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Analysis File of Drug-Induced Lung Injury: Expert Opinion for Analysis of Big Data
by Akihiko GemmaThis book describes the pathologic conditions of drug-induced lung injuries, monitoring strategies, and guides on how to interpret the evidence. It also dives into particular drugs that caused the disorder, such as EGFR inhibitors, anti-EGFR antibodies, mTOR inhibitors, proteasome inhibitors, immune checkpoint inhibitors, neoangiogenesis inhibitors, and other molecular targeted drugs. It outlines the analysis and interpretation of the post-marketing survey on surveillance of each drug for inducing pulmonary lesions presenting diffuse haziness. The data and analysis from this survey are valuable since a guideline is yet to be established due to limited clinical evidence and cases. As new drugs are developed, establishing treatment and event management is crucial. Thus, Drug-induced Pulmonary Disorder in Medical Oncology - Expert Opinion to Decipher Big Data summarizes the accumulated information to provide a foundation for further research advancement. The book offers a refreshing alternative to current approaches to medical oncology and respiratory diseases professionals and will also attract medical affairs members in global pharmaceutical companies.
High Energy Efficiency Neural Network Processor with Combined Digital and Computing-in-Memory Architecture (Springer Theses)
by Jinshan YueNeural network (NN) algorithms are driving the rapid development of modern artificial intelligence (AI). The energy-efficient NN processor has become an urgent requirement for the practical NN applications on widespread low-power AI devices. To address this challenge, this dissertation investigates pure-digital and digital computing-in-memory (digital-CIM) solutions and carries out four major studies. For pure-digital NN processors, this book analyses the insufficient data reuse in conventional architectures and proposes a kernel-optimized NN processor. This dissertation adopts a structural frequency-domain compression algorithm, named CirCNN. The fabricated processor shows 8.1x/4.2x area/energy efficiency compared to the state-of-the-art NN processor. For digital-CIM NN processors, this dissertation combines the flexibility of digital circuits with the high energy efficiency of CIM. The fabricated CIM processor validates the sparsity improvement of the CIM architecture for the first time. This dissertation further designs a processor that considers the weight updating problem on the CIM architecture for the first time. This dissertation demonstrates that the combination of digital and CIM circuits is a promising technical route for an energy-efficient NN processor, which can promote the large-scale application of low-power AI devices.
Urban Spatial Evolution Simulation: Theory, Method, and Practice (Urban Sustainability)
by Fangqu NiuThis book provides a comprehensive introduction to the LUTI model from many aspects such as principles, methods and practice. Since the geometric revolution in the 1960s, model simulation methods have been used in some developed countries to study the development process of urban space and to support urban spatial decision making. One of the most common models is the Land Use Transport Interaction (LUTI) model. At present, relevant research is also gradually emerging in developing countries. This book has the following features: 1. The theory and methods of urban spatial development simulation have been systematically summarised, and practical application research has been carried out. 2. The LUTI model has been systematically explored from theory and implementation method to application practice. 3. The "activity-based" modelling techniques used are at the forefront of LUTI model development.
Advances in Distributed Computing and Machine Learning: Proceedings of ICADCML 2024, Volume 2 (Lecture Notes in Networks and Systems #1015)
by Kuan-Ching Li Asis Kumar Tripathy Mahasweta Sarkar Jyoti Prakash Sahoo Umakanta NandaThis book is a collection of peer-reviewed best selected research papers presented at the Fifth International Conference on Advances in Distributed Computing and Machine Learning (ICADCML 2024), organized by School of Electronics and Engineering, VIT - AP University, Amaravati, Andhra Pradesh, India, during 5–6 January 2024. This book presents recent innovations in the field of scalable distributed systems in addition to cutting edge research in the field of Internet of Things (IoT) and blockchain in distributed environments.
