Comprehensive Analysis of Parasite Biology From Metabolism to Drug Discovery

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Synopsis

Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa. The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state-of the art "omics" technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification. In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented.

Book details

Series:
Drug Discovery in Infectious Diseases
Author:
Paul M. Selzer
ISBN:
9783527694099
Related ISBNs:
9783527694082, 9783527694082, 9783527339044
Publisher:
Wiley
Pages:
576
Reading age:
Not specified
Includes images:
No
Date of addition:
2019-10-22
Usage restrictions:
Copyright
Copyright date:
2016
Copyright by:
N/A 
Adult content:
No
Language:
English
Categories:
Medicine, Nonfiction