Retinal Degenerations Mechanisms and Experimental Therapy

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Synopsis

The topics in this volume explore the etiology, cellular mechanisms, epidemiology, genetics, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration.Special focus is highlighted in the areas of Mechanisms of Photoreceptor Degeneration and Cell Death (extremely important because very little is known how or why photoreceptors die in these diseases, despite an abundance of genetic information), Age-Related Macular Degeneration (with several novel approaches to its analysis), Usher Syndrome (the most severe form of retinitis pigmentosa, which includes an early or congenital loss of hearing along with blindness), and Gene Therapy. In addition, the section on Basic Science Related to Retinal Degeneration is particularly strong with several laboratories reporting on new discoveries in the area of outer segment phagocytosis, a key component of photoreceptor-retinal pigment epithelial cell interactions in normal and degenerating retinas.

Book details

Edition:
2003
Series:
Advances in Experimental Medicine and Biology (Book 533)
Author:
Matthew M. LaVail, Joe G. Hollyfield, Robert E. Anderson
ISBN:
9781461500674
Related ISBNs:
9780306477812
Publisher:
Springer US
Pages:
N/A
Reading age:
Not specified
Includes images:
No
Date of addition:
2021-01-08
Usage restrictions:
Copyright
Copyright date:
2003
Copyright by:
N/A 
Adult content:
No
Language:
English
Categories:
Medicine, Nonfiction, Outdoors and Nature