Data Storage Architectures and Technologies
by Jiwu ShuData is a core asset in the current development of information technology and needs to be stored efficiently and reliably to serve many important real-world applications such as the Internet, big data, artificial intelligence, and high-performance computing. Generations of researchers and practitioners have continued to innovate the design of storage systems to achieve the goals of high performance, ease of use, and high reliability. This textbook provides a thorough and comprehensive introduction to the field of data storage. With 14 chapters, the book not only covers the basics of storage devices, storage arrays, storage protocols, key-value stores, file systems, network storage architecture, distributed storage systems, storage reliability, storage security, and data protection, but also provides in-depth discussions on advanced topics such as storage maintenance, storage solutions, and storage technology trends and developments (e.g., in-storage computing, persistent memory system, blockchain storage, and in-network storage system). For each section, the authors have attempted to provide the latest current academic and industry research progress that will help readers deepen their understanding and application of basic data storage concepts. This textbook is ideal for storage courses targeting upper-level undergraduate or graduate students in computer science and related disciplines. It also serves as a valuable reference for technical professionals.
Innovative Computing and Communications: Proceedings of ICICC 2024, Volume 1 (Lecture Notes in Networks and Systems #1020)
by Aboul Ella Hassanien Sameer Anand Ajay Jaiswal Prabhat KumarThis book includes high-quality research papers presented at the Seventh International Conference on Innovative Computing and Communication (ICICC 2024), which is held at the Shaheed Sukhdev College of Business Studies, University of Delhi, Delhi, India, on 16–17 February 2024. Introducing the innovative works of scientists, professors, research scholars, students, and industrial experts in the field of computing and communication, the book promotes the transformation of fundamental research into institutional and industrialized research and the conversion of applied exploration into real-time applications.
India in the Arctic: Geopolitical and Economic Engagements
by Nikhil PareekThis book explores the pitfalls and bottlenecks of viewing the Arctic from a mere scientific prism and offers recommendations to approach it from a strategic construct and climate change by strengthening bilateral and multilateral cooperation with the Arctic states and the Arctic intergovernmental organisations. It discusses the inception and development of the soft law cooperative governance structure prevailing in the Arctic and explores engagement by the various stakeholders including the eight sovereign states, thirteen sovereign states as observers, various intergovernmental and inter-parliamentarian outfits, NGOs, and others desirous of an active participation in the Arctic. It brings out the geo-economic and geostrategic levers which have propelled the Arctic as a key region for emerging great power rivalry. It posits the efforts of Arctic states and the Observers holistically to draw parallels with the Indian efforts requiring greater focus and effort. It critically examines the Arctic Policy released by the government on 17 Mar 2022 that missed the opportunity to elucidate India’s geo-economic, geostrategic, economic, and geopolitical aspirations in the hugely vital region and debates if India’s economic and geopolitical position as well as historical links to the Arctic region fits the requirements of an external observer state and must continue to build on its strengths for mutual betterment.
Recent Advances in Materials and Manufacturing: Proceedings of ISME 2023 (Lecture Notes in Mechanical Engineering)
by C. V. Chandrashekara N. Rajesh Mathivanan K. HariharanThis book presents the select proceedings of 21st ISME conference on Advances in Mechanical Engineering. It covers the latest research and technological advancements in the area of manufacturing and materials engineering. Various topics covered in this book are additive manufacturing, rapid prototyping, micro and nano manufacturing, welding, casting, forming process, conventional and non-conventional machining, CIM, CAM, modeling and simulation, composite materials, powder metallurgy, supply chain management, reliability engineering/quality engineering product life cycle management, industry 4.0, micro machining, surface science and engineering, materials characterization and functionally graded materials. The book is useful for researchers and professionals working in the areas of manufacturing and materials engineering.
