Enzyme Kinetics in Drug Metabolism Fundamentals and Applications

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Synopsis

This second edition further develops the principles of applying kinetic principles to drug metabolizing enzymes and transporters. Chapters are divided into six sections detailing fundamental principles of enzyme kinetics, enzyme and transporter structures, highlighting specific oxidative and conjugative drug metabolizing enzymes and drug transporters, modeling approaches for drug metabolizing enzymes and transporters, understanding of variability both experimental and interindividual (pharmacogenomic), and expanded case studies that provide real life examples of applying these principles. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, in some cases step-by-step instructions with readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls with extensive cross referencing to assist in learning. 

 

Authoritative and fully updated, Enzyme Kinetics in Drug Metabolism: Fundamentals and Applications, Second Edition serves as a practical teaching tool for novice and advanced scientists interested in the fundamental concepts.

Book details

Edition:
2nd ed. 2021
Series:
Methods in Molecular Biology (Book 2342)
Author:
Swati Nagar, Upendra A. Argikar, Donald Tweedie
ISBN:
9781071615546
Related ISBNs:
9781071615539
Publisher:
Springer US
Pages:
N/A
Reading age:
Not specified
Includes images:
Yes
Date of addition:
2021-08-16
Usage restrictions:
Copyright
Copyright date:
2021
Copyright by:
Springer Science+Business Media, LLC, part of Springer Nature 
Adult content:
No
Language:
English
Categories:
Medicine, Nonfiction, Science