poetic genres as sonnet, elegy, satire, georgic, epigram, ode, devotional lyric, and epic. The volume's attention to poetic form builds on the current upswing in historicist formalism, allowing a close focus on poetry as an intensely aesthetic and social literary mode. Designed for maximum classroom utility, the organization is both thematic and (in the authors section) chronological. After a comprehensive Introduction, organizational sections focus on Transitions; Materiality, Production, and Circulation; Poetics and Form; Genres; and Poets.

Oxford Smart Mosaic: Student Book 1

by Ian Bettison Katie Wood Jemma Sherwood Dan Draper Charlotte Hawthorne Helen Konstantine

Part of the Oxford Smart Curriculum Service, Oxford Smart Mosaic is a responsive curriculum for KS3. The Student Book supports practice, fluency and connections, enabling Year 7 students to develop secure understanding first time. All students are supported to make the best possible progress, whatever their prior attainment.

Oxford Studies in Normative Ethics Volume 14 (Oxford Studies in Normative Ethics)

by Mark Timmons

Oxford Studies in Normative Ethics is an annual forum for new work in normative ethical theory. Leading philosophers present original contributions to our understanding of a wide range of moral issues and positions, from analysis of competing approaches to normative ethics (including moral realism, constructivism, and expressivism) to questions of how we should act and live well. OSNE is an essential resource for scholars and students working in moral philosophy.

Oxford Studies in Normative Ethics Volume 14 (Oxford Studies in Normative Ethics)


Oxford Studies in Normative Ethics is an annual forum for new work in normative ethical theory. Leading philosophers present original contributions to our understanding of a wide range of moral issues and positions, from analysis of competing approaches to normative ethics (including moral realism, constructivism, and expressivism) to questions of how we should act and live well. OSNE is an essential resource for scholars and students working in moral philosophy.

Oxford Studies in Philosophy of Mind: Volume 4 (Oxford Studies in Philosophy of Mind)


Oxford Studies in Philosophy of Mind presents cutting-edge work in the philosophy of mind, combining invited articles and articles selected from submissions. Each volume will highlight two themes to bring focus to debates. The series will reflect the diversity of methods adopted in contemporary philosophy of mind and provide a venue for rigorous and innovative work by both established and up-and-coming voices in the field. The themes covered in the fourth volume are twenty-first-century idealism, acquaintance and perception, and acquaintance and consciousness. It also contains a book symposium on David Chalmers' Reality+, and an article on Aristotle's philosophy of mind.

Oxidative Stress in Cardiovascular-Metabolic Diseases (Oxidative Stress in Applied Basic Research and Clinical Practice)

by Firas Kobeissy Ali Hussein Eid Ahmed F. El-Yazbi

The book dissects the role of oxidative stress in the pathogenesis of the leading causes of global morbidity and mortality, i.e. cardiovascular and metabolic diseases. The chapters discuss topics related to the role reactive oxygen species (ROS) play in hypertension, atherosclerosis, diabetes, obesity and related pathologies. One chapter discusses the clinical efficacy and safety considerations of GLP-1 receptor agonists and SGLT-2 inhibitors in obesity management and the associated cardiovascular complications. Another chapter discusses the context-dependent roles of matrix metalloproteases, and how their activity can be modulated and utilized for the development of improved drugs for cardiometabolic diseases. Moreover, how ROS and aging interplay to precipitate cardiovasculo-metabolic disease is discussed and highlighted. Similarly, how sex and sepsis interplay in the context of cardiorenal disease is teased out in one of the chapters. Preventive measures that can abrogate ROS-induced cardiovasclo-metabolic disease are discussed and clarified in the hope of reducing such a debilitating battery of diseases. Another chapter is fully dedicated to the roles of ROS in atherosclerosis, while another chapter deals with mechanisms and effect of ROS on various phenotypes of adipose tissues in the context of cardiovasculo-metabolic disease. A chapter also discusses the link between traumatic brain injury (TBI) and cardiovascular impairments, and how ROS plays a significant role in TBI-induced cardiovascular disease. A section dedicated to antioxidants as potential therapy is also included. Given the complexity of the mechanisms implicated in ROS-modulated responses, it remains challenging to assert a conclusive argument and pre-determined regimen for incorporating antioxidants into conventional therapies. In all of the chapters, the molecular, cellular, genetic, and pharmacological mechanisms implicated are covered from an applied science perspective. This is an ideal book for basic researchers in the biomedical field, graduate students in biological and biomedical fields, medical students, instructors in medical and graduate schools, and professionals working for pharmaceutical companies.

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