Genetically Incorporated Non-Canonical Amino Acids Methods and Protocols
Synopsis
This detailed volume explores non-canonical amino acids (ncAAs) through their site-specific incorporation by genetic code expansion (GCE). The collection provides a broad resource of methods for implementing GCE in E. coli, mammalian cells, and animals, highlighting specific applications ranging from fluorescence labeling to photocontrol and the study of protein post-translational modification. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Genetically Incorporated Non-Canonical Amino Acids: Methods and Protocols serves as an ideal source of methodologies that can be adapted and extended, migrated to different model systems, and combined in new ways to help explore a wide range of biological questions and to augment industrial and pharmaceutical protein engineering.
Book details
- Edition:
- 1st ed. 2023
- Series:
- Methods in Molecular Biology (Book 2676)
- Author:
- Yu-Hsuan Tsai, Simon J. Elsässer
- ISBN:
- 9781071632512
- Related ISBNs:
- 9781071632505
- Publisher:
- Springer US
- Pages:
- N/A
- Reading age:
- Not specified
- Includes images:
- Yes
- Date of addition:
- 2023-07-06
- Usage restrictions:
- Copyright
- Copyright date:
- 2023
- Copyright by:
- The Editor
- Adult content:
- No
- Language:
-
English
- Categories:
-
Nonfiction, Science