Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progrès Dans la Chimie des Substances Organiques Naturelles

Synopsis

In agreement with SCHLENK (I78) "nucleotide" is here taken to mean a phosphoric ester of an N-glycoside of a heterocyclic base. Although they fall outside the scope of this definition, phosphorylated derivatives of riboflavin are added in recognition of their close relation to the main body of nucleotides. A complete review of even the organic chemistry of nucleotides and their derivatives would now form a substantial monograph. The smaller and less characteristic fragments of the nucleotides, namely the hetero­ cyclic bases, the component sugars and the derived sugar phosphates, are therefore excluded from this article. * Their chemistry is of longer standing and is covered in standard works. On the other hand knowledge of the "nucleosides", the N-glycosides of heterocyclic bases, has expanded very considerably in recent years and an account of the relevant work is therefore included. With regard to the nucleotides themselves attention is focussed on work published in the last few years leading to improved characterisation, more exact structural knowledge and increased availa­ biIity. Only such enzymatic experiments as bear direct1y on structural problems are discussed and therefore much fascinating work by KALCKAR, FRIEDKIN et al. and by KORN BERG has been omitted. I t would be unthinkable to present a review on nucleotides without mentioning that the foundations of the subject were laid by P. A. LEVENE. His monograph with BASS (I36) was published in 1931 and two reviews by LYTHGOE (I50, I5I) cover the intervening period until 1944.

Book details

Edition:

1951

Series:

Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products (Book 8)

Author:

Y. Asahina, R. B. Corey, A. Frey-Wyssling, F. Galinovsky, G. W. Kenner, L. F. Leloir, K. Mühlethaler, M. Pailer, C. R. Ricketts, M. Rohdewald, H. Schinz, M. Stacey, L. Zechmeister

ISBN:

9783709171721

Related ISBNs:

9783211802045

Publisher:

Springer Vienna

Pages:

N/A

Reading age:

Not specified

Includes images:

No

Date of addition:

2022-08-15

Usage restrictions:

Copyright

Copyright date:

1951

Copyright by:

N/A 

Adult content:

No

Language:

English, German

Categories:

Medicine, Nonfiction, Science