Formulating Poorly Water Soluble Drugs
Synopsis
The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.Book details
- Edition:
- 3rd ed. 2022
- Series:
- AAPS Advances in the Pharmaceutical Sciences Series (Book 50)
- Author:
- Robert O. Williams, Daniel A. Davis, Dave A. Miller
- ISBN:
- 9783030887193
- Related ISBNs:
- 9783030887186
- Publisher:
- Springer International Publishing
- Pages:
- N/A
- Reading age:
- Not specified
- Includes images:
- Yes
- Date of addition:
- 2022-06-19
- Usage restrictions:
- Copyright
- Copyright date:
- 2022
- Copyright by:
- American Association of Pharmaceutical Scientists
- Adult content:
- No
- Language:
- English
- Categories:
- Medicine, Nonfiction, Science