Real Analysis Methods for Markov Processes: Singular Integrals and Feller Semigroups
by Kazuaki TairaThis book is devoted to real analysis methods for the problem of constructing Markov processes with boundary conditions in probability theory. Analytically, a Markovian particle in a domain of Euclidean space is governed by an integro-differential operator, called the Waldenfels operator, in the interior of the domain, and it obeys a boundary condition, called the Ventcel (Wentzell) boundary condition, on the boundary of the domain. Most likely, a Markovian particle moves both by continuous paths and by jumps in the state space and obeys the Ventcel boundary condition, which consists of six terms corresponding to diffusion along the boundary, an absorption phenomenon, a reflection phenomenon, a sticking (or viscosity) phenomenon, and a jump phenomenon on the boundary and an inward jump phenomenon from the boundary. More precisely, we study a class of first-order Ventcel boundary value problems for second-order elliptic Waldenfels integro-differential operators. By using the Calderón–Zygmund theory of singular integrals, we prove the existence and uniqueness of theorems in the framework of the Sobolev and Besov spaces, which extend earlier theorems due to Bony–Courrège–Priouret to the vanishing mean oscillation (VMO) case. Our proof is based on various maximum principles for second-order elliptic differential operators with discontinuous coefficients in the framework of Sobolev spaces. My approach is distinguished by the extensive use of the ideas and techniques characteristic of recent developments in the theory of singular integral operators due to Calderón and Zygmund. Moreover, we make use of an Lp variant of an estimate for the Green operator of the Neumann problem introduced in the study of Feller semigroups by me. The present book is amply illustrated; 119 figures and 12 tables are provided in such a fashion that a broad spectrum of readers understand our problem and main results.
Jet Transport Technique: Theory and Application
by Gerard Gómez Josep J. Masdemont Chen Gao Jianlin Chen Jianping Yuan Chuan MaThis book focuses on the Jet Transport (JT) technique and gives a systematic introduction on its theory development, algorithm implementation, and in particular, the applications in the field of astronautics including uncertainty propagation, filtering, as well as guidance and control. It features on the combination of mathematical theory and engineering applications, making the technique to be understood and mastered straightforwardly. Moreover, the JT-based methods proposed in the book offer a new and ingenious way to some classical problems. Given its breadth of coverage, the book offers a valuable reference guide for researchers and engineers interested in the JT methodology including theory and applications.
Proceedings of the 14th International Conference on Sustainable Built Environment: ICSBE 2023, 15th–17th December, Kandy, Sri Lanka (Lecture Notes in Civil Engineering #517)
by Ranjith Dissanayake Priyan Mendis Sudhira De Silva Shiromal Fernando Chaminda Konthesingha Upul Attanayake Pradeep GajanayakeThis book highlights the latest knowledge and innovations in the fields of civil engineering and construction industry striving for a sustainable built environment. This book consists of high-quality innovative research findings selected from the proceedings of the 14th International Conference on Sustainable Built Environment (ICSBE 2023) under the themes of Sustainable construction, urban green infrastructure and planning, rainwater harvesting and water conservation, high-performance concrete, indoor environmental quality and indoor plants, wind and hydro-power energy, waste and wastewater management for enhanced sustainability, impacts of climate change, carbon footprint, global climate model and landscaping, material flows and industrial ecology, sustainable materials, etc.
Brain and Mathematical Cognition: Evidence from China
by Xinlin ZhouThis book intends to present a series of insights coming from in-depth investigation of brain and mathematical cognition in Chinese population. Specifically, the book introduces research on the associations among number sense, visual form perception and mathematical fluency; symbolic and non-symbolic mental number line; and the role of spatial modeling and logical inference in mathematical problem solving. The book summarizes author's previous studies on the involvement of semantic network other than visuospatial network in mathematical cognition. The three-component mathematical model that comes out of more than 10 years of research on mathematical cognition is introduced. The book presents the effect of learning experience on arithmetic-related brain system. Chinese abacus that can be used to eradicate developmental dyscalculia in classroom is briefly discussed. Special attention in this book is paid to mathematical anxiety and mathematical learning disorders in Chinese schoolchildren. Finally, gender differences in mathematical cognition are also reviewed.
