Drug Metabolism Handbook Concepts and Applications in Cancer Research

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Synopsis

A comprehensive explanation of drug metabolism concepts and applications in drug development and cancer treatment In the newly revised second edition of Drug Metabolism Handbook: Concepts and Applications in Cancer Research, a distinguished team of researchers delivers an incisive and robust exploration of the drug metabolism system and a well-illustrated and detailed explanation of the latest tools and techniques used in the research, pharmacology, and medicine. The book discusses the creation of new molecular entities, drug development, troubleshooting, and other highly relevant concepts, guiding readers through new applications in pharmaceutical research, development, and assessment. The latest edition offers updated content on metabolism basics and the application of a variety of new techniques to cancer treatment, including mass spectrometry, imaging, metabolomics, and immunotherapy. It also offers in-depth case studies highlighting the role of metabolism in drug development. Readers will also benefit from: A thorough introduction to drug metabolism, including a historical perspective, factors affecting metabolism, and biotransformations in drug metabolism Comprehensive discussions of technologies for in vitro and in vivo studies, including mass spectrometry and accelerating metabolite identification with mass spectrometry In-depth explorations of drug interactions, including discussions of enzyme inhibition and the characterization of cytochrome P450 mechanism-based inhibition Fulsome treatments of drug toxicity, including the role of drug metabolism in toxicity, and allergic reactions to drugsPerfect for medicinal chemists, pharmaceutical scientists, and toxicologists, Drug Metabolism Handbook: Concepts and Applications in Cancer Research, Second Edition will also earn a place in the libraries of analytical chemists and drug discovery professionals.

Book details

Edition:
2
Author:
Paul F. Hollenberg, JoAnn Scatina, Soumen Kanti Manna, Su Zeng
ISBN:
9781119851035
Related ISBNs:
9781119851042, 9781119851011
Publisher:
Wiley
Pages:
1056
Reading age:
Not specified
Includes images:
Yes
Date of addition:
2022-11-19
Usage restrictions:
Copyright
Copyright date:
2023
Copyright by:
John Wiley & Sons, Inc. 
Adult content:
No
Language:
English
Categories:
Medicine, Nonfiction, Science