Solid-State Properties of Pharmaceutical Materials

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Synopsis

Presents a detailed discussion of important solid-state properties, methods, and applications of solid-state analysis Illustrates the various phases or forms that solids can assume and discussesvarious issues related to the relative stability of solid forms and tendencies to undergo transformation Covers key methods of solid state analysis including X-ray powder diffraction, thermal analysis, microscopy, spectroscopy, and solid state NMR Reviews critical physical attributes of pharmaceutical materials, mainly related to drug substances, including particle size/surface area, hygroscopicity, mechanical properties, solubility, and physical and chemical stability Showcases the application of solid state material science in rational selection of drug solid forms, analysis of various solid forms within drug substance and the drug product, and pharmaceutical product development Introduces appropriate manufacturing and control procedures using Quality by Design, and other strategies that lead to safe and effective products with a minimum of resources and time

Book details

Author:
Stephen R. Byrn, George Zografi, Xiaoming (Sean) Chen
ISBN:
9781119264453
Related ISBNs:
9781119264408, 9781118145302
Publisher:
Wiley
Pages:
N/A
Reading age:
Not specified
Includes images:
Yes
Date of addition:
2019-08-04
Usage restrictions:
Copyright
Copyright date:
2017
Copyright by:
Wiley 
Adult content:
No
Language:
English
Categories:
Nonfiction, Science