Human Microbiome: Techniques, Strategies, and Therapeutic Potential
by Muhammad Sajid Hamid Akash Mohsin KhurshidThis book is a comprehensive guide on microbiome research, from the fundamentals of to the latest advancements in microbiome-based therapeutics. The initial chapters introduce the concept of the human microbiome delving into the intricate relationship between the human host and its microbiome. The chapter also examines the various tools and techniques used in microbiome research and the role of computational biology in analyzing vast amounts of microbiome data. The subsequent chapters review the role of the microbiome in various health conditions, including metabolic disorders, immunological disorders, gastrointestinal tract disorders, management of cancers, metabolic disorders, and mental health disorders. Towards the end, the book examines the regulatory considerations surrounding microbiome-based therapeutics, and ethical considerations surrounding microbiome-based therapeutics. This book is a comprehensive and cutting-edge guide for researchers, healthcare professionals, and students interested in the field of microbiome research and its potential for transforming healthcare.
Creative Textile Industry: Past, Present and Future of South Asian Countries (SDGs and Textiles)
by Hafsa Jamshaid Allah DadThis book gives a comprehensive overview of the creative textile industry and its sectors involved in South Asian countries namely Pakistan, India, and Bangladesh. It provides basic knowledge about the textile, fabric manufacturing techniques, processing, and design method used for the development of creative textile products from the three countries in the past till the 1900s to the present 2023 and discusses the future challenges and prospects. It introduces the concept of a multi-species design process as the future need to obtain a sustainable product cycle of creative textile fabrics. The content of this book appeals to academic researchers, industrial practitioners, and policymakers who are interested in the creative textile industry in South Asia, its economics, and sustainability.
Universal Threats in Expert Applications and Solutions: Proceedings of 3rd UNI-TEAS 2024, Volume 1 (Lecture Notes in Networks and Systems #1006)
by Vijay Singh Rathore Joao Manuel R. S. Tavares B. Surendiran Anil YadavThis book presents high-quality, peer-reviewed papers from 3rd International Conference on “Universal Threats in Expert Applications and Solutions" (UNI-TEAS 2024), jointly being organized by IES University, Bhopal, and Shree KKarni Universe College, Jaipur, in association with CSI Jaipur Chapter and Jaipur ACM Professional Chapter during January 6–9, 2024. The book is a collection of innovative ideas from researchers, scientists, academicians, industry professionals, and students. The book covers a variety of topics, such as expert applications and artificial intelligence/machine learning; advance web technologies such as IoT, big data, cloud computing in expert applications; information and cyber security threats and solutions, multimedia applications in forensics, security and intelligence; advancements in app development; management practices for expert applications; and social and ethical aspects in expert applications through applied sciences.
Innovative Computing and Communications: Proceedings of ICICC 2024, Volume 4 (Lecture Notes in Networks and Systems #1024)
by Aboul Ella Hassanien Sameer Anand Ajay Jaiswal Prabhat KumarThis book includes high-quality research papers presented at the Seventh International Conference on Innovative Computing and Communication (ICICC 2024), which is held at the Shaheed Sukhdev College of Business Studies, University of Delhi, Delhi, India, on 16–17 February 2024. Introducing the innovative works of scientists, professors, research scholars, students, and industrial experts in the field of computing and communication, the book promotes the transformation of fundamental research into institutional and industrialized research and the conversion of applied exploration into real-time applications.
Geoenvironmental Engineering: Proceedings of EGRWSE-23, Volume 1 (Lecture Notes in Civil Engineering #508)
by Krishna R. Reddy Arvind Kumar Agnihotri Ajay BansalThis book contains peer-reviewed and selected papers presented during the International Conference on Environmental Geotechnology, Recycled Waste Materials and Sustainable Engineering (EGRWSE) 2023, held at NIT Jalandhar. It discusses the recent innovations, trends, concerns, practical challenges encountered, and the solutions adopted in waste management and engineering, geotechnical and geoenvironmental engineering, infrastructure engineering and sustainable engineering. This book can serve as a useful resource for researchers, educators, policymakers, and professionals working in the field of civil engineering, chemical engineering, environmental sciences, and public policy.
