Total Chemical Synthesis of Proteins

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Synopsis

How to synthesize native and modified proteins in the test tube  With contributions from a panel of experts representing a range of disciplines, Total Chemical Synthesis of Proteins presents a carefully curated collection of synthetic approaches and strategies for the total synthesis of native and modified proteins.    Comprehensive in scope, this important reference explores the three main chemoselective ligation methods for assembling unprotected peptide segments, including native chemical ligation (NCL). It includes information on synthetic strategies for the complex polypeptides that constitute glycoproteins, sulfoproteins, and membrane proteins, as well as their characterization. In addition, important areas of application for total protein synthesis are detailed, such as protein crystallography, protein engineering, and biomedical research.  The authors also discuss the synthetic challenges that remain to be addressed. This unmatched resource:  Contains valuable insights from the pioneers in the field of chemical protein synthesis  Presents proven synthetic approaches for a range of protein families  Explores key applications of precisely controlled protein synthesis, including novel diagnostics and therapeutics  Written for organic chemists, biochemists, biotechnologists, and molecular biologists, Total Chemical Synthesis of Proteins provides key knowledge for everyone venturing into the burgeoning field of protein design and synthetic biology.   

Book details

Author:
Lei Liu, Ashraf Brik, Philip Dawson
ISBN:
9783527823574
Related ISBNs:
9783527346608, 9783527823567
Publisher:
Wiley
Pages:
624
Reading age:
Not specified
Includes images:
No
Date of addition:
2022-07-11
Usage restrictions:
Copyright
Copyright date:
2021
Copyright by:
N/A 
Adult content:
No
Language:
English
Categories:
Nonfiction, Science