Intelligent Bridge Maintenance and Management: Emerging Digital Technologies (Springer Tracts in Civil Engineering)
by Gang Wu Ji Dang ZhiQiang ChenThis book provides a timely introduction to the methodology of Intelligent Bridge Maintenance and Management (IBM&M) and a comprehensive synthesis of emerging digital technologies for realizing IBM&M. The authors, who carry research, teaching, and consulting experience in the USA, Japan, and China, present the background, principles, methods, and application examples of essential IBM&M solutions in eight dedicated chapters. The digital technologies covered in this book include: • Artificial intelligence, big data, machine learning, computer vision. • Data fusion, 3D building information, digital twin modeling, virtual and augmented reality. • Internet of things sensors, robotics including unmanned vehicles. The book targets the audience in the broader Bridge Engineering community, including academic researchers, students, bridge owners, and technology providers.
Smart Road Infrastructure: Ideas, Innovations and Emerging Technologies (Lecture Notes in Intelligent Transportation and Infrastructure)
by Xingyi ZhuThis book focuses on the fundamental ideas in the future smart transportation infrastructure systems that, in turn, give rise to new architectures and applications of emerging technologies. Although the scope of transportation infrastructure systems is very broad, this book focuses in detail on the main one—urban road infrastructure systems. Based on the investigation of the development trend and current situation of the smart road infrastructure (SRI), this book clarifies the connotation, architecture, and implementation path of the SRI. Emerging technologies related to SRI have also been summarized, which is useful for SRI design and construction. The book is intended for undergraduate and graduate students who are interested in the SRI technology or intelligent transportation systems and road/transportation design engineers working on relevant projects.
Climate Change and Regional Socio-Economic Systems in the Global South: Resilience Strategies for Sustainable Development
by Mukunda Mishra Andrews José de Lucena Brij MaharajThis volume showcases how the climate change phenomena (CCP) have been causing multifaceted threats to humankind through increasing numbers of extreme events, affecting social, economic, and human development worldwide. The Global South is especially showcased in this contributory volume where adverse effects of CCP and related disasters impact majority of the population which depends on land and natural resources for their livelihoods. This book asserts that climate change and extreme events are potential threats to sustainable human development and micro spatial observations and analysis of impacts of CCP are vital for adopting resilience policies. This book, not enquiring why CCP is happening, embarks on a quest to showcase how best to respond to such phenomena through detailed and well-founded micro-spatial investigations on poor farmers, pastoralists, fishermen folk, migrant labours, slum dwellers, who are considered the most threatened by climate changes and weather shocks, based on possible disruptions in the production process. Scholarly contributions in this volume analyze how local and regional versions of CCP actively challenge the economies and livelihoods, question the social securities and good governance, and how such phenomena ultimately become a constraint in achieving sustainable development in the Global South. This volume accommodates many aspects of regional adaptation strategies in vulnerable areas and groups in different parts of the Global South to ensure stability and peacefulness. Academicians, research scholars, and readers inquisitive about the socio-economic dimensions of climate change in the Global South, will find the discussions across different chapters of this volume interesting.
Molecular Simulation Investigations of Property Degradation in CFRP Composite
by Chao Wu Lik-ho Tam Ruidong Wu Jia-ao HouThis book is written by a group of researchers based on the recent research progress in the fiber/matrix interface degradation under various environmental exposures via molecular dynamics simulation. It provides systematic framework of the model development, simulation techniques, and simulation results and presents the future research directions for investigating the interfacial degradation. By introducing the molecular details of fiber/matrix interface under environmental effects, it advances the fundamental understanding of the interfacial degradation mechanism. Researchers, scientists and engineers in the field of civil engineering and composite materials can benefit from the book. In conclusion, this book provides a computational paradigm and valuable insights on the fundamental interfacial degradation mechanism, which can contribute to the prediction of long-term behavior of fiber-reinforced polymer composites in harsh environments and pave the way for the material design with stronger interface.
Forests and Climate Change: Biological Perspectives on Impact, Adaptation, and Mitigation Strategies
by Hukum SinghThis book comprehensively examines the complex relationship between forests and climate change from a biological perspective. It explores the effects of climate change, such as rising temperatures, greenhouse gas emissions, changing rainfall patterns, droughts, and cold spells, on individual trees and forest ecosystems. It considers how climate change affects forest structure, function, composition, and biodiversity, and the adaptive strategies forests employ to cope with changing conditions. The book focuses on understanding the adaptive capacity of forests and explores different mechanisms at stand and ecosystem levels that enable forests to respond to changing climatic conditions. It discusses how forests acclimate and adapt to new climates by modulating growth rates, morphology, phenology, physiology, biochemistry, and species composition. The role of genetic diversity and evolutionary processes in shaping forest resilience and adaptation is also explored. The book also explores potential mitigation strategies to reduce the impacts of climate change. Besides, this book discusses the ecological principles and the involvement of local communities in conservation and restoration efforts as alternative strategies to enhance the resilience of forest ecosystems against climate change. The book provides practical recommendations for policy makers, forest managers, and conservation practitioners to develop effective climate change adaptation and mitigation strategies in forest landscapes. This book serves as a valuable resource and a guide for researchers, students, and professionals in various fields to protect and sustainably manage vital ecosystems in a rapidly changing climate.
Women with Epilepsy in Child-bearing Age: Diagnosis and Treatment
by Lei ChenThis book aims to collect research findings and provide insightful recommendations on various aspects of female epilepsy patients of childbearing age. This book discusses multidisciplinary effort of brain science, reproductive medicine, endocrinology, drug metabolism, genetics, maternal and infant medicine, etc. This book is written by a multidisciplinary team of researchers who had a passion for improving the quality of life of women with epilepsy, to demonstrate the latest scientific discoveries and precise management strategies for women with epilepsy in child-bearing age.
Biomaterial-Inspired Nanomedicines for Targeted Therapies
by Nagendra Singh Chauhan Madhulika Pradhan Krishna YadavThis book delves into the burgeoning field of nano-biomaterials and their application in targeted drug delivery across various therapeutic domains. Through its comprehensive exploration, it offers insights into the innovative approaches and potential of biomaterial-inspired nanomedicines in revolutionizing healthcare. Chapter 1 introduces readers to the fundamental concepts of biomaterial-inspired nanomedicines, laying the groundwork for subsequent discussions. Chapter 2 delves into the utilization of nano-biomaterials in tissue engineering, highlighting their role in regenerative medicine. The book further examines the targeting of specific physiological barriers, such as the blood-brain barrier (Chapter 3), and explores the opportunities and challenges in biomaterial-based vaccine delivery (Chapter 4). Additionally, it discusses the use of nano-biomaterials in addressing pulmonary obstruction (Chapter 5) and targeting the tumor microenvironment for chemotherapy (Chapter 6). Chapters 7 to 16 explore various therapeutic applications of nano-biomaterials across different medical conditions, including autoimmune skin disorders, diabetes, wound healing, central nervous system disorders, ocular diseases, infectious diseases, musculoskeletal disorders, and gastrointestinal diseases. Furthermore, the book sheds light on advances in nano-biomaterials for effective antimicrobial therapy and offers insights into the clinical and regulatory considerations associated with their use (Chapter 17). By encompassing a wide range of topics and providing in-depth analyses, "Biomaterial-Inspired Nanomedicines for Targeted Therapies" serves as a valuable resource for researchers, practitioners, and policymakers aiming to leverage the potential of nano-biomaterials in improving healthcare outcomes.
Practical Machine Learning Illustrated with KNIME
by Yu Geng Qin Li Geng Yang Wan QiuThis book guides professionals and students from various backgrounds to use machine learning in their own fields with low-code platform KNIME and without coding. Many people from various industries need use machine learning to solve problems in their own domains. However, machine learning is often viewed as the domain of programmers, especially for those who are familiar with Python. It is too hard for people from different backgrounds to learn Python to use machine learning. KNIME, the low-code platform, comes to help. KNIME helps people use machine learning in an intuitive environment, enabling everyone to focus on what to do instead of how to do. This book helps the readers gain an intuitive understanding of the basic concepts of machine learning through illustrations to practice machine learning in their respective fields. The author provides a practical guide on how to participate in Kaggle completions with KNIME to practice machine learning techniques.